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Journal Articles

Prevention of Hemophagocytosis by TNF-α and IL-6 Blockade in TLR9- and Nod1- Ligand Induced Hemophagocytic Syndrome.

Hideaki Ohyagi, MD, Nobuyuki Onai, PhD, Yong-Mei Guo, MD, Naoto Takahashi, MD, PhD, Makoto Hirokawa, MD, PhD, Ken-Ichi Sawada, MD, PhD, Toshiaki Ohteki, PhD

Blood (2009) 114 (22): 1351.

https://doi.org/10.1182/blood.V114.22.1351.1351

Published: 2009

Journal Articles

Aberrant Overexpressions of MicroRNA-21 and MicroRNA-155 Activate AKT Signaling Via Downregulation of Tumor Suppressors in NK-Cell Lymphoma/Leukemia.

Hiroyuki Tagawa, M.D., Ph.D., Yasuo Yamanaka, M.D., Atsushi Watanabe, M.D., Naoto Takahashi, M.D., Ph.D., Ken-ichi Sawada, M.D., Ph.D.

Blood (2009) 114 (22): 1917.

https://doi.org/10.1182/blood.V114.22.1917.1917

Published: 2009

Journal Articles

Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer–cell lymphoma/leukemia

Yasuo Yamanaka, Hiroyuki Tagawa, Naoto Takahashi, Atsushi Watanabe, Yong-Mei Guo, Keiko Iwamoto, Junsuke Yamashita, Hirobumi Saitoh, Yoshihiro Kameoka, Norio Shimizu, Ryo Ichinohasama, Ken-ichi Sawada

Blood (2009) 114 (15): 3265–3275.

https://doi.org/10.1182/blood-2009-06-222794

Published: 2009

Includes: Supplemental data

Journal Articles

Impact of Decrease of Serum Haptoglobin in Patients with Acquired Bone Marrow Failure Syndromes

Hideyoshi Noji, MD, PhD, Kazuhiko Ikeda, MD, PhD, Naoto Takahashi, MD, PhD, Junichi Kameoka, MD, PhD, Katsushi Tajima, MD, PhD, Kazunori Murai, MD, PhD, Yoshiko Tamai, MD, PhD, Toyomi Kamesaki, MD, PhD, Yasuchika Takeishi, MD, PhD, Ken-Ichi Sawada, MD, PhD, Tsutomu Shichishima, MD, PhD

Blood (2008) 112 (11): 4111.

https://doi.org/10.1182/blood.V112.11.4111.4111

Published: 2008

Journal Articles

Acquired Pure Red Cell Aplasia Associated with Malignant Lymphomas: A Nationwide Cohort Study in Japan

Makoto Hirokawa, Ken-ichi Sawada, Naohito Fujishima, Fumio Kawano, Akiro Kimura, Takashi Watanabe, Ayako Arai, Toshimitsu Matsui, Shinji Nakao, Akio Urabe, Mitsuhiro Omine, Keiya Ozawa

Blood (2008) 112 (11): 4112.

https://doi.org/10.1182/blood.V112.11.4112.4112

Published: 2008

Journal Articles

Low Level of Serum Haptoglobin in Patients with Acquired Bone Marrow Failure (BMF) Syndromes.

Kazuhiko Ikeda, MD, PhD, Naoto Takahashi, MD, PhD, Junichi Kameoka, MD, PhD, Katsushi Tajima, MD, PhD, Kazunori Murai, MD, PhD, Yoshiko Tamai, Hideyoshi Noji, MD, PhD, Yoji Ishida, MD, PhD, Ken-Ichi Sawada, MD, PhD, Tsutomu Shichishima, MD, PhD

Blood (2007) 110 (11): 3774.

https://doi.org/10.1182/blood.V110.11.3774.3774

Published: 2007

Journal Articles

Responses and Outcome Following Immunosuppressive Therapy in Large Granular Lymphocyte Leukemia-Associated Pure Red Cell Aplasia: A Nationwide Cohort Study in Japan for the PRCA Collaborative Study Group.

