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Journal Articles

Disentangling the Effects of HLA DRB115:01 and DQB106:02 to Establish the True HLA Risk Allele for Inhibitor Development in the Treatment of Hemophilia A

Vincent P. Diego, PhD, Bernadette W. Luu, B.S., M.T. (CLS), Alexis Garza, B.S., Marco Hofmann, M.S., Marcio A. Almeida, PhD, Jerry S. Powell, MD, Long V. Dinh, PhD, Raja Rajalingam, PhD, Juan M Peralta, M.S., Satish Kumar, PhD, Eli Fine, PhD, Joanne E. Curran, PhD, Miguel A. Escobar, MD, Sarah Williams-Blangero, PhD, Eugene Maraskovsky, PhD, John Blangero, PhD, Tom E. Howard, MD, PhD

Blood (2020) 136 (Supplement 1): 1–2.

https://doi.org/10.1182/blood-2020-142716

Published: 2020

Journal Articles

N-Linked Glycans on Therapeutic Factor VIII (FVIII) Proteins Attenuate Immunogenicity Potential: Evidence from Independent HLA-Class-II/FVIII (HLAcII/FVIII) Peptidomes

Vincent P. Diego, PhD, Bernadette W. Luu, B.S., M.T. (CLS), Hari Movva, B.S., Marco Hofmann, M.S., Marcio A. Almeida, PhD, Long V. Dinh, PhD, Jerry S. Powell, MD, Raja Rajalingam, PhD, Juan M Peralta, M.S., Henry Mead, M.B.A., M.P.H., Satish Kumar, PhD, Joanne E. Curran, PhD, Miguel A. Escobar, MD, Sarah Williams-Blangero, PhD, Eugene Maraskovsky, PhD, John Blangero, PhD, Tom E. Howard, MD, PhD

Blood (2020) 136 (Supplement 1): 29–30.

https://doi.org/10.1182/blood-2020-142493

Published: 2020

Journal Articles

The Role of Class II Human Leukocyte Antigens (cII-HLAs) in Determining the Immunogenic Potential of Therapeutic Factor VIII Proteins in Hemophilia Patients: The "Gate Keeper" Hypothesis

Vincent P. Diego, PhD, Bernadette W. Luu, BS, MT/CLS, Marco Hofmann, MS, Marcio A. Almeida, PhD, Jose Antonio G. Hernandez, PhD, Juan Peralta, MS, Joanne Curran, PhD, Jerry S. Powell, MD, Raja Rajalingam, PhD, Long V. Dinh, PhD, Sarah Williams-Blangero, PhD, Miguel A Escobar, MD, Eugene Maraskovsky, PhD, John Blangero, PhD, Tom E. Howard

Blood (2018) 132 (Supplement 1): 5022.

https://doi.org/10.1182/blood-2018-99-115537

Published: 2018

Journal Articles

Characterization of the HLA-Class-II (HLAcII)/Therapeutic Factor VIII (FVIII)-Derived Peptidome By FVIII Domain and HLAcII Isomer

Marcio Almeida, PhD, Vincent P. Diego, PhD, Bernadette W. Luu, B.S., Marco Hofmann, M.S., Jose Antonio G. Hernandez, PhD, Juan Peralta, Joanne Curran, Miguel A Escobar, MD, Rajalingam Raja, PhD, LV Dinh, Jerry S. Powell, MD, Sarah Williams-Blangero, John Blangero, Eugene Maraskovsky, Tom Howard

Blood (2017) 130 (Supplement 1): 2352.

https://doi.org/10.1182/blood.V130.Suppl_1.2352.2352

Published: 2017

Journal Articles

Profiling and Comparing the Immunogenicity of a Novel Single-Chain FVIII Molecule (rVIII-SingleChain) for the Treatment of Hemophilia a

Eugene Maraskovsky, PhD, Anne Verhagen, PhD, Huy Huynh, BS, Adriana Baz Morelli, PhD, Stefan Schmidbauer, BS, Sabine Zollner, PhD, Jerry S. Powell, Katie St Ledger, Alex Veldman, MD, Marco Hofmann, MS

Blood (2016) 128 (22): 4960.

https://doi.org/10.1182/blood.V128.22.4960.4960

Published: 2016

Journal Articles

A Novel Biomarker for Inhibitor Risk Prediction-the HLA-II Bound and Unbound Components of FVIII Derived Peptides-Reveals a Protective Influence for N-Linked Glycosylation

