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Journal Articles

Pentostatin Low-Dose TBI Is an Effective Conditioning Regimen That Permits Donor Engraftment in Patients with High Co-Morbidities Undergoing the First Transplant or Prior to a Second Transplant

Ani Gvajaia, Joseph Rimando, William Blum, Colin A. Vale, Cynthia R. Giver, Elaina L. Corbett, Kevin Hall, Kristina Murphy, Mary Jo Lechowicz, Michel Conn, Minal Surati, Muna Qayed, Amelia Langston, Edmund K. Waller

Blood (2024) 144 (Supplement 1): 7325.

https://doi.org/10.1182/blood-2024-211880

Published: 2024

Journal Articles

Preliminary Safety and Efficacy of Myeloablative Orca-Q with No GvHD Prophylaxis for Treatment of Advanced Hematologic Malignancies

Mehrdad Abedi, Samer A. Srour, Amandeep Salhotra, Rasmus T. Hoeg, Edmund K. Waller, Hannah Choe, Anna Pavlova, Tamara Zharkevich, J. Scott McClellan, Nathaniel B. Fernhoff, Everett H. Meyer, Robert Lowsky

Blood (2024) 144 (Supplement 1): 382.

https://doi.org/10.1182/blood-2024-204256

Published: 2024

Journal Articles

Intermediate Dose Post-Transplant Cyclophosphamide Is Associated with Faster Engraftment and Similar Other Outcomes When Compared with Full Dose Post-Transplant Cyclophosphamide Among Patients Undergoing Allogeneic Transplantation: A Single Center Retrospective Analysis

Joseph Rimando, Michel Conn, William Blum, Jason T Romancik, Colin Vale, Amelia Langston, Edmund K. Waller, Kevin Hall

Blood (2024) 144 (Supplement 1): 3521.

https://doi.org/10.1182/blood-2024-198921

Published: 2024

Journal Articles

Development of Humanized Antibodies Against Vasoactive Intestinal Polypeptide for Increased T Cell Anti-Leukemia Activity

Justin Adeyeye, Cynthia R. Giver, Jamie Cohen, Yuou Wang, Tysheena P. Charles, Khue G. Nguyen, Jian-Ming Li, Jens Wrammert, David A. Zaharoff, Edmund K. Waller

Blood (2024) 144 (Supplement 1): 4964.

https://doi.org/10.1182/blood-2024-203518

Published: 2024

Journal Articles

Observational Comparison of Overall Survival between Phase 1b Orca-T and Registry-Based Post-Transplant Cyclophosphamide Patients

Blood (2024) 144 (Supplement 1): 694.

https://doi.org/10.1182/blood-2024-205917

Published: 2024

Journal Articles

Modulating the Vasoactive Intestinal Peptide (VIP) Pathway Reprograms Superior CAR T Cells

Blood (2024) 144 (Supplement 1): 7154.

https://doi.org/10.1182/blood-2024-208090

Published: 2024

Journal Articles

Uncovering the Tumor Antigen Landscape in Patients Undergoing Dendritic Cell/Myeloma Fusion Vaccine with Lenalidomide Maintenance Treatment

Blood (2024) 144 (Supplement 1): 3289.

https://doi.org/10.1182/blood-2024-211352

Published: 2024

Journal Articles

The Dominant Effect of the Gut Microbiome on GvHD in Mouse Models of Allo-BMT

Shayna Jankowski, Shuhua Wang, Yiwen Helen Li, Cynthia R. Giver, Edmund K. Waller

Blood (2024) 144 (Supplement 1): 4914.

https://doi.org/10.1182/blood-2024-212102

Published: 2024

Journal Articles

VIP Expression Drives an Immunosuppressive Tumor Microenvironment in TP53-Mutated AML

Fanyuan Zeng, Kiranj Chaudagar, Yuou Wang, Jian-Ming Li, Edmund K. Waller

Blood (2024) 144 (Supplement 1): 4299.

https://doi.org/10.1182/blood-2024-208170

Published: 2024

Journal Articles

Early B-cell development and B-cell maturation are impaired in patients with active hemophagocytic lymphohistiocytosis

Jenny Shim, Sunita Park, Suresh Venkateswaran, Deepak Kumar, Chengyu Prince, Vaunita Parihar, Larkin Maples, Edmund K. Waller, Subra Kugathasan, Michael Briones, Miyoung Lee, Curtis J. Henry, Sampath Prahalad, Shanmuganathan Chandrakasan

Blood (2023) 142 (23): 1972–1984.

