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Journal Articles

Neutrophil Elastase Catalytic Activity Regulates Granulopoiesis

Sudeshna Seal, Michelle Krutein, Donovan Anderson, Marshall Horwitz

Blood (2023) 142 (Supplement 1): 1168.

https://doi.org/10.1182/blood-2023-180280

Published: 2023

Journal Articles

Interplay between Inflammatory Microenvironment and RUNX1-Mediated Transcriptomic Changes Drives Defective Hematopoiesis in Familial Platelet Disorder

Blood (2023) 142 (Supplement 1): 945.

https://doi.org/10.1182/blood-2023-187750

Published: 2023

Journal Articles

Conditional Expression of Mutant ELANE Produces Unfolded Protein Response but Fails to Promote Cell Death or Differentiation Block: What Is the Mechanism for Severe Congenital Neutropenia?

Hrishikesh M Mehta, PhD, Arighno Das, BA, Ralph Kamel, MD, Marshall Horwitz, MD PhD, Seth Corey, MD MPH

Blood (2016) 128 (22): 3899.

https://doi.org/10.1182/blood.V128.22.3899.3899

Published: 2016

Journal Articles

Insights from Familial Leukemia and Myelodysplastic Syndromes

Marshall Horwitz, MD, PhD

Blood (2013) 122 (21): SCI-6.

https://doi.org/10.1182/blood.V122.21.SCI-6.SCI-6

Published: 2013

Journal Articles

Targeted correction Of RUNX1 Mutation In The FPD Patient-Specific Induced Pluripotent Stem Cells Restores Megakaryocytic Differentiation

Erika Mijin Kwon, PhD, Jon P Connelly, PhD, Yongxing Gao, BS, Marshall Horwitz, MD, PhD, Linzhao Cheng, PhD, Pu Paul Liu, MD, PhD

Blood (2013) 122 (21): 738.

https://doi.org/10.1182/blood.V122.21.738.738

Published: 2013

Journal Articles

Neutrophil elastase unleashed

Marshall Horwitz

Blood (2005) 105 (9): 3392–3393.

https://doi.org/10.1182/blood-2005-02-0637

Published: 2005

Journal Articles

G-CSF receptor mutations mix it up

Marshall Horwitz

Blood (2005) 105 (2): 440.

https://doi.org/10.1182/blood-2004-10-3902

Published: 2005

Journal Articles

Acquired Mutation and Reversion of the Neutrophil Elastase Gene, ELA2 , in Kostmann Syndrome and Cyclic Neutropenia Suggest that Some Mutations Cause Neutropenia while Others Paradoxically Suppress It.

Kathleen F. Benson, PhD, Kayleen Williams, BS, Joanna Luty, MD, Valeh Hadavi, MS, Roxana Kariminejad, MS, Mohammad H. Kariminejad, MD, PhD, Marshall Horwitz, MD, PhD

Blood (2004) 104 (11): 781.

https://doi.org/10.1182/blood.V104.11.781.781

Published: 2004

Journal Articles

Low levels of serum elastase are not associated with mutations in ELA-2 elastase encoding gene in chronic idiopathic neutropenia

Helen A. Papadaki, Marshall Horwitz, Stavroula A. Coulocheri, Richard A. Person, Kathleen F. Benson, George D. Eliopoulos

Blood (2003) 101 (7): 2898.

https://doi.org/10.1182/blood-2003-01-0015

Published: 2003

Journal Articles

Mice expressing a neutrophil elastase mutation derived from patients with severe congenital neutropenia have normal granulopoiesis

David S. Grenda, Sonja E. Johnson, Jill R. Mayer, Morgan L. McLemore, Kathleen F. Benson, Marshall Horwitz, Daniel C. Link

Blood (2002) 100 (9): 3221–3228.

https://doi.org/10.1182/blood-2002-05-1372

Published: 2002

Journal Articles

In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis

Joëlle Michaud, Feng Wu, Motomi Osato, Gregory M. Cottles, Masatoshi Yanagida, Norio Asou, Katsuya Shigesada, Yoshiaki Ito, Kathleen F. Benson, Wendy H. Raskind, Colette Rossier, Stylianos E. Antonarakis, Sara Israels, Archie McNicol, Harvey Weiss, Marshall Horwitz, Hamish S. Scott

Blood (2002) 99 (4): 1364–1372.

https://doi.org/10.1182/blood.V99.4.1364

Published: 2002

Journal Articles

Mutations in the gene encoding neutrophil elastase in congenital and cyclic neutropenia

David C. Dale, Richard E. Person, Audrey Anna Bolyard, Andrew G. Aprikyan, Cindy Bos, Mary Ann Bonilla, Laurence A. Boxer, George Kannourakis, Cornelia Zeidler, Karl Welte, Kathleen F. Benson, Marshall Horwitz

Blood (2000) 96 (7): 2317–2322.

https://doi.org/10.1182/blood.V96.7.2317

Published: 2000

NARROW

Neutrophil Elastase Catalytic Activity Regulates Granulopoiesis

Interplay between Inflammatory Microenvironment and RUNX1-Mediated Transcriptomic Changes Drives Defective Hematopoiesis in Familial Platelet Disorder

Conditional Expression of Mutant ELANE Produces Unfolded Protein Response but Fails to Promote Cell Death or Differentiation Block: What Is the Mechanism for Severe Congenital Neutropenia?

Insights from Familial Leukemia and Myelodysplastic Syndromes

Targeted correction Of RUNX1 Mutation In The FPD Patient-Specific Induced Pluripotent Stem Cells Restores Megakaryocytic Differentiation

Neutrophil elastase unleashed

G-CSF receptor mutations mix it up

Acquired Mutation and Reversion of the Neutrophil Elastase Gene, ELA2 , in Kostmann Syndrome and Cyclic Neutropenia Suggest that Some Mutations Cause Neutropenia while Others Paradoxically Suppress It.

Low levels of serum elastase are not associated with mutations in ELA-2 elastase encoding gene in chronic idiopathic neutropenia

Mice expressing a neutrophil elastase mutation derived from patients with severe congenital neutropenia have normal granulopoiesis

In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis

Mutations in the gene encoding neutrophil elastase in congenital and cyclic neutropenia

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American Society of Hematology

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American Society of Hematology

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