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Kazuyuki Shimada
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Journal Articles

Randomized Phase III Study of Watchful Waiting Vs. Rituximab As First-Line Treatment in Patients with Advanced Stage Low Tumor Burden Follicular Lymphoma: JCOG1411/Flora Study

Noriko Fukuhara, Dai Maruyama, Kenichi Ishizawa, Yusuke Sano, Ryunosuke Machida, Shinichi Makita, Wataru Munakata, Satoshi Ichikawa, Keiko Aizawa, Kana Miyazaki, Yoshihiro Kameoka, Shinya Rai, Yu Yagi, Naoki Takahashi, Toshiki Mushino, Takeharu Kato, Yuri Miyazawa, Toko Saito, Kazuyuki Shimada, Junya Kuroda, Hideki Uryu, Yuko Mishima, Nobuyuki Takayama, Yasuhiro Suzuki, Toshiki Uchida, Nobuhiko Nakamura, Takayuki Tabayashi, Yosuke Minami, Nobuaki Dobashi, Kunihiro Tsukasaki, Hirokazu Nagai
Journal: Blood
Blood (2024) 144 (Supplement 1): 338.
https://doi.org/10.1182/blood-2024-199868
Published: 2024
Journal Articles

Whole-Genome Analysis Revealed the Genetic Landscape of Intravascular Large B-Cell Lymphoma

Takuto Mori, Kazuyuki Shimada, Kaito Mimura, Nobuyuki Kakiuchi, Hirona Maeda, Akifumi Takaori-Kondo, Seishi Ogawa, Akihiro Tomita, Kenichi Yoshida
Journal: Blood
Blood (2024) 144 (Supplement 1): 2983.
https://doi.org/10.1182/blood-2024-204466
Published: 2024
Journal Articles

Development and Efficacy of a Novel Bromodomain and Extraterminal Domain Degrader K-256 in MYC/BCL2-Related Lymphoma

Kastuya Furukawa, Kazuyuki Shimada, Masahiro Esaki, Kentaro Tanaka, Keisuke Yamamoto, Kiyotoshi Mori, Hitoshi Kiyoi
Journal: Blood
Blood (2023) 142 (Supplement 1): 5008.
https://doi.org/10.1182/blood-2023-179334
Published: 2023
Journal Articles

Impact of Progression-Free Survival at 24 Months on Subsequent Survival in Patients with Diffuse Large B-Cell Lymphoma Treated with R-CHOP Therapy: A Supplementary Analysis of JCOG0601

Ayumi Fujimoto, Wataru Munakata, Gakuto Ogawa, Tomotaka Suzuki, Kazuyuki Shimada, Tsutomu Kobayashi, Ken Ohmachi, Tomohiro Kinoshita, Kiyoshi Ando, Dai Maruyama, Hirokazu Nagai
Journal: Blood
Blood (2023) 142 (Supplement 1): 4499.
https://doi.org/10.1182/blood-2023-173433
Published: 2023
Journal Articles

The Prognostic Impact of Relative Dose Intensity of Vincristine in R-CHOP for Untreated Patients with Diffuse Large B-Cell Lymphoma: A Supplementary Analysis of JCOG0601

Takahiro Nakashima, Tomotaka Suzuki, Gakuto Ogawa, Kazuyuki Shimada, Tsutomu Kobayashi, Dai Maruyama, Wataru Munakata, Ken Ohmachi, Tomohiro Kinoshita, Kiyoshi Ando, Hirokazu Nagai
Journal: Blood
Blood (2023) 142 (Supplement 1): 1741.
https://doi.org/10.1182/blood-2023-174354
Published: 2023
Journal Articles

Efficacy and Safety of Zanubrutinib in Japanese Patients with Mature B-Cell Malignancies

Takayuki Ishikawa, Masahiro Takeuchi, Kazuyuki Shimada, Kohmei Kubo, Takeshi Kondo, Katsuya Fujimoto, Tomoaki Fujisaki, Koji Nagafuji, Rika Sakai, Shingo Kurahashi, Tatsuro Jo, Kazutaka Sunami, Senji Kasahara, Tomonori Nakazato, Haiyi Guo, William Novotny, Chris Tankersley, Motohisa Takai, Hui Yao, Jinhua Zhong, Hongjie Zhu, Koji Izutsu
Journal: Blood
Blood (2022) 140 (Supplement 1): 3663–3665.
https://doi.org/10.1182/blood-2022-168696
Published: 2022
Journal Articles

