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Volume 96, Issue 3

August 1 2000

In this Issue

PLENARY PAPERS
ERRATA
REVIEW ARTICLES
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
RED CELLS
TRANSFUSION MEDICINE
TRANSPLANTATION
BRIEF REPORTS
CORRESPONDENCE
10
17

PLENARY PAPERS

Prolonged survival and tissue trafficking following adoptive transfer of CD4ζ gene-modified autologous CD4⁺ and CD8⁺ T cells in human immunodeficiency virus–infected subjects

Ronald T. Mitsuyasu,Peter A. Anton,Steven G. Deeks,David T. Scadden,Elizabeth Connick,Matthew T. Downs,Andreas Bakker,Margo R. Roberts,Carl H. June,Sayeh Jalali,Andy A. Lin,Rukmini Pennathur-Das,Kristen M. Hege

View Articletitled, Prolonged survival and tissue trafficking following adoptive transfer of CD4ζ gene-modified autologous CD4+ and CD8+ T cells in human immunodeficiency virus–infected subjects

Molecular characterization of a granulocyte macrophage–colony-stimulating factor receptor α subunit-associated protein, GRAP

Jiangling Tu,Nicos Karasavvas,Mark L. Heaney,Juan Carlos Vera,David W. Golde

View Articletitled, Molecular characterization of a granulocyte macrophage–colony-stimulating factor receptor α subunit-associated protein, GRAP

α-Thalassemia resulting from a negative chromosomal position effect

Virginia M. Barbour,Cristina Tufarelli,Jacqueline A. Sharpe,Zoe E. Smith,Helena Ayyub,Cynthia A. Heinlein,Jacqueline Sloane-Stanley,Karel Indrak,William G. Wood,Douglas R. Higgs

View Articletitled, α-Thalassemia resulting from a negative chromosomal position effect

ERRATA

Erratum in Brugger et al. Positively selected autologous blood CD34+ cells and unseparated peripheral blood progenitor cells mediate identical hematopoietic engraftment after high-dose VP16, ifosfamide, carboplatin, and epirubicin. Blood. 1994;84:1421-1426.

View Articletitled, Erratum in Brugger et al. Positively selected autologous blood CD34+ cells and unseparated peripheral blood progenitor cells mediate identical hematopoietic engraftment after high-dose VP16, ifosfamide, carboplatin, and epirubicin. Blood. 1994;84:1421-1426.

Erratum in Bang et al. Unique processing pathways within recipient antigen-presenting cells determine IgG immunity against donor platelet MCH antigens. Blood. 2000;95:1735-1742.

View Articletitled, Erratum in Bang et al. Unique processing pathways within recipient antigen-presenting cells determine IgG immunity against donor platelet MCH antigens. Blood. 2000;95:1735-1742.

Erratum in Alcobia et al. Spatial associations of centromeres in the nuclei of hematopoietic cells: evidence for cell-type-specific organizational patterns. Blood. 2000;95:1608-1615.

View Articletitled, Erratum in Alcobia et al. Spatial associations of centromeres in the nuclei of hematopoietic cells: evidence for cell-type-specific organizational patterns. Blood. 2000;95:1608-1615.

REVIEW ARTICLES

The role of immunoglobulin translocations in the pathogenesis of B-cell malignancies

Tony G. Willis,Martin J. S. Dyer

View Articletitled, The role of immunoglobulin translocations in the pathogenesis of B-cell malignancies

Erythropoietin, iron, and erythropoiesis

Lawrence T. Goodnough,Barry Skikne,Carlo Brugnara

View Articletitled, Erythropoietin, iron, and erythropoiesis

CHEMOKINES

Induction of monocyte– and T-cell–attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation

Angela Panoskaltsis-Mortari,Robert M. Strieter,John R. Hermanson,Konstantin V. Fegeding,William J. Murphy,Catherine L. Farrell,David L. Lacey,Bruce R. Blazar

View Articletitled, Induction of monocyte– and T-cell–attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation

LEC induces chemotaxis and adhesion by interacting with CCR1 and CCR8

O. M. Zack Howard,Hui Fang Dong,Aiko-Konno Shirakawa,Joost J. Oppenheim

View Articletitled, LEC induces chemotaxis and adhesion by interacting with CCR1 and CCR8

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Heparin-induced thrombocytopenia with thromboembolic complications: meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range
Clinical Trials & Observations

Andreas Greinacher,Petra Eichler,Norbert Lubenow,Harald Kwasny,Matthias Luz

View Articletitled, Heparin-induced thrombocytopenia with thromboembolic complications: meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range

Prognostic factors in Waldenström macroglobulinemia: a report on 232 patients with the description of a new scoring system and its validation on 253 other patients
Clinical Trials & Observations

Pierre Morel,Mathieu Monconduit,Dominique Jacomy,Pascal Lenain,Bernard Grosbois,Christine Bateli,Thierry Facon,Isabelle Dervite,Francis Bauters,Albert Najman,Aimery de Gramont,Eric Wattel

View Articletitled, Prognostic factors in Waldenström macroglobulinemia: a report on 232 patients with the description of a new scoring system and its validation on 253 other patients

Constitutive elevation of serum alpha-fetoprotein in Fanconi anemia
Clinical Trials & Observations

Bruno Cassinat,Philippe Guardiola,Sylvie Chevret,Marie-Hélène Schlageter,Marie-Elisabeth Toubert,Jean-Didier Rain,Eliane Gluckman

View Articletitled, Constitutive elevation of serum alpha-fetoprotein in Fanconi anemia

Successful in vivo purging of CD34-containing peripheral blood harvests in mantle cell and indolent lymphoma: evidence for a role of both chemotherapy and rituximab infusion
Clinical Trials & Observations

Michele Magni,Massimo Di Nicola,Liliana Devizzi,Paola Matteucci,Fabrizio Lombardi,Lorenza Gandola,Fernando Ravagnani,Roberto Giardini,Giuseppe Dastoli,Corrado Tarella,Alessandro Pileri,Gianni Bonadonna,Alessandro M. Gianni

View Articletitled, Successful in vivo purging of CD34-containing peripheral blood harvests in mantle cell and indolent lymphoma: evidence for a role of both chemotherapy and rituximab infusion

The immunophenotype of 177 adults with acute myeloid leukemia: proposal of a prognostic score
Clinical Trials & Observations

Ollivier Legrand,Jean-Yves Perrot,Marion Baudard,Annie Cordier,Régine Lautier,Ghislaine Simonin,Robert Zittoun,Nicole Casadevall,Jean-Pierre Marie

View Articletitled, The immunophenotype of 177 adults with acute myeloid leukemia: proposal of a prognostic score

In vivo generation of human dendritic cell subsets by Flt3 ligand
Clinical Trials & Observations

Eugene Maraskovsky,Elizabeth Daro,Eileen Roux,Mark Teepe,Charlie R. Maliszewski,Jeannie Hoek,Dania Caron,Mel E. Lebsack,Hilary J. McKenna

View Articletitled, In vivo generation of human dendritic cell subsets by Flt3 ligand

GENE THERAPY

Highly efficient gene transfer in naive human T cells with a murine leukemia virus-based vector

Valérie Dardalhon,Sara Jaleco,Cosette Rebouissou,Christophe Ferrand,Nadia Skander,Louise Swainson,Pierre Tiberghien,Hergen Spits,Nelly Noraz,Naomi Taylor

View Articletitled, Highly efficient gene transfer in naive human T cells with a murine leukemia virus-based vector

Inactivation of a GFP retrovirus occurs at multiple levels in long-term repopulating stem cells and their differentiated progeny

Christopher A. Klug,Samuel Cheshier,Irving L. Weissman

View Articletitled, Inactivation of a GFP retrovirus occurs at multiple levels in long-term repopulating stem cells and their differentiated progeny

