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Chunliang Li
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Journal Articles

Non-Canonical Transcription Activator Activity of RNA-Binding Protein MBNL1 Uniquely Controls FLT3 expression in MLL-Rearranged Leukemias

Siqi Yi, Shaela Wright, Meixia Che, Judith Hyle, Shelby Mryncza, Beisi Xu, Yong Cheng, Yajun Jiang, Chunliang Li
Journal: Blood
Blood (2023) 142 (Supplement 1): 2760.
https://doi.org/10.1182/blood-2023-185123
Published: 2023
Journal Articles

RNA-Binding Protein RBM5 Plays an Essential Role in Acute Myeloid Leukemia By Activating the Oncogenic Protein HOXA9

Mengli Zhang, Shaela Wright, Xiaowen Chen, Ye Xin, Yingcai Jin, Jianxiang Zhang, Xue Yang, Xinfeng Chen, Judith Hyle, Wojciech Rosikiewicz, Beisi Xu, Liusheng He, Feiqiu Wen, Chunliang Li, Peng Xu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4130.
https://doi.org/10.1182/blood-2023-182595
Published: 2023
Journal Articles

Genetic and Epigenetic Cis -Regulatory Disruptions Impacting the Canonical Wnt Signaling Repressor TLE1 Gene Promote Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia

Brennan P. Bergeron, Jonathan D. Diedrich, Yang Zhang, Kelly R. Barnett, Qian Dong, Daniel Ferguson, Robert J Autry, Wenjian Yang, Baranda S Hansen, Colton A Smith, Kristine R. Crews, Yiping Fan, Ching-Hon Pui, Shondra Miller, Mary V. Relling, Jun J. Yang, Chunliang Li, William E. Evans, Daniel Savic
Journal: Blood
Blood (2022) 140 (Supplement 1): 8838–8839.
https://doi.org/10.1182/blood-2022-166973
Published: 2022
Journal Articles

Systematically Interrogating Downstream Regulation Mechanisms of HOXA9 in MLL-r Leukemia Via Functional Noncoding CRISPR Screens

Chunliang Li, Shaela Wright, Xuijie Zhao, Shelby Mryncza, Beisi Xu
Journal: Blood
Blood (2022) 140 (Supplement 1): 1269–1270.
https://doi.org/10.1182/blood-2022-159186
Published: 2022
Journal Articles

ETV6 Represses TNF during Stress Hematopoiesis and Regulates HSC Self Renewal

Mackenzie Bloom, Rebekah Baskin-Doerfler, Ninad Oak, Ruopeng Feng, Xujie Zhao, Chunliang Li, Patrick Ozark, Katherine Verbist, Alexa Stroh, Sabrin Albeituni, JaQuel Maise, Mitchell J. Weiss, Shannon McKinney-Freeman, Jun J.J. Yang, Kim E. Nichols
Journal: Blood
Blood (2022) 140 (Supplement 1): 2849–2850.
https://doi.org/10.1182/blood-2022-168076
Published: 2022
Journal Articles

Activating a Non-Genetic MYC-Regulating Pathway Sensitizes Acute Myeloid Leukemia to Bromodomain Inhibition

Xinyue Zhou, Steven Moreira, Hong Wang, Pengcheng Zhang, Yang Zhou, Ravi Bhatia, Chunliang Li, Kristin Hope, Rui Lu
Journal: Blood
Blood (2022) 140 (Supplement 1): 8735.
https://doi.org/10.1182/blood-2022-167049
Published: 2022
Journal Articles

Interrogating Novel Bromodomain Inhibition Resistance Mechanism in Mllr Leukemia

Chunliang Li, Shaela Wright, Jianzhong Hu, Yang Zhang, Judith Hyle, Rui Lu
Journal: Blood
Blood (2021) 138 (Supplement 1): 26.
https://doi.org/10.1182/blood-2021-147003
Published: 2021
Journal Articles

Mapping the Glucocorticoid Gene Regulatory Network and Alterations That Contribute to Steroid Resistance in Childhood Acute Lymphoblastic Leukemia

Brennan P. Bergeron, Jonathan Diedrich, Yang Zhang, Qian Dong, Daniel Ferguson, Robert J Autry, Wenjian Yang, Baranda S Hansen, Kristine R. Crews, Ching-Hon Pui, Yiping Fan, Shondra M. Pruett-Miller, Mary V. Relling, Jun J. Yang, Chunliang Li, William E. Evans, Daniel Savic
Journal: Blood
Blood (2021) 138 (Supplement 1): 674.
https://doi.org/10.1182/blood-2021-153002
Published: 2021
Journal Articles

