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Mahnaz Paktinat
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Journal Articles

The Apc min mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS

Steven W. Lane, Stephen M. Sykes, Fatima Al-Shahrour, Sebastian Shterental, Mahnaz Paktinat, Cristina Lo Celso, Jonathan L. Jesneck, Benjamin L. Ebert, David A. Williams, D. Gary Gilliland
Journal: Blood
Blood (2010) 115 (17): 3489–3497.
https://doi.org/10.1182/blood-2009-11-251728
Published: 2010
Includes: Supplemental data
Journal Articles

Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

Michael G. Kharas, Rachel Okabe, Jared J. Ganis, Maricel Gozo, Tulasi Khandan, Mahnaz Paktinat, D. Gary Gilliland, Kira Gritsman
Journal: Blood
Blood (2010) 115 (7): 1406–1415.
https://doi.org/10.1182/blood-2009-06-229443
Published: 2010
Includes: Supplemental data
Journal Articles

The p110α Catalytic Isoform of PI3 Kinase Is Important for Erythropoiesis, but Has a Minimal Role in Hematopoietic Stem Cell Self-Renewal.

Kira Gritsman, MD, PhD, Tulasi Khandan, Rachel Okabe, Maricel Gozo, Mahnaz Paktinat, D. Gary Gilliland, PhD, MD, Thomas M Roberts, PhD, Jean J. Zhao, PhD
Journal: Blood
Blood (2009) 114 (22): 3620.
https://doi.org/10.1182/blood.V114.22.3620.3620
Published: 2009
Journal Articles

Leukemia Stem Cells Are Resistant to In Vivo, Cell Non-Autonomous Wnt Inhibition.

Steven W. Lane, MD, Cristina Lo Celso, Stephen M Sykes, Sebastian Shterental, Mahnaz Paktinat, Charles P Lin, David A. Williams, MD, David T. Scadden, MD, D. Gary Gilliland, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1025.
https://doi.org/10.1182/blood.V114.22.1025.1025
Published: 2009
Journal Articles

EXEL-8232, a Small Molecule JAK2 Inhibitor, Effectively Treats Thrombocytosis and Extramedullary Hematopoiesis in a Murine Model of Myeloproliferative Disease Induced by MPLW515L

Gerlinde Wernig, Michael G. Kharas, Dena S. Leeman, Rachel Okabe, Maricel Gozo, Mahnaz Paktinat, Erika Haydu, Brian Ball, Tulasi Khandan, Douglas O. Clary, D Gary Gilliland
Journal: Blood
Blood (2008) 112 (11): 3741.
https://doi.org/10.1182/blood.V112.11.3741.3741
Published: 2008