Copy Number Alterations of Chromosome 9p24.1 in Elderly Patients with Advanced-Stage Classic Hodgkin Lymphoma Who Received ABVD: An Ancillary Analysis of Multi-Center Retrospective Study in Japan (HORIZON study)

Shinichi Makita, Shigeru Kusumoto, Jun-Ichi Tamaru, Hiroya Hashimoto, Akiko Miyagi Maeshima, Toshiki Uchida, Hideki Tsujimura, Eiichi Ohtsuka, Nobuyuki Takayama, Kayoko Murayama, Naoki Takahashi, Masahiro Yoshida, Hiroaki Morimoto, Yasuhiro Suzuki, Kazuyuki Shimada, Masanori Makita, Shuichi Ota, Hiroshi Gomyo, Hiroyuki Takahashi, Ritsuro Suzuki, Hiroo Katsuya, Hiro Tatetsu, Shuji Momose, Takahisa Yamashita, Kumiko Ohsawa, Naoko Asano, Dai Maruyama, Motoko Yamaguchi, Hirokazu Nagai
Journal: Blood
Blood (2022) 140 (Supplement 1): 11890–11892.
https://doi.org/10.1182/blood-2022-164977
Published: 2022
Journal Articles

Final Analysis of JCOG0203 for Advanced-Stage Indolent B-Cell Lymphoma 15 Years after the End of Enrollment: Pooled Analysis of Arms a and B for Follicular Lymphoma

Takashi Watanabe, Kensei Tobinai, Ｍasashi Wakabayashi, Dai Maruyama, Kazuhito Yamamoto, Nobuko Kubota, Kazuyuki Shimada, Kohsuke Asagoe, Motoko Yamaguchi, Kiyoshi Ando, Michinori Ogura, Junya Kuroda, Youko Suehiro, Yoshihiro Matsuno, Kunihiro Tsukasaki, Hirokazu Nagai
Journal: Blood
Blood (2022) 140 (Supplement 1): 3615–3617.
https://doi.org/10.1182/blood-2022-159967
Published: 2022
Journal Articles

Clinical Outcomes of Elderly Patients with Advanced-Stage Classic Hodgkin Lymphoma Who Received an ABVD Regimen: A Multi-Center Retrospective Study in Japan (HORIZON study)

Shinichi Makita, Shigeru Kusumoto, Akiko Miyagi Maeshima, Hiroya Hashimoto, Hideki Tsujimura, Toshiki Uchida, Hiroaki Inoue, Eiichi Ohtsuka, Mitsutoshi Kurosawa, Nobuyuki Takayama, Eiju Negoro, Yasuhiro Suzuki, Junya Kuroda, Kayoko Murayama, Naoki Takahashi, Kazuyuki Shimada, Masataka Okamoto, Masanori Makita, Hiromi Iwasaki, Masahiro Yoshida, Naoko Asano, Jun-ichi Tamaru, Dai Maruyama, Motoko Yamaguchi, Hirokazu Nagai
Journal: Blood
Blood (2021) 138 (Supplement 1): 2451.
https://doi.org/10.1182/blood-2021-146340
Published: 2021
Journal Articles

Frequent genetic alterations in immune checkpoint–related genes in intravascular large B-cell lymphoma

Kazuyuki Shimada, Kenichi Yoshida, Yasuhiro Suzuki, Chisako Iriyama, Yoshikage Inoue, Masashi Sanada, Keisuke Kataoka, Masaaki Yuge, Yusuke Takagi, Shigeru Kusumoto, Yasufumi Masaki, Takahiko Ito, Yuichiro Inagaki, Akinao Okamoto, Yachiyo Kuwatsuka, Masahiro Nakatochi, Satoko Shimada, Hiroaki Miyoshi, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Yusuke Shiozawa, Yasuhito Nannya, Asako Okabe, Kei Kohno, Yoshiko Atsuta, Koichi Ohshima, Shigeo Nakamura, Seishi Ogawa, Akihiro Tomita, Hitoshi Kiyoi
Journal: Blood
Blood (2021) 137 (11): 1491–1502.
https://doi.org/10.1182/blood.2020007245
Published: 2021
Includes: Supplemental data
Journal Articles

