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Journal Articles

Favorable Outcomes of Newly Diagnosed Intravascular Large B-Cell Lymphoma Patients Treated with R-CHOP Combined with High-Dose Methotrexate Plus Intrathecal Chemotherapy: Results from a Multicenter Phase 2 Trial (PRIMEUR-IVL)

Kazuyuki Shimada, MD, Motoko Yamaguchi, MD PhD, Yoshiko Atsuta, MD PhD, Kosei Matsue, MD PhD, Keijiro Sato, MD, Shigeru Kusumoto, MD PhD, Hirokazu Nagai, MD PhD, Jun Takizawa, MD PhD, Noriko Fukuhara, MD PhD, Koji Nagafuji, MD PhD, Kana Miyazaki, MD PhD, Eiichi Ohtsuka, MD, Masataka Okamoto, MD PhD, Yasumasa Sugita, MD PhD, Toshiki Uchida, MD PhD, Satoshi Kayukawa, MD, Atsushi Wake, MD PhD, Daisuke Ennishi, MD PhD, Yukio Kondo, MD, Tohru Izumi, MD, Yoshihiro Kin, MD, Kunihiro Tsukasaki, MD PhD, Daigo Hashimoto, Masaaki Yuge, MD PhD, Atsumi Yanagisawa, Yachiyo Kuwatsuka, MD PhD, Satoko Shimada, MD, Yasufumi Masaki, MD PhD, Nozomi Niitsu, MD PhD, Hitoshi Kiyoi, MD PhD, Ritsuro Suzuki, MD PhD, Takashi Tokunaga, MD PhD, Shigeo Nakamura, MD, Tomohiro Kinoshita, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 350.
https://doi.org/10.1182/blood-2019-126798
Published: 2019
Journal Articles

Improved Prognosis of Extranodal NK/T-Cell Lymphoma, Nasal Type (ENKL) of Nasal Origin but Not Extranasal Origin: An Analysis of NKEA Study

Motoko Yamaguchi, MDPhD, Ritsuro Suzuki, MD PhD, Kana Miyazaki, MD PhD, Jun Amaki, MD PhD, Jun Takizawa, MD PhD, Nodoka Sekiguchi, MD, Shiori Inagaki, MD PhD, Naoto Tomita, MD PhD, Hideho Wada, MD PhD, Yukio Kobayashi, MD PhD, Nozomi Niitsu, MD PhD, Toshihiko Ando, MD PhD, Takeshi Maeda, MD PhD, Bungo Saito, MD PhD, Hiroshi Matsuoka, MD PhD, Rika Sakai, MD PhD, Nobuko Kubota, MD PhD, Yasufumi Masaki, MD PhD, Naoko Asano, MD PhD, Masahiko Oguchi, MD PhD, Naoyuki Katayama, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1518.
https://doi.org/10.1182/blood.V130.Suppl_1.1518.1518
Published: 2017
Journal Articles

Dose-Adjusted (DA) - EPOCH-R with High-Dose Methotrexate for Newly Diagnosed CD5-Positive Diffuse Large B-Cell Lymphoma (CD5+ DLBCL): Interim Results from a Phase II Study

Kana Miyazaki, MD PhD, Naoko Asano, MD PhD, Tomomi Yamada, PhD, Hirotaka Takasaki, MD PhD, Tadahiko Igarashi, MD PhD, Momoko Nishikori, MD PhD, Kinya Ohata, MD PhD, Kazutaka Sunami, MD PhD, Isao Yoshida, MD PhD, Nozomi Niitsu, MD PhD, Masataka Okamoto, MD PhD, Hiroki Yano, MD PhD, Yuki Nishimura, PhD, Satoshi Tamaru, MD PhD, Koji Izutsu, MD PhD, Tomohiro Kinoshita, MD PhD, Junji Suzumiya, MD PhD, Masakatsu Nishikawa, MD PhD, Naoyuki Katayama, MD PhD, Motoko Yamaguchi, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3029.
https://doi.org/10.1182/blood.V128.22.3029.3029
Published: 2016
Journal Articles

Prognostic Significance of EBV Association in Diffuse Large B-Cell Lymphoma in the Rituximab Era

Nozomi Niitsu, MDPhD, Naoki Takahashi, Tadashi Yoshino, MD PhD, Masataka Okamoto, MD PhD, Shigeo Nakamura, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3911.
https://doi.org/10.1182/blood.V126.23.3911.3911
Published: 2015
Journal Articles

Clinicopathological Features and Prognosis of B-Cell Lymphoma, Unclassifiable, with Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma with t(14;18) and 8q24 Translocation in the Rituximab Era

Nozomi Niitsu, MD, PhD, Naoki Takahashi, Mika Kohri, Norio Asou, MD PhD, Jun-ichi Tamaru, Jun Sakai, Shigeo Nakamura, Ikuo Miura, Masataka Okamoto
Journal: Blood
Blood (2014) 124 (21): 1633.
https://doi.org/10.1182/blood.V124.21.1633.1633
Published: 2014
Journal Articles