Kevin R. Viel, PhD, Marco Hofmann, MD PhD, Sabine Zollner, Bernadette W. Luu, Rajalingam Raja, PhD, Jerry Sherman Powell, MD, Eugene Maraskovsky, MD, PhD, Tom E. Howard, MD PhD

Blood (2015) 126 (23): 2292.

https://doi.org/10.1182/blood.V126.23.2292.2292

Published: 2015

Journal Articles

Processing and cross-presentation of individual HLA-A, -B, or -C epitopes from NY-ESO-1 or an HLA-A epitope for Melan-A differ according to the mode of antigen delivery

Neil C. Robson, Tristan McAlpine, Ashley J. Knights, Max Schnurr, Amanda Shin, Weisan Chen, Eugene Maraskovsky, Jonathan Cebon

Blood (2010) 116 (2): 218–225.

https://doi.org/10.1182/blood-2009-10-249458

Published: 2010

Includes: Supplemental data

Journal Articles

Activin-A attenuates several human natural killer cell functions

Neil C. Robson, Heng Wei, Tristan McAlpine, Naomi Kirkpatrick, Jonathan Cebon, Eugene Maraskovsky

Blood (2009) 113 (14): 3218–3225.

https://doi.org/10.1182/blood-2008-07-166926

Published: 2009

Includes: Supplemental data

Journal Articles

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

Blood (2008) 112 (8): 3264–3273.

https://doi.org/10.1182/blood-2008-05-155176

Published: 2008

Includes: Supplemental data

Journal Articles

P2Y receptor signaling regulates phenotype and IFN-α secretion of human plasmacytoid dendritic cells

Amanda Shin, Tracey Toy, Simon Rothenfusser, Neil Robson, Julia Vorac, Marc Dauer, Moritz Stuplich, Stefan Endres, Jonathan Cebon, Eugene Maraskovsky, Max Schnurr

Blood (2008) 111 (6): 3062–3069.

https://doi.org/10.1182/blood-2007-02-071910

Published: 2008

Journal Articles

Activin-A: a novel dendritic cell–derived cytokine that potently attenuates CD40 ligand–specific cytokine and chemokine production

Neil C. Robson, David J. Phillips, Tristan McAlpine, Amanda Shin, Suzanne Svobodova, Tracey Toy, Vinochani Pillay, Naomi Kirkpatrick, Damien Zanker, Kathy Wilson, Imke Helling, Heng Wei, Weisan Chen, Jonathan Cebon, Eugene Maraskovsky

Blood (2008) 111 (5): 2733–2743.

https://doi.org/10.1182/blood-2007-03-080994

Published: 2008

Includes: Supplemental data

Journal Articles

GSK-3 mediates differentiation and activation of proinflammatory dendritic cells

Elena Rodionova, Michael Conzelmann, Eugene Maraskovsky, Michael Hess, Michael Kirsch, Thomas Giese, Anthony D. Ho, Margot Zöller, Peter Dreger, Thomas Luft

Blood (2006) 109 (4): 1584–1592.

https://doi.org/10.1182/blood-2006-06-028951

Published: 2006

Includes: Supplemental data

Journal Articles

Adaptive functional differentiation of dendritic cells: integrating the network of extra- and intracellular signals

Thomas Luft, Elena Rodionova, Eugene Maraskovsky, Michael Kirsch, Michael Hess, Christian Buchholtz, Martin Goerner, Max Schnurr, Radek Skoda, Anthony D. Ho

Blood (2006) 107 (12): 4763–4769.

https://doi.org/10.1182/blood-2005-04-1501

Published: 2006

Includes: Supplemental data

Journal Articles

IDO production, adaptive immunity, and CTL killing

Thomas Luft, Eugene Maraskovsky, Max Schnurr

Blood (2005) 106 (7): 2228–2229.

https://doi.org/10.1182/blood-2005-07-2877

Published: 2005

Journal Articles

Tumor antigen processing and presentation depend critically on dendritic cell type and the mode of antigen delivery

Max Schnurr, Qiyuan Chen, Amanda Shin, Weisan Chen, Tracey Toy, Corinna Jenderek, Simon Green, Lena Miloradovic, Debbie Drane, Ian D. Davis, Jose Villadangos, Ken Shortman, Eugene Maraskovsky, Jonathan Cebon

Blood (2005) 105 (6): 2465–2472.

https://doi.org/10.1182/blood-2004-08-3105

Published: 2005

Journal Articles

Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway

Max Schnurr, Tracey Toy, Amanda Shin, Moritz Wagner, Jonathan Cebon, Eugene Maraskovsky

Blood (2005) 105 (4): 1582–1589.

