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Claudio Martines
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Journal Articles

CXCR4 Loss Reduces the Local Growth of Richter Syndrome Murine and Patient-Derived Xenograft Models and Impairs BCR and VLA-4 Activation

Claudio Martines, Supriya Chakraborty, Antonella Zucchetto, Erika Tissino, Vincenzo Guastafierro, Marija Vujovikj, Tiziana Vaisitti, Silvia Deaglio, Luca Laurenti, Aleksandar J Dimovski, Valter Gattei, Dimitar G Efremov
Journal: Blood
Blood (2023) 142 (Supplement 1): 80.
https://doi.org/10.1182/blood-2023-179183
Published: 2023
Journal Articles

Macrophage- and BCR-derived but not TLR-derived signals support the growth of CLL and Richter syndrome murine models in vivo

Claudio Martines, Supriya Chakraborty, Marija Vujovikj, Stefania Gobessi, Tiziana Vaisitti, Silvia Deaglio, Luca Laurenti, Aleksandar J. Dimovski, Dimitar G. Efremov
Journal: Blood
Blood (2022) 140 (22): 2335–2347.
https://doi.org/10.1182/blood.2022016272
Published: 2022
Includes: Supplemental data
Journal Articles

Rapid Generation of Murine CLL/Richter Syndrome Models By Multiplexed CRISPR/Cas9 Editing of Common CLL Driver Genes

Supriya Chakraborty, Giulia Felician, Claudio Martines, Alice Bonato, Ana Colado, Marija Vujovic, Aleksandar J. Dimovski, Dimitar G Efremov
Journal: Blood
Blood (2022) 140 (Supplement 1): 1536–1537.
https://doi.org/10.1182/blood-2022-163067
Published: 2022
Journal Articles

Chronic Lymphocytic Leukemia Cells with Mutated Nfkbie Are Positively Selected By Microenvironmental Signals and Display Reduced Sensitivity to Ibrutinib Treatment

Alice Bonato, Riccardo Bomben, Supriya Chakraborty, Giulia Felician, Claudio Martines, Antonella Zucchetto, Annalisa Chiarenza, Giovanni Del Poeta, Roberto Marasca, Agostino Tafuri, Luca Laurenti, Aleksandar J. Dimovski, Valter Gattei, Dimitar G Efremov
Journal: Blood
Blood (2021) 138 (Supplement 1): 248.
https://doi.org/10.1182/blood-2021-149442
Published: 2021
Journal Articles

B-cell receptor signaling and genetic lesions in TP53 and CDKN2A/CDKN2B cooperate in Richter transformation

Supriya Chakraborty, Claudio Martines, Fabiola Porro, Ilaria Fortunati, Alice Bonato, Marija Dimishkovska, Silvano Piazza, Brijesh S. Yadav, Idanna Innocenti, Rosa Fazio, Tiziana Vaisitti, Silvia Deaglio, Alberto Zamò, Aleksandar J. Dimovski, Luca Laurenti, Dimitar G. Efremov
Journal: Blood
Blood (2021) 138 (12): 1053–1066.
https://doi.org/10.1182/blood.2020008276
Published: 2021
Includes: Supplemental data
Journal Articles

Combined Genetic Lesions in TP53 and CDKN2A/CDKN2B Drive B Cell Receptor-Dependent/Costimulatory Signal-Independent Proliferation in Richter Syndrome

Supriya Chakraborty, PhD, Claudio Martines, MS, Fabiola Porro, MS, Ilaria Fortunati, BS, Alice Bonato, BA, Marija Dimishkovska, PhD, Brijesh Yadav, PhD, Idanna Innocenti, MDPhD, Rosa Fazio, BA, Tizianna Vaisitti, PhD, Silvia Deaglio, MD, Alberto Zamò, MD PhD, Aleksandar Dimovski, MD PhD, Luca Laurenti, MD, Dimitar G Efremov, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-136668
Published: 2020
Journal Articles

A CRISPR/Cas9-Generated Murine Model Reveals Cooperation between BCR Signaling and CDKN2A/2B and TP53 Disruption in Richter Syndrome

Supriya Chakraborty, PhD, Ilaria Fortunati, BS, Claudio Martines, MS, Brijesh Yadav, PhD, Marija Dimishkovska, PhD, Idanna Innocenti, MD PhD, Rosa Fazio, BS, Giovanni D'Arena, MD, Aleksandar Dimovski, MD PhD, Luca Laurenti, MD, Dimitar G Efremov, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4278.
https://doi.org/10.1182/blood-2019-128425
Published: 2019
Journal Articles

Serum IgM/Fcmr Interactions Inhibit BCR Signaling and Influence the Cinical Course of CLL

Stefania Gobessi, PhD, Luca Laurenti, MD, Fabiola Porro, MS, Claudio Martines, MS, Rosa Fazio, BS, Elena Xerxa, PhD, Idanna Innocenti, MD PhD, Antonella Zucchetto, Shih-Shih Chen, PhD, Xiao-Jie Yan, MD PhD, Nicholas Chiorazzi, MD, Valter Gattei, MD, Dimitar G Efremov, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4409.
https://doi.org/10.1182/blood-2018-99-118562
Published: 2018