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Allen Krouse
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Journal Articles

CD117 Antibody-Drug Conjugate Conditioning Allows Efficient Engraftment of Gene-Modified CD34+ Cells with Fertility Preservation in a Rhesus Gene Therapy Model

Naoya Uchida, Selami Demirci, Anh Le, Rebecca Chu, Xiong Liu, Ling Su, Xiaolin Wu, Allen Krouse, N Seth Linde, Aylin Bonifacino, So Gun Hong, Cynthia E. Dunbar, Leanne Lanieri, Anjali Bhat, Rahul Palchaudhuri, Bindu Bennet, Megan D. Hoban, Kirk Bertelsen, Lisa Olson, Robert Donahue, John F. Tisdale
Journal: Blood
Blood (2023) 142 (Supplement 1): 486.
https://doi.org/10.1182/blood-2023-177815
Published: 2023
Journal Articles

Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation Model

Naoya Uchida, MD, Linhong Li, PhD, Tina Nassehi, Morgan Yapundich, Jackson Gamer, Claire Drysdale, Juan J. Haro-Mora, PhD, Selami Demirci, PhD, Aylin Bonifacino, MS, Allen Krouse, Nathaniel S. Linde, Cornell Allen, MS, Suk See De Ravin, MD, PhD, Robert E. Donahue, VMD, Harry L. Malech, MD, Madhusudan Peshwa, PhD, John F. Tisdale, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 609.
https://doi.org/10.1182/blood-2019-122727
Published: 2019
Journal Articles

A Single Dose of CD117 Antibody Drug Conjugate Enables Autologous Gene-Modified Hematopoietic Stem Cell Transplant (Gene Therapy) in Nonhuman Primates

John F. Tisdale, MD, Robert E. Donahue, VMD, Naoya Uchida, MD, Bradley R Pearse, PhD, Sean M McDonough, MS, Jennifer L Proctor, BS, Allen Krouse, Nathaniel S. Linde, Aylin C. Bonifacino, Rajiv Panwar, PhD, Ganapathy N. Sarma, PhD, Lena Kien, BS, Kellie Latimer, Junia Dushime, BS, Sharon L. Hyzy, MS, Melissa L. Brooks, BS, Rahul Palchaudhuri, PhD, Qing Li, PhD, Pranoti Sawant, MS, Charlotte F McDonagh, PhD, Anthony E. Boitano, PhD, Michael P. Cooke, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 610.
https://doi.org/10.1182/blood-2019-125968
Published: 2019
Journal Articles

Truncated Erythropoietin Receptors Confer an In Vivo Selective Advantage in Gene-Modified Erythroid Cells Expressing Fetal Hemoglobin Due to BCL11A Interference

Naoya Uchida, MD, Claire Drysdale, Morgan Yapundich, Jackson Gamer, Tina Nassehi, Matthew Wielgosz, Francesca Ferrara, PhD, Juan J. Haro-Mora, PhD, Selami Demirci, PhD, Aylin Bonifacino, MS, Allen Krouse, Nathaniel S. Linde, Robert E. Donahue, VMD, Byoung Y. Ryu, PhD, John F. Tisdale, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2063.
https://doi.org/10.1182/blood-2019-122770
Published: 2019
Journal Articles

Intrabone Delivery of CD34+ Cells Using an Optimized Delivery System Does Not Enhance Engraftment in a Rhesus Macaque Model of Hematopoietic Stem Cell Transplantation

Kate Stringaris, MD PhD, Robert F Hoyt, Jan Davidson, Jeremy Pantin, MBBS, John F. Tisdale, MD, Naoya Uchida, MD, Lydia Raines, Robert Reger, MS, Noriko Sato, Cynthia E. Dunbar, MD, Tim Hunt, Randy Clevenger, Allen Krouse, Mark Metzger, Aylin Bonifacino, MS, Theresa Engels, Sandra Price, Peter Choyke, MD, Robert E. Donahue, VMD, Richard W. Childs, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5677.
https://doi.org/10.1182/blood-2018-99-114730
Published: 2018
Journal Articles

The impact of aging on primate hematopoiesis as interrogated by clonal tracking

Kyung-Rok Yu, Diego A. Espinoza, Chuanfeng Wu, Lauren Truitt, Tae-Hoon Shin, Shirley Chen, Xing Fan, Idalia M. Yabe, Sandhya Panch, So Gun Hong, Samson Koelle, Rong Lu, Aylin Bonifacino, Allen Krouse, Mark Metzger, Robert E. Donahue, Cynthia E. Dunbar
Journal: Blood
Blood (2018) 131 (11): 1195–1205.
https://doi.org/10.1182/blood-2017-08-802033
Published: 2018
Includes: Supplemental data
Journal Articles