https://doi.org/10.1182/blood.2023020426

Published: 2023

Includes: Supplemental data

Journal Articles

Vasoactive Intestinal Peptide Signaling in Transplant Recipients Modulates Gut Microbiome Diversity and Regulates Graft-Versus-Host Disease

Yiwen Helen Li, Shuhua Wang, Edmund K. Waller

Blood (2023) 142 (Supplement 1): 2046.

https://doi.org/10.1182/blood-2023-190787

Published: 2023

Journal Articles

Optimizing Outcomes with Myeloablative Conditioning in Older Patients: Efficacy and Safety of Precision Engineered Orca-T in Patients > 55 Years Old with Hematologic Malignancies

Caspian H. Oliai, Jeremy M. Pantin, Rasmus T. Hoeg, Lori S. Muffly, Sagar S. Patel, Arpita Gandhi, Robert Lowsky, Amandeep Salhotra, Bhagirathbhai Dholaria, Edmund K. Waller, Samer A. Srour, Anna Pavlova, Nathaniel B. Fernhoff, Irene Agodoa, J. Scott McClellan, Mehrdad Abedi, Robert S. Negrin, Everett H. Meyer

Blood (2023) 142 (Supplement 1): 230.

https://doi.org/10.1182/blood-2023-186749

Published: 2023

Journal Articles

High Disease-Free Survival in Patients with High-Risk MDS Treated with Orca-T

Arpita Gandhi, Rasmus T. Hoeg, Sagar S. Patel, Edmund K. Waller, Jeremy M. Pantin, Caspian H. Oliai, J. Scott McClellan, Anna Pavlova, Irene Agodoa, Nathaniel B. Fernhoff, Everett H. Meyer

Blood (2023) 142 (Supplement 1): 2230.

https://doi.org/10.1182/blood-2023-188994

Published: 2023

Journal Articles

Intermittent Sargramostim Administration Expands Proliferating Naïve T Cells, Tregs, HLA-DR+ PD-L1+ Monocytes and Myeloid-Derived Suppressor Cells: Results from a Randomized Placebo-Controlled Clinical Trial of GM-CSF in Patients with Peripheral Artery Disease

Alireza Rahbar, Mohammad S. Hossain, Cynthia R. Giver, Shivang Desai, Yazan Haroun, Tanveer Kauser, Kiran Ejaz, Arshed A. Quyyumi, Edmund K. Waller

Blood (2023) 142 (Supplement 1): 5355.

https://doi.org/10.1182/blood-2023-186848

Published: 2023

Journal Articles

Donor T Cell Infusions Limit Novel Immune Checkpoint Therapy in Pancreatic Cancer: Implications for Adoptive T Cell Therapy

Po-Chih Hsu, Edmund K. Waller, Tenzin Passang, Shuhua Wang, Jian-Ming Li

Blood (2023) 142 (Supplement 1): 2144.

https://doi.org/10.1182/blood-2023-190645

Published: 2023

Journal Articles

Safety and Efficacy of Orca-Q with Haploidentical Donors for the Treatment of Advanced Hematologic Malignancies without the Use of Post-Transplant Cyclophosphamide

Samer A. Srour, Amandeep Salhotra, Robert Lowsky, Rasmus T. Hoeg, Edmund K. Waller, Anna Pavlova, J. Scott McClellan, Nathaniel B. Fernhoff, Everett H. Meyer, Mehrdad Abedi

Blood (2023) 142 (Supplement 1): 773.

https://doi.org/10.1182/blood-2023-189534

Published: 2023

Journal Articles

Long Term Durable Responses in Relapsed/Refractory (r/r) ALL, DLBCL, and FL Patients Treated with Tisagenlecleucel and Its Association with Persistence of CAR T-Cells

Rakesh Awasthi, Edward Waldron, Stephan Grupp, Michael A. Pulsipher, Peter Bader, Stephen J Schuster, Richard T Maziarz, Edmund K. Waller, Ulrich Jaeger, Catherine Thieblemont, Martin Dreyling, Nathan Fowler, Harald Jakob Maier, Jennifer Willert

Blood (2023) 142 (Supplement 1): 4872.

https://doi.org/10.1182/blood-2023-181663

Published: 2023

Journal Articles

Antagonizing Vasoactive Intestinal Peptide (VIP) Receptors on CAR T Cells Improves Efficacy and Persistence

Heather Lin, Dejah Blake, Abhijay Mudigonda, Alysa N Evans, Ruby Freeman, Tanisha Sinha, Fan Fei, Elyse Christensen, Tenzin Passang Fnu, Sruthi Ravindranathan, Tongrui Liu, Lily Yang, Edmund K. Waller, Sarwish Rafiq