Favorable Outcomes of Newly Diagnosed Intravascular Large B-Cell Lymphoma Patients Treated with R-CHOP Combined with High-Dose Methotrexate Plus Intrathecal Chemotherapy: Results from a Multicenter Phase 2 Trial (PRIMEUR-IVL)

Kazuyuki Shimada, MD, Motoko Yamaguchi, MD PhD, Yoshiko Atsuta, MD PhD, Kosei Matsue, MD PhD, Keijiro Sato, MD, Shigeru Kusumoto, MD PhD, Hirokazu Nagai, MD PhD, Jun Takizawa, MD PhD, Noriko Fukuhara, MD PhD, Koji Nagafuji, MD PhD, Kana Miyazaki, MD PhD, Eiichi Ohtsuka, MD, Masataka Okamoto, MD PhD, Yasumasa Sugita, MD PhD, Toshiki Uchida, MD PhD, Satoshi Kayukawa, MD, Atsushi Wake, MD PhD, Daisuke Ennishi, MD PhD, Yukio Kondo, MD, Tohru Izumi, MD, Yoshihiro Kin, MD, Kunihiro Tsukasaki, MD PhD, Daigo Hashimoto, Masaaki Yuge, MD PhD, Atsumi Yanagisawa, Yachiyo Kuwatsuka, MD PhD, Satoko Shimada, MD, Yasufumi Masaki, MD PhD, Nozomi Niitsu, MD PhD, Hitoshi Kiyoi, MD PhD, Ritsuro Suzuki, MD PhD, Takashi Tokunaga, MD PhD, Shigeo Nakamura, MD, Tomohiro Kinoshita, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 350.
https://doi.org/10.1182/blood-2019-126798
Published: 2019
Journal Articles

Exosomes Derived from Cancer Associated Fibroblasts Elicit Survival and Drug Resistance of Primary Lymphoma Cells

Shunsuke Kunou, Kazuyuki Shimada, MD PhD, Tomoya Hikita, PhD, Tomohiro Aoki, MD PhD, Akihiko Sakamoto, PhD, Fumihiko Hayakawa, MD, PhD, Chitose Oneyama, PhD, Hitoshi Kiyoi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4128.
https://doi.org/10.1182/blood-2018-99-111863
Published: 2018
Journal Articles

Biology and management of primary effusion lymphoma

Kazuyuki Shimada, Fumihiko Hayakawa, Hitoshi Kiyoi
Journal: Blood
Blood (2018) 132 (18): 1879–1888.
https://doi.org/10.1182/blood-2018-03-791426
Published: 2018
Journal Articles

Randomized Phase II Study of R-CHOP-14 Versus R-CHOP-14 Followed By Chaser As Induction Therapy for High-Dose Chemotherapy (HDT), LEED, and Autologous Stem-Cell Transplantation (ASCT) in Poor-Risk Diffuse Large B-Cell Lymphoma (DLBCL): Japan Clinical Oncology Group (JCOG) Study (JCOG0908)

Yoshitoyo Kagami, MD, Kazuhito Yamamoto, MDPhD, Taro Shibata, MSc, Kensei Tobinai, MD PhD, Yoshitaka Imaizumi, MD PhD, Toshiki Uchida, MD PhD, Kazuyuki Shimada, MD, Koichiro Minauchi, MD, Noriko Fukuhara, MD PhD, Hirofumi Kobayashi, MD PhD, Nobuhiko Yamauchi, MD, Hideki Tsujimura, MD PhD, Akira Hangaishi, MD, Ryo Tominaga, MD, Youko Suehiro, MD, Shinichiro Yoshida, MD PhD, Yoshiko Inoue, MD, Sachiko Suzuki, MD, Michihide Tokuhira, MD, Hirokazu Nagai, MD PhD, Shigeru Kusumoto, MD, Junya Kuroda, MD PhD, Yoshihiro Yakushijin, MD PhD, Yasushi Takamatsu, MD PhD, Yasushi Kubota, MD PhD, Kisato Nosaka, MD, Satoko Morishima, MD PhD, Shigeo Nakamura, MD PhD, Dai Maruyama, MD PhD, Tomomitsu Hotta, MD, Yasuo Morishima, MD PhD, Kunihiro Tsukasaki, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4127.
https://doi.org/10.1182/blood.V130.Suppl_1.4127.4127
Published: 2017
Journal Articles

