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Journal Articles

Safety and Efficacy of Olverembatinib (HQP1351) Combined with Lisaftoclax (APG-2575) in Children and Adolescents with Relapsed/Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (R/R Ph + ALL): First Report from a Phase 1 Study

Jingliao Zhang, Junxia Wang, Huanshan Guo, Tianfeng Liu, Xiaoyan Zhang, Ranran Zhang, Min Ruan, Lixian Chang, Xiaoming Liu, Yuanyuan Ren, Xia Chen, Hengbang Wang, Zi Chen, Yingchi Zhang, Yumei Chen, Li Zhang, Ye Guo, Fang Liu, Xiaojuan Chen, Yao Zou, Wenyu Yang, Yifan Zhai, Xiaofan Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1443.
https://doi.org/10.1182/blood-2024-207035
Published: 2024
Journal Articles

Trp53 -Loss in Hematopoietic Stem Cells Drives the Evolutionary Process of Leukemic Transformation in a Jak2 V617F -Driven Myeloproliferative Neoplasms Mouse Model

Ranran Zhang, Yashaswini Janardhanan, Rohit Haldar, Leanne Cooper, Sebastien Jaquelin, Jasmin Straube, Megan Bywater, Steven W Lane
Journal: Blood
Blood (2023) 142 (Supplement 1): 4522.
https://doi.org/10.1182/blood-2023-188150
Published: 2023
Journal Articles

Acetyl Transferase EP300 Deficiency Leads to Chronic Replication Stress in Adult T-Cell Leukemia/Lymphoma

Mrunmai Niljikar, Aastha Juwarwala, Julia Gagliardi, Ranran Zhang, B. Hilda Ye, Advaitha Madireddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 1404.
https://doi.org/10.1182/blood-2023-187061
Published: 2023
Journal Articles

Clinical Feature and Effect of Demethylation Therapy in Pediatric Patients with Acute Myeloid Leukemia with Myelodysplasia-Related Changes

Yang Wan, Ranran Zhang, Min Ruan, Jun Li, Xiaolan Li, Xiaoyan Zhang, Xiaojuan Chen, Li Zhang, Yao Zou, Yumei Chen, Ye Guo, Wenyu Yang, Xiaofan Zhu
Journal: Blood
Blood (2022) 140 (Supplement 1): 11628–11629.
https://doi.org/10.1182/blood-2022-168436
Published: 2022
Journal Articles

Germline RUNX1 Variation and Predisposition to T-Cell Acute Lymphoblastic Leukemia in Children

Yizhen Li, PhD, Maoxiang Qian, Meenakshi Devidas, PhD, Wentao Yang, PhD, Stuart S. Winter, MD, Kimberly P. Dunsmore, Colton A Smith, Ting-Nien Lin, Xuijie Zhao, Ranran Zhang, Julie M. Gastier Foster, Elizabeth A. Raetz, MD, William L. Carroll, MD, Karen R. Rabin, MD PhD, Wenjian Yang, Patrick A. Zweidler-McKay, MD PhD, Ching-Hon Pui, MD, William E. Evans, PharmD, Charles G. Mullighan, MBBS, MD, Stephen P. Hunger, MD, Mary V. Relling, PharmD, Mignon L. Loh, MD, Jun J. Yang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 653.
https://doi.org/10.1182/blood-2019-125912
Published: 2019
Journal Articles

Chemosensitizing Effect of Fenretinide-Induced NF-κb Inhibition in AML Therapy

Ranran Zhang, MD, Wei Fenggui, MD, Ru Chen, MD, Ming Liang, MD, Liping Wu, MD, Hui Zhang, MD, PhD, Fuxiong Chen, MD
Journal: Blood
Blood (2016) 128 (22): 1580.
https://doi.org/10.1182/blood.V128.22.1580.1580
Published: 2016
Journal Articles

Germline Genetic Variation in IKZF1 and Predisposition to Childhood Acute Lymphoblastic Leukemia

Michelle L. Churchman, PhD, Maoxiang Qian, PhD, Ranran Zhang, MD, Geertruy Kronnie, PhD, Wenjian Yang, PhD, Hui Zhang, MD, PhD, Tobia Lana, Paige Tedrick, Rebekah Baskin, PhD, Katherine Verbist, PhD, Meenakshi Devidas, PhD, Elizabeth Raetz, MD, Eric Larsen, MD, Paul L. Martin, MD PhD, W. Paul Bowman, Naomi Winick, MD, Elaine R Mardis, PhD, Robert S. Fulton, PhD, Martin Stanulla, MD, William E. Evans, PharmD, Mary V. Relling, PharmD, Ching-Hon Pui, MD, Rupert Handgretinger, MD, Stephen P. Hunger, Mignon L. Loh, MD, Kim E. Nichols, MD, Charles Mullighan, MBBS, MSc, MD, Jun J. Yang, PhD
Journal: Blood
Blood (2016) 128 (22): LBA-2.
https://doi.org/10.1182/blood.V128.22.LBA-2.LBA-2
Published: 2016
Journal Articles

