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Journal Articles

Improved Outcomes for Pediatric B-ALL but Inferior Survival for T-ALL Using the Same Treatment Protocol: Results of Consecutive Malaysia-Singapore 2003 and 2010 Childhood ALL Trials

Shawn H.R. Lee, Bernice Oh, Prasad Iyer, Yiong Huat Chan, Kean Hui Chiew, Shirley Kow Yin Kham, Michaela Su-Fern Seng, Joyce CM Lam, Lee Lee Chan, Thuan Chong Quah, Hai Peng Lin, Ah Moy Tan, Hany Ariffin, Allen Eng Juh Yeoh

Blood (2024) 144 (Supplement 1): 4192.

https://doi.org/10.1182/blood-2024-193344

Published: 2024

Journal Articles

Haploidentical Hematopoietic Cell Transplantation of Ex Vivo Tcrαβ-Depleted Grafts with CD45RA-Depleted Memory T Cell Add-Back Reduces Chronic Graft-Versus-Host Disease and Results in Favourable Gvhd-Relapse Free Survival: 5-Year Follow-up of 107 Patients Treated in a Multicenter Study in Singapore

Blood (2022) 140 (Supplement 1): 4707–4708.

https://doi.org/10.1182/blood-2022-168995

Published: 2022

Journal Articles

HLA-Haploidentical Hematopoietic Cell Transplantation of Ex Vivo Tcrαβ-Depleted Grafts with CD45RA-Depleted Memory T Cell Add-Back in Adults and Children with Hematological Malignancies: 4-Year Follow-up of Multicenter Study in Singapore

Ian Q Wu, Yeh Ching Linn, Yang Liang Boo, Rajat Bhattacharyya, Zi Yi Lim, Michelle Poon, Michaela Su-Fern Seng, Poh Lin Tan, Colin Phipps, Balamurugan Vellayappan, Ah Moy Tan, Lip Kun Tan, Yvonne Su Ming Loh, Teck Guan Soh, Gina Gan, Yin Jie Koh, Wing H. Leung, Liang Piu Koh

Blood (2021) 138 (Supplement 1): 555.

https://doi.org/10.1182/blood-2021-152372

Published: 2021

Journal Articles

The Impact of Genetic Ancestry on the Biology and Prognosis of Childhood Acute Lymphoblastic Leukemia

Blood (2021) 138 (Supplement 1): 3476.

https://doi.org/10.1182/blood-2021-145655

Published: 2021

Journal Articles

HLA-Haploidentical Hematopoietic Cell Transplantation after TCR-Αβ and CD45RA+ Depletion Following Reduced Intensity Conditioning in Adults and Children with Hematological Malignancies: Three-Year Follow-up of Multicenter Study in Singapore

Yang Liang Boo, MD, Yeh Ching Linn, MBBS, MRCP, Rajat Bhattacharyya, Michelle Li Mei Poon, MBBS, MRCP, Zi Yi Lim, MB ChB, Michaela Su-Fern Seng, MBBS, Poh Lin Tan, MBBS, Colin Phipps Diong, MB BCh BAO, Balamurugan Vellayappan, MBBS, Ah Moy Tan, MD, Lip Kun Tan, MBBS, FRCP, FRCPath, Yvonne Su Ming Loh, MBBS, Teck Guan Soh, Gina Gan, Yin Jie Koh, Wing Hang Leung, MBBS, Liang Piu Koh, MBBS, MRCP

Blood (2020) 136 (Supplement 1): 8–9.

https://doi.org/10.1182/blood-2020-138638

Published: 2020

Journal Articles

Successful Toxicity Reduction in Ma-Spore ALL 2010 in Standard/Intermediate Risk Childhood ALL: Replacing Cytarabine/Doxorubicin with More Vincristine and L-Asparaginase during Consolidation and Delayed Intensification

Bernice Oh, MBBS, MRCP, Shawn Lee, MD, Zelia Seeto, Germaine Liew, Bsc, Edwynn Chiew, MBBS, Zhi Wei Chen, Bsc, Yiong Huak Chan, PhD, Jing Jia Eng, Bsc, Koon Mian Foo, Bsc, Ching Mei Joyce Lam, MD, Ah Moy Tan, MD, Allen Eng Juh Yeoh, MD

Blood (2019) 134 (Supplement_1): 1307.