Aberrant Clonal Hematopoiesis of the Erythroid and Myeloid Lineages in a Lentivirally Barcoded Rhesus Macaque

Diego A Espinoza, BA, Chuanfeng Wu, MD, Xing Fan, MD, Di Yang, MD, Idalia Montano Yabe, MS, Selami Demirci, PhD, So Gun Hong, PhD, Aylin Bonifacino, MS, Allen Krouse, Mark Metzger, Rong Lu, PhD, Katherine R Calvo, MD PhD, John F Tisdale, MD, Xiaolin Wu, PhD, Suk See De Ravin, MD PhD, Harry L Malech, MD, Robert E Donahue, VMD, Cynthia E Dunbar, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 606.
https://doi.org/10.1182/blood.V130.Suppl_1.606.606
Published: 2017
Journal Articles

AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates

André Larochelle, Allen Krouse, Mark Metzger, Donald Orlic, Robert E. Donahue, Simon Fricker, Gary Bridger, Cynthia E. Dunbar, Peiman Hematti
Journal: Blood
Blood (2006) 107 (9): 3772–3778.
https://doi.org/10.1182/blood-2005-09-3592
Published: 2006
Journal Articles

Mobilization as a Preparative Regimen for Hematopoietic Stem Cell (HSC) Transplantation in Rhesus Macaques.

Andre Larochelle, MD, PhD, Cynthia L. Perez, MSc, Allen Krouse, Mark Metzger, Simon Fricker, PhD, Gary Bridger, PhD, Donald Orlic, MD, Robert E. Donahue, DVM, Janis L. Abkowitz, MD, Cynthia E. Dunbar, MD
Journal: Blood
Blood (2005) 106 (11): 1709.
https://doi.org/10.1182/blood.V106.11.1709.1709
Published: 2005
Journal Articles

AMD3100-Mobilized CD34+ Cells Are Phenotypically Different and Better Targets for Retroviral Transduction Than G-CSF-Mobilized CD34+ Cells in Rhesus Macaques.

Andre Larochelle, MD PhD, Allen Krouse, Donald Orlic, MD, Robert E. Donahue, DVM, Cynthia E. Dunbar, MD, Peiman Hematti, MD
Journal: Blood
Blood (2004) 104 (11): 2686.
https://doi.org/10.1182/blood.V104.11.2686.2686
Published: 2004
Journal Articles

In Vitro Culture during Retroviral Transduction Improves Thymic Repopulation and Output after TBI and Autologous PBPC Transplantation in Rhesus Macaques.

Ruth Seggewiss, MD, Karin Lore, PhD, Javier F. Guenaga, Stefania Pittaluga, MD PhD, Mark E. Metzger, Allen Krouse, Robert E. Donahue, VMD, David Ambrozak, Daniel C. Douek, MD PhD, Cynthia E. Dunbar, MD
Journal: Blood
Blood (2004) 104 (11): 1196.
https://doi.org/10.1182/blood.V104.11.1196.1196
Published: 2004
Journal Articles

Cloning and Functional Analysis of the Rhesus Macaque ABCG2 Gene: Forced Expression Confers an SP Phenotype among Hematopoietic Stem Cell Progeny in Vivo.

Takahiro Ueda, M.D., Sebastian Brenner, M.D., Harry Malech, M.D., Saskia Langemeijer, Martha Kirby, Oswald Phang, Allen Krouse, Robert E. Donahue, D.V.M., Elizabeth M. Kang, M.D., John F. Tisdale, M.D.
Journal: Blood
Blood (2004) 104 (11): 3219.
https://doi.org/10.1182/blood.V104.11.3219.3219
Published: 2004
Journal Articles

The impact of low-dose busulfan on clonal dynamics in nonhuman primates

Ken Kuramoto, Dean Follman, Peiman Hematti, Stephanie Sellers, Mikko O. Laukkanen, Ruth Seggewiss, Mark E. Metzger, Allen Krouse, Robert E. Donahue, Christof von Kalle, Cynthia E. Dunbar
Journal: Blood
Blood (2004) 104 (5): 1273–1280.
https://doi.org/10.1182/blood-2003-08-2935
Published: 2004
Journal Articles

Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus–based lentiviral vector system

Hideki Hanawa, Peiman Hematti, Keyvan Keyvanfar, Mark E. Metzger, Allen Krouse, Robert E. Donahue, Steve Kepes, John Gray, Cynthia E. Dunbar, Derek A. Persons, Arthur W. Nienhuis
Journal: Blood
Blood (2004) 103 (11): 4062–4069.
https://doi.org/10.1182/blood-2004-01-0045
Published: 2004