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Journal Articles

YM155 Induces Apoptosis through Proteasome-Dependent Degradation of MCL-1 in Primary Effusion Lymphoma

Yuki Kojima, MD, Fumihiko Hayakawa, MD PhD, Takanobu Morishita, MD, Keiki Sugimoto, PhD, Mizuho Iwase, Hideyuki Yamamoto, MD, Daiki Hirano, MD, Naoto Imoto, MD, Seiji Okada, MD, PhD, Hitoshi Kiyoi, MD PhD

Blood (2016) 128 (22): 3013.

https://doi.org/10.1182/blood.V128.22.3013.3013

Published: 2016

Journal Articles

Emetine Elicits Apoptosis of Intractable B-Cell Lymphoma Cells with MYC Rearrangement through Inhibition of Glycolytic Metabolism

Tomohiro Aoki, MD, Kazuyuki Shimada, MD PhD, Akihiko Sakamoto, PhD, Keiki Sugimoto, PhD, Takanobu Morishita, MD, Yuki Kojima, MD, Satoko Shimada, MD PhD, Seiichi Kato, MD PhD, Chisako Iriyama, MD PhD, Shunsuke Kuno, MD, Yasuhiko Harada, MD, Shigeo Nakamura, MD PhD, Akihiro Tomita, MD PhD, Fumihiko Hayakawa, MD PhD, Hitoshi Kiyoi, MD PhD

Blood (2016) 128 (22): 3019.

https://doi.org/10.1182/blood.V128.22.3019.3019

Published: 2016

Journal Articles

A Photosensitizer Verteporfin Has Light-Independent Anti-Leukemic Activity for Ph-Positive Acute Lymphoblastic Leukemia and Synergistically Works with Dasatinib in Vivo

Takanobu Morishita, MD, Fumihiko Hayakawa, MD PhD, Keiki Sugimoto, PhD, Daiki Hirano, MD, Yuki Kojima, MD, Naoto Imoto, MD, Yuichiro Inagaki, MD, Tomoki Naoe, MDPhD, Hitoshi Kiyoi, MD PhD

Blood (2015) 126 (23): 1331.

https://doi.org/10.1182/blood.V126.23.1331.1331

Published: 2015

Journal Articles

PAX5-PML Induces Pro B Acute Lymphoblastic Leukemia in Mice

Naoto Imoto, MD, Shingo Kurahashi, MD PhD, Fumihiko Hayakawa, MD PhD, Takahiko Yasuda, MD PhD, Keiki Sugimoto, Yuki Kojima, MD, Takanobu Morishita, MD, Yuichiro Inagaki, MD, Shinobu Tsuzuki, MD PhD, Tomoki Naoe, MDPhD, Hitoshi Kiyoi, MD PhD

Blood (2014) 124 (21): 887.

https://doi.org/10.1182/blood.V124.21.887.887

Published: 2014

Journal Articles

Development and Analysis of Novel Intravascular Large B-Cell Lymphoma NOD/Shi- Scid IL2Rγ null Mouse Xenograft Model

Kazuyuki Shimada, MD PhD, Satoko Shimada, MD PhD, Keiki Sugimoto, Fumihiko Hayakawa, MD PhD, Miyuki Katayama, MD PhD, Akihiro Hirakawa, PhD, Yusuke Takagi, MD, Shigeo Nakamura, MD PhD, Masao Seto, MD PhD, Tomoki Naoe, MDPhD, Akihiro Tomita, MD PhD, Hitoshi Kiyoi, MD PhD

Blood (2014) 124 (21): 497.

https://doi.org/10.1182/blood.V124.21.497.497

Published: 2014

Journal Articles

Rituximab Sensitivity to De Novo DLBCL Cells Showing the Specific Phenotype of CD20 Protein Immunohistochemistry-Positive / Flow Cytometory-Negative: Analyses of Its Clinical Significances and the Molecular Mechanisms.

