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Journal Articles

Health-Related Quality-of-Life Improvements after Exagamglogene Autotemcel in Patients with Severe Sickle Cell Disease

Akshay Sharma, Haydar Frangoul, Franco Locatelli, Kevin H.M. Kuo, Monica Bhatia, Markus Y Mapara, Michael J. Eckrich, Suzan Imren, Nanxin Li, Jaime Rubin, Siyu Zhang, Tina Liu, William Hobbs, Stephan A. Grupp

Blood (2024) 144 (Supplement 1): 7453.

https://doi.org/10.1182/blood-2024-204112

Published: 2024

Journal Articles

Durable Clinical Benefits with Exagamglogene Autotemcel for Severe Sickle Cell Disease

Blood (2024) 144 (Supplement 1): 4954.

https://doi.org/10.1182/blood-2024-204001

Published: 2024

Journal Articles

Improvements in Health-Related Quality of Life after Exagamglogene Autotemcel in Patients with Severe Sickle Cell Disease

Akshay Sharma, Haydar Frangoul, Markus Mapara, Suzan Imren, Nanxin Li, Tina Liu, Jaime Rubin, Daoyuan Shi, William Hobbs, Stephan Grupp

Blood (2023) 142 (Supplement 1): 4999.

https://doi.org/10.1182/blood-2023-190203

Published: 2023

Journal Articles

Exagamglogene Autotemcel for Severe Sickle Cell Disease

Blood (2023) 142 (Supplement 1): 1052.

https://doi.org/10.1182/blood-2023-190139

Published: 2023

Journal Articles

VOC-Free Status Among Patients with Sickle Cell Disease Following Allogeneic Hematopoietic Stem Cell Transplant: A Cohort Study of Medicaid Enrollees

Mufaddal Mahesri, Su Been Lee, Raisa Levin, Suzan Imren, Lanju Zhang, Lina Titievsky, Rishi J Desai

Blood (2023) 142 (Supplement 1): 3674.

https://doi.org/10.1182/blood-2023-189427

Published: 2023

Journal Articles

Differing Definitions of Vaso-Occlusion in Clinical Studies of Sickle Cell Disease Can Result in Differing Outcomes

Haydar Frangoul, Suzan Imren, Fengjuan Xuan, Nanxin Li, Jaime Rubin, William Hobbs, Franco Locatelli

Blood (2023) 142 (Supplement 1): 7107.

https://doi.org/10.1182/blood-2023-189246

Published: 2023

Journal Articles

Efficacy and Safety of a Single Dose of Exagamglogene Autotemcel for Severe Sickle Cell Disease

Haydar Frangoul, Franco Locatelli, Monica Bhatia, Markus Y. Mapara, Lyndsay Molinari, Akshay Sharma, Stephan Lobitz, Mariane de Montalembert, Damiano Rondelli, Martin Steinberg, Mark C. Walters, Suzan Imren, Lanju Zhang, Anjali Sharma, Yang Song, Christopher Simard, William Hobbs, Stephen Grupp

Blood (2022) 140 (Supplement 1): 29–31.

https://doi.org/10.1182/blood-2022-162353

Published: 2022

Journal Articles

Safety and Efficacy of CTX001 in Patients with Transfusion-Dependent β-Thalassemia and Sickle Cell Disease: Early Results from the Climb THAL-111 and Climb SCD-121 Studies of Autologous CRISPR-CAS9-Modified CD34+ Hematopoietic Stem and Progenitor Cells

Blood (2020) 136 (Supplement 1): 3–4.

https://doi.org/10.1182/blood-2020-139575

Published: 2020

Journal Articles

CBFA2T3-GLIS2 induces Malignant Transformation of Primitive CD34+ Cord Blood Cells and Recapitulates Infant Megakaryocytic Leukemia

Tiffany A. Hylkema, BS, Laura Pardo, Keith R. Loeb, MD, Quy Le, PhD, Suzan Imren, MD, Lisa Eidenschink Brodersen, PhD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD

Blood (2019) 134 (Supplement_1): 1444.

https://doi.org/10.1182/blood-2019-126185

Published: 2019

Journal Articles

Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML

Blood (2019) 134 (3): 263–276.

