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Journal Articles

KBTBD4-mediated reduction of MYC is critical for hematopoietic stem cell expansion upon UM171 treatment

Jalila Chagraoui, Simon Girard, Laure Mallinger, Nadine Mayotte, Maria Florencia Tellechea, Guy Sauvageau

Blood (2024) 143 (10): 882–894.

https://doi.org/10.1182/blood.2023021342

Published: 2024

Includes: Supplemental data

Journal Articles

Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics

Blood (2023) 142 (Supplement 1): 163.

https://doi.org/10.1182/blood-2023-186367

Published: 2023

Journal Articles

Deciphering the Boundaries of KBTBD4-CoREST1 Axis Modulation to Maximally Expand Human HSCs

Maria Florencia Florencia Tellechea, Jalila Chagraoui, Nadine Mayotte, Guy Sauvageau

Blood (2023) 142 (Supplement 1): 2681.

https://doi.org/10.1182/blood-2023-189646

Published: 2023

Journal Articles

Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia

Azadeh Hajmirza, Laura Simon, Jalila Chagraoui, Nadine Mayotte, Jean-François Spinella, Tara Macrae, Bernhard Lehnertz, Thierry Bertomeu, Jasmin Coulombe-Huntington, Geneviève Boucher, Sébastien Lemieux, Mike Tyers, Josee Hebert, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 8825–8826.

https://doi.org/10.1182/blood-2022-163685

Published: 2022

Journal Articles

Identification of Novel Antigens for Normal Karyotype Triple Mutated Acute Myeloid Leukemia

Arnaud Metois, Marie-Eve Bordeleau, Louis Theret, Azadeh Hajmirza, Ossama Moujaber, Jean-François Spinella, Jalila Chagraoui, Nadine Mayotte, Isabel Boivin, Eric Audemard, Azer Farah, Véronique Lisi, Eric Bonneil, Pierre Thibault, Guillaume Richard-Carpentier, Vincent-Philippe Lavallée, Josee Hebert, Philippe P Roux, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 11791–11792.

https://doi.org/10.1182/blood-2022-166857

Published: 2022

Journal Articles

Identification of Novel Cell Surface Therapeutic Targets for KMT2A -Rearranged Acute Myeloid Leukemia

Blood (2022) 140 (Supplement 1): 6316–6317.

https://doi.org/10.1182/blood-2022-166769

Published: 2022

Journal Articles

HLF expression defines the human hematopoietic stem cell state

Bernhard Lehnertz, Jalila Chagraoui, Tara MacRae, Elisa Tomellini, Sophie Corneau, Nadine Mayotte, Isabel Boivin, Aurélie Durand, Deanne Gracias, Guy Sauvageau

Blood (2021) 138 (25): 2642–2654.

https://doi.org/10.1182/blood.2021010745

Published: 2021

Includes: Supplemental data

Journal Articles

UM171-Expanded Cord Blood Transplants Support Robust T-Cell Reconstitution with Low Rates of Severe Infections

Blood (2020) 136 (Supplement 1): 36–37.

https://doi.org/10.1182/blood-2020-139598

Published: 2020

Journal Articles

Coordination of Pro- and Anti-Inflammatory Signals Determine Human Hematopoietic Stem and Progenitor Cell Expansion

Jalila Chagraoui, PhD, Elisa Tomellini, PhD, Leo Aubert, Iman Fares, PhD, Jean-Francois Spinella, PhD, Simon Girard, Nadine Mayotte, Philippe P Roux, PhD, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 2555.

https://doi.org/10.1182/blood-2018-99-111917

Published: 2018

Journal Articles

Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1 -Mutated AML to Glucocorticoids

Laura Simon, BSc, MSc, Vincent-Philippe Lavallee, MD, Marie-Eve Bordeleau, PhD, Bernhard Lehnertz, PhD, Tara MacRae, Jalila Chagraoui, PhD, Jean-Francois Spinella, PhD, Geneviève Boucher, Thierry Bertomeu, PhD, Jasmin Coulombe-Huntington, PhD, Mike Tyers, PhD, Sébastien Lemieux, PhD, Anne Marinier, PhD, Josée Hébert, MD, Guy Sauvageau, MD PhD

Blood (2018) 132 (Supplement 1): 4675.

https://doi.org/10.1182/blood-2018-99-111030

Published: 2018

Journal Articles

Single UM171 Expanded Cord Blood Permits Transplantation of Better HLA Matched Cords with Excellent Gvhd Relapse Free Survival

Blood (2018) 132 (Supplement 1): 4658.

https://doi.org/10.1182/blood-2018-99-110188

Published: 2018

Journal Articles

Integrin-α3 Is a New Marker of Long-Term Hematopoietic Stem Cells in Ex Vivo Expanded Cells

Elisa Tomellini, PhD, Iman Fares, PhD, Bernhard Lehnertz, PhD, Jalila Chagraoui, PhD, Nadine Mayotte, Tara MacRae, Sophie Corneau, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 1267.

https://doi.org/10.1182/blood-2018-99-111963

Published: 2018

Journal Articles

H3K27M/I Mutations Promote Context-Dependent Transformation in Acute Myeloid Leukemia with RUNX1 Alterations

Bernhard Lehnertz, PhD, Yu Wei Zhang, Isabel Boivin, Nadine Mayotte, Tomellini Elisa, PhD, Jalila Chagraoui, PhD, Vincent-Philippe Lavallée, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2017) 130 (Supplement 1): 302.

