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Christophe Lechauve
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Journal Articles

Loss of miR-144/451 alleviates β-thalassemia by stimulating ULK1-mediated autophagy of free α-globin

Julia Keith, Georgios E. Christakopoulos, Alfonso G. Fernandez, Yu Yao, Jingjing Zhang, Kalin Mayberry, Rahul Telange, Razan B. A. Sweileh, Michael Dudley, Camilla Westbrook, Heather Sheppard, Mitchell J. Weiss, Christophe Lechauve
Journal: Blood
Blood (2023) 142 (10): 918–932.
https://doi.org/10.1182/blood.2022017265
Published: 2023
Includes: Supplemental data
Journal Articles

Regulation of gene expression by miR-144/451 during mouse erythropoiesis

Peng Xu, Lance E. Palmer, Christophe Lechauve, Guowei Zhao, Yu Yao, Jing Luan, Anastasios Vourekas, Haiyan Tan, Junmin Peng, John D. Schuetz, Zissimos Mourelatos, Gang Wu, Mitchell J. Weiss, Vikram R. Paralkar
Journal: Blood
Blood (2019) 133 (23): 2518–2528.
https://doi.org/10.1182/blood.2018854604
Published: 2019
Includes: Supplemental data
Journal Articles

Activation of ULK1 Kinase Mediates Clearance of Free Alpha-Globin in Human Beta-Thalassemic Erythroblasts

Christophe Lechauve, PhD, Julia Keith, Eugene Khandros, MD PhD, Stephanie Fowler, Kalin Mayberry, Abdullah Freiwan, Christopher Thom, MD PhD, Jingjing Zhang, Heather Tillman, DVM, PhD, Mondira Kundu, MD PhD, Irene Motta, MD, Maria Domenica Cappellini, MD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 411.
https://doi.org/10.1182/blood-2018-99-113901
Published: 2018
Journal Articles

Ulk1 Kinase Mediates Clearance of Free α-Globin in β-Thalassemia

Christophe Lechauve, PhD, Eugene Khandros, MD PhD, Christopher Thom, MD PhD, Abdullah Freiwan, Stephanie Fowler, Kalin Mayberry, Julia Keith, Heather Tillman, DVM, PhD, Mondira Kundu, MD PhD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 285.
https://doi.org/10.1182/blood.V130.Suppl_1.285.285
Published: 2017
Journal Articles

Erythroid miRNA-144/451 Binds Many mRNAs but Regulates Only a Small Subset

Vikram R Paralkar, MD, Lance Palmer, PhD, Peng Xu, PhD, Christophe Lechauve, PhD, Guowei Zhao, PhD, Yu Yao, MD, Gang Wu, PhD, Jing Luan, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1198.
https://doi.org/10.1182/blood.V128.22.1198.1198
Published: 2016
Journal Articles

Endothelial Cell-Expressed α Hemoglobin and Its Molecular Chaperone Ahsp Modulate Arterial Vascular Reactivity

Christophe Lechauve, PhD, Joshua Butcher, PhD, Abdullah Freiwan, Miranda Good, PhD, Sharon Frase, PhD, Heather Tillman, PhD, Brant Isakson, PhD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2016) 128 (22): 557.
https://doi.org/10.1182/blood.V128.22.557.557
Published: 2016