https://doi.org/10.1182/blood-2004-05-1718

Published: 2005

Journal Articles

Tuning the volume of the immune response: strength and persistence of stimulation determine migration and cytokine secretion of dendritic cells

Thomas Luft, Eugene Maraskovsky, Max Schnurr, Katja Knebel, Michael Kirsch, Martin Görner, Radek Skoda, Anthony D. Ho, Peter Nawroth, Angelika Bierhaus

Blood (2004) 104 (4): 1066–1074.

https://doi.org/10.1182/blood-2003-12-4146

Published: 2004

Journal Articles

Role of adenosine receptors in regulating chemotaxis and cytokine production of plasmacytoid dendritic cells

Max Schnurr, Tracey Toy, Amanda Shin, Gunther Hartmann, Simon Rothenfusser, Julia Soellner, Ian D. Davis, Jonathan Cebon, Eugene Maraskovsky

Blood (2004) 103 (4): 1391–1397.

https://doi.org/10.1182/blood-2003-06-1959

Published: 2004

Journal Articles

Functional comparison of DCs generated in vivo with Flt3 ligand or in vitro from blood monocytes: differential regulation of function by specific classes of physiologic stimuli

Michael Jefford, Max Schnurr, Tracey Toy, Kelly-Anne Masterman, Amanda Shin, Tina Beecroft, Tsin Yee Tai, Ken Shortman, Mark Shackleton, Ian D. Davis, Phil Parente, Thomas Luft, Weisan Chen, Jonathan Cebon, Eugene Maraskovsky

Blood (2003) 102 (5): 1753–1763.

https://doi.org/10.1182/blood-2002-12-3854

Published: 2003

Journal Articles

ATP gradients inhibit the migratory capacity of specific human dendritic cell types: implications for P2Y 11 receptor signaling

Max Schnurr, Tracey Toy, Patrizia Stoitzner, Paul Cameron, Amanda Shin, Tina Beecroft, Ian D. Davis, Jonathan Cebon, Eugene Maraskovsky

Blood (2003) 102 (2): 613–620.

https://doi.org/10.1182/blood-2002-12-3745

Published: 2003

NARROW

Disentangling the Effects of HLA DRB115:01 and DQB106:02 to Establish the True HLA Risk Allele for Inhibitor Development in the Treatment of Hemophilia A

N-Linked Glycans on Therapeutic Factor VIII (FVIII) Proteins Attenuate Immunogenicity Potential: Evidence from Independent HLA-Class-II/FVIII (HLAcII/FVIII) Peptidomes

The Role of Class II Human Leukocyte Antigens (cII-HLAs) in Determining the Immunogenic Potential of Therapeutic Factor VIII Proteins in Hemophilia Patients: The "Gate Keeper" Hypothesis

Characterization of the HLA-Class-II (HLAcII)/Therapeutic Factor VIII (FVIII)-Derived Peptidome By FVIII Domain and HLAcII Isomer

Profiling and Comparing the Immunogenicity of a Novel Single-Chain FVIII Molecule (rVIII-SingleChain) for the Treatment of Hemophilia a

A Novel Biomarker for Inhibitor Risk Prediction-the HLA-II Bound and Unbound Components of FVIII Derived Peptides-Reveals a Protective Influence for N-Linked Glycosylation

Processing and cross-presentation of individual HLA-A, -B, or -C epitopes from NY-ESO-1 or an HLA-A epitope for Melan-A differ according to the mode of antigen delivery

Activin-A attenuates several human natural killer cell functions

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

P2Y receptor signaling regulates phenotype and IFN-α secretion of human plasmacytoid dendritic cells

Activin-A: a novel dendritic cell–derived cytokine that potently attenuates CD40 ligand–specific cytokine and chemokine production

GSK-3 mediates differentiation and activation of proinflammatory dendritic cells

Adaptive functional differentiation of dendritic cells: integrating the network of extra- and intracellular signals

IDO production, adaptive immunity, and CTL killing

Tumor antigen processing and presentation depend critically on dendritic cell type and the mode of antigen delivery

Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway

Tuning the volume of the immune response: strength and persistence of stimulation determine migration and cytokine secretion of dendritic cells

Role of adenosine receptors in regulating chemotaxis and cytokine production of plasmacytoid dendritic cells

Functional comparison of DCs generated in vivo with Flt3 ligand or in vitro from blood monocytes: differential regulation of function by specific classes of physiologic stimuli

ATP gradients inhibit the migratory capacity of specific human dendritic cell types: implications for P2Y 11 receptor signaling

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American Society of Hematology

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ASH Publications

American Society of Hematology

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