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Lisaftoclax (APG-2575) Safety and Activity As Monotherapy or Combined with Acalabrutinib or Rituximab in Patients (pts) with Treatment-Naïve, Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (R/R CLL/SLL): Initial Data from a Phase 2 Global Study

Matthew S. Davids, Asher Chanan-Khan, Boyd Mudenda, Larysa Nogaieva, Iryna Kriachok, Hanna Usenko, Vladimir Ivanov, Olena Kyselova, Tetiana Perekhrestenko, Ivan Muzhychuk, Alexander Myasnikov, Zvenyslava Maslyak, Andrew Proidakov, Olga Uspenskaya, Elena Borisenkova, Paula Marlton, Tanya Siddiqi, Allison Winter, Tamila Lysa, Bulat Bakirov, Lei Fu, Zi Chen, Min Yu, Mingyu Li, Laura Glass, Mohammad Ahmad, Olena Karpenko, Iurii Osipov, Asit De, Ben Paudyal, Hengbang Wang, Robert Winkler, Nashat Gabrail, Vinod Ganju, Tatiana S. Konstantinova, Olga S. Samoylova, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2022) 140 (Supplement 1): 2326–2328.
https://doi.org/10.1182/blood-2022-160386
Published: 2022
Journal Articles

Trial in Progress: Phase 1b Study of Lisaftoclax (APG-2575) As a Single Agent or Combined with Other Therapeutic Agents in Patients with Relapsed and/or Refractory Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (R/R CLL/SLL)

Matthew S. Davids, Tanya Siddiqi, Asher Chanan-Khan, Alan Skarbnik, Allison M. Winter, John M. Pagel, Carrie Smith, Nashat Gabrail, Tetiana Perekhrestenko, Halyna Pylypenko, Olena Kyselova, Olena Karpenko, Tetiana Popovska, Iryna Kriachok, Hanna Usenko, Andrew Proidakov, Vladimir Ivanov, Tamila Lysa, Elena Borisenkova, Bulat Bakirov, Les Lukavetsky, Olga Uspenskaya, Tatiana S. Konstantinova, Olga S. Samoylova, Zi Chen, Bo Huang, Mingyu Li, Mohammad Ahmad, Boyd Mudenda, Dajun Yang, Yifan Zhai
Journal: Blood
Blood (2021) 138 (Supplement 1): 1554.
https://doi.org/10.1182/blood-2021-152811
Published: 2021
Journal Articles

Trial in Progress: Phase Ib/II Study of Bcl-2/Bcl-Xl Inhibitor Pelcitoclax (APG-1252) in Patients with Myelofibrosis (MF) That Progressed after Initial Therapy

Naveen Pemmaraju, MD, Boyd Mudenda, MD MSc, MBBChir, Cunlin Wang, MD, Jiao JI, PhD MD, Ming Lu, PhD, Tommy Fu, PhD, Eric Liang, PhD, Sasha McClain, PharmD, Piyush Sheladia, MS, Srdan Verstovsek, MD PhD, Dajun Yang, MD PhD, Yifan Zhai, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-137260
Published: 2020