Novel Prognostic Model Of Primary Mediastinal Large B-Cell Lymphoma (PMBL): A Multicenter Cooperative Retrospective Study In Japan

Tomohiro Aoki, M.D., Koji Izutsu, MD, PhD, Ritsuro Suzuki, MD, Chiaki Nakaseko, M.D., Ph.D., Hiroshi Arima, M.D., Kazuyuki Shimada, M.D., Ph.D., Makoto Sasaki, M.D., Ph.D., Jun Takizawa, M.D., Ph.D., Kinuko Mitani, M.D., Ph.D., Tadahiko Igarashi, M.D., Yoshinobu Maeda, M.D., Ph.D., Fumihiro Ishida, M.D., Nozomi Niitsu, M.D., Ph.D., Ken Ohmachi, M.D., Hirotaka Takasaki, M.D., Naoya Nakamura, M.D., Ph.D., Tomohiro Kinoshita, MD, PhD, Shigeo Nakamura, MD, PhD, Michinori Ogura, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 638.
https://doi.org/10.1182/blood.V122.21.638.638
Published: 2013
Journal Articles

A Study on nm23-H1 Expression in Hodgkin Lymphoma That Was Treated with BEACOPP Therapy

Nozomi Niitsu, Kumiko Yoshitake, Hirokazu Nakamine, Masataka Okamoto
Journal: Blood
Blood (2011) 118 (21): 4861.
https://doi.org/10.1182/blood.V118.21.4861.4861
Published: 2011
Journal Articles

Hepatic toxicity and prognosis in hepatitis C virus–infected patients with diffuse large B-cell lymphoma treated with rituximab-containing chemotherapy regimens: a Japanese multicenter analysis

Clinical Trials & Observations
Daisuke Ennishi, Yoshinobu Maeda, Nozomi Niitsu, Minoru Kojima, Koji Izutsu, Jun Takizawa, Shigeru Kusumoto, Masataka Okamoto, Masahiro Yokoyama, Yasushi Takamatsu, Kazutaka Sunami, Akira Miyata, Kayoko Murayama, Akira Sakai, Morio Matsumoto, Katsuji Shinagawa, Akinobu Takaki, Keitaro Matsuo, Tomohiro Kinoshita, Mitsune Tanimoto
Journal: Blood
Blood (2010) 116 (24): 5119–5125.
https://doi.org/10.1182/blood-2010-06-289231
Published: 2010
Includes: Supplemental data
Journal Articles

Clinical Significance of Immunohistochemical Markers of Diffuse Large B-Cell Lymphoma In the Rituximab Era.

Miyuki Hayama, Masataka Okamoto, MD, PhD, Yuki Hagiwara, Ken Tanae, Mika Kohri, Naoki Takahashi, Tadashi Yoshino, Koichi Ohshima, Nozomi Niitsu, MD
Journal: Blood
Blood (2010) 116 (21): 1800.
https://doi.org/10.1182/blood.V116.21.1800.1800
Published: 2010
Journal Articles

Prospective Analysis of Hepatitis B Virus Reactivation In Patients with Diffuse Large B Cell Lymphoma After Rituximab Combination Chemotherapy

Nozomi Niitsu, MD, Yuki Hagiwara, Ken Tanae, Mika Kohri, Miyuki Hayama, MD, PhD, Naoki Takahashi
Journal: Blood
Blood (2010) 116 (21): 3950.
https://doi.org/10.1182/blood.V116.21.3950.3950
Published: 2010
Journal Articles

Clinicopathological Features of Nodular Sclerosis-Type Classical Hodgkin Lymphoma In the Elderly: Multicenter Study of Hodgkin Lymphoma In Japan

Naoko Asano, MD, Tomohiro Kinoshita, MD, PhD, Koichi Ohshima, MD, Tadashi Yoshino, MD, Nozomi Niitsu, MD, Norifumi Tsukamoto, MD, PhD, Kaoru Hirabayashi, MD, Koji Izutsu, MD, Yasuo Morishima, MD, PhD, Tadashi Matsushita, MD, PhD, Shigeo Nakamura, MD
Journal: Blood
Blood (2010) 116 (21): 2677.
https://doi.org/10.1182/blood.V116.21.2677.2677
Published: 2010
Journal Articles

Multicenter Phase II Study of the CyclOBEAP Regimen for Patients with Peripheral T-Cell Lymphoma with Analysis of Biomakers.

Nozomi Niitsu, MD, PhD, Miyuki Hayama, MD, PhD, Yuki Hagiwara, Ken Tanae, Mika Kohri, Naoki Takahashi, Shigeo Nakamura, MD, Jun-ichi Tamaru, Masataka Okamoto, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2795.
https://doi.org/10.1182/blood.V116.21.2795.2795
Published: 2010
Journal Articles

Multicenter Phase II Study of the CyclOBEAP Plus Rituximab in Diffuse Large B-Cell Lymphoma with Analysis of Biomakers.

