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Journal Articles

Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics

Blood (2023) 142 (Supplement 1): 163.

https://doi.org/10.1182/blood-2023-186367

Published: 2023

Journal Articles

Disruption of Intracellular Metal Homeostasis As a Vulnerability in SF3B1 Mutated AML

Céline Moison, Deanne Gracias, Julie Schmitt, Simon Girard, Simon Fortier, Isabel Boivin, Jean-Francois Spinella, Tara Macrae, Rejean Ruel, Josee Hebert, Anne Marinier, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 10680–10681.

https://doi.org/10.1182/blood-2022-165235

Published: 2022

Journal Articles

Identification of Novel Antigens for Normal Karyotype Triple Mutated Acute Myeloid Leukemia

Arnaud Metois, Marie-Eve Bordeleau, Louis Theret, Azadeh Hajmirza, Ossama Moujaber, Jean-François Spinella, Jalila Chagraoui, Nadine Mayotte, Isabel Boivin, Eric Audemard, Azer Farah, Véronique Lisi, Eric Bonneil, Pierre Thibault, Guillaume Richard-Carpentier, Vincent-Philippe Lavallée, Josee Hebert, Philippe P Roux, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 11791–11792.

https://doi.org/10.1182/blood-2022-166857

Published: 2022

Journal Articles

Identification of Novel Cell Surface Therapeutic Targets for KMT2A -Rearranged Acute Myeloid Leukemia

Blood (2022) 140 (Supplement 1): 6316–6317.

https://doi.org/10.1182/blood-2022-166769

Published: 2022

Journal Articles

HLF expression defines the human hematopoietic stem cell state

Bernhard Lehnertz, Jalila Chagraoui, Tara MacRae, Elisa Tomellini, Sophie Corneau, Nadine Mayotte, Isabel Boivin, Aurélie Durand, Deanne Gracias, Guy Sauvageau

Blood (2021) 138 (25): 2642–2654.

https://doi.org/10.1182/blood.2021010745

Published: 2021

Includes: Supplemental data

Journal Articles

High frequency of germline RUNX1 mutations in patients with RUNX1 -mutated AML

Laura Simon, Jean-François Spinella, Chi-Yuan Yao, Vincent-Philippe Lavallée, Isabel Boivin, Geneviève Boucher, Eric Audemard, Marie-Eve Bordeleau, Sébastien Lemieux, Josée Hébert, Guy Sauvageau

Blood (2020) 135 (21): 1882–1886.

https://doi.org/10.1182/blood.2019003357

Published: 2020

Includes: Supplemental data

Journal Articles

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 910.

https://doi.org/10.1182/blood-2018-99-114525

Published: 2018

Journal Articles

Chemogenomic Profiling of Complex Karyotype AML Reveals a Novel Susceptibility to G2/M Checkpoint Inhibition Mediated By HMGA2 Overexpression

Céline Moison, PhD, Vincent-Philippe Lavallee, MD, Clarisse Thiollier, PhD, Jean-Francois Spinella, PhD, Isabel Boivin, Sébastien Lemieux, PhD, Anne Marinier, PhD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 3925.

https://doi.org/10.1182/blood-2018-99-111304

Published: 2018

Journal Articles

Genetic Characterization of ABT-199 Sensitivity in Human AML

Marie-Eve Bordeleau, PhD, Richard Bisaillon, PhD, Clarisse Thiollier, PhD, Jana Krosl, PhD, Bernhard Lehnertz, PhD, Vincent-Philippe Lavallee, MD, Tara MacRae, Labelle Caroline, Geneviève Boucher, Isabel Boivin, Giovanni D'Angelo, Sylvie Lavallée, Anne Marinier, PhD, Sébastien Lemieux, PhD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 283.

https://doi.org/10.1182/blood-2018-99-113062

Published: 2018

Journal Articles

H3K27M/I Mutations Promote Context-Dependent Transformation in Acute Myeloid Leukemia with RUNX1 Alterations

Bernhard Lehnertz, PhD, Yu Wei Zhang, Isabel Boivin, Nadine Mayotte, Tomellini Elisa, PhD, Jalila Chagraoui, PhD, Vincent-Philippe Lavallée, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2017) 130 (Supplement 1): 302.