https://doi.org/10.1182/blood.2018862383

Published: 2019

Includes: Supplemental data

Journal Articles

Serially Transplantable Patient-Derived Xenograft Model of Chronic Myelomonocytic Leukemia (CMML)

Arnold Kloos, PhD, Felicitas Thol, MD, Lina Winckler, Razif Gabdoulline, PhD, Konstantinos Mintzas, Nidhi Jyotsana, PhD, Renate Schottmann, Felix F. Adams, Adrian Schwarzer, MD PhD, Dirk Heckl, PhD, Suzan Imren, MD, R. Keith Humphries, Arnold Ganser, MD, Michael Heuser, MD

Blood (2017) 130 (Supplement 1): 4236.

https://doi.org/10.1182/blood.V130.Suppl_1.4236.4236

Published: 2017

Journal Articles

Demonstration of Rapid Functional Myeloid Cell Recovery after Infusion of a Universal Donor Ex Vivo Expanded Progenitor Cell Therapy As a Bridging Graft Source

Fabiola V. Merriam, PhD DVM, Suzan Imren, MD, Robert A Landeros, Colleen Delaney, MD MSc

Blood (2016) 128 (22): 3348.

https://doi.org/10.1182/blood.V128.22.3348.3348

Published: 2016

Journal Articles

UV-inactivated HSV-1 potently activates NK cell killing of leukemic cells

Ismael Samudio, Katayoun Rezvani, Hila Shaim, Elyse Hofs, Mor Ngom, Luke Bu, Guoyu Liu, Jason T. C. Lee, Suzan Imren, Vivian Lam, Grace F. T. Poon, Maryam Ghaedi, Fumio Takei, Keith Humphries, William Jia, Gerald Krystal

Blood (2016) 127 (21): 2575–2586.

https://doi.org/10.1182/blood-2015-04-639088

Published: 2016

Includes: Supplemental data

Journal Articles

GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo

Blood (2016) 127 (16): 2018–2027.

https://doi.org/10.1182/blood-2015-11-683649

Published: 2016

Includes: Supplemental data

Journal Articles

Distinct Patterns of Early Hematopoietic Reconstitution in Patients Receiving Notch Expanded Non HLA-Matched Off-the-Shelf Cord Blood Derived Hematopoietic Stem and Progenitor Cells

Jianqiang Li, PhD MSc, Allen Jiang, Filippo Milano, MD PhD, Suzan Imren, MD, David Charles Keahi Oliver, BS, Joseph Blake, Colleen Delaney, MD MSc

Blood (2015) 126 (23): 379.

https://doi.org/10.1182/blood.V126.23.379.379

Published: 2015

Journal Articles

Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13

Suzan Imren, Michael Heuser, Maura Gasparetto, Philip A. Beer, Gudmundur L. Norddahl, Ping Xiang, Ling Chen, Tobias Berg, Garrett W. Rhyasen, Patricia Rosten, Gyeongsin Park, Yeonsook Moon, Andrew P. Weng, Connie J. Eaves, R. Keith Humphries

Blood (2014) 124 (24): 3608–3612.

https://doi.org/10.1182/blood-2014-04-564666

Published: 2014

Includes: Supplemental data

Journal Articles

Short Term Signalling Responses of the Most Primitive Subsets of Human Hematopoietic Cells Stimulated in Vitro Correlate with Their Subsequent Self-Renewal Behaviour.

David J.H.F. Knapp, Sean C. Bendall, PhD, Paul H. Miller, Alice M.S. Cheung, PhD, Suzan Imren, MD, R. Keith Humphries, MD, PhD, Ryan R. Brinkman, Robert A.J. Oostendorp, BSc, MSc, PhD, Garry P. Nolan, PhD, Connie J. Eaves, PhD

Blood (2012) 120 (21): 2341.

https://doi.org/10.1182/blood.V120.21.2341.2341

Published: 2012

Journal Articles

Distinct Human Cell Populations Produce Rapidly Detectable Levels of Neutrophils and Platelets in NOD/SCID-IL-2Receptor Gamma Chain Null Mice Transgenically Engineered to Produce Human Myeloid Growth Factors

