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J. Scott McClellan
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Journal Articles

Preliminary Safety and Efficacy of Myeloablative Orca-Q with No GvHD Prophylaxis for Treatment of Advanced Hematologic Malignancies

Mehrdad Abedi, Samer A. Srour, Amandeep Salhotra, Rasmus T. Hoeg, Edmund K. Waller, Hannah Choe, Anna Pavlova, Tamara Zharkevich, J. Scott McClellan, Nathaniel B. Fernhoff, Everett H. Meyer, Robert Lowsky
Journal: Blood
Blood (2024) 144 (Supplement 1): 382.
https://doi.org/10.1182/blood-2024-204256
Published: 2024
Journal Articles

Observational Comparison of Overall Survival between Phase 1b Orca-T and Registry-Based Post-Transplant Cyclophosphamide Patients

Caspian H. Oliai, Rasmus T. Hoeg, Arpita Gandhi, Lori Muffly, Samer A. Srour, Rohtesh S. Mehta, Edmund K. Waller, Robert Lowsky, Sagar S. Patel, Bhagirathbhai Dholaria, Jeremy Pantin, Amandeep Salhotra, Joseph P. McGuirk, Steven M. Devine, Alexandra Gomez-Arteaga, Rawan Faramand, Roni Tamari, Jennifer Holter-Chakrabarty, Betty K. Hamilton, Antonio M. Jimenez Jimenez, Anna Pavlova, Nathaniel B. Fernhoff, J. Scott McClellan, Mehrdad Abedi, Robert S. Negrin, Everett H. Meyer
Journal: Blood
Blood (2024) 144 (Supplement 1): 694.
https://doi.org/10.1182/blood-2024-205917
Published: 2024
Journal Articles

Safety and Efficacy of Orca-Q with Haploidentical Donors for the Treatment of Advanced Hematologic Malignancies without the Use of Post-Transplant Cyclophosphamide

Samer A. Srour, Amandeep Salhotra, Robert Lowsky, Rasmus T. Hoeg, Edmund K. Waller, Anna Pavlova, J. Scott McClellan, Nathaniel B. Fernhoff, Everett H. Meyer, Mehrdad Abedi
Journal: Blood
Blood (2023) 142 (Supplement 1): 773.
https://doi.org/10.1182/blood-2023-189534
Published: 2023
Journal Articles

High Disease-Free Survival in Patients with High-Risk MDS Treated with Orca-T

Arpita Gandhi, Rasmus T. Hoeg, Sagar S. Patel, Edmund K. Waller, Jeremy M. Pantin, Caspian H. Oliai, J. Scott McClellan, Anna Pavlova, Irene Agodoa, Nathaniel B. Fernhoff, Everett H. Meyer
Journal: Blood
Blood (2023) 142 (Supplement 1): 2230.
https://doi.org/10.1182/blood-2023-188994
Published: 2023
Journal Articles

Optimizing Outcomes with Myeloablative Conditioning in Older Patients: Efficacy and Safety of Precision Engineered Orca-T in Patients > 55 Years Old with Hematologic Malignancies

Caspian H. Oliai, Jeremy M. Pantin, Rasmus T. Hoeg, Lori S. Muffly, Sagar S. Patel, Arpita Gandhi, Robert Lowsky, Amandeep Salhotra, Bhagirathbhai Dholaria, Edmund K. Waller, Samer A. Srour, Anna Pavlova, Nathaniel B. Fernhoff, Irene Agodoa, J. Scott McClellan, Mehrdad Abedi, Robert S. Negrin, Everett H. Meyer
Journal: Blood
Blood (2023) 142 (Supplement 1): 230.
https://doi.org/10.1182/blood-2023-186749
Published: 2023
Journal Articles

Orca-Q Demonstrates Favorable GvHD-and-Relapse-Free Survival in Haploidentical Transplants without Post-Transplant Cyclophosphamide

Amandeep Salhotra, Samer A Srour, Rasmus T Hoeg, Ayman Saad, Everett H Meyer, Anna Pavlova, Edmund K. Waller, Mwe Mwe Chao, J Scott McClellan, Nathaniel B Fernhoff, Robert Lowsky, Mehrdad Abedi
Journal: Blood
Blood (2022) 140 (Supplement 1): 1865–1866.
https://doi.org/10.1182/blood-2022-170459
Published: 2022
Journal Articles

Rapid Immune Reconstitution and Elevated Regulatory T Cell Frequencies in Patients Treated with Orca-T

Everett H Meyer, M Scott Killian, Anna Pavlova, Cameron Bader, Sean Summers, Fernando Teque, J Scott McClellan, Nathaniel B Fernhoff
Journal: Blood
Blood (2022) 140 (Supplement 1): 7656–7657.
https://doi.org/10.1182/blood-2022-164468
Published: 2022
Journal Articles

Precision-Engineered Cell Therapy Orca-T Demonstrates High Relapse-Free Survival at 1 Year While Reducing Graft-Versus-Host Disease and Toxicity

Caspian Oliai, Rasmus T Hoeg, Anna Pavlova, Arpita Gandhi, Lori Muffly, Rohtesh S. Mehta, Samer A Srour, Edmund K. Waller, Robert Lowsky, Sagar S. Patel, Bhagirathbhai Dholaria, Carlos Bachier, Jeremy M. Pantin, Amandeep Salhotra, Joseph P. McGuirk, Nathaniel B Fernhoff, J Scott McClellan, Mehrdad Abedi, Robert S. Negrin, Everett H Meyer
Journal: Blood
Blood (2022) 140 (Supplement 1): 654–656.
https://doi.org/10.1182/blood-2022-165654
Published: 2022
Journal Articles

Outcomes for Myelofibrosis Patients Following Myeloablative Allogeneic Stem Cell Transplantation Using the Orca-T Graft from HLA-Matched Related and Unrelated Donors

Arpita Gandhi, Anna Moroz, Lori Muffly, Parveen Shiraz, Levanto Schachter, Nathaniel B Fernhoff, J Scott McClellan, Robert S. Negrin, Jason Gotlib, Everett H Meyer
Journal: Blood
Blood (2021) 138 (Supplement 1): 1819.
https://doi.org/10.1182/blood-2021-150521
Published: 2021
Journal Articles

Orca-T Results in High Gvhd-Free and Relapse-Free Survival Following Myeloablative Conditioning for Hematological Malignancies: Results of a Single Center Phase 2 and a Multicenter Phase 1b Study

Rasmus T. Hoeg, Anna Moroz, Arpita Gandhi, Lori Muffly, Parveen Shiraz, Caspian Oliai, Rohtesh S. Mehta, Samer A. Srour, Joseph P. McGuirk, Edmund K. Waller, Sally Arai, Laura J. Johnston, Robert Lowsky, Andrew R. Rezvani, Wen-Kai Weng, David B. Miklos, Matthew J. Frank, John Tamaresis, Ying Lu, Vaibhav Agrawal, Nathaniel B Fernhoff, Gerhard Bauer, Amy Putnam, J Scott McClellan, Bronwen E. Shaw, Mehrdad Abedi, Robert S. Negrin, Everett H Meyer
Journal: Blood
Blood (2021) 138 (Supplement 1): 98.
https://doi.org/10.1182/blood-2021-154191
Published: 2021