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Journal Articles

NKTR-255 Vs Placebo to Enhance Complete Responses and Durability Following CD19-Directed CAR-T Therapy in Patients with Relapsed/ Refractory (R/R) Large B-Cell Lymphoma (LBCL)

Sairah Ahmed, John F. DiPersio, James H Essell, Catherine S. Diefenbach, Miguel Angel Perales, Cristina Castilla-Llorente, Saurabh Dahiya, Sohail Chaudhry, Heng Xu, Yi Liu, Christie Fanton, Zachary Lee, Mario Q. Marcondes, Mary Tagliaferri, Jonathan Zalevsky, David B. Miklos, Cameron J. Turtle, Joseph P. McGuirk
Journal: Blood
Blood (2024) 144 (Supplement 1): 2068.
https://doi.org/10.1182/blood-2024-203576
Published: 2024
Journal Articles

Safety, Tolerability, PK/PD and Preliminary Efficacy of NKTR-255, a Novel IL-15 Receptor Agonist, in Patients with Relapsed/Refractory Hematologic Malignancies

Krina Patel, Nina Shah, Alan Tan, Andrew J Cowan, Cameron J. Turtle, Craig C Hofmeister, Taewoong Choi, Hayder Saeed, Julio C. Chavez, Matthew J. Pianko, Mitul Gandhi, Sohail A. Chaudhry, Zachary Lee, Neha Dixit, Christie Fanton, Xiaoli Wang, Heng Xu, Mario Q. Marcondes, Mary A. Tagliaferri, Jonathan Zalevsky, Miguel-Angel Perales
Journal: Blood
Blood (2022) 140 (Supplement 1): 10357–10359.
https://doi.org/10.1182/blood-2022-162539
Published: 2022
Journal Articles

Novel susceptibility variants at the ERG locus for childhood acute lymphoblastic leukemia in Hispanics

Brief Report
Maoxiang Qian, Heng Xu, Virginia Perez-Andreu, Kathryn G. Roberts, Hui Zhang, Wenjian Yang, Shouyue Zhang, Xujie Zhao, Colton Smith, Meenakshi Devidas, Julie M. Gastier-Foster, Elizabeth Raetz, Eric Larsen, Esteban G. Burchard, Naomi Winick, W. Paul Bowman, Paul L. Martin, Michael Borowitz, Brent Wood, Federico Antillon-Klussmann, Ching-Hon Pui, Charles G. Mullighan, William E. Evans, Stephen P. Hunger, Mary V. Relling, Mignon L. Loh, Jun J. Yang
Journal: Blood
Blood (2019) 133 (7): 724–729.
https://doi.org/10.1182/blood-2018-07-862946
Published: 2019
Includes: Supplemental data
Journal Articles

Leukemia Risk Gene ARID5B is a Crucial Regulator of B-Cell Development

Charnise Goodings-Harris, PhD, Hui Zhang, PhD, Xuijie Zhao, Heng Xu, PhD, Omar I Abdel-Wahab, MD, Shannon McKinney-Freeman, PhD, Jun J. Yang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 385.
https://doi.org/10.1182/blood-2018-99-113686
Published: 2018
Journal Articles

Characterization of Causal Variants at the GATA3 Loci Associated with Susceptibility to Ph-like Acute Lymphoblastic Leukemia

Hui Zhang, PhD MD, Hongbo Yang, PhD, Tingting Liu, PhD, Maoxiang Qian, PhD, Wenjian Yang, PhD, Kathryn G. Roberts, PhD, Virginia Perez-Andreu, MD PhD, Heng Xu, PhD, Julie M. Gastier-Foster, PhD, Colton Smith, PhD, Ching-Hon Pui, MD, William E. Evans, PharmD, Mary V. Relling, PharmD, Stephen P. Hunger, MD, Charles G. Mullighan, MBBS, MD, Mignon L. Loh, MD, Feng Yue, PhD, Jun J. Yang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 475.
https://doi.org/10.1182/blood.V130.Suppl_1.475.475
Published: 2017
Journal Articles