Akihiro Tomita, MD, Ph.D., Takashi Tokunaga, MD, Tatsuya Hirose, Keiki Sugimoto, Kazuyuki Shimada, MD, Ph.D., Norio Kaneda, MD, Ph.D., Hitoshi Kiyoi, MD, PhD, Naoko Asano, MD, Ph.D., Shigeo Nakamura, M.D., Ph.D., Tomohiro Kinoshita, M.D., Ph.D., Tomoki Naoe, MD, PhD

Blood (2012) 120 (21): 2682.

https://doi.org/10.1182/blood.V120.21.2682.2682

Published: 2012

Journal Articles

Drug Development Targeting Microenvironment for Malignant Lymphoma

Keiki Sugimoto, Fumihiko Hayakawa, MD, PhD, Takahiko Yasuda, MD, Ph.D., Tomoki Naoe, MD, PhD

Blood (2012) 120 (21): 1661.

https://doi.org/10.1182/blood.V120.21.1661.1661

Published: 2012

Journal Articles

CD20 Protein Immunohistochemistry-Positive/Flow Cytometry-Negative Diffuse Large B-Cell Lymphoma—Analyses of the Molecular Mechanisms and Rituximab Effectiveness

Takashi Tokunaga, MD, Akihiro Tomita, MD, PhD, Junji Hiraga, MD, PhD, Takumi Sugimoto, MD, PhD, Kazuyuki Shimada, MD, PhD, Keiki Sugimoto, Tomohiro Kinoshita, MD, PhD, Tomoki Naoe, MD, PhD.

Blood (2011) 118 (21): 2659.

https://doi.org/10.1182/blood.V118.21.2659.2659

Published: 2011

Journal Articles

A Novel STAT3 Inhibitor OPB-31121 Induces Tumor-Specific Growth Inhibition in a Wide Range of Hematopoietic Malignancies without Growth Suppression of Normal Hematopoietic Cells

Fumihiko Hayakawa, MD, PhD, Keiki Sugimoto, Shingo Kurahashi, MD, PhD, Takumi Sumida, DVM, Tomoki Naoe, MD, PhD

Blood (2011) 118 (21): 577.

https://doi.org/10.1182/blood.V118.21.577.577

Published: 2011

Journal Articles

A Novel Direct STAT3 Inhibitor OPB-31121 Induces Tumor-Specific Growth Inhibition In a Wide Range of Hematopoietic Malignancies and Effectively Suppresses the Chemotherapy Resistant Quiescent Cells In Vivo

Fumihiko Hayakawa, MD, PhD, Keiki Sugimoto, Shingo Kurahashi, MD, Hironori Matsuyama, Yasuo Harada, Norikazu Hashimoto, Naoto Ohi, Takeshi Kodama, Takumi Sumida, Tomohiro Kinoshita, MD, PhD, Tomoki Naoe, MD, PhD

Blood (2010) 116 (21): 3277.

https://doi.org/10.1182/blood.V116.21.3277.3277

Published: 2010

NARROW

YM155 Induces Apoptosis through Proteasome-Dependent Degradation of MCL-1 in Primary Effusion Lymphoma

Emetine Elicits Apoptosis of Intractable B-Cell Lymphoma Cells with MYC Rearrangement through Inhibition of Glycolytic Metabolism

A Photosensitizer Verteporfin Has Light-Independent Anti-Leukemic Activity for Ph-Positive Acute Lymphoblastic Leukemia and Synergistically Works with Dasatinib in Vivo

PAX5-PML Induces Pro B Acute Lymphoblastic Leukemia in Mice

Development and Analysis of Novel Intravascular Large B-Cell Lymphoma NOD/Shi- Scid IL2Rγ null Mouse Xenograft Model

Rituximab Sensitivity to De Novo DLBCL Cells Showing the Specific Phenotype of CD20 Protein Immunohistochemistry-Positive / Flow Cytometory-Negative: Analyses of Its Clinical Significances and the Molecular Mechanisms.

Drug Development Targeting Microenvironment for Malignant Lymphoma

CD20 Protein Immunohistochemistry-Positive/Flow Cytometry-Negative Diffuse Large B-Cell Lymphoma—Analyses of the Molecular Mechanisms and Rituximab Effectiveness

A Novel STAT3 Inhibitor OPB-31121 Induces Tumor-Specific Growth Inhibition in a Wide Range of Hematopoietic Malignancies without Growth Suppression of Normal Hematopoietic Cells

A Novel Direct STAT3 Inhibitor OPB-31121 Induces Tumor-Specific Growth Inhibition In a Wide Range of Hematopoietic Malignancies and Effectively Suppresses the Chemotherapy Resistant Quiescent Cells In Vivo

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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