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Titus J. Boggon
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Journal Articles

Integrated genomic analyses of cutaneous T-cell lymphomas reveal the molecular bases for disease heterogeneity

Joonhee Park, Jay Daniels, Tim Wartewig, Kimberly G. Ringbloom, Maria Estela Martinez-Escala, Sara Choi, Jane J. Thomas, Peter G. Doukas, Jingyi Yang, Caroline Snowden, Calvin Law, Yujin Lee, Katie Lee, Yancong Zhang, Carly Conran, Kyle Tegtmeyer, Samuel H. Mo, David R. Pease, Balaji Jothishankar, Pui-Yan Kwok, Farah R. Abdulla, Barbara Pro, Abner Louissaint, Titus J. Boggon, Jeffrey Sosman, Joan Guitart, Deepak Rao, Jürgen Ruland, Jaehyuk Choi
Journal: Blood
Blood (2021) 138 (14): 1225–1236.
https://doi.org/10.1182/blood.2020009655
Published: 2021
Includes: Supplemental data
Journal Articles

Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E)

Joonhee Park, Jingyi Yang, Alexander T. Wenzel, Akshaya Ramachandran, Wung J. Lee, Jay C. Daniels, Juhyun Kim, Estela Martinez-Escala, Nduka Amankulor, Barbara Pro, Joan Guitart, Marc L. Mendillo, Jeffrey N. Savas, Titus J. Boggon, Jaehyuk Choi
Journal: Blood
Blood (2017) 130 (12): 1430–1440.
https://doi.org/10.1182/blood-2017-02-768234
Published: 2017
Includes: Supplemental data
Journal Articles

Structural and numerical variation of FLT3/ITD in pediatric AML

Brief Report
Soheil Meshinchi, Derek L. Stirewalt, Todd A. Alonzo, Titus J. Boggon, Robert B. Gerbing, Jennifer L. Rocnik, Beverly J. Lange, D. Gary Gilliland, Jerald P. Radich
Journal: Blood
Blood (2008) 111 (10): 4930–4933.
https://doi.org/10.1182/blood-2008-01-117770
Published: 2008
Journal Articles

Identification of Driver and Passenger Mutations of FLT3 by High-Throughput DNA Sequence Analysis and Functional Assessment of Candidate Alleles.

Stefan Frohling, Claudia Scholl, Ross L. Levine, Marc Loriaux, Titus J. Boggon, Olivier A. Bernard, Roland Berger, Hartmut Dohner, Konstanze Dohner, Benjamin L. Ebert, Sewit Teckie, Todd R. Golub, Marcus M. Schittenhelm, Benjamin H. Lee, James D. Griffin, Richard M. Stone, Michael C. Heinrich, Michael W.N. Deininger, Brian J. Druker, D. Gary Gilliland
Journal: Blood
Blood (2007) 110 (11): 206.
https://doi.org/10.1182/blood.V110.11.206.206
Published: 2007
Journal Articles

JAK2 T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model

Thomas Mercher, Gerlinde Wernig, Sandra A. Moore, Ross L. Levine, Ting-Lei Gu, Stefan Fröhling, Dana Cullen, Roberto D. Polakiewicz, Olivier A. Bernard, Titus J. Boggon, Benjamin H. Lee, D. Gary Gilliland
Journal: Blood
Blood (2006) 108 (8): 2770–2779.
https://doi.org/10.1182/blood-2006-04-014712
Published: 2006
Includes: Supplemental data
Journal Articles

Jak3 Kinase Domain Crystal Structures and Implications for Jak-Specific Drug Design.

Titus J. Boggon, PhD
Journal: Blood
Blood (2005) 106 (11): 69.
https://doi.org/10.1182/blood.V106.11.69.69
Published: 2005
Journal Articles

Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog

Titus J. Boggon, Yiqun Li, Paul W. Manley, Michael J. Eck
Journal: Blood
Blood (2005) 106 (3): 996–1002.
https://doi.org/10.1182/blood-2005-02-0707
Published: 2005
Journal Articles

Structural Analysis of Janus Kinases.

Titus J. Boggon, Ph.D., Yiqun Li, Michael J. Eck, M.D. Ph.D.
Journal: Blood
Blood (2004) 104 (11): 3863.
https://doi.org/10.1182/blood.V104.11.3863.3863
Published: 2004
Journal Articles

Identifying and characterizing a novel activating mutation of the FLT3 tyrosine kinase in AML

Clinical Trials & Observations
Jingrui Jiang, J. Guillermo Paez, Jeffrey C. Lee, Ronghai Bo, Richard M. Stone, Daniel J. DeAngelo, Ilene Galinsky, Brian M. Wolpin, Anna Jonasova, Paula Herman, Edward A. Fox, Titus J. Boggon, Michael J. Eck, Ellen Weisberg, James D. Griffin, D. Gary Gilliland, Matthew Meyerson, William R. Sellers
Journal: Blood
Blood (2004) 104 (6): 1855–1858.
https://doi.org/10.1182/blood-2004-02-0712
Published: 2004