HEMATOPOIESIS

Enforced P-glycoprotein pump function in murine bone marrow cells results in expansion of side population stem cells in vitro and repopulating cells in vivo

Kevin D. Bunting,Sheng Zhou,Taihe Lu,Brian P. Sorrentino

View Articletitled, Enforced P-glycoprotein pump function in murine bone marrow cells results in expansion of side population stem cells in vitro and repopulating cells in vivo

GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies

Satoru Takahashi,Ritsuko Shimizu,Naruyoshi Suwabe,Takashi Kuroha,Keigyou Yoh,Jun Ohta,Shigeko Nishimura,Kim-Chew Lim,James Douglas Engel,Masayuki Yamamoto

View Articletitled, GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies

Expression of connexin 43 (Cx43) is critical for normal hematopoiesis

Encarnacion Montecino-Rodriguez,Hyosuk Leathers,Kenneth Dorshkind

View Articletitled, Expression of connexin 43 (Cx43) is critical for normal hematopoiesis

Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor

Michael C. Heinrich,Diana J. Griffith,Brian J. Druker,Cecily L. Wait,Kristen A. Ott,Amy J. Zigler

View Articletitled, Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor

JNK and p38 are activated by erythropoietin (EPO) but are not induced in apoptosis following EPO withdrawal in EPO-dependent HCD57 cells

Sarah M. Jacobs-Helber,John J. Ryan,Stephen T. Sawyer

View Articletitled, JNK and p38 are activated by erythropoietin (EPO) but are not induced in apoptosis following EPO withdrawal in EPO-dependent HCD57 cells

A member of Forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phosphatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transduction

Yoshifumi Kashii,Mie Uchida,Keita Kirito,Masaru Tanaka,Kousuke Nishijima,Masaki Toshima,Tomoko Ando,Kazuki Koizumi,Tomoyuki Endoh,Ken-ichi Sawada,Mariko Momoi,Yasusada Miura,Keiya Ozawa,Norio Komatsu

View Articletitled, A member of Forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phosphatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transduction

Mouse Jagged2 is differentially expressed in hematopoietic progenitors and endothelial cells and promotes the survival and proliferation of hematopoietic progenitors by direct cell-to-cell contact

Schickwann Tsai,Jutta Fero,Steve Bartelmez

View Articletitled, Mouse Jagged2 is differentially expressed in hematopoietic progenitors and endothelial cells and promotes the survival and proliferation of hematopoietic progenitors by direct cell-to-cell contact

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

A novel cause of mild/moderate hemophilia A: mutations scattered in the factor VIII C1 domain reduce factor VIII binding to von Willebrand factor

Marc Jacquemin,Renaud Lavend'homme,Abdellah Benhida,Beatrijs Vanzieleghem,Roseline d'Oiron,Jean-Maurice Lavergne,Hans H. Brackmann,Rainer Schwaab,Thierry VandenDriessche,Marinee K. L. Chuah,Marc Hoylaerts,Jean Guy G. Gilles,Kathelijne Peerlinck,Jos Vermylen,Jean-Marie R. Saint-Remy

View Articletitled, A novel cause of mild/moderate hemophilia A: mutations scattered in the factor VIII C1 domain reduce factor VIII binding to von Willebrand factor

Induction of monocyte tissue factor expression by homocysteine: a possible mechanism for thrombosis

Annu Khajuria,Donald S. Houston

View Articletitled, Induction of monocyte tissue factor expression by homocysteine: a possible mechanism for thrombosis

A topological study of the human γ-glutamyl carboxylase

Jianke Tie,Sheue-Mei Wu,Dayun Jin,Christopher V. Nicchitta,Darrel W. Stafford

View Articletitled, A topological study of the human γ-glutamyl carboxylase

Hemophilic factor VIII C1- and C2-domain missense mutations and their modeling to the 1.5-angstrom human C2-domain crystal structure