Whole Transcriptome Sequencing Identified a Distinct Subtype of Acute Lymphoblastic Leukemia with Abnormalities of CREBBP and EP300

Hui Zhang, MD, PhD, Maoxiang Qian, PhD, Shirley, Kow Yin Kham, MD, PhD, Shuguang Liu, PhD, Chuang Jiang, BS, Xujie Zhao, MS, Yi Lu, PhD, Ting-Nien Lin, Pharma D, Ranran Zhang, MD, Takaya Moriyama, MD PhD, Zhaohong Yin, MD, PhD, Lei Shi, PhD, Zhenhua Li, MD, Kean-Hui Chiew, MD, Zhiwei Chen, MD, Bhojwani Deepa, MD, Shuhong Shen, MD, PhD, Huyong Zheng, MD PhD, Ching-Hon Pui, MD, Allen Eng Juh Yeoh, MD, Jun J. Yang, PhD
Journal: Blood
Blood (2016) 128 (22): 3912.
https://doi.org/10.1182/blood.V128.22.3912.3912
Published: 2016
Journal Articles

Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia

Xin Liu, Lindsay Ryland, Jun Yang, Aijun Liao, Cesar Aliaga, Rebecca Watts, Su-Fern Tan, James Kaiser, Sriram S. Shanmugavelandy, Andrew Rogers, Kathleen Loughran, Bailey Petersen, Jonathan Yuen, Fanxue Meng, Kendall Thomas Baab, Nancy Ruth Jarbadan, Kathleen Broeg, Ranran Zhang, Jason Liao, Thomas Joseph Sayers, Mark Kester, Thomas P. Loughran, Jr
Journal: Blood
Blood (2010) 116 (20): 4192–4201.
https://doi.org/10.1182/blood-2010-02-271080
Published: 2010
Journal Articles

Platelet-derived growth factor mediates survival of leukemic large granular lymphocytes via an autocrine regulatory pathway

Jun Yang, Xin Liu, Susan B. Nyland, Ranran Zhang, Lindsay K. Ryland, Kathleen Broeg, Kendall Thomas Baab, Nancy Ruth Jarbadan, Rosalyn Irby, Thomas P. Loughran, Jr
Journal: Blood
Blood (2010) 115 (1): 51–60.
https://doi.org/10.1182/blood-2009-06-223719
Published: 2010
Includes: Supplemental data
Journal Articles

Systemic Delivery of Nanoliposomal Ceramide Displays Anti-Leukemic Activity in a Rat Model of Large Granular Lymphocytic Leukemia

Xin Liu, M.D., Ph.D., Lindsay Ryland, Jun Yang, M.D., Cesar Aliaga, James Kaiser, Ranran Zhang, Kendall Thomas, Ruth Nancy Jarbadan, Joseph Hughes, Mark Kester, Ph.D., Thomas P. Loughran, Jr., M.D.
Journal: Blood
Blood (2008) 112 (11): 3999.
https://doi.org/10.1182/blood.V112.11.3999.3999
Published: 2008
Journal Articles

Platelet-Derived Growth Factor (PDGF)-BB Mediates Survival of Leukemic Large Granular Lymphocyte Via An Autocrine Regulatory Pathway

Jun Yang, M.D., Xin Liu, M.D., Ph.D., Susan Nyland, Ph.D., Ranran Zhang, Kendall Thomas, Ruth Nancy Jarbadan, Thomas P. Loughran, Jr., M.D.
Journal: Blood
Blood (2008) 112 (11): 3803.
https://doi.org/10.1182/blood.V112.11.3803.3803
Published: 2008
Journal Articles

Molecular profiling of LGL leukemia reveals role of sphingolipid signaling in survival of cytotoxic lymphocytes

Mithun Vinod Shah, Ranran Zhang, Rosalyn Irby, Ravi Kothapalli, Xin Liu, Ty Arrington, Bryan Frank, Norman H. Lee, Thomas P. Loughran, Jr
Journal: Blood
Blood (2008) 112 (3): 770–781.
https://doi.org/10.1182/blood-2007-11-121871
Published: 2008
Includes: Supplemental data