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Gerlinde Wernig
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Journal Articles

Spatial Characterization of Molecular Pathways Suggests the Dysregulation of LGR5 Expressing Fibroblasts in Patients with sclerodermatous Chronic Graft-Vs-Host Disease

Marjia Afrin, Sahar Nasr, Cristabelle De Souza, Brooke Howitt, Antonia Maria Mueller, Sally Arai, Judith Shizuru, Gerlinde Wernig
Journal: Blood
Blood (2024) 144 (Supplement 1): 3536.
https://doi.org/10.1182/blood-2024-211863
Published: 2024
Journal Articles

Multi-Omics Profiling of Skin Biopsies of Patients with Sclerodermatous Graft-Vs-Host Disease Suggests Therapeutic Potential of Targeting Don't Eat Me Signals

Lu Cui, Cristabelle De Souza, Tristan Lerbs, Jessica Poyser, Clarissa Yu, Kerri Rieger, Sally Arai, Ryanne Brown, Judith A Shizuru, Antonia Maria Susanne Müller, Gerlinde Wernig
Journal: Blood
Blood (2022) 140 (Supplement 1): 272–273.
https://doi.org/10.1182/blood-2022-169789
Published: 2022
Journal Articles

Selective Targeting of Immune Modulatory Proteins to Mitigate Fibrosis and Inflammation in Sclerodermatous Graft-Vs-Host Disease

Lu Cui, Cristabelle De Souza, Tristan Lerbs, Jessica Poyser, Maryam Kooshesh, Atif Saleem, Kerri Rieger, Ryanne Brown, Bernice Kwong, Sebastian Fernandez-Pol, Sally Arai, Judith A Shizuru, Antonia MS Mueller, Gerlinde Wernig
Journal: Blood
Blood (2021) 138 (Supplement 1): 644.
https://doi.org/10.1182/blood-2021-151223
Published: 2021
Journal Articles

EXEL-8232, a Small Molecule JAK2 Inhibitor, Effectively Treats Thrombocytosis and Extramedullary Hematopoiesis in a Murine Model of Myeloproliferative Disease Induced by MPLW515L

Gerlinde Wernig, Michael G. Kharas, Dena S. Leeman, Rachel Okabe, Maricel Gozo, Mahnaz Paktinat, Erika Haydu, Brian Ball, Tulasi Khandan, Douglas O. Clary, D Gary Gilliland
Journal: Blood
Blood (2008) 112 (11): 3741.
https://doi.org/10.1182/blood.V112.11.3741.3741
Published: 2008
Journal Articles

High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia

Marc M. Loriaux, Ross L. Levine, Jeffrey W. Tyner, Stefan Fröhling, Claudia Scholl, Eric P. Stoffregen, Gerlinde Wernig, Heidi Erickson, Christopher A. Eide, Roland Berger, Olivier A. Bernard, James D. Griffin, Richard M. Stone, Benjamin Lee, Matthew Meyerson, Michael C. Heinrich, Michael W. Deininger, D. Gary Gilliland, Brian J. Druker
Journal: Blood
Blood (2008) 111 (9): 4788–4796.
https://doi.org/10.1182/blood-2007-07-101394
Published: 2008
Includes: Supplemental data
Journal Articles

The Jak2 V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes

Gerlinde Wernig, Jeffrey R. Gonneville, Brian J. Crowley, Margret S. Rodrigues, Mamatha M. Reddy, Heidi E. Hudon, Christoph Walz, Andreas Reiter, Klaus Podar, Yohan Royer, Stefan N. Constantinescu, Michael H. Tomasson, James D. Griffin, D. Gary Gilliland, Martin Sattler
Journal: Blood
Blood (2008) 111 (7): 3751–3759.
https://doi.org/10.1182/blood-2007-07-102186
Published: 2008
Journal Articles

Efficacy of TG101348, a Selective JAK2 Inhibitor, in Treatment of a Murine Model of JAK2V617F-Induced Polycythemia Vera.

Gerlinde Wernig, MD, Michael G. Kharas, PhD, Rachel Okabe, Sandra A. Moore, Dena S. Leeman, Dana E. Cullen, Maricel Gozo, Elizabeth P. McDowell, Ross L. Levine, John Doukas, Chi Ching Mak, Glenn Noronha, Michael Martin, Yon D. Ko, Benjamin H. Lee, Richard Soll, Ayalew Tefferi, John D. Hood, D. Gary Gilliland
Journal: Blood
Blood (2007) 110 (11): 556.
https://doi.org/10.1182/blood.V110.11.556.556
Published: 2007
Journal Articles

High-Throughput Sequence Analysis of the Tyrosine Kinome in Acute Myeloid Leukemia.

Marc Loriaux, Ross Levine, Jeffrey Tyner, Stephan Frohling, Claudia Scholl, Eric Stoffregen, Gerlinde Wernig, Heidi Erickson, Chris Eide, Roland Berger, Olivier Bernard, James Griffin, Richard Stone, Matthew Meyerson, Michael Heinrich, Michael Deininger, Gary Gilliland, Brian Druker
Journal: Blood
Blood (2007) 110 (11): 886.
https://doi.org/10.1182/blood.V110.11.886.886
Published: 2007
Journal Articles

JAK2 T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model

Thomas Mercher, Gerlinde Wernig, Sandra A. Moore, Ross L. Levine, Ting-Lei Gu, Stefan Fröhling, Dana Cullen, Roberto D. Polakiewicz, Olivier A. Bernard, Titus J. Boggon, Benjamin H. Lee, D. Gary Gilliland
Journal: Blood
Blood (2006) 108 (8): 2770–2779.
https://doi.org/10.1182/blood-2006-04-014712
Published: 2006
Includes: Supplemental data
Journal Articles

Expression of Jak2V617F causes a polycythemia vera–like disease with associated myelofibrosis in a murine bone marrow transplant model

Gerlinde Wernig, Thomas Mercher, Rachel Okabe, Ross L. Levine, Benjamin H. Lee, D. Gary Gilliland
Journal: Blood
Blood (2006) 107 (11): 4274–4281.
https://doi.org/10.1182/blood-2005-12-4824
Published: 2006
Includes: Supplemental data