https://doi.org/10.1182/blood.V130.Suppl_1.302.302

Published: 2017

Journal Articles

Podoplanin Expression in the Bleeding Complications of Acute Promyelocytic Leukemias

Vincent-Philippe Lavallee, MD, Jalila Chagraoui, PhD, MacRae Tara, M.Sc., Miriam Marquis, PhD, Bonnefoy Arnaud, PhD, Jana Krosl, PhD, Sébastien Lemieux, PhD, Georges-Étienne Rivard, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2017) 130 (Supplement 1): 105.

https://doi.org/10.1182/blood.V130.Suppl_1.105.105

Published: 2017

Journal Articles

H3 K27M/I mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations

Bernhard Lehnertz, Yu Wei Zhang, Isabel Boivin, Nadine Mayotte, Elisa Tomellini, Jalila Chagraoui, Vincent-Philippe Lavallée, Josée Hébert, Guy Sauvageau

Blood (2017) 130 (20): 2204–2214.

https://doi.org/10.1182/blood-2017-03-774653

Published: 2017

Includes: Supplemental data

Journal Articles

EPCR expression marks UM171-expanded CD34 + cord blood stem cells

Iman Fares, Jalila Chagraoui, Bernhard Lehnertz, Tara MacRae, Nadine Mayotte, Elisa Tomellini, Léo Aubert, Philippe P. Roux, Guy Sauvageau

Blood (2017) 129 (25): 3344–3351.

https://doi.org/10.1182/blood-2016-11-750729

Published: 2017

Includes: Supplemental data

Journal Articles

Modeling of Pediatric Acute Megakaryoblastic Leukemia Using Cord Blood Stem/Progenitor Cells

Sophie Cardin, PhD, Louise Laramee, Tara MacRae, M.Sc., Jalila Chagraoui, PhD, Guy Sauvageau, MD PhD, R. Keith Humphries, MD PhD, Josée Hébert, MD, Brian T. Wilhelm, PhD, Sonia Cellot, MD PhD

Blood (2016) 128 (22): 1535.

https://doi.org/10.1182/blood.V128.22.1535.1535

Published: 2016

Journal Articles

Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease

Vincent-Philippe Lavallée, MD, Miriam Marquis, PhD, Marie-Ève Bordeleau, PhD, Jalila Chagraoui, PhD, Tara MacRae, M.Sc., Isabel Boivin, M.Sc, Geneviève Boucher, M.Sc, Patrick Gendron, M.Sc, Sébastien Lemieux, PhD, Arnaud Bonnefoy, PhD, Georges E. Rivard, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2016) 128 (22): 1075.

https://doi.org/10.1182/blood.V128.22.1075.1075

Published: 2016

Journal Articles

Targeting Pre-Leukemic Stem Cells in T-Acute Lymphoblastic Leukemia

Blood (2016) 128 (22): 527.

https://doi.org/10.1182/blood.V128.22.527.527

Published: 2016

Journal Articles

UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity

Marie-Eve Bordeleau, Romain Aucagne, Jalila Chagraoui, Simon Girard, Nadine Mayotte, Éric Bonneil, Pierre Thibault, Caroline Pabst, Anne Bergeron, Frédéric Barabé, Josée Hébert, Martin Sauvageau, Christel Boutonnet, Sylvain Meloche, Guy Sauvageau

Blood (2014) 124 (15): 2362–2369.

https://doi.org/10.1182/blood-2014-01-548651

Published: 2014

Includes: Supplemental data

NARROW

KBTBD4-mediated reduction of MYC is critical for hematopoietic stem cell expansion upon UM171 treatment

Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics

Deciphering the Boundaries of KBTBD4-CoREST1 Axis Modulation to Maximally Expand Human HSCs

Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia

Identification of Novel Antigens for Normal Karyotype Triple Mutated Acute Myeloid Leukemia

Identification of Novel Cell Surface Therapeutic Targets for KMT2A -Rearranged Acute Myeloid Leukemia

HLF expression defines the human hematopoietic stem cell state

UM171-Expanded Cord Blood Transplants Support Robust T-Cell Reconstitution with Low Rates of Severe Infections

Coordination of Pro- and Anti-Inflammatory Signals Determine Human Hematopoietic Stem and Progenitor Cell Expansion

Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1 -Mutated AML to Glucocorticoids

Single UM171 Expanded Cord Blood Permits Transplantation of Better HLA Matched Cords with Excellent Gvhd Relapse Free Survival

Integrin-α3 Is a New Marker of Long-Term Hematopoietic Stem Cells in Ex Vivo Expanded Cells

H3K27M/I Mutations Promote Context-Dependent Transformation in Acute Myeloid Leukemia with RUNX1 Alterations

Podoplanin Expression in the Bleeding Complications of Acute Promyelocytic Leukemias

H3 K27M/I mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations

EPCR expression marks UM171-expanded CD34 + cord blood stem cells

Modeling of Pediatric Acute Megakaryoblastic Leukemia Using Cord Blood Stem/Progenitor Cells

Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease

Targeting Pre-Leukemic Stem Cells in T-Acute Lymphoblastic Leukemia

UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity

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American Society of Hematology

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ASH Publications

American Society of Hematology

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