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Journal Articles

Richter Syndrome-Associated Genetic Lesions in TP53 and the Cell Cycle Inhibitors CDKN2A and CDKN2B Induce Transformation of a CD5+ B Cell Subset Characterized By a Restricted IGHV Repertoire, Autoreactivity and BCR Dependence

Claudio Martines, Supriya Chakraborty, Giulia Felician, Karin Hofmann, Sasha Blasutig, Ivan Negara, Alice Bonato, Marija Vujovikj, Alberto Zamò, Andreas Rosenwald, Aleksandar J Dimovski, Dimitar G Efremov

Blood (2024) 144 (Supplement 1): 759.

https://doi.org/10.1182/blood-2024-207095

Published: 2024

Journal Articles

CXCR4 Loss Reduces the Local Growth of Richter Syndrome Murine and Patient-Derived Xenograft Models and Impairs BCR and VLA-4 Activation

Claudio Martines, Supriya Chakraborty, Antonella Zucchetto, Erika Tissino, Vincenzo Guastafierro, Marija Vujovikj, Tiziana Vaisitti, Silvia Deaglio, Luca Laurenti, Aleksandar J Dimovski, Valter Gattei, Dimitar G Efremov

Blood (2023) 142 (Supplement 1): 80.

https://doi.org/10.1182/blood-2023-179183

Published: 2023

Journal Articles

Macrophage- and BCR-derived but not TLR-derived signals support the growth of CLL and Richter syndrome murine models in vivo

Claudio Martines, Supriya Chakraborty, Marija Vujovikj, Stefania Gobessi, Tiziana Vaisitti, Silvia Deaglio, Luca Laurenti, Aleksandar J. Dimovski, Dimitar G. Efremov

Blood (2022) 140 (22): 2335–2347.

https://doi.org/10.1182/blood.2022016272

Published: 2022

Includes: Supplemental data

Journal Articles

Rapid Generation of Murine CLL/Richter Syndrome Models By Multiplexed CRISPR/Cas9 Editing of Common CLL Driver Genes

Supriya Chakraborty, Giulia Felician, Claudio Martines, Alice Bonato, Ana Colado, Marija Vujovic, Aleksandar J. Dimovski, Dimitar G Efremov

Blood (2022) 140 (Supplement 1): 1536–1537.

https://doi.org/10.1182/blood-2022-163067

Published: 2022

Journal Articles

Prevalence of Allelic Variants and Clonality of IGHV1-69 Expressing B-Cells in Patients with Different Severity of COVID 19 Disease

Irina Panovska-Stavridis, Nevenka Ridova, Simona Stojanovska, Milena Stevanovic, Tatjana Stojanoska, Ilir Demiri, Nadica Matevska-Geshkovska, Marija Vujovic, Hristina Markoska, Venko Filipce, Aleksandar J. Dimovski, Dimitar G Efremov

Blood (2021) 138 (Supplement 1): 994.

https://doi.org/10.1182/blood-2021-153487

Published: 2021

Journal Articles

Chronic Lymphocytic Leukemia Cells with Mutated Nfkbie Are Positively Selected By Microenvironmental Signals and Display Reduced Sensitivity to Ibrutinib Treatment

Alice Bonato, Riccardo Bomben, Supriya Chakraborty, Giulia Felician, Claudio Martines, Antonella Zucchetto, Annalisa Chiarenza, Giovanni Del Poeta, Roberto Marasca, Agostino Tafuri, Luca Laurenti, Aleksandar J. Dimovski, Valter Gattei, Dimitar G Efremov

Blood (2021) 138 (Supplement 1): 248.

https://doi.org/10.1182/blood-2021-149442

Published: 2021

Journal Articles

B-cell receptor signaling and genetic lesions in TP53 and CDKN2A/CDKN2B cooperate in Richter transformation

Supriya Chakraborty, Claudio Martines, Fabiola Porro, Ilaria Fortunati, Alice Bonato, Marija Dimishkovska, Silvano Piazza, Brijesh S. Yadav, Idanna Innocenti, Rosa Fazio, Tiziana Vaisitti, Silvia Deaglio, Alberto Zamò, Aleksandar J. Dimovski, Luca Laurenti, Dimitar G. Efremov

Blood (2021) 138 (12): 1053–1066.

https://doi.org/10.1182/blood.2020008276

Published: 2021

Includes: Supplemental data

Journal Articles

Correlation of Somatic Mutations and Clinical Characteristics at Presentation in Patients with Essential Thrombocytemia

Aleksandar Eftimov, Mr Pharm, Irina Panovska-Stavridis, MD, Marija Popova-Simjanovska, MD, Martin Ivanovski, MD, Aleksandar Stojanovic, MDPhD, Lidija Cevreska, MDPhD, Nadica Geshkovska Matevska, Mr.Sci, Aleksandar J Dimovski, MDPhD

Blood (2014) 124 (21): 5582.

https://doi.org/10.1182/blood.V124.21.5582.5582

Published: 2014

Journal Articles

Familiar JAK2 G571S Variant Not Linked with Essential Trombocythemia

Irina Panovska-Stavridis, MD PhD, Aleksandar Eftimov, Mr.Sci, Aleksandra Pivkova-Veljanovska, MDPhD, Martin Ivanovski, MD, Lidija Cevreska, MDPhD, Aleksandar J Dimovski, MDPhD

Blood (2014) 124 (21): 5585.

https://doi.org/10.1182/blood.V124.21.5585.5585

Published: 2014

NARROW

Richter Syndrome-Associated Genetic Lesions in TP53 and the Cell Cycle Inhibitors CDKN2A and CDKN2B Induce Transformation of a CD5+ B Cell Subset Characterized By a Restricted IGHV Repertoire, Autoreactivity and BCR Dependence

CXCR4 Loss Reduces the Local Growth of Richter Syndrome Murine and Patient-Derived Xenograft Models and Impairs BCR and VLA-4 Activation

Macrophage- and BCR-derived but not TLR-derived signals support the growth of CLL and Richter syndrome murine models in vivo

Rapid Generation of Murine CLL/Richter Syndrome Models By Multiplexed CRISPR/Cas9 Editing of Common CLL Driver Genes

Prevalence of Allelic Variants and Clonality of IGHV1-69 Expressing B-Cells in Patients with Different Severity of COVID 19 Disease

Chronic Lymphocytic Leukemia Cells with Mutated Nfkbie Are Positively Selected By Microenvironmental Signals and Display Reduced Sensitivity to Ibrutinib Treatment

B-cell receptor signaling and genetic lesions in TP53 and CDKN2A/CDKN2B cooperate in Richter transformation

Correlation of Somatic Mutations and Clinical Characteristics at Presentation in Patients with Essential Thrombocytemia

Familiar JAK2 G571S Variant Not Linked with Essential Trombocythemia

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American Society of Hematology

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American Society of Hematology

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