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Maoxiang Qian
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Journal Articles

Molecular basis of ETV6 -mediated predisposition to childhood acute lymphoblastic leukemia

Rina Nishii, Rebekah Baskin-Doerfler, Wentao Yang, Ninad Oak, Xujie Zhao, Wenjian Yang, Keito Hoshitsuki, Mackenzie Bloom, Katherine Verbist, Melissa Burns, Zhenhua Li, Ting-Nien Lin, Maoxiang Qian, Takaya Moriyama, Julie M. Gastier-Foster, Karen R. Rabin, Elizabeth Raetz, Charles Mullighan, Ching-Hon Pui, Allen Eng-Juh Yeoh, Jinghui Zhang, Monika L. Metzger, Jeffery M. Klco, Stephen P. Hunger, Scott Newman, Gang Wu, Mignon L. Loh, Kim E. Nichols, Jun J. Yang
Journal: Blood
Blood (2021) 137 (3): 364–373.
https://doi.org/10.1182/blood.2020006164
Published: 2021
Includes: Supplemental data
Journal Articles

Identification of New Risk Loci and Regulatory Mechanisms Influencing Genetic Susceptibility to Acute Lymphoblastic Leukaemia

Jayaram Vijayakrishnan, Maoxiang Qian, James B Studd, Wenjian Yang, Ben Kinnersley, Philip Law, Peter Broderick, Elizabeth A. Raetz, MD, James M. Allan, Ching-Hon Pui, MD, Ajay Vora, William E. Evans, PharmD, Anthony V. Moorman, Allen Eng Juh Yeoh, Chunliang Li, Claus Bartram, Charles G. Mullighan, MBBS, MD, Martin Zimmermann, Stephen P. Hunger, MD, Martin Schrappe, MD PhD, Mary V. Relling, PharmD, Martin Stanulla, Mignon L. Loh, MD, Richard S. Houlston, Jun J. Yang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 650.
https://doi.org/10.1182/blood-2019-125791
Published: 2019
Journal Articles

Germline RUNX1 Variation and Predisposition to T-Cell Acute Lymphoblastic Leukemia in Children

Yizhen Li, PhD, Maoxiang Qian, Meenakshi Devidas, PhD, Wentao Yang, PhD, Stuart S. Winter, MD, Kimberly P. Dunsmore, Colton A Smith, Ting-Nien Lin, Xuijie Zhao, Ranran Zhang, Julie M. Gastier Foster, Elizabeth A. Raetz, MD, William L. Carroll, MD, Karen R. Rabin, MD PhD, Wenjian Yang, Patrick A. Zweidler-McKay, MD PhD, Ching-Hon Pui, MD, William E. Evans, PharmD, Charles G. Mullighan, MBBS, MD, Stephen P. Hunger, MD, Mary V. Relling, PharmD, Mignon L. Loh, MD, Jun J. Yang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 653.
https://doi.org/10.1182/blood-2019-125912
Published: 2019
Journal Articles

Novel susceptibility variants at the ERG locus for childhood acute lymphoblastic leukemia in Hispanics

Brief Report
Maoxiang Qian, Heng Xu, Virginia Perez-Andreu, Kathryn G. Roberts, Hui Zhang, Wenjian Yang, Shouyue Zhang, Xujie Zhao, Colton Smith, Meenakshi Devidas, Julie M. Gastier-Foster, Elizabeth Raetz, Eric Larsen, Esteban G. Burchard, Naomi Winick, W. Paul Bowman, Paul L. Martin, Michael Borowitz, Brent Wood, Federico Antillon-Klussmann, Ching-Hon Pui, Charles G. Mullighan, William E. Evans, Stephen P. Hunger, Mary V. Relling, Mignon L. Loh, Jun J. Yang
Journal: Blood
Blood (2019) 133 (7): 724–729.
https://doi.org/10.1182/blood-2018-07-862946
Published: 2019
Includes: Supplemental data
Journal Articles

PDGFRB mutation and tyrosine kinase inhibitor resistance in Ph-like acute lymphoblastic leukemia