Miao-Liang Liu,Betty W. Shen,Shelley Nakaya,Kathleen P. Pratt,Kazuo Fujikawa,Earl W. Davie,Barry L. Stoddard,Arthur R. Thompson

View Articletitled, Hemophilic factor VIII C1- and C2-domain missense mutations and their modeling to the 1.5-angstrom human C2-domain crystal structure

The factor XIII V34L polymorphism accelerates thrombin activation of factor XIII and affects cross-linked fibrin structure

Robert A. S. Ariëns,Helen Philippou,Chandrasekaran Nagaswami,John W. Weisel,David A. Lane,Peter J. Grant

View Articletitled, The factor XIII V34L polymorphism accelerates thrombin activation of factor XIII and affects cross-linked fibrin structure

IMMUNOBIOLOGY

Pharmacologic properties of P_2Z/P2X₇receptor characterized in murine dendritic cells: role on the induction of apoptosis

Oscar Kenji Nihei,Antonio Carlos Campos de Carvalho,Wilson Savino,Luiz Anastacio Alves

View Articletitled, Pharmacologic properties of P2Z/P2X7receptor characterized in murine dendritic cells: role on the induction of apoptosis

Interleukin-15 redirects the outcome of a tolerizing T-cell stimulus from apoptosis to anergy

Hans Dooms,Tom Van Belle,Marjory Desmedt,Pieter Rottiers,Johan Grooten

View Articletitled, Interleukin-15 redirects the outcome of a tolerizing T-cell stimulus from apoptosis to anergy

A-myb rescues murine B-cell lymphomas from IgM-receptor–mediated apoptosis through c-myctranscriptional regulation

Marcello Arsura,Claudia S. Hofmann,Josee Golay,Martino Introna,Gail E. Sonenshein

View Articletitled, A-myb rescues murine B-cell lymphomas from IgM-receptor–mediated apoptosis through c-myctranscriptional regulation

CD3ζ and CD28 down-modulation on CD8 T cells during viral infection

Linda A. Trimble,Lawrence W. Kam,Rachel S. Friedman,Zhan Xu,Judy Lieberman

View Articletitled, CD3ζ and CD28 down-modulation on CD8 T cells during viral infection

Caspase-independent commitment phase to apoptosis in activated blood T lymphocytes: reversibility at low apoptotic insult

Céline Dumont,Antoine Dürrbach,Nicolas Bidère,Matthieu Rouleau,Guido Kroemer,Ghislaine Bernard,François Hirsch,Bernard Charpentier,Santos A. Susin,Anna Senik

View Articletitled, Caspase-independent commitment phase to apoptosis in activated blood T lymphocytes: reversibility at low apoptotic insult

The PI3 kinase, p38 SAP kinase, and NF-κB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte–derived dendritic cells

Kirit M. Ardeshna,Arnold R. Pizzey,Stephen Devereux,Asim Khwaja

View Articletitled, The PI3 kinase, p38 SAP kinase, and NF-κB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte–derived dendritic cells

Differential use of FasL- and perforin-mediated cytolytic mechanisms by T-cell subsets involved in graft-versus-myeloid leukemia responses

Michael H. Hsieh,Robert Korngold

View Articletitled, Differential use of FasL- and perforin-mediated cytolytic mechanisms by T-cell subsets involved in graft-versus-myeloid leukemia responses

Functional characterization of an IL-7–dependent CD4⁺CD8αα⁺ Th3-type malignant cell line derived from a patient with a cutaneous T-cell lymphoma

Eva Poszepczynska,Martine Bagot,Hamid Echchakir,Denis Martinvalet,Mohamed Ramez,Dominique Charue,Laurence Boumsell,Armand Bensussan

View Articletitled, Functional characterization of an IL-7–dependent CD4+CD8αα+ Th3-type malignant cell line derived from a patient with a cutaneous T-cell lymphoma

