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Journal Articles

Improved Outcomes for Pediatric B-ALL but Inferior Survival for T-ALL Using the Same Treatment Protocol: Results of Consecutive Malaysia-Singapore 2003 and 2010 Childhood ALL Trials

Shawn H.R. Lee, Bernice Oh, Prasad Iyer, Yiong Huat Chan, Kean Hui Chiew, Shirley Kow Yin Kham, Michaela Su-Fern Seng, Joyce CM Lam, Lee Lee Chan, Thuan Chong Quah, Hai Peng Lin, Ah Moy Tan, Hany Ariffin, Allen Eng Juh Yeoh

Blood (2024) 144 (Supplement 1): 4192.

https://doi.org/10.1182/blood-2024-193344

Published: 2024

Journal Articles

RNA Sequencing in Childhood B-Lymphoblastic Leukemia Improves Molecular and Risk Assignment

Allen Eng Juh Yeoh, MD, Zhenhua Li, PhD, Shawn Lee, MD, Winnie Hui Ni Chin, Nan Jiang, PhD, Yi Lu, PhD, Shirley Kow Yin Kham, BSc, Ah Moy Tan, MD, Hai_peng Lin, Thuan Chong Quah, Hany Ariffin, Jun J. Yang, PhD

Blood (2019) 134 (Supplement_1): 651.

https://doi.org/10.1182/blood-2019-131653

Published: 2019

Journal Articles

RNA-Seq Can Help Identify IGH Disease Clones for MRD Monitoring in Childhood B-Lymphoblastic Leukemia

Zhenhua Li, PhD, Nan Jiang, PhD, Evelyn Huizi Lim, Winnie Hui Ni Chin, Shirley Kow Yin Kham, BSc, Wentao Yang, Thuan Chong Quah, Hai_peng Lin, Ah Moy Tan, MD, Hany Ariffin, Jun J. Yang, PhD, Allen Eng Juh Yeoh, MD

Blood (2019) 134 (Supplement_1): 1471.

https://doi.org/10.1182/blood-2019-131548

Published: 2019

Journal Articles

Intensifying Treatment in Childhood B-Lymphoblastic Leukemia with IKZF1 Deletions Negates Its Adverse Outcome: Results of Ma-Spore ALL 2003 and 2010 Studies

Yi Lu, PhD, Winnie Hui Ni Chin, Evelyn Huizi Lim, Shirley Kow Yin Kham, BSc, Ah Moy Tan, MD, Hany Ariffin, MD PhD, Allen Eng Juh Yeoh, MD

Blood (2017) 130 (Supplement 1): 478.

https://doi.org/10.1182/blood.V130.Suppl_1.478.478

Published: 2017

Journal Articles

Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations

Blood (2017) 129 (24): 3264–3268.

https://doi.org/10.1182/blood-2017-03-771162

Published: 2017

Includes: Supplemental data

Journal Articles

Whole Transcriptome Sequencing Identified a Distinct Subtype of Acute Lymphoblastic Leukemia with Abnormalities of CREBBP and EP300

Blood (2016) 128 (22): 3912.

https://doi.org/10.1182/blood.V128.22.3912.3912

Published: 2016

Journal Articles

Profiling of somatic mutations in acute myeloid leukemia with FLT3 -ITD at diagnosis and relapse

Blood (2015) 126 (22): 2491–2501.

https://doi.org/10.1182/blood-2015-05-646240

Published: 2015

Includes: Supplemental data

Journal Articles

Effective Response Metric (ERM-D8) Using Time-Series Gene Expression Profiling at Diagnosis and Day 8 of Remission-Induction Therapy Is a Novel Early Prognostic Marker to Predict Relapse in Childhood Acute Lymphoblastic Leukemia (ALL) — a Malaysia-Singapore ALL Study

Allen Eng Juh Yeoh, MD, Zhenhua Li, PhD, Difeng Dong, PhD, Yi Lu, PhD, Jan Trka, MD, PhD, Prof., Shirley Kow Yin Kham, B.Sc., Ah Moy Tan, MD, Hany Ariffin, MD, Limsoon Wong, PhD

Blood (2014) 124 (21): 2393.

https://doi.org/10.1182/blood.V124.21.2393.2393

Published: 2014

Journal Articles

Genomic Profiling of Pharmacogenetic Variants Establishes a SNP-Based Predictor for Poor Outcome in Asian Children with Acute Lymphoblastic Leukemia (ALL): A Report from Malaysia-Singapore ALL Study Group

