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First Edition

Review Article March 25 2025
Metabolic Pathways in Deep Vein Thrombosis: A New Frontier for Therapeutic Intervention
Ivan Budnik,Mariia Kumskova,Anil Chauhan
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Research Article March 24 2025
Daratumumab-Bortezomib-Thalidomide-Dexamethasone for Newly Diagnosed Myeloma: CASSIOPEIA Minimal Residual Disease Results
Jill Corre,Laure Vincent,Philippe Moreau,Benjamin Hebraud,Cyrille Hulin,Marie-Christine Béné,Annemiek Broijl,Denis Caillot,Michel Delforge,Thomas Dejoie,Thierry Facon,Jerome Lambert,Xavier Leleu,Margaret Macro, Dr,Aurore Perrot,Sonja Zweegman,Thomas Filleron,Bastien Cabarrou,Niels W.C.J. van de Donk,Sabrina Mahéo,Winnie Hua,Jianping Wang,Maria Krevvata,Véronique Vanquickelberghe,Carla de Boer,Alba Tuozzo,Fredrik Borgsten,Melissa Rowe,Robin Carson,Soraya Wuilleme,Pieter Sonneveld
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Supplementary data
Research Article March 20 2025
Clonal hematopoiesis is clonally unrelated to multiple myeloma and is associated with specific microenvironmental changes
Marta Lionetti,Margherita Scopetti,Antonio Matera,Akihiro Maeda,Alessio Marella,Francesca Lazzaroni,Giancarlo Castellano,Sonia Fabris,Stefania Pioggia,Silvia Lonati,Alfredo Marchetti,Alessandra Cattaneo,Marta Tornese,Antonino Neri, Dr,Claudia Leoni,Loredana Pettine,Valentina Traini,Ilaria Silvestris,Marzia Barbieri,Giuseppina Fabbiano,Domenica Ronchetti,Elisa Taiana,Claudio De Magistris,Matteo Claudio Da Via',Francesco Passamonti,Niccolò Bolli
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Supplementary data
Research Article March 19 2025
NKG2D-mediated cytotoxicity of CD4 cytotoxic T cells in multiple myeloma
Sojeong Kim,Jeong-Eun Kwak,June-Young Koh,Ji Eun Lee,Hye Won Kook,Minchae Kim,Haerim Chung,Yuri Kim,Soo Jeong Kim,Jin Seok Kim,June-Won Cheong,Min Goo Lee,Hoyoung Lee,Su-Hyung Park,Eui-Cheol Shin,Saeam Shin,Sun Och Yoon,Il-Kyu Choi,Jeong Seok Lee,Hyunsoo Cho
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Supplementary data
Brief Report March 16 2025
The neutrophil antigen 3a/b polymorphism in SLC44A2 unexpectedly encodes Csa/Csb red cell antigens
Romain Duval,Alissa Soudry,Jonathan De Oliveira Rios,Sarah Liane Linguet,Miguel Taillepierre,Graziella Matesic,Alexandre Raneri,Guy Laiguillon,Emilie Le Toriellec,Emilie-Fleur Gautier,Damien Vainqueur,Jérôme Babinet,Cécile Masson,jean Christophe Gelly,Caroline Le Van Kim,Marc Romana,Dawei Chen,Sentot Santoso,Berengere Koehl,Thierry Peyrard,Slim Azouzi
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Supplementary data
Discussion March 16 2025
Proteostasis Disruption in Inherited Bone Marrow Failure Syndromes
Helena Yu,Robert Signer
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Discussion March 16 2025
Pathogenesis of Paroxysmal Nocturnal Hemoglobinuria
Lucio Luzzatto,Shinji Nakao
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Review Article March 16 2025
Biology as vulnerability in follicular lymphoma: genetics, epigenetics, and immunogenetics
Ferran Araujo-Ayala,Wendy Béguelin
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Research Article March 16 2025
Itacitinib for the Prevention of IEC Therapy-Associated CRS: Results From the Two-Part Phase 2 INCB 39110-211 Study
Matthew J. Frigault,Richard T. Maziarz,Jae H Park,Aleksandr Lazaryan,Nirav N Shah,Jakub Svoboda,Lazaros J. Lekakis,Ran Reshef,Christine L. Phillips,Lea Burke,Jing Lei,Michael Pratta,Rodica Morariu-Zamfir,John F. DiPersio
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Research Article March 16 2025
Ruxolitinib combined with dexamethasone for adult patients with newly diagnosed hemophagocytic lymphohistiocytosis in China