https://doi.org/10.1182/blood-2019-122098

Published: 2019

Journal Articles

HLA-Haploidentical Hematopoietic Cell Transplantation after TCR-Αβ and CD45RA+ Depletion Following Reduced Intensity Conditioning in Adults and Children with Hematological Malignancies- Two-Year Follow-up of Multicenter Study in Singapore

Li Mei Poon, MBBS, MRCP, FRCPath, Yeh Ching Linn, MBBS, MRCP, Poh Lin Tan, Ziyi LIM, Balamurugan Vellayappan, Rajat Bhattacharyya, Ah Moy Tan, MD, Lip Kun Tan, MBBS, FRCP, FRCPath, Teck Guan Soh, Colin Phipps Diong, Wing H. Leung, MD PhD, Liang Piu Koh, MBBS, MRCP

Blood (2019) 134 (Supplement_1): 2039.

https://doi.org/10.1182/blood-2019-128014

Published: 2019

Journal Articles

RNA Sequencing in Childhood B-Lymphoblastic Leukemia Improves Molecular and Risk Assignment

Allen Eng Juh Yeoh, MD, Zhenhua Li, PhD, Shawn Lee, MD, Winnie Hui Ni Chin, Nan Jiang, PhD, Yi Lu, PhD, Shirley Kow Yin Kham, BSc, Ah Moy Tan, MD, Hai_peng Lin, Thuan Chong Quah, Hany Ariffin, Jun J. Yang, PhD

Blood (2019) 134 (Supplement_1): 651.

https://doi.org/10.1182/blood-2019-131653

Published: 2019

Journal Articles

RNA-Seq Can Help Identify IGH Disease Clones for MRD Monitoring in Childhood B-Lymphoblastic Leukemia

Zhenhua Li, PhD, Nan Jiang, PhD, Evelyn Huizi Lim, Winnie Hui Ni Chin, Shirley Kow Yin Kham, BSc, Wentao Yang, Thuan Chong Quah, Hai_peng Lin, Ah Moy Tan, MD, Hany Ariffin, Jun J. Yang, PhD, Allen Eng Juh Yeoh, MD

Blood (2019) 134 (Supplement_1): 1471.

https://doi.org/10.1182/blood-2019-131548

Published: 2019

Journal Articles

HLA-Haploidentical Hematopoietic Cell Transplantation after TCR-Alpha Beta and CD45RA+ Depletion Following Reduced Intensity Conditioning in Adults and Children with Hematological Malignancies

Liang Piu Koh, MBBS, MRCP, Wing H. Leung, MD PhD, Michelle Poon, Lip Kun Tan, Poh Lin Tan, Balamurugan Vellayappan, Rajat Bhattacharyya, Ah Moy Tan, MD, Teck Guan Soh, Yeh Ching Linn, MBBS, MRCP

Blood (2018) 132 (Supplement 1): 2093.

https://doi.org/10.1182/blood-2018-99-116296

Published: 2018

Journal Articles

Intensifying Treatment in Childhood B-Lymphoblastic Leukemia with IKZF1 Deletions Negates Its Adverse Outcome: Results of Ma-Spore ALL 2003 and 2010 Studies

Yi Lu, PhD, Winnie Hui Ni Chin, Evelyn Huizi Lim, Shirley Kow Yin Kham, BSc, Ah Moy Tan, MD, Hany Ariffin, MD PhD, Allen Eng Juh Yeoh, MD

Blood (2017) 130 (Supplement 1): 478.

https://doi.org/10.1182/blood.V130.Suppl_1.478.478

Published: 2017

Journal Articles

Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations

Blood (2017) 129 (24): 3264–3268.

https://doi.org/10.1182/blood-2017-03-771162

Published: 2017

Includes: Supplemental data

Journal Articles

Effective Response Metric (ERM-D8) Using Time-Series Gene Expression Profiling at Diagnosis and Day 8 of Remission-Induction Therapy Is a Novel Early Prognostic Marker to Predict Relapse in Childhood Acute Lymphoblastic Leukemia (ALL) — a Malaysia-Singapore ALL Study

Allen Eng Juh Yeoh, MD, Zhenhua Li, PhD, Difeng Dong, PhD, Yi Lu, PhD, Jan Trka, MD, PhD, Prof., Shirley Kow Yin Kham, B.Sc., Ah Moy Tan, MD, Hany Ariffin, MD, Limsoon Wong, PhD

