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Miguel Gallardo
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Journal Articles

Hnrnpk Overexpression Drives Nucleolar Aberrancies Causing Ribosomopathies

Pedro Aguilar-Garrido, Maria Velasco-Estevez, Miguel Ángel Navarro-Aguadero, María Hernández-Sánchez, Marta Ibáñez-Navarro, Prerna Malaney, Marisa Aitken, Xiaorui Zhang, Adrián Fernández, Alejandra Ortiz-Ruiz, Álvaro Otero-Sobrino, Diego Megías, Manuel Pérez, Jesús Gómez, Gadea Mata, Orlando Domínguez, Osvaldo Graña, Pilar Ximénez, Marta Isasa, Paloma Jimena-de Andrés, Sandra Rodríguez, Raúl Torres, Miguel Lafarga, Oleksandra Sirozh, Vanesa Lafarga, Joaquin Martinez-Lopez, Sean M. Post, Miguel Gallardo
Journal: Blood
Blood (2023) 142 (Supplement 1): 5659.
https://doi.org/10.1182/blood-2023-178022
Published: 2023
Journal Articles

Dynamic Response Assesment Combining Liquid Biopsy MRD and PET/CT in Follicular Lymphoma Patients Including CAR-T Cell Therapy

Alejandro Martín-Muñoz, María Poza, Gloria Figaredo, Sara Dorado, Yanira Ruiz-Heredia, Margarita Rodriguez, Laura Rufian, Antonia Rodriguez Izquierdo, Laura Parrilla-Navamuel, Chongwu Wang, Paula Toledo, Carlos Grande Garcia, Tycho Baumann, Maria Calbacho, Inmaculada Rapado, Miguel Gallardo, Miguel Canales, Pilar Sarandeses, Manuela Mollejo, Luis Felipe Casado Montero, Rosa Ayala, Joaquín Martínez-López, Santiago Barrio, Ana Jimenez-Ubieto
Journal: Blood
Blood (2022) 140 (Supplement 1): 3514–3515.
https://doi.org/10.1182/blood-2022-166372
Published: 2022
Journal Articles

Impaired Death Receptor Signaling Mediates Cross-Resistance to Immunotherapy in MM

Umair Munawar, Xiang Zhou, Sabrina Prommersberger, Max Johannes Steinhardt, Julia Mersi, Max Bittrich, Silvia Nerreter, Cornelia Vogt, Eva Teufel, Seungbin Han, Larissa Haertle, Patrick Eiring, Nicole Banholzer, Sophia Danhof, Adrián Fernández-Martín, Marietta Truger, Santiago Barrio, Miguel Gallardo, Antonio Valeri, Eva Castellano, Peter Raab, Claudia Haferlach, Markus Sauer, Michael Hudecek, Joaquin Martinez-Lopez, Hermann Einsele, Leo Rasche, Martin Kortuem
Journal: Blood
Blood (2022) 140 (Supplement 1): 4226–4227.
https://doi.org/10.1182/blood-2022-168702
Published: 2022
Journal Articles

Potential Utility of Circulating Tumor DNA Monitoring in Primary Mediastinal B-Cell Lymphoma Treated with R-DA-EPOCH

Ana Jimenez-Ubieto, María Poza, Alejandro Martín-Muñoz, Sara Dorado, Yanira Heredia, Pilar Sarandeses, Carmen Bárcena, Laura Rufian, Miguel Canales, Alejandra Juarez, Antonia Rodriguez Izquierdo, Tycho Baumann, Carlos Grande, Ricardo Sanchez, Juan Manuel de la Rosa, Nieves López-Muñoz, Marta Hidalgo, Elena Vera, Miguel Gallardo, Inmaculada Rapado, Rosa Ayala, Joaquín Martínez-López, Santiago Barrio
Journal: Blood
Blood (2021) 138 (Supplement 1): 4491.
https://doi.org/10.1182/blood-2021-152376
Published: 2021
Journal Articles

Minimal Residual Disease Monitoring from Liquid Biopsy By Next Generation Sequencing in Follicular Lymphoma Patients

Ana Isabel Jiminez Ubieto, Yanira Heredia, Juan Manuel de la Rosa, Antonia Rodriguez Izquierdo, Laura Rufian, Jaime Carrillo, Ricardo Sanchez, Esther Onecha, PhD, Chongwu Wang, Pilar Sarandeses, María Poza, MD, Carmen Bárcena, Carlos Grande, Miguel A Canales, MD PhD, Inmaculada Rapado, PhD, Rosa Ayala, Miguel Gallardo, Joaquin Martinez-López, Santiago Barrio
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–33.
https://doi.org/10.1182/blood-2020-139256
Published: 2020
Journal Articles

Increase of Mitochondrial Activity Contributes to the Bortezomib-Relapsed in Multiple Myeloma, a Novel Therapeutic Opportunity