Naohito Fujishima, Ken-ichi Sawada, Makoto Hirokawa, Kazuo Oshimi, Akira Matsuda, Masanao Teramura, Masamitsu Karasawa, Shinji Nakao, Akio Urabe, Mitsuhiro Omine, Keiya Ozawa

Blood (2007) 110 (11): 1688.

https://doi.org/10.1182/blood.V110.11.1688.1688

Published: 2007

Journal Articles

Diagnostic Significance of Haptoglobin Concentration in Patients with Bone Marrow Failure Syndromes.

Kazuhiko Ikeda, MD, PhD, Naoto Takahashi, MD,PhD, Junichi Kameoka, MD,PhD, Katsushi Tajima, MD,PhD, Akiko Nakamura, MD,PhD, Sayuri Mizuno, MT, Takeshi Sasaki, MD,PhD, Ken-Ichi Sawada, MD,PhD, Yukio Maruyama, MD,PhD, Tsutomu Shichishima, MD,PhD

Blood (2006) 108 (11): 3772.

https://doi.org/10.1182/blood.V108.11.3772.3772

Published: 2006

Journal Articles

Possible Protective Role for Vδ1+ γδT Lymphocytes in Epstein-Barr Virus Infection after Allogeneic Hematopoietic Stem Cell Transplantation.

Masumi Fujishima, MD, Makoto Hirokawa, MD, Naohito Fujishima, MD, Junsuke Yamashita, Hirobumi Saitoh, MD, Yoshikazu Ichikawa, MD, Takahiro Horiuchi, MD, Yoshinari Kawabata, MD, Ken-ichi Sawada, MD

Blood (2006) 108 (11): 3225.

https://doi.org/10.1182/blood.V108.11.3225.3225

Published: 2006

Journal Articles

Long-Term Relapse-Free Survival and Overall Survival of Patients with Acquired Primary Idiopathic Pure Red Cell Aplasia Receiving Cyclosporine: A Nationwide Cohort Study in Japan for the PRCA Collaborative Study Group.

Ken-ichi Sawada, MD, Makoto Hirokawa, MD, Naohito Fujishima, MD, Shinji Nakao, MD, Akio Urabe, MD, Mitsuhiro Omine, MD, Keiya Ozawa, MD

Blood (2006) 108 (11): 1294.

https://doi.org/10.1182/blood.V108.11.1294.1294

Published: 2006

Journal Articles

Responses and Outcome of Immunosuppressive Therapy in Thymoma-Associated Pure Red Cell Aplasia: A Nationwide Cohort Study in Japan for the PRCA Collaborative Study Group.

Makoto Hirokawa, MD, Ken-ichi Sawada, MD, Naohito Fujishima, MD, Shinji Nakao, MD, Akio Urabe, MD, Mitsuhiro Omine, MD, Keiya Ozawa, MD

Blood (2006) 108 (11): 653.

https://doi.org/10.1182/blood.V108.11.653.653

Published: 2006

Journal Articles

Phagocytosis of Co-Developing Neutrophil Progenitors by Dendritic Cells in Culture with Granulocyte-Colony Stimulating-Factor and Tumor Necrosis Factor-α: Induction of T Regulatory Cells by Co-Developing Dendritic Cells.

Yoshinobu Saito, MD, Makoto Hirokawa, MD, Kunie Saito, MD, Yong-Mei Guo, MD, Miwa Hebiguchi, MD, Yoshinari Kawabata, MD, Atsushi Komatsuda, MD, Naoto Takahashi, MD, Junsuke Yamashita, Ken-ichi Sawada, MD

Blood (2006) 108 (11): 1720.

https://doi.org/10.1182/blood.V108.11.1720.1720

Published: 2006

Journal Articles

Enucleation of Human Erythroblasts Is a Process of Asymmetric Cytokinesis.

