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Cicera Lazzarotto
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Journal Articles

Increased Potency and Uniformity of Fetal Hemoglobin Induction from Base Editing Compared to Cas9 Nuclease

Thiyagaraj Mayuranathan, Gregory A. Newby, Ruopeng Feng, Yu Yao, Kalin Mayberry, Guolian Kang, Cicera Lazzarotto, Yichao Li, Rachel Levine, Erin Dempsey, Shaina N. Porter, Phillip A Doerfler, Jingjing Zhang, Yoonjeong Jang, Senthil Bhoopalan, Nikitha Nimmagadda, Akshay Sharma, John Tisdale, Shondra Miller, Yong Cheng, Shengdar Tsai, Mitchell J. Weiss, David R. Liu, Jonathan S Yen
Journal: Blood
Blood (2022) 140 (Supplement 1): 7784–7785.
https://doi.org/10.1182/blood-2022-162639
Published: 2022
Journal Articles

Highly Efficient & Specific Repair of MAGT1 Mutation in Xmen Patient T Cells and Hematopoietic Stem Cells

Vera Bzhilyanskaya, Julie Brault, Siyuan Liu, Andres F. Zea Vera, Nikita Kozhushko, Amanda Lawson, Uimook Choi, Aaron B. Clark, Ronald J. Meis, Michelle Ma, Cicera Lazzarotto, Shengdar Tsai, Xiaolin Wu, Gary A. Dahl, Jenna Bergerson, Alexandra F. Freeman, Benjamin Kleinstiver, Harry L Malech, Suk See De Ravin
Journal: Blood
Blood (2022) 140 (Supplement 1): 7766–7767.
https://doi.org/10.1182/blood-2022-170252
Published: 2022
Journal Articles

CRISPR-Cas9 Genome Editing of γ-Globin Promoters in Human Hematopoietic Stem Cells to Induce Erythrocyte Fetal Hemoglobin for Treatment of β-Hemoglobinopathies

Jean-Yves Metais, PhD, Phillip A Doerfler, PhD, Thiyagaraj Mayuranathan, Daniel E. Bauer, MD PhD, Stephanie Fowler, Matthew Hsieh, MD, Varun Katta, Sagar Keriwala, Cicera Lazzarotto, Kevin Luk, Michael Neel, Scott Perry, Shaina Porter, Byoung Y. Ryu, PhD, Akshay Sharma, MBBS, Devlin Shea, Samuel Peters, John F. Tisdale, MD, Scot A. Wolfe, PhD, Kaitly Jensen Woodard, BS, Naoya Uchida, MD, Yuxuan Wu, PhD, Yu Yao, MD, Jing Zeng, MD, Shondra M. Pruett-Miller, PhD, Shengdar Q. Tsai, PhD, Mitchell J. Weiss, MD, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2066.
https://doi.org/10.1182/blood-2019-131318
Published: 2019