A Novel Prognostic Model for Primary Gastric Diffuse Large B-Cell Lymphoma in the Rituximab Era, Integrating EBV Harboring on Tumor Cells

Eri Ishikawa, MD, Tsutomu Tanaka, Kazuyuki Shimada, MD, Hidemi Goto, Shigeo Nakamura, MD PhD, Seiichi Kato
Journal: Blood
Blood (2017) 130 (Supplement 1): 2836.
https://doi.org/10.1182/blood.V130.Suppl_1.2836.2836
Published: 2017
Journal Articles

Detection of Recurrent Genetic Mutations in Intravascular Large B-Cell Lymphoma By Comprehensive Genetic Analyses Using Peripheral Blood Circulating Cell-Free DNA

Akihiro Tomita, MDPhD, Kazuyuki Shimada, MD, Kenichi Yoshida, MD PhD, Yasuhiro Suzuki, MD PhD, Chisako Iriyama, MD PhD, Masashi Sanada, MD PhD, Masaaki Yuge, MD PhD, Yusuke Takagi, MD PhD, Shigeru Kusumoto, MD, Yasufumi Masaki, MD PhD, Takahiko Ito, MD PhD, Yuichiro Inagaki, MD PhD, Akinao Okamoto, MD PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, B.A., Hiroko Tanaka, B.A., Satoru Miyano, PhD, Seishi Ogawa, MD PhD, Hitoshi Kiyoi, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1452.
https://doi.org/10.1182/blood.V130.Suppl_1.1452.1452
Published: 2017
Journal Articles

Emetine Elicits Apoptosis of Intractable B-Cell Lymphoma Cells with MYC Rearrangement through Inhibition of Glycolytic Metabolism

Tomohiro Aoki, MD, Kazuyuki Shimada, MD PhD, Akihiko Sakamoto, PhD, Keiki Sugimoto, PhD, Takanobu Morishita, MD, Yuki Kojima, MD, Satoko Shimada, MD PhD, Seiichi Kato, MD PhD, Chisako Iriyama, MD PhD, Shunsuke Kuno, MD, Yasuhiko Harada, MD, Shigeo Nakamura, MD PhD, Akihiro Tomita, MD PhD, Fumihiko Hayakawa, MD PhD, Hitoshi Kiyoi, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3019.
https://doi.org/10.1182/blood.V128.22.3019.3019
Published: 2016
Journal Articles

Utilization of Peripheral Blood Cell-Free DNA in Myelodysplastic Syndromes: Clinical and Molecular Characteristics and Utilization for Genetic Analyses Using Conventional and Next-Generation Strategies

Akihiro Tomita, MD PhD, Yasuhiro Suzuki, MD, Fumika Nakamura, Chisako Iriyama, MD PhD, Mizuho Shirahata-Adachi, MD, Kazuyuki Shimada, MD PhD, Akimi Akashi, Yuichi Ishikawa, MDPhD, Norio Kaneda, PhD, Hitoshi Kiyoi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4102.
https://doi.org/10.1182/blood.V126.23.4102.4102
Published: 2015
Journal Articles

Effects of Daily Aspirin on Cancer Incidence and Mortality in the Japanese

Kenji Yokoyama, MD PhD, Naoki Ishizuka, PhD, Naomi Uemura, MD PhD, Yuji Mizokami, MD PhD, Hideyuki Hiraishi, MD PhD, Tamio Teramoto, MD PhD, Kazuyuki Shimada, MD PhD, Yasuo Ikeda, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2322.
https://doi.org/10.1182/blood.V126.23.2322.2322
Published: 2015
Journal Articles

Development and Analysis of Novel Intravascular Large B-Cell Lymphoma NOD/Shi- Scid IL2Rγ null Mouse Xenograft Model

Kazuyuki Shimada, MD PhD, Satoko Shimada, MD PhD, Keiki Sugimoto, Fumihiko Hayakawa, MD PhD, Miyuki Katayama, MD PhD, Akihiro Hirakawa, PhD, Yusuke Takagi, MD, Shigeo Nakamura, MD PhD, Masao Seto, MD PhD, Tomoki Naoe, MDPhD, Akihiro Tomita, MD PhD, Hitoshi Kiyoi, MD PhD
Journal: Blood
Blood (2014) 124 (21): 497.
https://doi.org/10.1182/blood.V124.21.497.497
Published: 2014