Yi Lu, PhD, Marc Hai Liang Wong, M.B.,B.S., Zhenhua Li, PhD, Shirley Kow Yin Kham, B.Sc., Ah Moy Tan, MD, Hany Ariffin, MD, Allen Eng Juh Yeoh, MD

Blood (2014) 124 (21): 1069.

https://doi.org/10.1182/blood.V124.21.1069.1069

Published: 2014

Journal Articles

Host Pharmacogenetic Factors Significantly Contribute to Refinement of Prognosis in Children with Acute Lymphoblastic Leukemia (ALL): Result From the Malaysia-Singapore (Ma-Spore) ALL 2003 Study

Yi Lu, Ph.D., Shirley Kow Yin Kham, B.Sc., Arrifin Hany, M.D., Ah Moy Tan, M.D., Thuan Chong Quah, M.D., Allen Eng Juh Yeoh, M.D.

Blood (2011) 118 (21): 567.

https://doi.org/10.1182/blood.V118.21.567.567

Published: 2011

Journal Articles

BH3-Mimetics, ABT-737 and Obatoclax, Work Synergistically to Induce Cell Death In Leukemic Cell Lines

Grace Shimin Koh, Nan Jiang, Di Feng Dong, Joshua Yew Suang Lim, Shirley Kow Yin Kham, Fook Tim Chew, Lim Soon Wong, Allen Yeoh

Blood (2010) 116 (21): 1850.

https://doi.org/10.1182/blood.V116.21.1850.1850

Published: 2010

Journal Articles

Integrated Molecular and Pharmacogenetic Profiles in Prediction of Early Response to Therapy in Children with Acute Lymphoblastic Leukemia (ALL): A Report From Malaysia-Singapore ALL Study Group.

Yi Lu, Ph.D., Shirley Kow Yin Kham, B.Sc., Hany Ariffin, M.D., Ah Moy Tan, M.D., Hai Peng Lin, M.D., Thuan Chong Quah, M.D., Allen Eng Juh Yeoh, M.D.

Blood (2009) 114 (22): 2624.

https://doi.org/10.1182/blood.V114.22.2624.2624

Published: 2009

Journal Articles

BIM Regulates Prednisolone-Induced Apoptosis in B-Lineage ALL: A Potential Biomarker.

Nan Jiang, PhD, Grace Shi Min Koh, BSc, Shirley Kow Yin Kham, BSc, Yi Lu, PhD, Fook Tim Chew, PhD, Allen Eng Juh Yeoh, MD

Blood (2008) 112 (11): 1505.

https://doi.org/10.1182/blood.V112.11.1505.1505

Published: 2008

Journal Articles

Single IGH/TCR MRD Marker Is More Informative and Cost-Effective in Risk-Stratified Therapy for Childhood ALL: Prospective Treatment Trial Results from the Malaysia-Singapore (Ma-Spore) ALL 2003 Study

Allen Eng Juh Yeoh, MD, Hany Ariffin, MD, Ah Moy Tan, MD, Thi Thu Ha Truong, BSc, Hai Peng Lin, MD, Yiong Huak Chan, PhD, Shirley Kow Yin Kham, BSc, Thuan Chong Quah, MD

Blood (2008) 112 (11): 2551.

https://doi.org/10.1182/blood.V112.11.2551.2551

Published: 2008

Journal Articles

MDR1 C3435T Polymorphism Is Highly Correlated with Early Response to Therapy and Outcome in Childhood Acute Lymphoblastic Leukaemia: Malaysia-Singapore 2003 ALL Study.

Shirley Kow Yin Kham, BSc, Hany Ariffin, MD, Yiong Huak Chan, PhD, Thuan Chong Quah, MD, Allen Eng Juh Yeoh, MD

Blood (2007) 110 (11): 226.

https://doi.org/10.1182/blood.V110.11.226.226

Published: 2007

Journal Articles

Genetic Polymorphisms in the Folate Pathway and Risk of Childhood Acute Lymphoblastic Leukemia (ALL): MTHFR, MTHFD1, RFC1 and TS.