B-cell–autonomous somatic mutation deficit following bone marrow transplant

Annuska M. Glas,Erwin H. N. van Montfort,Jan Storek,Emily-Gene N. Green,Roy P. M. Drissen,Viviane J. Bechtold,J. Zachary Reilly,Monja A. Dawson,Eric C. B. Milner

View Articletitled, B-cell–autonomous somatic mutation deficit following bone marrow transplant

NEOPLASIA

Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance

François Xavier Mahon,Michael W. N. Deininger,Beate Schultheis,Jérome Chabrol,Josy Reiffers,John M. Goldman,Junia V. Melo

View Articletitled, Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance

Plasma levels of the differentiation inhibitory factor nm23-H1 protein and their clinical implications in acute myelogenous leukemia

Nozomi Niitsu,Junko Okabe-Kado,Michihiro Nakayama,Naoki Wakimoto,Akiko Sakashita,Nobuo Maseki,Kazuo Motoyoshi,Masanori Umeda,Yoshio Honma

View Articletitled, Plasma levels of the differentiation inhibitory factor nm23-H1 protein and their clinical implications in acute myelogenous leukemia

Molecular features responsible for the absence of immunoglobulin heavy chain protein synthesis in an IgH⁻ subgroup of multiple myeloma

Tomasz Szczepański,Mars B. van 't Veer,Ingrid L. M. Wolvers-Tettero,Anton W. Langerak,Jacques J. M. van Dongen

View Articletitled, Molecular features responsible for the absence of immunoglobulin heavy chain protein synthesis in an IgH− subgroup of multiple myeloma

TEL/AML1 gene fusion is related to in vitro drug sensitivity forl-asparaginase in childhood acute lymphoblastic leukemia

Nicole L. Ramakers-van Woerden,Rob Pieters,Annemarie H. Loonen,Isabelle Hubeek,Ellen van Drunen,H. Berna Beverloo,Rosalyn M. Slater,Jochen Harbott,Jeanette Seyfarth,Elisabeth R. van Wering,Karel Hählen,Kjeld Schmiegelow,Gritta E. Janka-Schaub,Anjo J. P. Veerman

View Articletitled, TEL/AML1 gene fusion is related to in vitro drug sensitivity forl-asparaginase in childhood acute lymphoblastic leukemia

PHAGOCYTES

LSP1 modulates the locomotion of monocyte-differentiated U937 cells

Yao Li,Qihong Zhang,Rosemary Aaron,Lee Hilliard,Thomas H. Howard

View Articletitled, LSP1 modulates the locomotion of monocyte-differentiated U937 cells

Molecular analysis of 9 new families with chronic granulomatous disease caused by mutations in CYBA, the gene encoding p22^phox

Julie Rae,Deborah Noack,Paul G. Heyworth,Beverly A. Ellis,John T. Curnutte,Andrew R. Cross

View Articletitled, Molecular analysis of 9 new families with chronic granulomatous disease caused by mutations in CYBA, the gene encoding p22phox

RED CELLS

The molecular defect in hypotransferrinemic mice

Cameron C. Trenor, III,Dean R. Campagna,Vera M. Sellers,Nancy C. Andrews,Mark D. Fleming

View Articletitled, The molecular defect in hypotransferrinemic mice

Fetal hemoglobin in sickle cell disease: relationship to erythrocyte phosphatidylserine exposure and coagulation activation

B. N. Yamaja Setty,Surekha Kulkarni,A. Koneti Rao,Marie J. Stuart

View Articletitled, Fetal hemoglobin in sickle cell disease: relationship to erythrocyte phosphatidylserine exposure and coagulation activation

Wild-type HFE protein normalizes transferrin iron accumulation in macrophages from subjects with hereditary hemochromatosis

Giuliana Montosi,Paola Paglia,Cinzia Garuti,Carlos A. Guzman,Judy M. Bastin,Mario P. Colombo,Antonello Pietrangelo

View Articletitled, Wild-type HFE protein normalizes transferrin iron accumulation in macrophages from subjects with hereditary hemochromatosis