Alejandra Ortiz-Ruiz, BSc, Yanira Ruiz-Heredia, Mehmet Samur, PhD, Pedro Aguilar-Garrido, Maria Luz Morales, Antonio Valeri, PhD, Almudena Garcia-Ortiz, PhD, Santiago Barrio, PhD, Carmen Bárcena, Rosa Maria Garcia-Martin, Vanesa Garrido, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD, María Teresa Cedena, Joaquin Martinez-Lopez, MD PhD, Maria Linares, PhD, Miguel Gallardo, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4408.
https://doi.org/10.1182/blood-2019-123950
Published: 2019
Journal Articles

Clonal Competition Models to Understand Progression and Resistance in Myeloma

Santiago Barrio, PhD, Larissa Haertle, PhD, Umair Munawar, MSc, Lucia Martin, Isabel Cuenca, MSc, Cornelia Vogt, MSc, Andoni Garitano-Trojaola, PhD, Matteo Claudio Da Via', MD, Miguel Gallardo, PhD, Thorsten Stuehmer, PhD, Hermann Einsele, MD, Leo Rasche, MD, Joaquin Martinez-Lopez, MD PhD, Martin Kortüm, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1807.
https://doi.org/10.1182/blood-2019-130812
Published: 2019
Journal Articles

Hierarchy of mono- and biallelic TP53 alterations in multiple myeloma cell fitness

Umair Munawar, Leo Rasche, Nicole Müller, Cornelia Vogt, Matteo Da-Via, Larissa Haertle, Panagiota Arampatzi, Sascha Dietrich, Markus Roth, Andoni Garitano-Trojaola, Maximilian Johannes Steinhardt, Susanne Strifler, Miguel Gallardo, Joaquin Martinez-Lopez, Ralf C. Bargou, Tobias Heckel, Hermann Einsele, Thorsten Stühmer, K. Martin Kortüm, Santiago Barrio
Journal: Blood
Blood (2019) 134 (10): 836–840.
https://doi.org/10.1182/blood.2019000080
Published: 2019
Includes: Supplemental data
Journal Articles

Combination Therapy with BTK Inhibitor Plus Anti-PD-1 Antibody Results in a Hyperprogressor Phenotype in a Mouse Model of CLL

Aidi Gu, PhD, Huaxian Ma, MS, Xiaorui Zhang, BS, Prerna Malaney, PhD, Miguel Gallardo, PhD, Jingwei Liu, MD, Sattva S. Neelapu, MD, Sean M Post, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4416.
https://doi.org/10.1182/blood-2018-99-118773
Published: 2018
Journal Articles

hnRNP K Overexpression Drives Myeloid Malignancy Via Interaction with RUNX1

Marisa J Hornbaker, BS, Prerna Malaney, PhD, Xiaorui Zhang, BS, Ruizhi Duan, M.Sc., Vrutant Shah, PhD, Shelley Herbrich, MS, Miguel Gallardo, PhD, Rodrigo Jacamo, PhD, Todd Link, PhD, Huaxian Ma, MS, Sanzhar Alybayev, MS, Steven M. Kornblau, MD, Peter Hu, PhD, Dos Sarbassov, PhD, Rashmi Kanagal-Shamanna, MD, Carlos E. Bueso-Ramos, MD PhD, Sean M Post, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2622.
https://doi.org/10.1182/blood-2018-99-117387
Published: 2018
Journal Articles

hnRNP K: A Regulator of Global Transcription and Translation That Drives Lymphomagenesis

Prerna Malaney, PhD, Miguel Gallardo, PhD, Marisa J Hornbaker, BS, Xiaorui Zhang, BS, Todd Link, PhD, Vrutant Shah, PhD, Sanzhar Alybayev, MS, Meng-Han Wu, Laura R Pageon, DVM, Huaxian Ma, MS, Rodrigo Jacamo, PhD, Li Yu, MD, Zijun Yidan Xu-Monette, PhD, Haley Steinman, BS, Hun Ju Lee, MD, Dos Sarbassov, PhD, Inmaculada Rapado, Michelle Barton, PhD, Joaquin Martinez-Lopez, MDPhD, Carlos E. Bueso-Ramos, MD PhD, Ken H. Young, MD PhD, Sean M Post, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1346.
https://doi.org/10.1182/blood-2018-99-116163
Published: 2018
Journal Articles

Abnormalities in Mitochondrial DNA Copy Number Have Pathogenetic and Prognostic Implications in Multiple Myeloma

Yanira Ruiz-Heredia, Mehmet Kemal Samur, PhD, Alejandra Ortiz-Ruiz, Rafael Alonso Fernández, Beatriz Sanchez-Vega, Alberto Blazquez, Aitor Delmiro, Jose Carlos Martinez-Avila, Esther Onecha, Antonio Valeri, PhD, Miguel Angel Martin, Niccolo Bolli, MD, Yu-Tzu Tai, PhD, Francesco Maura, Raphael Szalat, MD, Mariateresa Fulciniti, PhD, María Linares, PhD, Miguel Gallardo, PhD, Peter J Campbell, MD PhD, Hervé Avet-Loiseau, Juan Jose Lahuerta, Nikhil Munshi, MD, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4378.
https://doi.org/10.1182/blood.V130.Suppl_1.4378.4378
Published: 2017
Journal Articles