Regulation of Fetal Hemoglobin Expression By the VHL-HIF1α Oxygen Sensing System

Ruopeng Feng, Thiyagaraj Mayuranathan, Peng Huang, Phillip A Doerfler, Yichao Li, Yu Yao, Jingjing Zhang, Lance E. Palmer, Peng Xu, Kalin Mayberry, Shaela Wright, Chunliang Li, Yong Cheng, Gerd A. Blobel, M. Celeste Simon, Mitchell J. Weiss
Journal: Blood
Blood (2021) 138 (Supplement 1): 574.
https://doi.org/10.1182/blood-2021-149901
Published: 2021
Journal Articles

FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis

Peng Xu, Daniel C. Scott, Beisi Xu, Yu Yao, Ruopeng Feng, Li Cheng, Kalin Mayberry, Yong-Dong Wang, Wenjian Bi, Lance E. Palmer, Moeko T. King, Hong Wang, Yuxin Li, Yiping Fan, Arno F. Alpi, Chunliang Li, Junmin Peng, James Papizan, Shondra M. Pruett-Miller, Ria Spallek, Florian Bassermann, Yong Cheng, Brenda A. Schulman, Mitchell J. Weiss
Journal: Blood
Blood (2021) 137 (2): 155–167.
https://doi.org/10.1182/blood.2020007809
Published: 2021
Includes: Supplemental data
Journal Articles

Identification of New Risk Loci and Regulatory Mechanisms Influencing Genetic Susceptibility to Acute Lymphoblastic Leukaemia

Jayaram Vijayakrishnan, Maoxiang Qian, James B Studd, Wenjian Yang, Ben Kinnersley, Philip Law, Peter Broderick, Elizabeth A. Raetz, MD, James M. Allan, Ching-Hon Pui, MD, Ajay Vora, William E. Evans, PharmD, Anthony V. Moorman, Allen Eng Juh Yeoh, Chunliang Li, Claus Bartram, Charles G. Mullighan, MBBS, MD, Martin Zimmermann, Stephen P. Hunger, MD, Martin Schrappe, MD PhD, Mary V. Relling, PharmD, Martin Stanulla, Mignon L. Loh, MD, Richard S. Houlston, Jun J. Yang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 650.
https://doi.org/10.1182/blood-2019-125791
Published: 2019
Journal Articles

The DNA Methylation Maintenance Protein UHRF1 Regulates Fetal Globin Expression Independent of HBG Promoter DNA Methylation

Ruopeng Feng, PhD, Phillip A Doerfler, PhD, Yu Yao, MD, Xing Tang, PhD, Yong-Dong Wang, PhD, Chunliang Li, PhD, David E. Root, PhD, Yong Cheng, PhD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 410.
https://doi.org/10.1182/blood-2018-99-115589
Published: 2018
Journal Articles

FBXO11 Activates Erythroid Gene Transcription By Degrading Heterochromatin-Associated Protein BAHD1

Peng Xu, PhD, Daniel C. Scott, PhD, Xing Tang, PhD, Yu Yao, MD, Yong-Dong Wang, PhD, Wenjian Bi, PhD, Lance E. Palmer, PhD, Ruopeng Feng, PhD, Arno F. Alpi, PhD, Chunliang Li, PhD, Yong Cheng, PhD, Brenda A. Schulman, PhD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 529.
https://doi.org/10.1182/blood-2018-99-117362
Published: 2018
Journal Articles

Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations

Shaoyan Hu, Maoxiang Qian, Hui Zhang, Yu Guo, Jin Yang, Xujie Zhao, Hailong He, Jun Lu, Jian Pan, Meimei Chang, Guoqing Du, Ting-Nien Lin, Shirley Kow-Yin Kham, Thuan Chong Quah, Hany Ariffin, Ah-Moy Tan, Yong Cheng, Chunliang Li, Allen Eng-Juh Yeoh, Ching-Hon Pui, Anders Jacobsen Skanderup, Jun J. Yang
Journal: Blood
Blood (2017) 129 (24): 3264–3268.
https://doi.org/10.1182/blood-2017-03-771162
Published: 2017
Includes: Supplemental data
Journal Articles

Genome Editing Recreates Hereditary Persistence of Fetal Hemoglobin in Primary Human Erythroblasts

Elizabeth Traxler, Yu Yao, MD, Chunliang Li, Jeremy Grevet, Peng Huang, PhD, Shaela Wright, Gerd A. Blobel, MD PhD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2015) 126 (23): 640.
https://doi.org/10.1182/blood.V126.23.640.640
Published: 2015