De Zhou,Xianbo Huang,Lixia Zhu,Xuelian Hu,Xiudi Yang,Mixue Xie,Xin Huang,Fang Yu,Juying Wei,Liya Ma,Jingjing Zhu,Shuqi Zhao,Wanzhuo Xie,Hongyan Tong,Jie Jin,Xiujin Ye
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Research Article March 16 2025
Loss of BCL7A Permits IRF4 Transcriptional Activity and Cellular Growth in Multiple Myeloma
Chandraditya Chakraborty,Srikanth Talluri,Moritz Binder,Eugenio Morelli,Jessica Encinas Mayoral,Sanika Derebail,Anil Aktas Samur,Charles B. Epstein,Kenneth C. Anderson,Masood A Shammas,Mehmet K. Samur,Mariateresa Fulciniti,Nikhil C. Munshi
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Research Article March 16 2025
Genetic and epigenetic mechanisms of GPRC5D loss after anti-GPRC5D CAR T-cell therapy in multiple myeloma
Sha Ma,Jieyun Xia,Miao Zhang,Wenyu Li,Meng Xiao,Yuqian Sha,Wenya Wang,Jianteng Zhou,Ying Wang,Kunming Qi,Chunling Fu,Zengtian Sun,Dian Zhou,Qian Sun,Tingting Qiu,Zhiling Yan,Feng Zhu,Wei Chen,Hai Cheng,Wei Sang,Jiang Cao,Depeng Li,Zhenyu Zhen Li,Mariateresa Fulciniti,Yao Yao,Kailin Xu,Mingshan Niu
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Research Article March 16 2025
Blunted CD40-responsive enhancer activation in CREBBP-mutant lymphomas can be restored by enforced CD4 T-cell engagement
Haopeng Yang,Wenchao Zhang,Vida Ravanmehr,Guiling Cui,Kevin Bowman,Ruidong Chen,Jared Henderson,Shyanne Ruby Lockman,Estela Rojas,Ashley Lauren Wilson,Sydney Parsons,Ariel Mechaly,Leslie Regad,Ahmed Haouz,Christopher R. Flowers,Sattva S. Neelapu,Loretta J. Nastoupil,Richard Eric Davis,Qing Deng,Fernando Rodrigues Lima,Michael R Green
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Research Article March 12 2025
Large-scale dependency and drug screens characterize the therapeutic vulnerabilities of Multiple Myeloma with 1q+
Romanos Sklavenitis-Pistofidis,Elizabeth D Lightbody,Mairead Reidy,Junko Tsuji,Jean-Baptiste Alberge,Michelle P Aranha,Daniel Lewis Heilpern-Mallory,Harvey G. Roweth,Daisy Huyng,Stephen Jun Fei Chong,Anna Y. Chung,Jeremy Zhang,Liam Hackett,Nicholas J Haradhvala,Ting Wu,Nang Kham Su,Brianna Berrios,Saveliy Belkin,Ankit K. Dutta,Ryan A Knudson,Carolyn Brandt,Patricia T. Greipp,Matthew S. Davids,Maria Papaioannou,Gad Getz,Irene M Ghobrial,Salomon Manier
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Research Article March 12 2025
Efficacy of Combined CD38 and PD1 Inhibition with Isatuximab and Cemiplimab for Relapsed/Refractory NK/T-Cell Lymphoma
Seok Jin Kim,Jing Quan Lim,Sang Eun Yoon,Deok-Hwan Yang,Ji Hyun Lee,Sung Yong Oh,Yoon Seok Choi,Seong Hyun Jeong,Min Kyoung Kim,Sung-Nam Lim,Junhun Cho,Bon Park,Kyung Ju Ryu,Seunghyun Choi,Yoon Park,Kerry May Huifen Lim,Nur Ayuni Binte Muhammad Taib,Choon Kiat Ong,Soon Thye Lim,Won Seog Kim
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Research Article March 12 2025
A Controlled Trial for Preventing Priapism in Sickle Cell Anemia: Hydroxyurea plus Placebo vs Hydroxyurea plus Tadalafil
Ibrahim Musa Idris,Aminu Abba Yusuf,Ismail Isah Ismail,Awwal Musa Borodo,Mustapha Shuaibu Hikima,Shehu Abubakar Kana,Tukur Aliyu,Kabiru Musan Gedu,Atiku Usman Jibrillah, MBBS, FWACS,Sani Ali Aji,Aisha Kuliya-Gwarzo,Kabeer Bello Mohammed,Jamil A . Galadanci,Rukayya Sunusi Alkassim,Mohammad Abba Suwaid,Nafiu Hussaini,Mark Rodeghier,Arthur Louis Burnett, II,Michael R DeBaun
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Review Article February 28 2025
Exploring the thrombus niche: Lessons learned and potential therapeutic opportunities
John W. Weisel,Rustem I Litvinov
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Review Article February 28 2025
The Future of Follicular Lymphoma Management: Strategies on the Horizon
Erin Mulvey,Sarah C. Rutherford,John P. Leonard
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Review Article February 28 2025
End points and Outcomes in Follicular Lymphoma: What should we measure, how, and why?
