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Research Article May 13 2025
Transcriptional remodeling shapes therapeutic vulnerability to necroptosis in acute lymphoblastic leukemia
Research Article May 13 2025
Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells
Corynn Kasap,Adila Izgutdina,Bonell Patiño-Escobar,Amrik Singh Kang,Nikhil Chilakapati,Naomi Akagi,Ananya Mishu Manoj,Haley Johnson,Tasfia Rashid,Juwita Werner,Abhilash Barpanda,Huimin Geng,Yu-Hsiu Tony Lin,Sham Rampersaud,Daniel Gil-Alós,Amin Sobh,Daphné Dupéré-Richer,Adolfo Aleman,Gianina Wicaksono,K.M. Kawehi Kelii,Radhika Dalal,Emilio Ramos,Anjanaa Vijayanarayanan,Kiran Lakhani,Fernando Salangsang,Paul Phojanakong,Juan Antonio Camara Serrano,ons Zakraoui,Isa Tariq,Ajai Chari,Alfred Chung,Anupama Deepa Kumar,Thomas Martin,Jeffrey Lee Wolf,Sandy Wong,Veronica Steri,Mala Shanmugam,Lawrence H Boise,Tanja Kortemme,Samir Parekh,Elliot Stieglitz,Jonathan D Licht,William Karlon,Benjamin G Barwick,Arun Wiita
Research Article May 13 2025
A Comprehensive Genetic Study of Classical Hodgkin Lymphoma Using Circulating Tumor DNA
Maria Cristina Pirosa,Alessio Bruscaggin,Lodovico Terzi di Bergamo,Matin Salehi,Federico Jauk,Gabriela Forestieri,Simone Bocchetta,Deborah Piffaretti,Riccardo Moia,Vanessa Cristaldi,Martina di Trani,Georgia Alice Galimberti,Katia Pini,Valeria Spina,Claudia Giordano,Adalgisa Condoluci,Ilaria Romano,Salvatore Annunziata,Fabrizio Bergesio,Renzo Boldorini,Eugenio Borsatti,Pietro Bulian,Eleonora Calabretta,Stephane Chauvie,Francesco Corrado,Stefania Crisci,Marco Cuzzocrea,Rosaria De Filippi,Bernhard Gerber,Michał Kurlapski,Luigi Maria Larocca,Elisabetta Merlo,Andrea Rinaldi,Marcello Rodari,Grzegorz Romanowicz,Gian Mauro Sacchetti,Anastasios Stathis,Georg Stussi,Ilaria Zangrilli,Antonio Pinto,Luca Mazzucchelli,Valter Gattei,Jan Maciej Zaucha,Armando Santoro,Stefan Hohaus,Franco Cavalli,Alexandar Tzankov,Carmelo Carlo-Stella,Gianluca Gaidano,Luca Ceriani, Prof,Emanuele Zucca,Davide Rossi
Research Article May 13 2025
Large B-cell lymphoma imprints a dysfunctional immune phenotype that persists years after treatment
Richard Pelzl,Giulia Benintende,Franziska Gsottberger,Julia Katharina Scholz,Matthias Ruebner,Hao Yao,Kerstin Wendland,Kai Rejeski,Heidi Altmann,Srdjan Petkovic,Lisa Mellenthin,Sabrina Kübel,Moritz Schmiedeberg,Paulina Klein,Agnese Petrera,Rebecca Baur,Sophie Eckstein,Sandra Hoepffner-Grundy,Christoph Röllig,Marion Subklewe,Hanna Huebner,Georg Schett,Andreas Mackensen,Luca Laurenti,Frederik Graw,Simon Völkl,Krystelle Nganou-Makamdop,Fabian Müller
Brief Report May 7 2025
Phase 1/2 Study of High-Dose Palifermin for GVHD Prophylaxis in Patients Undergoing HLA-Matched Unrelated Donor HCT
Research Article May 7 2025
Menin inhibition with revumenib for NPM1-mutated relapsed or refractory acute myeloid leukemia: the AUGMENT-101 study
Martha L. Arellano,Michael J. Thirman,John F. DiPersio,Mael Heiblig,Eytan M. Stein,Andre C. Schuh,Andrius Zucenka,Stéphane De Botton,Carolyn S. Grove,Gabriel N. Mannis,Cristina Papayannidis,Alexander E. Perl,Ghayas C. Issa,Ibrahim Aldoss,Ashish Bajel,David S. Dickens,Michael W.M. Kühn,Ioannis Mantzaris,Emmanuel Raffoux,Elie Traer,irina Amitai,Hartmut Döhner,Corinna Greco,Tibor J. Kovacsovics,Christine M. McMahon,Pau Montesinos,Arnaud Pigneux,Paul J. Shami,Richard M. Stone,Ofir Wolach,John G. Harpel,Yakov Chudnovsky,Li Yu,Rebecca G. Bagley,Angela R. Smith,James S. Blachly
Research Article May 7 2025
Augmented CD47 expression impairs alloreactive T-cell clearance after allo-HCT
Cindy Sheree Flamann,Haroon Shaikh,Carina Matos,Marina Kreutz,Hla Ali,Michael AG Kern,Maike Büttner-Herold,Benedikt Jacobs,Simon Völkl,Christopher Lischer,Christian Kellner,Johannes Berges,Katrin Bitterer,Domenica Saul,Manisha Goel,Cornelia Link-Rachner,Alma Zernecke,Daniela Andrea Weber,Dimitrios Mougiakakos,Andreas Mackensen,Andreas Beilhack,Heiko Bruns