Paul H. Miller, Alice M.S. Cheung, PhD, Suzan Imren, MD, Philip A Beer, BM, MRCP, MRCPath, Shabnam Rostamirad, Kiran Dhillon, R. Keith Humphries, MD, PhD, Connie J. Eaves, PhD

Blood (2011) 118 (21): 1892.

https://doi.org/10.1182/blood.V118.21.1892.1892

Published: 2011

Journal Articles

In Vitro Expansion of Human Hematopoietic Cells with Delayed but Sustained Multi-Lineage Repopulating Activity

Alice M.S. Cheung, PhD, Stefan Wohrer, MD, Paul H. Miller, Suzan Imren, MD, Shabnam Rostamirad, Kiran Dhillon, David Knapp, Robert A.J. Oostendorp, BSc, MSc, PhD, R. Keith Humphries, MD, PhD, Connie J. Eaves, PhD

Blood (2011) 118 (21): 1270.

https://doi.org/10.1182/blood.V118.21.1270.1270

Published: 2011

Journal Articles

Enhancement of Soluble Transcription Factor (TAT-HOXB4 and TAT-NUP98HOXA10HD) - Mediated Human Hematopoietic Stem Cell Self-Renewal by Minimizing Inhibitory Endogenous Signalling.

Elizabeth Csaszar, Daniel Kirouac, Genevieve Gavigan, Suzan Imren, MD, Michelle Miller, R. Keith Humphries, MD, PhD, Peter W. Zandstra, PhD

Blood (2009) 114 (22): 1493.

https://doi.org/10.1182/blood.V114.22.1493.1493

Published: 2009

NARROW

Health-Related Quality-of-Life Improvements after Exagamglogene Autotemcel in Patients with Severe Sickle Cell Disease

Durable Clinical Benefits with Exagamglogene Autotemcel for Severe Sickle Cell Disease

Improvements in Health-Related Quality of Life after Exagamglogene Autotemcel in Patients with Severe Sickle Cell Disease

Exagamglogene Autotemcel for Severe Sickle Cell Disease

VOC-Free Status Among Patients with Sickle Cell Disease Following Allogeneic Hematopoietic Stem Cell Transplant: A Cohort Study of Medicaid Enrollees

Differing Definitions of Vaso-Occlusion in Clinical Studies of Sickle Cell Disease Can Result in Differing Outcomes

Efficacy and Safety of a Single Dose of Exagamglogene Autotemcel for Severe Sickle Cell Disease

Safety and Efficacy of CTX001 in Patients with Transfusion-Dependent β-Thalassemia and Sickle Cell Disease: Early Results from the Climb THAL-111 and Climb SCD-121 Studies of Autologous CRISPR-CAS9-Modified CD34+ Hematopoietic Stem and Progenitor Cells

CBFA2T3-GLIS2 induces Malignant Transformation of Primitive CD34+ Cord Blood Cells and Recapitulates Infant Megakaryocytic Leukemia

Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML

Serially Transplantable Patient-Derived Xenograft Model of Chronic Myelomonocytic Leukemia (CMML)

Demonstration of Rapid Functional Myeloid Cell Recovery after Infusion of a Universal Donor Ex Vivo Expanded Progenitor Cell Therapy As a Bridging Graft Source

UV-inactivated HSV-1 potently activates NK cell killing of leukemic cells

GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo

Distinct Patterns of Early Hematopoietic Reconstitution in Patients Receiving Notch Expanded Non HLA-Matched Off-the-Shelf Cord Blood Derived Hematopoietic Stem and Progenitor Cells

Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13

Short Term Signalling Responses of the Most Primitive Subsets of Human Hematopoietic Cells Stimulated in Vitro Correlate with Their Subsequent Self-Renewal Behaviour.

Distinct Human Cell Populations Produce Rapidly Detectable Levels of Neutrophils and Platelets in NOD/SCID-IL-2Receptor Gamma Chain Null Mice Transgenically Engineered to Produce Human Myeloid Growth Factors

In Vitro Expansion of Human Hematopoietic Cells with Delayed but Sustained Multi-Lineage Repopulating Activity

Enhancement of Soluble Transcription Factor (TAT-HOXB4 and TAT-NUP98HOXA10HD) - Mediated Human Hematopoietic Stem Cell Self-Renewal by Minimizing Inhibitory Endogenous Signalling.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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