Blood (2014) 124 (21): 2393.

https://doi.org/10.1182/blood.V124.21.2393.2393

Published: 2014

Journal Articles

Genomic Profiling of Pharmacogenetic Variants Establishes a SNP-Based Predictor for Poor Outcome in Asian Children with Acute Lymphoblastic Leukemia (ALL): A Report from Malaysia-Singapore ALL Study Group

Yi Lu, PhD, Marc Hai Liang Wong, M.B.,B.S., Zhenhua Li, PhD, Shirley Kow Yin Kham, B.Sc., Ah Moy Tan, MD, Hany Ariffin, MD, Allen Eng Juh Yeoh, MD

Blood (2014) 124 (21): 1069.

https://doi.org/10.1182/blood.V124.21.1069.1069

Published: 2014

Journal Articles

Host Pharmacogenetic Factors Significantly Contribute to Refinement of Prognosis in Children with Acute Lymphoblastic Leukemia (ALL): Result From the Malaysia-Singapore (Ma-Spore) ALL 2003 Study

Yi Lu, Ph.D., Shirley Kow Yin Kham, B.Sc., Arrifin Hany, M.D., Ah Moy Tan, M.D., Thuan Chong Quah, M.D., Allen Eng Juh Yeoh, M.D.

Blood (2011) 118 (21): 567.

https://doi.org/10.1182/blood.V118.21.567.567

Published: 2011

Journal Articles

Integrated Molecular and Pharmacogenetic Profiles in Prediction of Early Response to Therapy in Children with Acute Lymphoblastic Leukemia (ALL): A Report From Malaysia-Singapore ALL Study Group.

Yi Lu, Ph.D., Shirley Kow Yin Kham, B.Sc., Hany Ariffin, M.D., Ah Moy Tan, M.D., Hai Peng Lin, M.D., Thuan Chong Quah, M.D., Allen Eng Juh Yeoh, M.D.

Blood (2009) 114 (22): 2624.

https://doi.org/10.1182/blood.V114.22.2624.2624

Published: 2009

Journal Articles

Analysis of 120 Pediatric Patients with Non-Malignant Disorders Transplanted Using Unrelated Plasma Depleted Cord Blood and the Role of Post-Thaw Wash

Joseph Rosenthal, MD, MS, Tang-Her Jaing, MD, Lee Lee Chan, MD, Gretchen Eames, MD, Michael L. Graham, MD, Ah Moy Tan, MD, Hai Peng Lin, MD, Auayporn P. Nademanee, MD, Chatchada Karanes, MD, Brian Wang, MS, Tina Wu, Tiffany Chow, Patrick Tan, MD, David Gjertson, PhD, Lawrence Petz, MD, Stephen J. Forman, MD, Robert Chow, MD

Blood (2008) 112 (11): 4406.

https://doi.org/10.1182/blood.V112.11.4406.4406

Published: 2008

Journal Articles

Single IGH/TCR MRD Marker Is More Informative and Cost-Effective in Risk-Stratified Therapy for Childhood ALL: Prospective Treatment Trial Results from the Malaysia-Singapore (Ma-Spore) ALL 2003 Study

Allen Eng Juh Yeoh, MD, Hany Ariffin, MD, Ah Moy Tan, MD, Thi Thu Ha Truong, BSc, Hai Peng Lin, MD, Yiong Huak Chan, PhD, Shirley Kow Yin Kham, BSc, Thuan Chong Quah, MD

Blood (2008) 112 (11): 2551.

https://doi.org/10.1182/blood.V112.11.2551.2551

Published: 2008

Journal Articles

Unrelated Cord Blood Transplants in Children/Adolescents in Multi-Racial Singapore.

Poh-Lin Tan, MD, Ah-Moy Tan, MD, Mei-Yoke Chan, MD, Mariflor Villegas, MD, Allen Yeoh, MD, Thuan-Chong Quah, MD

Blood (2007) 110 (11): 5089.

https://doi.org/10.1182/blood.V110.11.5089.5089

Published: 2007

Journal Articles

Post-That Washing Prior to Transplantation of Umbilical Cord Blood (UCB) That Were Depleted of Plasma but Not of Red Blood Cells.