Research Article May 7 2025
BLAST: A Globally Applicable and Molecularly Versatile Survival Model for Chronic Myelomonocytic Leukemia
Ayalew Tefferi,Saubia Fathima,Maymona Abdelmagid,Ali Alsugair,Fnu Aperna,Mahsa Rezasoltani,Muhammad Yousuf,Anuya Natu,Clifford M Csizmar,Mark Gurney,Terra L Lasho,Christy M. Finke,Rashmi Kanagal-Shamanna,Danielle Hammond,Kelly Sharon Chien,Alexandre Bazinet,Courtney D. DiNardo,Tapan M. Kadia,Abhishek A. Mangaonkar,Naval G. Daver,Animesh D Pardanani,Gautam Borthakur,Cinthya J Zepeda-Mendoza,Kaaren K Reichard,Rong He,Sanam Loghavi,Francesco Passamonti,Farhad Ravandi,Koji Sasaki,Dirk Larson,Guillermo Garcia-Manero,Francesco Onida,Naseema Gangat,Guillermo Montalban-Bravo,Mrinal M. Patnaik
Research Article May 7 2025
A multiomic analysis of Waldenström macroglobulinemia defines distinct disease subtypes
Dylan C Gagler,Hussein Ghamlouch,Di Zhang,Patrick Blaney,Avital Tenenbaum,James Blake Langton,Marine Armand,Alexandre Eeckhoutte,Amina Joudat,Michaël Degaud,Michela Esposito,Gaurav Varma,Yubao Wang,Sanghoon Lee,Sanxiong Liu,Oscar B Lahoud,David Kaminetzky,Marc J. Braunstein,Louis Williams,Florence Nguyen-Khac,Brian A Walker,Damien Roos-Weil,Faith E Davies,Olivier A Bernard,Gareth J Morgan
Research Article April 29 2025
The mitochondrial protease ClpP is a metabolic vulnerability and an immunogenic trigger against multiple myeloma.
Tommaso Perini,Paola Zordan,Rossella Del Pizzo,Massimo Resnati,Lisa Viviani,Davide Stefanoni,Laura Cassina,Ugo Paolo Orfanelli,Matteo Trudu,laura oliva,Daniel Lacidogna,Mehmet K. Samur,Maria Materozzi,Denise Drago,Annapaola Andolfo,Marco Patrone,Massimo Degano,Alessandra Boletta,Enrico Milan,Fabio Ciceri,Nikhil C. Munshi,Matteo Bellone,Simone Cenci, MD
Research Article April 25 2025
A phase 2 randomized study of modakafusp alfa as a single agent in patients with relapsed/refractory multiple myeloma
Sarah A Holstein,Shebli Atrash,Hira Mian,Meletios Athanasios Dimopoulos,Fredrik Schjesvold,Rakesh Popat,Nishi Shah,Moshe E Gatt,Christian B. Gocke,Laurent Frenzel,Cyrille Touzeau,Meral Beksac,Salomon Manier,Hila Magen,Patrick Travis,Omar Nadeem,Kaveri Suryanarayan,Cheryl Li,Shuli Li,Allison Nelson,Dasha Cherepanov,Xavier Parot,Dan T Vogl
Research Article April 21 2025
T-ICAHT: Grading and Prognostic Impact of Thrombocytopenia After CAR T-cell Therapy
Kai Rejeski,Jaime Sanz,Teng Fei,Monica S Nair,Hamza Hashmi,Abraham Avigdor,Ofrat Beyar-Katz,Veit L. Bücklein,Kevin J. Curran,Sigrun Einarsdottir,Jonathan H Esensten,Netta Glaubach, Dr,Noa Golan-Accav,Marina Gomez-Llobell,Iris Halamis,Orit Itzhaki,Frederick L. Locke,Sham Mailankody,Ronit Marcus,Marcela V. Maus,M. Lia Palomba,Jae H Park,Marcelo C. Pasquini,Sandeep S Raj,Sridevi Rajeeve,Gilles A. Salles,Michael Scordo,Gunjan L Shah,Avichai Shimoni,Marion Subklewe,Tobias Tix,Saad Z Usmani,Ori Ben Valid,Yannis K. Valtis,Tsila Zuckerman,Nirali N Shah,Miguel-Angel Perales,Roni Shouval
Research Article April 15 2025
Outcomes of PLAT-02 and PLAT-03: Evaluating CD19 CAR T-Cell Therapy and CD19-expressing T-APC Support in Pediatric B-ALL
Brief Report April 10 2025
ZUMA-8: A Phase 1 Study of Brexucabtagene Autoleucel in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia
Research Article April 8 2025
Acalabrutinib-Obinutuzumab Improves Survival vs Chemoimmunotherapy in treatment-naive CLL in the 6-year Follow-up of ELEVATE-TN
Jeff P. Sharman,Miklos Egyed,Wojciech Jurczak,Alan P Skarbnik,Krish Patel,Ian W. Flinn,Manali Kamdar,Talha Munir,Renata Walewska,Marie Hughes,Laura Maria Fogliato,Yair Herishanu,Versha Banerji,George A. Follows,Patricia A Walker,Paolo Ghia,Ann MH Janssens,John C Byrd,Emmanuelle France Ferrant,Alessandra Ferrajoli,William G. Wierda,Catherine Wangui Wachira,Batul T. Suterwala,Paulo A Palhares de Miranda,Veerendra Munugalavadla,Chuan-Chuan Wun,Jennifer A. Woyach
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