Mengyang Di,Matthew J. Maurer,Christopher R. Flowers
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Research Article February 26 2025
Aberrant single-cell phenotype and clinical implications of genotypically defined polyclonal plasma cells in myeloma
Matteo Claudio Da Viá,Francesca Lazzaroni,Antonio Matera,Alessio Marella,Akihiro Maeda,Claudio De Magistris,Loredana Pettine,Antonio Giovanni Solimando,Vanessa Desantis,Giuseppe M Peretti,Laura Mangiavini,Riccardo Giorgino,Sonia Fabris,Stefania Pioggia,Alfredo Marchetti,Marzia Barbieri,Silvia Lonati,Alessandra Cattaneo,Marta Tornese,Margherita Scopetti,Emanuele Calvi,Nayyer Latifinavid,Giancarlo Castellano,Federica Torricelli, Dr,Antonino Neri,Cathelijne Fokkema,Tom Cupedo,Marta Lionetti,Francesco Passamonti,Niccolò Bolli
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Research Article February 26 2025
Magrolimab plus azacitidine vs physician's choice for untreated TP53-mutated acute myeloid leukemia: the ENHANCE-2 study
Joshua F. Zeidner,David A. Sallman,Christian Récher,Naval G. Daver,Anskar YH Leung,Devendra K. Hiwase,Marion Subklewe,Thomas Pabst,Pau Montesinos,Richard A Larson,Lindsay Wilde,Anoop K. Enjeti,Ichiro Kawashima,Cristina Papayannidis,Jenny O'Nions,Lisa Johnson,Mei Dong,Julie Huang,Taravat Bagheri,Gal Hacohen-Kleiman,Calvin Lee,Paresh Vyas
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Review Article January 27 2025
Platelet activation and signaling in thrombus formation
Frauke Swieringa,Johan W.M. Heemskerk,Alice Assinger
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Review Article January 27 2025
Factor XIII: Driving (Cross-)Links in Hemostasis, Thrombosis, and Disease
James P Luyendyk,Matthew J. Flick,Alisa S. Wolberg
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Review Article January 27 2025
Frontline treatment of follicular lymphoma: What will it take to change current practice?
Emmanuel Bachy,Kim Linton
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Research Article January 22 2025
Isatuximab, Carfilzomib, Lenalidomide, and Dexamethasone Induction in Newly Diagnosed Myeloma: Analysis of the MIDAS Trial
Aurore Perrot,Cyrille Touzeau,Jerome Lambert,Cyrille Hulin,Denis Caillot,Lionel Karlin,Bertrand Arnulf,Philippe Rey,Laurent Garderet,Margaret Macro, Dr,Martine Escoffre-Barbe,Julie Gay,Thomas Chalopin,Romain Gounot,Jean Marc Schiano de Colella,Mourad Tiab,Mohamad Mohty,Frédérique Kuhnowski,Jean Fontan,Salomon Manier,Frederique Orsini Piocelle,Laure Vincent,Sophie Rigaudeau,Xavier Leleu,Benjamin Hébraud,Laurent Flet,Jean-Valère Malfuson,Caroline Jacquet,Driss Chaoui,Nathalie Meuleman,Wajed Abarah,Lydia Montes,Riad Benramdane,Cécile Sonntag,Hacene Zerazhi,Alina Danu,Olivier Allangba,Mamoun Dib,Murielle Roussel,Sophie Cereja,Julien Depaus,Nicolas Branche,Hélène Demarquette,Valentine Richez,Cherel Bruiec,Laurent Frenzel,Marie-Christiane MB Vekemans,Noemie Bigot,Hervé Avet-Loiseau,Jill Corre,Philippe Moreau
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