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Journal Articles

Significant mobilization of both conventional and regulatory T cells with AMD3100

Leslie S. Kean, Sharon Sen, Olusegun Onabajo, Karnail Singh, Jennifer Robertson, Linda Stempora, Aylin C. Bonifacino, Mark E. Metzger, Daniel E. L. Promislow, Joseph J. Mattapallil, Robert E. Donahue

Blood (2011) 118 (25): 6580–6590.

https://doi.org/10.1182/blood-2011-06-359331

Published: 2011

Includes: Supplemental data

Journal Articles

Evidence for Quantitative and Functional Immune Deviation in Pediatric Patients with Sickle Cell Disease

Leslie Kean, MD, PHD, Sharon Sen, Martha Ann Felder, CRA, VIN Tangpricha, MD, PHD, Olufolake Adisa, MD, Angelica JAMES-Herry, MD, Iris Buchanan, MD, MSC, Thomas Ziegler, Jessica Alvarez, RD, PhD, Jonathan Beus, Diana Worthington-White, RN, CRA, Jennifer Robertson, PhD, Jackie George, BS, Joshua Cetron, Solomon Fiifi Ofori-Acquah, PhD, Ifeyinwa Osunkwo, MD, MPH

Blood (2011) 118 (21): 1054.

https://doi.org/10.1182/blood.V118.21.1054.1054

Published: 2011

Journal Articles

CD28-Directed T Cell Costimulation Blockade with Abatacept to Prevent GvHD During High-Risk Unrelated HSCT: A First-in-Disease Feasibility Trial,

Leslie S. Kean, MD, PhD, Amelia Langston, MD, Muna Qayad, MD, H. Jean Khoury, MD, FACP, Divya Tiwari, MD, Cynthia Couture, Heather Renfroe, Sharon Sen, Jennifer Robertson, PhD, Edmund K Waller, MD PhD, John T. Horan

Blood (2011) 118 (21): 4078.

https://doi.org/10.1182/blood.V118.21.4078.4078

Published: 2011

Journal Articles

GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28 − CD8 + T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression

Blood (2010) 116 (24): 5403–5418.

https://doi.org/10.1182/blood-2010-06-289272

Published: 2010

Includes: Supplemental data

Journal Articles

Sirolimus and GvHD Control: the Rhesus Macaque GvHD Model Reveals That Sirolimus Preferentially Inhibits T Cell Proliferation While Permitting Breakthrough T cell Activation After MHC-Mismatched Hematopoietic Stem Cell Transplantation

Karnail Singh, Swetha Srinivasan, Angela Panoskaltsis-Mortari, PhD, Sharon Sen, Kelly Hamby, Taylor Deane, Linda Stempora, Frank Leopardi, John Shires, Jonathan Beus, Benjamin Byrd, Bruce R. Blazar, MD, Leslie Kean, MD, PhD

Blood (2010) 116 (21): 2549.

https://doi.org/10.1182/blood.V116.21.2549.2549

Published: 2010

Journal Articles

GvHD After Haploidentical Transplant: A Novel, MHC-Defined Rhesus Macaque Model Identifies CD28-Negative CD8+ T Cells as a Reservoir of Breakthrough T Cell Proliferation During Costimulation Blockade and Sirolimus-Based Immunosuppression

Swetha Srinivasan, Weston P. Miller IV, MD, Angela Panoskalltsis-Mortari, Sharon Sen, Kelly Hamby, Taylor Deane, Linda Stempora, Karnail Singh, Jonathan Beus, Bruce R. Blazar, MD, Leslie Kean, MD, PhD

Blood (2010) 116 (21): 2550.

https://doi.org/10.1182/blood.V116.21.2550.2550

Published: 2010

Journal Articles

Probing the Impact of AMD3100/GCSF Mobilization on the Peripheral Blood T Cell Content Using a Rhesus Macaque Model: Increased Proportions of FoxP3+/CD4+ T Cells Occur After Mobilization and Leukapheresis

Leslie Kean, MD, PhD, Sharon Sen, Mark E Metzger, Aylin Bonifacino, Karnail Singh, Robert E Donahue, VMD

Blood (2010) 116 (21): 350.

https://doi.org/10.1182/blood.V116.21.350.350

Published: 2010

NARROW

Significant mobilization of both conventional and regulatory T cells with AMD3100

Evidence for Quantitative and Functional Immune Deviation in Pediatric Patients with Sickle Cell Disease

CD28-Directed T Cell Costimulation Blockade with Abatacept to Prevent GvHD During High-Risk Unrelated HSCT: A First-in-Disease Feasibility Trial,

GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28 − CD8 + T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression

Sirolimus and GvHD Control: the Rhesus Macaque GvHD Model Reveals That Sirolimus Preferentially Inhibits T Cell Proliferation While Permitting Breakthrough T cell Activation After MHC-Mismatched Hematopoietic Stem Cell Transplantation

GvHD After Haploidentical Transplant: A Novel, MHC-Defined Rhesus Macaque Model Identifies CD28-Negative CD8+ T Cells as a Reservoir of Breakthrough T Cell Proliferation During Costimulation Blockade and Sirolimus-Based Immunosuppression

Probing the Impact of AMD3100/GCSF Mobilization on the Peripheral Blood T Cell Content Using a Rhesus Macaque Model: Increased Proportions of FoxP3+/CD4+ T Cells Occur After Mobilization and Leukapheresis

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ASH Publications

American Society of Hematology

Significant mobilization of both conventional and regulatory T cells with AMD3100

Evidence for Quantitative and Functional Immune Deviation in Pediatric Patients with Sickle Cell Disease

CD28-Directed T Cell Costimulation Blockade with Abatacept to Prevent GvHD During High-Risk Unrelated HSCT: A First-in-Disease Feasibility Trial,

GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28 − CD8 + T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression

Sirolimus and GvHD Control: the Rhesus Macaque GvHD Model Reveals That Sirolimus Preferentially Inhibits T Cell Proliferation While Permitting Breakthrough T cell Activation After MHC-Mismatched Hematopoietic Stem Cell Transplantation

GvHD After Haploidentical Transplant: A Novel, MHC-Defined Rhesus Macaque Model Identifies CD28-Negative CD8+ T Cells as a Reservoir of Breakthrough T Cell Proliferation During Costimulation Blockade and Sirolimus-Based Immunosuppression

Probing the Impact of AMD3100/GCSF Mobilization on the Peripheral Blood T Cell Content Using a Rhesus Macaque Model: Increased Proportions of FoxP3+/CD4+ T Cells Occur After Mobilization and Leukapheresis

Email alerts

ASH Publications

American Society of Hematology

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