Miwa Hebiguchi, Makoto Hirokawa, Yong-Mei Guo, Yoshinari Kawabata, Atsushi Komatsuda, Takehiko Sasaki, Yuichi Takakuwa, Ken-ichi Sawada

Blood (2006) 108 (11): 1663.

https://doi.org/10.1182/blood.V108.11.1663.1663

Published: 2006

Journal Articles

A Nationwide Survey of Immunosuppressive Therapy for Idiopathic Acquired Pure Red Cell Aplasia in Japan and a Proposal for First-Line Treatment: Report of the PRCA Collaborative Study Group.

Makoto Hirokawa, MD, Ken-ichi Sawada, MD, Mutsuhito Motegi, MD, Shigeo Mamiya, MD, Masanao Teramura, MD, Shinji Nakao, MD, Keiya Ozawa, MD, Akio Urabe, MD, Mitsuhiro Omine, MD

Blood (2005) 106 (11): 3747.

https://doi.org/10.1182/blood.V106.11.3747.3747

Published: 2005

Journal Articles

Skewed TCR Repertoire of Vδ1+ γδT Cells in Recipients of Allogeneic Hematopoietic Stem Cell Grafts and Possible Involvement of Epstein-Barr Virus in Clonal Expansion of Vδ1+ T Cells.

Masumi Fujishima, MD, Makoto Hirokawa, MD, Naohito Fujishima, MD, Hirobumi Saitoh, MD, Yoshikazu Ichikawa, MD, Yoshinari Kawabata, MD, Ikuo Miura, MD, Ken-ichi Sawada, MD

Blood (2004) 104 (11): 2230.

https://doi.org/10.1182/blood.V104.11.2230.2230

Published: 2004

Journal Articles

Oligoclonal Expansion of Vδ1+ γδT Cells in Cyclosporine-Responsive Acquired Pure Red Cell Aplasia.

Makoto Hirokawa, MD, Naohito Fujishima, MD, Yuhta Oyama, MD, Masumi Fujishima, MD, Takahiro Horiuchi, MD, Atsushi Kitabayashi, MD, Ikuo Miura, MD, Ken-ichi Sawada, MD

Blood (2004) 104 (11): 3845.

https://doi.org/10.1182/blood.V104.11.3845.3845

Published: 2004

Journal Articles

Expression of Human Enhancer of Invasion 10 (HEI10) in Human Myeloid Leukemias and Downregulation during Differentiation of Hematopoietic Stem Cells.

Naohito Fujishima, MD, Makoto Hirokawa, MD, Masumi Fujishima, MD, Yoshikazu Ichikawa, MD, Takahiro Horiuchi, MD, Ikuo Miura, MD, Ken-ichi Sawada, MD

Blood (2004) 104 (11): 4290.

https://doi.org/10.1182/blood.V104.11.4290.4290

Published: 2004

Journal Articles

Dendritic Cells Co-Developing from Human CD34+ Cells Following Incubation with Thrombopoietin and Tumor Necrosis Factor-α Phagocytose Self-Megakaryocytic Progenitors and Induce Autologous T-Cell Proliferation.

Kunie Saito, MD, Makoto Hirokawa, MD, Hiroshi Fukaya, MD, Yoshinari Kawabata, MD, AtAtsushi Komatsuda, MD, JuJunsuke Yamashita, Ken-Ichi Sawada, MD

Blood (2004) 104 (11): 4132.

https://doi.org/10.1182/blood.V104.11.4132.4132

Published: 2004

Journal Articles

Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis

Mitsujiro Osawa, Tomoyuki Yamaguchi, Yukio Nakamura, Shin Kaneko, Masafumi Onodera, Ken-ichi Sawada, Armin Jegalian, Hong Wu, Hiromitsu Nakauchi, Atsushi Iwama

Blood (2002) 100 (8): 2769–2777.