TP53 Germline Variations Influence the Predisposition and Prognosis of Acute Lymphoblastic Leukemia in Children

Maoxiang Qian, PhD, Xueyuan Cao, PhD, Meenakshi Devidas, PhD, Wenjian Yang, PhD, Cheng Cheng, PhD, Andrew Carroll, PhD, Nyla A. Heerema, PhD, Hui Zhang, PhD MD, Takaya Moriyama, MDPhD, Julie M. Gastier-Foster, PhD, Heng Xu, PhD, Elizabeth A. Raetz, MD, Eric Larsen, MD, Naomi Winick, MD, W. Paul Bowman, MD, Paul L. Martin, MD PhD, Elaine R. Mardis, PhD, Robert Fulton, MS, Gerard Zambetti, PhD, Michael Borowitz, MD PhD, Brent Wood, MDPhD, Kim E. Nichols, MD, William L. Carroll, MD, Ching-Hon Pui, MD, Charles G. Mullighan, MBBS, MD, William E. Evans, PharmD, Stephen P. Hunger, MD, Mary V. Relling, PharmD, Mignon L. Loh, MD, Jun J. Yang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 31.
https://doi.org/10.1182/blood.V130.Suppl_1.31.31
Published: 2017
Journal Articles

A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults

Clinical Trials & Observations
Virginia Perez-Andreu, Kathryn G. Roberts, Heng Xu, Colton Smith, Hui Zhang, Wenjian Yang, Richard C. Harvey, Debbie Payne-Turner, Meenakshi Devidas, I-Ming Cheng, William L. Carroll, Nyla A. Heerema, Andrew J. Carroll, Elizabeth A. Raetz, Julie M. Gastier-Foster, Guido Marcucci, Clara D. Bloomfield, Krzysztof Mrózek, Jessica Kohlschmidt, Wendy Stock, Steven M. Kornblau, Marina Konopleva, Elisabeth Paietta, Jacob M. Rowe, Selina M. Luger, Martin S. Tallman, Michael Dean, Esteban G. Burchard, Dara G. Torgerson, Feng Yue, Yanli Wang, Ching-Hon Pui, Sima Jeha, Mary V. Relling, William E. Evans, Daniela S. Gerhard, Mignon L. Loh, Cheryl L. Willman, Stephen P. Hunger, Charles G. Mullighan, Jun J. Yang
Journal: Blood
Blood (2015) 125 (4): 680–686.
https://doi.org/10.1182/blood-2014-09-595744
Published: 2015
Includes: Supplemental data
Journal Articles

ARID5B Regulates Leukemia Sensitivity to Antimetabolites in Children with Acute Lymphoblastic Leukemia Via Effects on Cell Cycle Progression

Jun J. Yang, PhD, Heng Xu, PhD, Deepa Bhojwani, Takaya Moriyama, MD, Maoxiang Qian, PhD, Xue Yang, Nita L. Seibel, MD, Mary V. Relling, PharmD, William L. Carroll, MD, Ching-Hon Pui, MD, William E. Evans, PharmD
Journal: Blood
Blood (2014) 124 (21): 791.
https://doi.org/10.1182/blood.V124.21.791.791
Published: 2014
Journal Articles

Inherited GATA3 genetic Variants Are Associated With Childhood BCR-ABL1 -Like Acute Lymphoblastic Leukemia and Increased Risk Of Relapse