CME Brief Report
Yingchi Zhang, Yufeng Gao, Hui Zhang, Jingliao Zhang, Fuhong He, Aleš Hnízda, Maoxiang Qian, Xiaoming Liu, Yoshihiro Gocho, Ching-Hon Pui, Tao Cheng, Qianfei Wang, Jun J. Yang, Xiaofan Zhu, Xin Liu
Journal: Blood
Blood (2018) 131 (20): 2256–2261.
https://doi.org/10.1182/blood-2017-11-817510
Published: 2018
Includes: Supplemental data
Journal Articles

TP53 Germline Variations Influence the Predisposition and Prognosis of Acute Lymphoblastic Leukemia in Children

Maoxiang Qian, PhD, Xueyuan Cao, PhD, Meenakshi Devidas, PhD, Wenjian Yang, PhD, Cheng Cheng, PhD, Andrew Carroll, PhD, Nyla A. Heerema, PhD, Hui Zhang, PhD MD, Takaya Moriyama, MDPhD, Julie M. Gastier-Foster, PhD, Heng Xu, PhD, Elizabeth A. Raetz, MD, Eric Larsen, MD, Naomi Winick, MD, W. Paul Bowman, MD, Paul L. Martin, MD PhD, Elaine R. Mardis, PhD, Robert Fulton, MS, Gerard Zambetti, PhD, Michael Borowitz, MD PhD, Brent Wood, MDPhD, Kim E. Nichols, MD, William L. Carroll, MD, Ching-Hon Pui, MD, Charles G. Mullighan, MBBS, MD, William E. Evans, PharmD, Stephen P. Hunger, MD, Mary V. Relling, PharmD, Mignon L. Loh, MD, Jun J. Yang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 31.
https://doi.org/10.1182/blood.V130.Suppl_1.31.31
Published: 2017
Journal Articles

GATA3 rs3824662A Allele Is Overrepresented in Adult Patients with Ph-like ALL, Especially in Patients with CRLF2 Abnormalities

Nitin Jain, MD, Hui Zhang, PhD MD, Kathryn G. Roberts, PhD, Maoxiang Qian, PhD, Wenjian Yang, PhD, Elias J. Jabbour, MD, Hagop M. Kantarjian, MD, Charles G. Mullighan, MBBS, MD, Jun J. Yang, PhD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1430.
https://doi.org/10.1182/blood.V130.Suppl_1.1430.1430
Published: 2017
Journal Articles

Characterization of Causal Variants at the GATA3 Loci Associated with Susceptibility to Ph-like Acute Lymphoblastic Leukemia

Hui Zhang, PhD MD, Hongbo Yang, PhD, Tingting Liu, PhD, Maoxiang Qian, PhD, Wenjian Yang, PhD, Kathryn G. Roberts, PhD, Virginia Perez-Andreu, MD PhD, Heng Xu, PhD, Julie M. Gastier-Foster, PhD, Colton Smith, PhD, Ching-Hon Pui, MD, William E. Evans, PharmD, Mary V. Relling, PharmD, Stephen P. Hunger, MD, Charles G. Mullighan, MBBS, MD, Mignon L. Loh, MD, Feng Yue, PhD, Jun J. Yang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 475.
https://doi.org/10.1182/blood.V130.Suppl_1.475.475
Published: 2017
Journal Articles

Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations

Shaoyan Hu, Maoxiang Qian, Hui Zhang, Yu Guo, Jin Yang, Xujie Zhao, Hailong He, Jun Lu, Jian Pan, Meimei Chang, Guoqing Du, Ting-Nien Lin, Shirley Kow-Yin Kham, Thuan Chong Quah, Hany Ariffin, Ah-Moy Tan, Yong Cheng, Chunliang Li, Allen Eng-Juh Yeoh, Ching-Hon Pui, Anders Jacobsen Skanderup, Jun J. Yang
Journal: Blood
Blood (2017) 129 (24): 3264–3268.
https://doi.org/10.1182/blood-2017-03-771162
Published: 2017
Includes: Supplemental data
Journal Articles