Allen Eng-Juh Yeoh, MD, Shirley Kow-Yin Kham, BSc, Yi Lu, PhD, Toon-Chai Foo, BSc, Hany Ariffin, MD, Thuan-Chong Quah, MD

Blood (2006) 108 (11): 2274.

https://doi.org/10.1182/blood.V108.11.2274.2274

Published: 2006

Journal Articles

Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism Decreases Risk of Childhood Acute Lymphoblastic Leukemia (ALL): A Study of the Chinese and Malay Population.

Shirley Kow Yin Kham, BSc, Toon Chai Foo, Ariffin Hany, MD, Yiong Huak Chan, PhD, Hai Peng Lin, MD, Thuan Chong Quah, MD, Allen Eng Juh Yeoh, MD

Blood (2005) 106 (11): 1459.

https://doi.org/10.1182/blood.V106.11.1459.1459

Published: 2005

Journal Articles

SELDI Bone Marrow Profiling of B-Lineage Childhood Lymphoblastic Leukemia: Identity of Several Differential Markers.

Sioyong Lim, Liqun Huang, Shirley Kow Yin Kham, Fook Tim Chew, Allen Eng Juh Yeoh

Blood (2004) 104 (11): 1090.

https://doi.org/10.1182/blood.V104.11.1090.1090

Published: 2004

NARROW

Improved Outcomes for Pediatric B-ALL but Inferior Survival for T-ALL Using the Same Treatment Protocol: Results of Consecutive Malaysia-Singapore 2003 and 2010 Childhood ALL Trials

RNA Sequencing in Childhood B-Lymphoblastic Leukemia Improves Molecular and Risk Assignment

RNA-Seq Can Help Identify IGH Disease Clones for MRD Monitoring in Childhood B-Lymphoblastic Leukemia

Intensifying Treatment in Childhood B-Lymphoblastic Leukemia with IKZF1 Deletions Negates Its Adverse Outcome: Results of Ma-Spore ALL 2003 and 2010 Studies

Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations

Whole Transcriptome Sequencing Identified a Distinct Subtype of Acute Lymphoblastic Leukemia with Abnormalities of CREBBP and EP300

Profiling of somatic mutations in acute myeloid leukemia with FLT3 -ITD at diagnosis and relapse

Effective Response Metric (ERM-D8) Using Time-Series Gene Expression Profiling at Diagnosis and Day 8 of Remission-Induction Therapy Is a Novel Early Prognostic Marker to Predict Relapse in Childhood Acute Lymphoblastic Leukemia (ALL) — a Malaysia-Singapore ALL Study

Genomic Profiling of Pharmacogenetic Variants Establishes a SNP-Based Predictor for Poor Outcome in Asian Children with Acute Lymphoblastic Leukemia (ALL): A Report from Malaysia-Singapore ALL Study Group

Host Pharmacogenetic Factors Significantly Contribute to Refinement of Prognosis in Children with Acute Lymphoblastic Leukemia (ALL): Result From the Malaysia-Singapore (Ma-Spore) ALL 2003 Study

BH3-Mimetics, ABT-737 and Obatoclax, Work Synergistically to Induce Cell Death In Leukemic Cell Lines

Integrated Molecular and Pharmacogenetic Profiles in Prediction of Early Response to Therapy in Children with Acute Lymphoblastic Leukemia (ALL): A Report From Malaysia-Singapore ALL Study Group.

BIM Regulates Prednisolone-Induced Apoptosis in B-Lineage ALL: A Potential Biomarker.

Single IGH/TCR MRD Marker Is More Informative and Cost-Effective in Risk-Stratified Therapy for Childhood ALL: Prospective Treatment Trial Results from the Malaysia-Singapore (Ma-Spore) ALL 2003 Study

MDR1 C3435T Polymorphism Is Highly Correlated with Early Response to Therapy and Outcome in Childhood Acute Lymphoblastic Leukaemia: Malaysia-Singapore 2003 ALL Study.

Genetic Polymorphisms in the Folate Pathway and Risk of Childhood Acute Lymphoblastic Leukemia (ALL): MTHFR, MTHFD1, RFC1 and TS.

Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism Decreases Risk of Childhood Acute Lymphoblastic Leukemia (ALL): A Study of the Chinese and Malay Population.

SELDI Bone Marrow Profiling of B-Lineage Childhood Lymphoblastic Leukemia: Identity of Several Differential Markers.

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American Society of Hematology

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