Nozomi Niitsu, Mika Kohri, Yuki Hagiwara, Ken Tanae, Handa Kohsuke, Naoki Takahashi, Masami Bessho, Masataka Okamoto
Journal: Blood
Blood (2009) 114 (22): 2725.
https://doi.org/10.1182/blood.V114.22.2725.2725
Published: 2009
Journal Articles

The Impact of Outcome and Hepatic Toxicity in HCV-Infected Patients with Diffuse Large B-Cell Lymphoma Treated with Rituximab Plus CHOP Therapy; A Retrospective Multicenter Japanese Analysis.

Daisuke Ennishi, Yoshinobu Maeda, Nozomi Niitsu, Minoru Kojima, Koji Izutsu, Jun Takizawa, Shigeru Kusumoto, Masataka Okamoto, Masahiro Yokoyama, Yasushi Takamatsu, Kazutaka Sunami, Akira Miyata, Kayoko Murayama, Akira Sakai, Morio Matsumoto, Katsuji Shinagawa, Akinobu Takaki, Keitaro Matsuo, Tomohiro Kinoshita, Mitsune Tanimoto
Journal: Blood
Blood (2009) 114 (22): 2700.
https://doi.org/10.1182/blood.V114.22.2700.2700
Published: 2009
Journal Articles

Evaluation of Central Nervous System Recurrence of Intravascular Large B-Cell Lymphoma Treated with Rituximab-Containing Chemotherapy

Kazuyuki Shimada, MD, Takuhei Murase, MD, Kosei Matsue, MD, Masataka Okamoto, MD, Naoaki Ichikawa, MD, Norifumi Tsukamoto, MD, PhD, Ako Kikuchi, MD, Yoshio Saburi, MD, Yasufumi Masaki, MD, PhD, Nozomi Niitsu, MD, Hiroshi Miwa, MD, Hideki Asaoku, MD, Hiroshi Kosugi, MD, PhD, Morio Matsumoto, MD, Makoto Kashimura, MD, Takashi Yoshida, MD, Kazuo Tamura, MD, Kazuhito Yamamoto, MD, Motoko Yamaguchi, MD, PhD, Shigeo Nakamura, MD, Tomoki Naoe, MD, Tomohiro Kinoshita, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 4933.
https://doi.org/10.1182/blood.V112.11.4933.4933
Published: 2008
Journal Articles

Improved Survival of Intravascular Large B-Cell Lymphoma (IVLBCL) by Rituximab Containing Combination Chemotherapies.

Kazuyuki Shimada, Kosei Matsue, Kazuhito Yamamoto, Naoaki Ichikawa, Masataka Okamoto, Nozomi Niitsu, Hiroshi Kosugi, Norifumi Tsukamoto, Takuhei Murase, Hiroshi Miwa, Hideki Asaoku, Ako Kikuchi, Morio Matsumoto, Yoshio Saburi, Yasufumi Masaki, Makoto Kashimura, Motoko Yamaguchi, Shigeo Nakamura, Tomoki Naoe, Kinoshita Tomohiro
Journal: Blood
Blood (2007) 110 (11): 3439.
https://doi.org/10.1182/blood.V110.11.3439.3439
Published: 2007
Journal Articles

Prognostic Impact of Chromosomal Alterations of 3q27 on B-Cell Lymphoma.

Nozomi Niitsu, Masataka Okamoto, Naoya Nakamura, Sadao Aoki, Masami Bessho, Masami Hirano, Ikuo Miura
Journal: Blood
Blood (2005) 106 (11): 2836.
https://doi.org/10.1182/blood.V106.11.2836.2836
Published: 2005
Journal Articles

Treatment Outcome of Aggressive Lymphoma with CyclOBEAP (CHOP-Like + Etoposide and Bleomycin): Results of Multicenter Trial.

Masataka Okamoto, M.D., Nozomi Niitsu, M.D., Sadao Aoki, M.D., Yasunobu Kuraishi, M.D., Hirokazu Okumura, M.D., Masami Hirano, M.D.
Journal: Blood
Blood (2004) 104 (11): 3303.
https://doi.org/10.1182/blood.V104.11.3303.3303
Published: 2004
Journal Articles

Phase I/II Study of the Rituximab-EPOCT Regimen in Combination with G-CSF in Patients with Relapsed or Refractory Follicular Lymphoma Including Evaluation of Its Cardiotoxicity Using B-Type Natriuretic Peptide and Troponin T Levels.

Nozomi Niitsu, M.D., Mika Khori, M.D., Miyuki Hayama, Masaaki Higashihara, M.D., Jun-ichi Tamaru, M.D.
Journal: Blood
Blood (2004) 104 (11): 4608.
https://doi.org/10.1182/blood.V104.11.4608.4608
Published: 2004
Journal Articles

Serum nm23-H1 protein as a prognostic factor in aggressive non-Hodgkin lymphoma

Clinical Trials & Observations
Nozomi Niitsu, Junko Okabe-Kado, Masataka Okamoto, Toshiyuki Takagi, Takashi Yoshida, Sadao Aoki, Masami Hirano, Yoshio Honma
Journal: Blood
Blood (2001) 97 (5): 1202–1210.
https://doi.org/10.1182/blood.V97.5.1202
Published: 2001