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Huanshan Guo
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Journal Articles

Olverembatinib (HQP1351) Overcomes Resistance/Intolerance to Asciminib and Ponatinib in Patients (pts) with Heavily Pretreated Chronic-Phase Chronic Myeloid Leukemia (CP-CML): A 1.5-Year Follow-up Update with Comprehensive Exposure-Response (E-R) Analyses

Elias Jabbour, Omer Jamy, Paul B. Koller, Vivian G. Oehler, Maria R. Baer, Elza Lomaia, Anthony M. Hunter, Olga Uspenskaya, Svetlana Samarina, Jorge E. Cortes, Sudipto Mukherjee, Dennis Dong Hwan Kim, Vera Zherebtsova, Vasily Shuvaev, Anna Turkina, Igor Davydkin, Huanshan Guo, Zi Chen, Hengbang Wang, Tommy Fu, Lixin Jiang, Zhihong Yang, Cunlin Wang, Dajun Yang, Yifan Zhai, Hagop Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 3151.
https://doi.org/10.1182/blood-2024-207139
Published: 2024
Journal Articles

Safety and Efficacy of Olverembatinib (HQP1351) Combined with Lisaftoclax (APG-2575) in Children and Adolescents with Relapsed/Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (R/R Ph + ALL): First Report from a Phase 1 Study

Jingliao Zhang, Junxia Wang, Huanshan Guo, Tianfeng Liu, Xiaoyan Zhang, Ranran Zhang, Min Ruan, Lixian Chang, Xiaoming Liu, Yuanyuan Ren, Xia Chen, Hengbang Wang, Zi Chen, Yingchi Zhang, Yumei Chen, Li Zhang, Ye Guo, Fang Liu, Xiaojuan Chen, Yao Zou, Wenyu Yang, Yifan Zhai, Xiaofan Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1443.
https://doi.org/10.1182/blood-2024-207035
Published: 2024
Journal Articles

Embryonic Ectoderm Development (EED) Inhibitor APG-5918 Demonstrates Robust Antitumor Activity in Preclinical Models of T-Cell Lymphomas (TCLs)

Zhiyan Liang, Yan Yin, Huanshan Guo, Baisong Li, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2024) 144 (Supplement 1): 1415.
https://doi.org/10.1182/blood-2024-202655
Published: 2024
Journal Articles

Lisaftoclax (APG-2575) Combined with Novel Therapeutic Regimens in Patients (pts) with Relapsed or Refractory Multiple Myeloma (R/R MM) or Immunoglobulin Light-Chain (AL) Amyloidosis

Sikander Ailawadhi, Asher A. Chanan-Khan, Jack Khouri, Costas K. Yannakou, Zi Chen, Yanyan Wang, Huanshan Guo, Hengbang Wang, Mingyu Li, Mohammad Ahmad, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2024) 144 (Supplement 1): 1022.
https://doi.org/10.1182/blood-2024-202713
Published: 2024
Journal Articles

First Report on the Effects of Lisaftoclax (APG-2575) in Combination with Novel Therapeutic Regimens in Patients with Relapsed or Refractory Multiple Myeloma (R/R MM) or Immunoglobulin Light-Chain (Amyloid Light-Chain [AL]) Amyloidosis

Sikander Ailawadhi, Asher A. Chanan-Khan, Costas K. Yannakou, Simon Gibbs, Jack Khouri, Zi Chen, Huanshan Guo, Mingyu Li, Mohammad Ahmad, Cunlin Wang, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2023) 142 (Supplement 1): 2016.
https://doi.org/10.1182/blood-2023-188122
Published: 2023
Journal Articles

Update of Olverembatinib (HQP1351) Overcoming Ponatinib and/or Asciminib Resistance in Patients (Pts) with Heavily Pretreated/Refractory Chronic Myeloid Leukemia (CML) and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph + ALL)

Elias Jabbour, Hagop M. Kantarjian, Paul B. Koller, Omer Jamy, Vivian G. Oehler, Elza Lomaia, Anthony M. Hunter, Olga Uspenskaya, Svetlana Samarina, Sudipto Mukherjee, Maria R. Baer, Vera Zherebtsova, Vasily Shuvaev, Anna Turkina, Igor Davydkin, Jorge Cortes, Huanshan Guo, Zi Chen, Lei Fu, Hengbang Wang, Lixin Jiang, Cunlin Wang, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2023) 142 (Supplement 1): 1798.
https://doi.org/10.1182/blood-2023-187744
Published: 2023
Journal Articles

Olverembatinib (HQP1351) Overcomes Ponatinib Resistance in Patients with Heavily Pretreated/Refractory Chronic Myeloid Leukemia (CML) and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Elias Jabbour, Paul B. Koller, Vivian G. Oehler, Omer H Jamy, Sudipto Mukherjee, Anthony M. Hunter, Maria R. Baer, Joseph T. Beck, Zi Chen, Huanshan Guo, Lei Fu, Lichuang Men, Hengbang Wang, Dajun Yang, Yifan Zhai, Hagop Kantarjian, Lixin Jiang, Cunlin Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 200–202.
https://doi.org/10.1182/blood-2022-162387
Published: 2022