Role of MAX As a Tumor Suppressor Driver Gene in Multiple Myeloma

Santiago Barrio Garcia, PhD, Yanira Ruiz-Heredia, Matteo Da Via', MD, Miguel Gallardo, PhD, Andoni Garitano-Trojaola, PhD, Josip Zovko, MD, Marc S Raab, MD PhD, Pieter Sonneveld, MDPhD, Esteban Braggio, PhD, A. Keith Stewart, MBChB, MBA, Hermann Einsele, Joaquín Martínez, K. Martin Kortüm, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4347.
https://doi.org/10.1182/blood.V130.Suppl_1.4347.4347
Published: 2017
Journal Articles

hnRNP K: A Driver of Myeloid Malignancy

Marisa J Hornbaker, BS, Miguel Gallardo, PhD, Xiaorui Zhang, BS, Prerna Malaney, PhD, Shelley Herbrich, MS, Huaxian Ma, Peter Hu, PhD, Steven Kornblau, MD, Carlos E. Bueso-Ramos, MD PhD, Sean M Post, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2511.
https://doi.org/10.1182/blood.V130.Suppl_1.2511.2511
Published: 2017
Journal Articles

AXL Inhibitor ONO-9330547 Suppresses PLK1 Gene and Protein Expression and Effectively Induces Growth Arrest and Apoptosis in FLT3 ITD Acute Myeloid Leukemia Cells

Peter Ruvolo, PhD, Huaxian Ma, BS, Vivian Ruvolo, MS, Hong Mu, MD PhD, Wendy Schober, Tomoko Yasuhiro, Toshio Yoshizawa, PhD, Miguel Gallardo, PhD, Xiaorui Zhang, BS, Joseph D Khoury, MD, Jorge Cortes, MD, Michael Andreeff, MD PhD, Sean M. Post, PhD
Journal: Blood
Blood (2016) 128 (22): 3939.
https://doi.org/10.1182/blood.V128.22.3939.3939
Published: 2016
Journal Articles

hnRNP K Overexpression Drives AML Progression By Altering Pathways Critical for Myeloid Proliferation and Differentiation

Marisa J Hornbaker, BS, Miguel Gallardo, PhD, Xiaorui Zhang, BS, Huaxian Ma, BS, Peter Hu, PhD, Joseph D Khoury, MD, Steven M. Kornblau, MD, Carlos E Bueso-Ramos, MD PhD, Sean M. Post, PhD
Journal: Blood
Blood (2016) 128 (22): 744.
https://doi.org/10.1182/blood.V128.22.744.744
Published: 2016
Journal Articles

Developing Therapeutic Strategies for CLL with Mutant p53

Hun Ju Lee, MD, Miguel Gallardo, PhD, Xiaorui Zhang, BS, Huaxian Ma, BS, Alfonso Quintas-Cardama, MD, Yuan Qi, Xiaoping Su, PhD, Sean M. Post, PhD
Journal: Blood
Blood (2015) 126 (23): 2476.
https://doi.org/10.1182/blood.V126.23.2476.2476
Published: 2015
Journal Articles

Amplification of hnRNP K Drives c-Myc-Dependent Malignancies and Represent a Novel Therapeutic Opportunity for Hematologic Malignancies

Miguel Gallardo, PhD, Xiaorui Zhang, BS, Mark McArthur, Taghi Manshouri, PhD, Sean M. Post, PhD
Journal: Blood
Blood (2015) 126 (23): 468.
https://doi.org/10.1182/blood.V126.23.468.468
Published: 2015
Journal Articles

hnRNP K Is a Novel Haploinsufficient Tumor Suppressor at the 9q21.32 Locus That Defines a Subset of AML

Miguel Gallardo, PhD, Hun Ju Lee, MD, Xiaorui Zhang, BS, Carlos E. Bueso-Ramos, MD, Laura Pageon, Mark McArthur, Asha Multani, Aziz Nazha, MD, Taghi Manshouri, PhD, Jan Parker-Thornburg, Peter Hu, Yuan Qi, Xiaoping Su, PhD, Inmaculada Rapado, Alfonso Quintás-Cardama, Steven M. Kornblau, MD, Joaquin Martinez-López, MDPhD, Sean M. Post, PhD
Journal: Blood
Blood (2015) 126 (23): 439.
https://doi.org/10.1182/blood.V126.23.439.439
Published: 2015
Journal Articles

hnRNP K Overexpression Synergizes with Mutant NPM1 to Drive Acute Myeloid Leukemia Progression

Miguel Gallardo, PhD, Hun Ju Lee, MD, Xiaorui Zhang, Laura R. Pageon, Asha Multani, Markus Reschke, PhD, John G Clohessy, Alfonso Quintás-Cardama, MD, Michael Andreeff, MD PhD, Steven M. Kornblau, MD, Pier Paolo Pandolfi, MD PhD, Sean M. Post, PhD
Journal: Blood
Blood (2014) 124 (21): 2382.
https://doi.org/10.1182/blood.V124.21.2382.2382
Published: 2014