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Mohammad Ahmad
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Journal Articles

Lisaftoclax (APG-2575) Combined with Novel Therapeutic Regimens in Patients (pts) with Relapsed or Refractory Multiple Myeloma (R/R MM) or Immunoglobulin Light-Chain (AL) Amyloidosis

Sikander Ailawadhi, Asher A. Chanan-Khan, Jack Khouri, Costas K. Yannakou, Zi Chen, Yanyan Wang, Huanshan Guo, Hengbang Wang, Mingyu Li, Mohammad Ahmad, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2024) 144 (Supplement 1): 1022.
https://doi.org/10.1182/blood-2024-202713
Published: 2024
Journal Articles

Lisaftoclax (APG-2575) Demonstrates Activity and Safety When Given with Accelerated Ramp-up and then Combined with Acalabrutinib or Rituximab in Patients (pts) with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Including Those with Prior Exposure to Venetoclax

Matthew S. Davids, Sikander Ailawadhi, Asher A. Chanan-Khan, Boyd Mudenda, Larysa Nogaieva, Iryna Kryachok, Ganna Usenko, Vladimir Ivanov, Olena Kyselova, Tetiana Perekhrestenko, Ivan Muzhychuk, Alexander Myasnikov, Les Lukavetsky, Andrei Proydakov, Olga Uspenskaya, Elena Borisenkova, Paula Marlton, Tanya Siddiqi, Allison M. Winter, Tamila Lysa, Bulat Akhatovich Bakirov, Tommy Fu, Mingyu Li, Mohammad Ahmad, Zi Chen, Zhiyan Liang, Divya J. Mekala, Olena Karpenko, Iurii Osipov, Asit De, Hengbang Wang, Nashat Gabrail, Vinod Ganju, Tatiana Konstantinova, Olga Samoilova, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2024) 144 (Supplement 1): 4614.
https://doi.org/10.1182/blood-2024-207408
Published: 2024
Journal Articles

First Report on the Effects of Lisaftoclax (APG-2575) in Combination with Novel Therapeutic Regimens in Patients with Relapsed or Refractory Multiple Myeloma (R/R MM) or Immunoglobulin Light-Chain (Amyloid Light-Chain [AL]) Amyloidosis

Sikander Ailawadhi, Asher A. Chanan-Khan, Costas K. Yannakou, Simon Gibbs, Jack Khouri, Zi Chen, Huanshan Guo, Mingyu Li, Mohammad Ahmad, Cunlin Wang, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2023) 142 (Supplement 1): 2016.
https://doi.org/10.1182/blood-2023-188122
Published: 2023
Journal Articles

Alrizomadlin (APG-115) Alone or Combined with Azacitidine (AZA) in Patients (pts) with Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML) or Relapsed or Progressive Higher-Risk Myelodysplastic Syndrome (HR-MDS): Phase 1b Trial Results

Junyuan Qi, Xudong Wei, Qiubai Li, Chukang Chang, Fuling Zhou, Jianying Huang, Yu Zhang, Chongyuan Xu, Xiaowen Tang, Qian Jiang, Junmin Li, Qun Qin, Qun He, Sujun Gao, Liping Liu, Zi Chen, Min Yu, Jing Wang, Lichuang Men, Hengbang Wang, Mohammad Ahmad, Dajun Yang, Yifan Zhai, Jianxiang Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5954.
https://doi.org/10.1182/blood-2023-184959
Published: 2023
Journal Articles

Trial in Progress: Phase 1b/2 Study of Alrizomadlin (APG-115), Alone or Combined with 5-Azacitidine (AZA), in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML), Chronic Myelomonocytic Leukemia (CMML), or Myelodysplastic Syndrome (MDS)

Tapan M. Kadia, Christopher Benton, Harry P. Erba, Mitul Gandhi, Moshe Y. Levy, Mary-Elizabeth M. Percival, Matthew Ulrickson, Habte Yimer, Min Yu, Zi Chen, Jing Wang, Mingyu Li, Mohammad Ahmad, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2022) 140 (Supplement 1): 11659–11660.
https://doi.org/10.1182/blood-2022-162627
Published: 2022
Journal Articles

Lisaftoclax (APG-2575) Safety and Activity As Monotherapy or Combined with Acalabrutinib or Rituximab in Patients (pts) with Treatment-Naïve, Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (R/R CLL/SLL): Initial Data from a Phase 2 Global Study

Matthew S. Davids, Asher Chanan-Khan, Boyd Mudenda, Larysa Nogaieva, Iryna Kriachok, Hanna Usenko, Vladimir Ivanov, Olena Kyselova, Tetiana Perekhrestenko, Ivan Muzhychuk, Alexander Myasnikov, Zvenyslava Maslyak, Andrew Proidakov, Olga Uspenskaya, Elena Borisenkova, Paula Marlton, Tanya Siddiqi, Allison Winter, Tamila Lysa, Bulat Bakirov, Lei Fu, Zi Chen, Min Yu, Mingyu Li, Laura Glass, Mohammad Ahmad, Olena Karpenko, Iurii Osipov, Asit De, Ben Paudyal, Hengbang Wang, Robert Winkler, Nashat Gabrail, Vinod Ganju, Tatiana S. Konstantinova, Olga S. Samoylova, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2022) 140 (Supplement 1): 2326–2328.
https://doi.org/10.1182/blood-2022-160386
Published: 2022
Journal Articles

A Phase 1 Study to Evaluate the Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Lisaftoclax (APG-2575), a Novel BCL-2 Inhibitor (BCL-2i), in Patients (pts) with Certain Relapsed or Refractory (R/R) Hematologic Malignancies (HMs)

Mingyuan Sun, Junyuan Qi, Zi Chen, Hongli Zhang, Yongping Song, Aizong Shen, Huilan Liu, Jianying Huang, Fuling Zhou, Jie Jin, Ming Lu, Mohammad Ahmad, Lichuang Men, Wan Cen, Dajun Yang, Jianxiang Wang, Yifan Zhai
Journal: Blood
Blood (2021) 138 (Supplement 1): 3730.
https://doi.org/10.1182/blood-2021-152235
Published: 2021
Journal Articles

Trial in Progress: Phase 1b Study of Lisaftoclax (APG-2575) As a Single Agent or Combined with Other Therapeutic Agents in Patients with Relapsed and/or Refractory Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (R/R CLL/SLL)

Matthew S. Davids, Tanya Siddiqi, Asher Chanan-Khan, Alan Skarbnik, Allison M. Winter, John M. Pagel, Carrie Smith, Nashat Gabrail, Tetiana Perekhrestenko, Halyna Pylypenko, Olena Kyselova, Olena Karpenko, Tetiana Popovska, Iryna Kriachok, Hanna Usenko, Andrew Proidakov, Vladimir Ivanov, Tamila Lysa, Elena Borisenkova, Bulat Bakirov, Les Lukavetsky, Olga Uspenskaya, Tatiana S. Konstantinova, Olga S. Samoylova, Zi Chen, Bo Huang, Mingyu Li, Mohammad Ahmad, Boyd Mudenda, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2021) 138 (Supplement 1): 1554.
https://doi.org/10.1182/blood-2021-152811
Published: 2021