Triose phosphate isomerase deficiency in 3 French families: two novel null alleles, a frameshift mutation (TPI Alfortville) and an alteration in the initiation codon (TPI Paris)

Colette Valentin,Serge Pissard,Josiane Martin,Delphine Héron,Philippe Labrune,Marie-Odile Livet,Michèle Mayer,Terri Gelbart,Arthur Schneider,Isabelle Max-Audit,Michel Cohen-Solal

View Articletitled, Triose phosphate isomerase deficiency in 3 French families: two novel null alleles, a frameshift mutation (TPI Alfortville) and an alteration in the initiation codon (TPI Paris)

The human ankyrin-1 gene is selectively transcribed in erythroid cell lines despite the presence of a housekeeping-like promoter

Patrick G. Gallagher,Marc Romana,William T. Tse,Samuel E. Lux,Bernard G. Forget

View Articletitled, The human ankyrin-1 gene is selectively transcribed in erythroid cell lines despite the presence of a housekeeping-like promoter

TRANSFUSION MEDICINE

Recipient elimination of allogeneic lymphoid cells: donor CD4⁺ cells are effective alloantigen-presenting cells

Loren D. Fast

View Articletitled, Recipient elimination of allogeneic lymphoid cells: donor CD4+ cells are effective alloantigen-presenting cells

TRANSPLANTATION

Graft-versus-host disease and donor-directed hemagglutinin titers after ABO-mismatched related and unrelated marrow allografts: evidence for a graft-versus-plasma cell effect

Marco Mielcarek,Wendy Leisenring,Beverly Torok-Storb,Rainer Storb

View Articletitled, Graft-versus-host disease and donor-directed hemagglutinin titers after ABO-mismatched related and unrelated marrow allografts: evidence for a graft-versus-plasma cell effect

Molecular modification of a recombinant anti-CD3ε-directed immunotoxin by inducing terminal cysteine bridging enhances anti-GVHD efficacy and reduces organ toxicity in a lethal murine model

Daniel A. Vallera,David W. Kuroki,Angela Panoskaltsis-Mortari,Donald J. Buchsbaum,Buck E. Rogers,Bruce R. Blazar

View Articletitled, Molecular modification of a recombinant anti-CD3ε-directed immunotoxin by inducing terminal cysteine bridging enhances anti-GVHD efficacy and reduces organ toxicity in a lethal murine model

A novel application of cyclosporine A in nonmyeloablative pretransplant host conditioning for allogeneic BMT
Clinical Trials & Observations

Boris Nikolic,Guiling Zhao,Kirsten Swenson,Megan Sykes

View Articletitled, A novel application of cyclosporine A in nonmyeloablative pretransplant host conditioning for allogeneic BMT

BRIEF REPORTS

Therapeutic levels of human factor VIII and IX using HIV-1–based lentiviral vectors in mouse liver
Brief Report

Frank Park,Kazuo Ohashi,Mark A. Kay

View Articletitled, Therapeutic levels of human factor VIII and IX using HIV-1–based lentiviral vectors in mouse liver

α-Fibrinogen Thr312Ala polymorphism and venous thromboembolism
Brief Report

Angela M. Carter,Andrew J. Catto,Hans P. Kohler,Robert A. S. Ariëns,Max H. Stickland,Peter J. Grant

View Articletitled, α-Fibrinogen Thr312Ala polymorphism and venous thromboembolism

Splenectomy selectively affects the distribution and mobility of the recirculating lymphocyte pool
Brief Report

Tim J. Seabrook,Wayne R. Hein,Lisbeth Dudler,Alan J. Young

View Articletitled, Splenectomy selectively affects the distribution and mobility of the recirculating lymphocyte pool

Pure red cell aplasia due to parvovirus B19 in a patient treated with rituximab
Brief Report

Vivek R. Sharma,Donald R. Fleming,Stephen P. Slone

View Articletitled, Pure red cell aplasia due to parvovirus B19 in a patient treated with rituximab