Virginia Perez-Andreu, MD PhD, Kathryn G. Roberts, PhD, Richard C. Harvey, PhD, Wenjian Yang, PhD, Cheng Cheng, PhD, Deqing Pei, MS, Heng Xu, PhD, Julie Gastier-Fostier, PhD, Shuyu E, PhD, Joshua Yew-Suang Lim, I-Ming L. Chen, Yiping Fan, PhD, Meenakshi Devidas, PhD, Michael J. Borowitz, MD, PhD, Colton Smith, PhD, Geoffrey A. Neale, PhD, Esteban Gonzalez Burchard, MD, MPH, Dara G Torgerson, PhD, Federico Antillon, MD, Cesar Rolando, B.S., Naomi J. Winick, MD, Bruce Camitta, MD, Elizabeth A. Raetz, MD, Brent L. Wood, MD, PhD, Feng Yue, PhD, William L. Carroll, MD, Eric C. Larsen, MD, William Paul Bowman, MD, Mignon L. Loh, MD, Michael Dean, PhD, Deepa Bhojwani, MD, Ching-Hon Pui, MD, William E. Evans, PharmD, Mary V. Relling, PharmD, Stephen P. Hunger, MD, Cheryl L. Willman, MD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA, Jun J. Yang, PhD
Journal: Blood
Blood (2013) 122 (21): 617.
https://doi.org/10.1182/blood.V122.21.617.617
Published: 2013
Journal Articles

PDE4B Modulates Glucocorticoid Sensitivity in Childhood Acute Lymphoblastic Leukemia

Jun J. Yang, PhD, Shuyu E, PhD, Shuhong Shen, MD, PhD, Deepa Bhojwani, MD, Huining Kang, PhD, Yani Ma, PhD, Jing Chen, MD, PhD, JingYan Tang, MD, Nita L. Seibel, MD, Heng Xu, PhD, Jin Cheng, Laura B. Ramsey, PhD, Kristine Crews, PharmD, W. Paul Bowman, MD, Michael J. Borowitz, MD, PhD, William L. Carroll, MD, Cheryl L. Willman, MD, Sima Jeha, MD, Ching-Hon Pui, MD, Stephen P. Hunger, MD, Mary V. Relling, PharmD, William E. Evans, PharmD
Journal: Blood
Blood (2012) 120 (21): 530.
https://doi.org/10.1182/blood.V120.21.530.530
Published: 2012
Journal Articles

Genome-Wide Association Study Identifies a Novel Susceptibility Locus At 10p12.31-12.2 for Childhood Acute Lymphoblastic Leukemia in Ethinically Diverse Populations

Jun J. Yang, PhD, Heng Xu, PhD, Wenjian Yang, PhD, Virginia Perez-Andreu, PhD, Meenakshi Devidas, PhD, Yiping Fan, PhD, Cheng Cheng, PhD, Deqing Pei, MS, Paul Scheet, PhD, Esteban Gonzalez Burchard, MD, MPH, Celeste Eng, BS, Scott Huntsman, MS, Dara G Torgerson, PhD, Michael Dean, PhD, Naomi Winick, MD, Paul L. Martin, MD, PhD, Bruce Camitta, MD, W. Paul Bowman, MD, Cheryl L Willman, MD, William L. Carroll, MD, Charles G Mullighan, MBBS, MD, FRACP, FRCPA, MSc, Deepa Bhojwani, MD, Stephen P. Hunger, MD, Ching-Hon Pui, MD, William E. Evans, PharmD, Mary V. Relling, PharmD, Mignon L. Loh, MD
Journal: Blood
Blood (2012) 120 (21): 877.
https://doi.org/10.1182/blood.V120.21.877.877
Published: 2012
Journal Articles

ARID5B Genetic Polymorphisms Contribute to Racial Disparities In Childhood Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

Jun Yang, PhD, Heng Xu, PhD, Cheng Cheng, Ph.D., Meenakshi Devidas, PhD, Deqing Pei, Yiping Fan, PhD, Wenjian Yang, PhD, Geoffrey A. Neale, PhD, Naomi J. Winick, MD, Paul L Martin, MD, PhD, Cheryl L. Willman, MD, Bruce M. Camitta, MD, Gregory H. Reaman, PhD, William L. Carroll, PhD, Mignon Loh, MD, Stephen P. Hunger, MD, William E. Evans, PharmD, Mary V. Relling, PharmD
Journal: Blood
Blood (2010) 116 (21): 8.
https://doi.org/10.1182/blood.V116.21.8.8
Published: 2010