https://doi.org/10.1182/blood-2002-01-0182

Published: 2002

Journal Articles

A member of Forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phosphatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transduction

Yoshifumi Kashii, Mie Uchida, Keita Kirito, Masaru Tanaka, Kousuke Nishijima, Masaki Toshima, Tomoko Ando, Kazuki Koizumi, Tomoyuki Endoh, Ken-ichi Sawada, Mariko Momoi, Yasusada Miura, Keiya Ozawa, Norio Komatsu

Blood (2000) 96 (3): 941–949.

https://doi.org/10.1182/blood.V96.3.941

Published: 2000

NARROW

Prevention of Hemophagocytosis by TNF-α and IL-6 Blockade in TLR9- and Nod1- Ligand Induced Hemophagocytic Syndrome.

Aberrant Overexpressions of MicroRNA-21 and MicroRNA-155 Activate AKT Signaling Via Downregulation of Tumor Suppressors in NK-Cell Lymphoma/Leukemia.

Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer–cell lymphoma/leukemia

Impact of Decrease of Serum Haptoglobin in Patients with Acquired Bone Marrow Failure Syndromes

Acquired Pure Red Cell Aplasia Associated with Malignant Lymphomas: A Nationwide Cohort Study in Japan

Low Level of Serum Haptoglobin in Patients with Acquired Bone Marrow Failure (BMF) Syndromes.

Responses and Outcome Following Immunosuppressive Therapy in Large Granular Lymphocyte Leukemia-Associated Pure Red Cell Aplasia: A Nationwide Cohort Study in Japan for the PRCA Collaborative Study Group.

Diagnostic Significance of Haptoglobin Concentration in Patients with Bone Marrow Failure Syndromes.

Possible Protective Role for Vδ1+ γδT Lymphocytes in Epstein-Barr Virus Infection after Allogeneic Hematopoietic Stem Cell Transplantation.

Long-Term Relapse-Free Survival and Overall Survival of Patients with Acquired Primary Idiopathic Pure Red Cell Aplasia Receiving Cyclosporine: A Nationwide Cohort Study in Japan for the PRCA Collaborative Study Group.

Responses and Outcome of Immunosuppressive Therapy in Thymoma-Associated Pure Red Cell Aplasia: A Nationwide Cohort Study in Japan for the PRCA Collaborative Study Group.

Phagocytosis of Co-Developing Neutrophil Progenitors by Dendritic Cells in Culture with Granulocyte-Colony Stimulating-Factor and Tumor Necrosis Factor-α: Induction of T Regulatory Cells by Co-Developing Dendritic Cells.

Enucleation of Human Erythroblasts Is a Process of Asymmetric Cytokinesis.

A Nationwide Survey of Immunosuppressive Therapy for Idiopathic Acquired Pure Red Cell Aplasia in Japan and a Proposal for First-Line Treatment: Report of the PRCA Collaborative Study Group.

Skewed TCR Repertoire of Vδ1+ γδT Cells in Recipients of Allogeneic Hematopoietic Stem Cell Grafts and Possible Involvement of Epstein-Barr Virus in Clonal Expansion of Vδ1+ T Cells.

Oligoclonal Expansion of Vδ1+ γδT Cells in Cyclosporine-Responsive Acquired Pure Red Cell Aplasia.

Expression of Human Enhancer of Invasion 10 (HEI10) in Human Myeloid Leukemias and Downregulation during Differentiation of Hematopoietic Stem Cells.

Dendritic Cells Co-Developing from Human CD34+ Cells Following Incubation with Thrombopoietin and Tumor Necrosis Factor-α Phagocytose Self-Megakaryocytic Progenitors and Induce Autologous T-Cell Proliferation.

Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis

A member of Forkhead family transcription factor, FKHRL1, is one of the downstream molecules of phosphatidylinositol 3-kinase-Akt activation pathway in erythropoietin signal transduction

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American Society of Hematology

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American Society of Hematology

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