Germline Genetic Variation in IKZF1 and Predisposition to Childhood Acute Lymphoblastic Leukemia

Michelle L. Churchman, PhD, Maoxiang Qian, PhD, Ranran Zhang, MD, Geertruy Kronnie, PhD, Wenjian Yang, PhD, Hui Zhang, MD, PhD, Tobia Lana, Paige Tedrick, Rebekah Baskin, PhD, Katherine Verbist, PhD, Meenakshi Devidas, PhD, Elizabeth Raetz, MD, Eric Larsen, MD, Paul L. Martin, MD PhD, W. Paul Bowman, Naomi Winick, MD, Elaine R Mardis, PhD, Robert S. Fulton, PhD, Martin Stanulla, MD, William E. Evans, PharmD, Mary V. Relling, PharmD, Ching-Hon Pui, MD, Rupert Handgretinger, MD, Stephen P. Hunger, Mignon L. Loh, MD, Kim E. Nichols, MD, Charles Mullighan, MBBS, MSc, MD, Jun J. Yang, PhD
Journal: Blood
Blood (2016) 128 (22): LBA-2.
https://doi.org/10.1182/blood.V128.22.LBA-2.LBA-2
Published: 2016
Journal Articles

Whole Transcriptome Sequencing Identified a Distinct Subtype of Acute Lymphoblastic Leukemia with Abnormalities of CREBBP and EP300

Hui Zhang, MD, PhD, Maoxiang Qian, PhD, Shirley, Kow Yin Kham, MD, PhD, Shuguang Liu, PhD, Chuang Jiang, BS, Xujie Zhao, MS, Yi Lu, PhD, Ting-Nien Lin, Pharma D, Ranran Zhang, MD, Takaya Moriyama, MD PhD, Zhaohong Yin, MD, PhD, Lei Shi, PhD, Zhenhua Li, MD, Kean-Hui Chiew, MD, Zhiwei Chen, MD, Bhojwani Deepa, MD, Shuhong Shen, MD, PhD, Huyong Zheng, MD PhD, Ching-Hon Pui, MD, Allen Eng Juh Yeoh, MD, Jun J. Yang, PhD
Journal: Blood
Blood (2016) 128 (22): 3912.
https://doi.org/10.1182/blood.V128.22.3912.3912
Published: 2016
Journal Articles

Germline Genetic Variation in ETV6 and Predisposition to Childhood Acute Lymphoblastic Leukemia

Takaya Moriyama, MD, Monika Metzger, MD, Gang Wu, PhD, Rina Nishii, Maoxiang Qian, PhD, Meenakshi Devidas, PhD, Wenjian Yang, PhD, Emily Quinn, MS, Julie Gastier-Foster, PhD, Elizabeth Raetz, MD, Eric C. Larsen, MD, Paul L. Martin, MD PhD, W. Paul Bowman, MD, Naomi J. Winick, MD, Yoshihiro Komada, MD PhD, Elaine R Mardis, PhD, Robert Fulton, PhD, Ching-Hon Pui, MD, William E. Evans, PharmD, Jinghui Zhang, PhD, Stephen P Hunger, MD, Mary V. Relling, PharmD, Kim E Nichols, MD, Mignon Loh, MD, Jun J Yang, PhD
Journal: Blood
Blood (2015) 126 (23): 695.
https://doi.org/10.1182/blood.V126.23.695.695
Published: 2015
Journal Articles

ARID5B Regulates Leukemia Sensitivity to Antimetabolites in Children with Acute Lymphoblastic Leukemia Via Effects on Cell Cycle Progression

Jun J. Yang, PhD, Heng Xu, PhD, Deepa Bhojwani, Takaya Moriyama, MD, Maoxiang Qian, PhD, Xue Yang, Nita L. Seibel, MD, Mary V. Relling, PharmD, William L. Carroll, MD, Ching-Hon Pui, MD, William E. Evans, PharmD
Journal: Blood
Blood (2014) 124 (21): 791.
https://doi.org/10.1182/blood.V124.21.791.791
Published: 2014