Ligation of the CD44 adhesion molecule inhibits drug-induced apoptosis in human myeloid leukemia cells
Brief Report

Michèle Allouche,Rachida Sihem Charrad,Ali Bettaieb,Catherine Greenland,Cécile Grignon,Florence Smadja-Joffe

View Articletitled, Ligation of the CD44 adhesion molecule inhibits drug-induced apoptosis in human myeloid leukemia cells

Familial thrombophilia associated with fibrinogen Paris V: Dusart syndrome
Brief Report

Takashi Tarumi,Danko Martincic,Anne Thomas,Robert Janco,Mary Hudson,Patricia Baxter,David Gailani

View Articletitled, Familial thrombophilia associated with fibrinogen Paris V: Dusart syndrome

CORRESPONDENCE

Cytomegalovirus infection following transplantation of autologous CD34-selected progenitor cells
Clinical Trials & Observations

Gary John Schiller,Robert Vescio,James Berenson

View Articletitled, Cytomegalovirus infection following transplantation of autologous CD34-selected progenitor cells

Cyclosporine (CSP) or CSP plus methylprednisolone for graft-versus-host-disease prophylaxis in patients with high-risk lymphohemopoietic malignancies: long-term follow-up of a randomized trial
Clinical Trials & Observations

H. Joachim Deeg,Mary E. D. Flowers,Wendy Leisenring,Frederick R. Appelbaum,Paul J. Martin,Rainer F. Storb

View Articletitled, Cyclosporine (CSP) or CSP plus methylprednisolone for graft-versus-host-disease prophylaxis in patients with high-risk lymphohemopoietic malignancies: long-term follow-up of a randomized trial

10

The limitations of site-directed mutagenesis in the localization of Rh D epitopes

Tylis Y. Chang,Don L. Siegel

View Articletitled, The limitations of site-directed mutagenesis in the localization of Rh D epitopes

17

A potential role for leukemia inhibitory factor in the increased clonogenicity of human fetal progenitor cells

Peter Kurre,Stefan Burdach

View Articletitled, A potential role for leukemia inhibitory factor in the increased clonogenicity of human fetal progenitor cells

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Issue Archive

Table of Contents

PLENARY PAPERS

ERRATA

REVIEW ARTICLES

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Heparin-induced thrombocytopenia with thromboembolic complications: meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range Clinical Trials & Observations

Prognostic factors in Waldenström macroglobulinemia: a report on 232 patients with the description of a new scoring system and its validation on 253 other patients Clinical Trials & Observations

Constitutive elevation of serum alpha-fetoprotein in Fanconi anemia Clinical Trials & Observations

Successful in vivo purging of CD34-containing peripheral blood harvests in mantle cell and indolent lymphoma: evidence for a role of both chemotherapy and rituximab infusion Clinical Trials & Observations

The immunophenotype of 177 adults with acute myeloid leukemia: proposal of a prognostic score Clinical Trials & Observations

In vivo generation of human dendritic cell subsets by Flt3 ligand Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

IMMUNOBIOLOGY

NEOPLASIA

PHAGOCYTES

RED CELLS

TRANSFUSION MEDICINE

TRANSPLANTATION

A novel application of cyclosporine A in nonmyeloablative pretransplant host conditioning for allogeneic BMT Clinical Trials & Observations

BRIEF REPORTS

Therapeutic levels of human factor VIII and IX using HIV-1–based lentiviral vectors in mouse liver Brief Report

α-Fibrinogen Thr312Ala polymorphism and venous thromboembolism Brief Report

Splenectomy selectively affects the distribution and mobility of the recirculating lymphocyte pool Brief Report

Pure red cell aplasia due to parvovirus B19 in a patient treated with rituximab Brief Report

Ligation of the CD44 adhesion molecule inhibits drug-induced apoptosis in human myeloid leukemia cells Brief Report

Familial thrombophilia associated with fibrinogen Paris V: Dusart syndrome Brief Report