https://doi.org/10.1182/blood.V130.Suppl_1.302.302

Published: 2017

Journal Articles

H3 K27M/I mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations

Bernhard Lehnertz, Yu Wei Zhang, Isabel Boivin, Nadine Mayotte, Elisa Tomellini, Jalila Chagraoui, Vincent-Philippe Lavallée, Josée Hébert, Guy Sauvageau

Blood (2017) 130 (20): 2204–2214.

https://doi.org/10.1182/blood-2017-03-774653

Published: 2017

Includes: Supplemental data

Journal Articles

Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease

Vincent-Philippe Lavallée, MD, Miriam Marquis, PhD, Marie-Ève Bordeleau, PhD, Jalila Chagraoui, PhD, Tara MacRae, M.Sc., Isabel Boivin, M.Sc, Geneviève Boucher, M.Sc, Patrick Gendron, M.Sc, Sébastien Lemieux, PhD, Arnaud Bonnefoy, PhD, Georges E. Rivard, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2016) 128 (22): 1075.

https://doi.org/10.1182/blood.V128.22.1075.1075

Published: 2016

Journal Articles

Chemo-Transcriptomic Analysis of Complex Karyotype AML Reveals Increased Expression of Cell Cycle Components and Exquisite Dependency on Polo-like Kinase 1

Vincent-Philippe Lavallée, MD, Clarisse Thiollier, PhD, Céline Moison, PhD, Marie-Ève Bordeleau, PhD, Isabel Boivin, M.Sc, Geneviève Boucher, M.Sc, Patrick Gendron, M.Sc, Sébastien Lemieux, PhD, Anne Marinier, PhD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2016) 128 (22): 769.

https://doi.org/10.1182/blood.V128.22.769.769

Published: 2016

Journal Articles

Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors

Vincent-Philippe Lavallée, Jana Krosl, Sébastien Lemieux, Geneviève Boucher, Patrick Gendron, Caroline Pabst, Isabel Boivin, Anne Marinier, Cynthia J. Guidos, Sylvain Meloche, Josée Hébert, Guy Sauvageau

Blood (2016) 127 (24): 3054–3061.

https://doi.org/10.1182/blood-2016-03-705053

Published: 2016

Includes: Supplemental data

Journal Articles

RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature

Vincent-Philippe Lavallée, Sébastien Lemieux, Geneviève Boucher, Patrick Gendron, Isabel Boivin, Richard N. Armstrong, Guy Sauvageau, Josée Hébert

Blood (2016) 127 (20): 2498–2501.

https://doi.org/10.1182/blood-2016-03-703868

Published: 2016

Includes: Supplemental data

Journal Articles

GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo

Blood (2016) 127 (16): 2018–2027.

https://doi.org/10.1182/blood-2015-11-683649

Published: 2016

Includes: Supplemental data

Journal Articles

Mutational and Transcriptomic Landscape of AML with Core-Binding Factor Rearrangements

Vincent-Philippe Lavallée, MD, Patrick Gendron, M.Sc, Geneviève Boucher, M.Sc, Sébastien Lemieux, PhD, Richard Neil Armstrong, PhD, Isabel Boivin, M.Sc, Guy Sauvageau, MD, PhD, Josée Hébert, MD

Blood (2015) 126 (23): 802.

https://doi.org/10.1182/blood.V126.23.802.802

Published: 2015

NARROW

Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics

Disruption of Intracellular Metal Homeostasis As a Vulnerability in SF3B1 Mutated AML

Identification of Novel Antigens for Normal Karyotype Triple Mutated Acute Myeloid Leukemia

Identification of Novel Cell Surface Therapeutic Targets for KMT2A -Rearranged Acute Myeloid Leukemia

HLF expression defines the human hematopoietic stem cell state

High frequency of germline RUNX1 mutations in patients with RUNX1 -mutated AML

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Chemogenomic Profiling of Complex Karyotype AML Reveals a Novel Susceptibility to G2/M Checkpoint Inhibition Mediated By HMGA2 Overexpression

Genetic Characterization of ABT-199 Sensitivity in Human AML

H3K27M/I Mutations Promote Context-Dependent Transformation in Acute Myeloid Leukemia with RUNX1 Alterations

H3 K27M/I mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations

Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease

Chemo-Transcriptomic Analysis of Complex Karyotype AML Reveals Increased Expression of Cell Cycle Components and Exquisite Dependency on Polo-like Kinase 1

Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors

RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature

GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo

Mutational and Transcriptomic Landscape of AML with Core-Binding Factor Rearrangements

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American Society of Hematology

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American Society of Hematology

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