Blood (2023) 142 (Supplement 1): 4806.

https://doi.org/10.1182/blood-2023-182952

Published: 2023

Journal Articles

Early Plasma Levels of IL7 and IL15 Predict Response to Chimeric Antigen Receptor T Cell Therapy (CAR-T) in Large B-Cell Lymphoma (LBCL) Patients

Fanyuan Zeng, Hanwen Zhang, Shuhua Wang, Tenzin Passang, Yiwen Helen Li, Christopher Ronald Funk, Sarah Wyman, Colin B O'Leary, Aseala I Abousaud, Yuan Liu, Kavita Dhodapkar, Edmund K. Waller, Jean L. Koff

Blood (2023) 142 (Supplement 1): 6112.

https://doi.org/10.1182/blood-2023-189248

Published: 2023

Journal Articles

Post-Hoc Analysis of Measurable Residual Disease from BMT-CTN 1506/Morpho: FLT3-ITD Variant Allele Frequency and Survival Are Highly Correlated

Blood (2023) 142 (Supplement 1): 973.

https://doi.org/10.1182/blood-2023-177929

Published: 2023

NARROW

Pentostatin Low-Dose TBI Is an Effective Conditioning Regimen That Permits Donor Engraftment in Patients with High Co-Morbidities Undergoing the First Transplant or Prior to a Second Transplant

Preliminary Safety and Efficacy of Myeloablative Orca-Q with No GvHD Prophylaxis for Treatment of Advanced Hematologic Malignancies

Intermediate Dose Post-Transplant Cyclophosphamide Is Associated with Faster Engraftment and Similar Other Outcomes When Compared with Full Dose Post-Transplant Cyclophosphamide Among Patients Undergoing Allogeneic Transplantation: A Single Center Retrospective Analysis

Development of Humanized Antibodies Against Vasoactive Intestinal Polypeptide for Increased T Cell Anti-Leukemia Activity

Observational Comparison of Overall Survival between Phase 1b Orca-T and Registry-Based Post-Transplant Cyclophosphamide Patients

Modulating the Vasoactive Intestinal Peptide (VIP) Pathway Reprograms Superior CAR T Cells

Uncovering the Tumor Antigen Landscape in Patients Undergoing Dendritic Cell/Myeloma Fusion Vaccine with Lenalidomide Maintenance Treatment

The Dominant Effect of the Gut Microbiome on GvHD in Mouse Models of Allo-BMT

VIP Expression Drives an Immunosuppressive Tumor Microenvironment in TP53-Mutated AML

Early B-cell development and B-cell maturation are impaired in patients with active hemophagocytic lymphohistiocytosis

Vasoactive Intestinal Peptide Signaling in Transplant Recipients Modulates Gut Microbiome Diversity and Regulates Graft-Versus-Host Disease

Optimizing Outcomes with Myeloablative Conditioning in Older Patients: Efficacy and Safety of Precision Engineered Orca-T in Patients > 55 Years Old with Hematologic Malignancies

High Disease-Free Survival in Patients with High-Risk MDS Treated with Orca-T

Intermittent Sargramostim Administration Expands Proliferating Naïve T Cells, Tregs, HLA-DR+ PD-L1+ Monocytes and Myeloid-Derived Suppressor Cells: Results from a Randomized Placebo-Controlled Clinical Trial of GM-CSF in Patients with Peripheral Artery Disease

Donor T Cell Infusions Limit Novel Immune Checkpoint Therapy in Pancreatic Cancer: Implications for Adoptive T Cell Therapy

Safety and Efficacy of Orca-Q with Haploidentical Donors for the Treatment of Advanced Hematologic Malignancies without the Use of Post-Transplant Cyclophosphamide

Long Term Durable Responses in Relapsed/Refractory (r/r) ALL, DLBCL, and FL Patients Treated with Tisagenlecleucel and Its Association with Persistence of CAR T-Cells

Antagonizing Vasoactive Intestinal Peptide (VIP) Receptors on CAR T Cells Improves Efficacy and Persistence

Early Plasma Levels of IL7 and IL15 Predict Response to Chimeric Antigen Receptor T Cell Therapy (CAR-T) in Large B-Cell Lymphoma (LBCL) Patients

Post-Hoc Analysis of Measurable Residual Disease from BMT-CTN 1506/Morpho: FLT3-ITD Variant Allele Frequency and Survival Are Highly Correlated

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American Society of Hematology

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American Society of Hematology

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