Robert Chow, MD, Patrick Tan, M.D., Tang-Her Jaing, M.D., Joseph Rosenthal, M.D., Auayporn Nademanee, M.D., Chatchada Karanes, M.D., Michael Graham, M.D., Gretchen Eames, M.D., Lee Lee Chan, M.D., Brian Wang, M.S., Tiffany Chow, Tina Wu, Ah Moy Tan, M.D., Poh-Lin Tan, M.D., Hai-Peng Lin, M.D., David Gjertson, PhD, Lawrence Petz, M.D.

Blood (2006) 108 (11): 5229.

https://doi.org/10.1182/blood.V108.11.5229.5229

Published: 2006

NARROW

Improved Outcomes for Pediatric B-ALL but Inferior Survival for T-ALL Using the Same Treatment Protocol: Results of Consecutive Malaysia-Singapore 2003 and 2010 Childhood ALL Trials

HLA-Haploidentical Hematopoietic Cell Transplantation of Ex Vivo Tcrαβ-Depleted Grafts with CD45RA-Depleted Memory T Cell Add-Back in Adults and Children with Hematological Malignancies: 4-Year Follow-up of Multicenter Study in Singapore

The Impact of Genetic Ancestry on the Biology and Prognosis of Childhood Acute Lymphoblastic Leukemia

HLA-Haploidentical Hematopoietic Cell Transplantation after TCR-Αβ and CD45RA+ Depletion Following Reduced Intensity Conditioning in Adults and Children with Hematological Malignancies: Three-Year Follow-up of Multicenter Study in Singapore

Successful Toxicity Reduction in Ma-Spore ALL 2010 in Standard/Intermediate Risk Childhood ALL: Replacing Cytarabine/Doxorubicin with More Vincristine and L-Asparaginase during Consolidation and Delayed Intensification

HLA-Haploidentical Hematopoietic Cell Transplantation after TCR-Αβ and CD45RA+ Depletion Following Reduced Intensity Conditioning in Adults and Children with Hematological Malignancies- Two-Year Follow-up of Multicenter Study in Singapore

RNA Sequencing in Childhood B-Lymphoblastic Leukemia Improves Molecular and Risk Assignment

RNA-Seq Can Help Identify IGH Disease Clones for MRD Monitoring in Childhood B-Lymphoblastic Leukemia

HLA-Haploidentical Hematopoietic Cell Transplantation after TCR-Alpha Beta and CD45RA+ Depletion Following Reduced Intensity Conditioning in Adults and Children with Hematological Malignancies

Intensifying Treatment in Childhood B-Lymphoblastic Leukemia with IKZF1 Deletions Negates Its Adverse Outcome: Results of Ma-Spore ALL 2003 and 2010 Studies

Whole-genome noncoding sequence analysis in T-cell acute lymphoblastic leukemia identifies oncogene enhancer mutations

Effective Response Metric (ERM-D8) Using Time-Series Gene Expression Profiling at Diagnosis and Day 8 of Remission-Induction Therapy Is a Novel Early Prognostic Marker to Predict Relapse in Childhood Acute Lymphoblastic Leukemia (ALL) — a Malaysia-Singapore ALL Study

Genomic Profiling of Pharmacogenetic Variants Establishes a SNP-Based Predictor for Poor Outcome in Asian Children with Acute Lymphoblastic Leukemia (ALL): A Report from Malaysia-Singapore ALL Study Group

Host Pharmacogenetic Factors Significantly Contribute to Refinement of Prognosis in Children with Acute Lymphoblastic Leukemia (ALL): Result From the Malaysia-Singapore (Ma-Spore) ALL 2003 Study

Integrated Molecular and Pharmacogenetic Profiles in Prediction of Early Response to Therapy in Children with Acute Lymphoblastic Leukemia (ALL): A Report From Malaysia-Singapore ALL Study Group.

Analysis of 120 Pediatric Patients with Non-Malignant Disorders Transplanted Using Unrelated Plasma Depleted Cord Blood and the Role of Post-Thaw Wash

Single IGH/TCR MRD Marker Is More Informative and Cost-Effective in Risk-Stratified Therapy for Childhood ALL: Prospective Treatment Trial Results from the Malaysia-Singapore (Ma-Spore) ALL 2003 Study

Unrelated Cord Blood Transplants in Children/Adolescents in Multi-Racial Singapore.

Post-That Washing Prior to Transplantation of Umbilical Cord Blood (UCB) That Were Depleted of Plasma but Not of Red Blood Cells.

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American Society of Hematology

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