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Volume 105, Issue 1

January 1 2005

In this Issue

INSIDE BLOOD
BLOOD WORK
REVIEW ARTICLES
ERRATA
REVIEW IN TRANSLATIONAL HEMATOLOGY
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
RED CELLS
TRANSPLANTATION
CORRESPONDENCE

INSIDE BLOOD

HEMOSTASIS

Gla glances at proteins

Tilman M. Hackeng

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CLINICAL OBSERVATIONS

CLL therapy: progress at last!

Emili Montserrat

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HEMOSTASIS

Clotting hits the wall

James H. Morrissey

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HEMOSTASIS

New insights in heparin-induced thrombocytopenia

Michael H. Rosove

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HEMOSTASIS

A platelet cloak for tumor cells

Hartmut Weiler

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NEOPLASIA

Modeling CML in mice: SpeCiaL expression is the key

Richard A. Van Etten

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TRANSPLANTATION

Noninvasive monitoring of cellular movements: the utility of MRI and magnetically labeled cells

James P. Basilion

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IMMUNOBIOLOGY

Long live T cells

Laurence J. N. Cooper

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HEMATOPOIESIS

A Fli in the ointment

Ramesh A. Shivdasani

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BLOOD WORK

Case of meningococcal sepsis and purpura fulminans

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REVIEW ARTICLES

The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation

James L. Riley,Carl H. June

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ERRATA

Erratum for vol. 104, p. 3422

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REVIEW IN TRANSLATIONAL HEMATOLOGY

After chronic myelogenous leukemia: tyrosine kinase inhibitors in other hematologic malignancies
Clinical Trials & Observations

Martha Wadleigh,Daniel J. DeAngelo,James D. Griffin,Richard M. Stone

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CHEMOKINES

The role of CCL21 in recruitment of T-precursor cells to fetal thymi

Cunlan Liu,Tomoo Ueno,Sachiyo Kuse,Fumi Saito,Takeshi Nitta,Luca Piali,Hideki Nakano,Terutaka Kakiuchi,Martin Lipp,Georg A. Hollander,Yousuke Takahama

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Supplemental data

Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient

Marcin Wysoczynski,Ryan Reca,Janina Ratajczak,Magda Kucia,Neeta Shirvaikar,Marek Honczarenko,Michael Mills,Jens Wanzeck,Anna Janowska-Wieczorek,Mariusz Z. Ratajczak

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CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011
Clinical Trials & Observations

John C. Byrd,Kanti Rai,Bercedis L. Peterson,Frederick R. Appelbaum,Vicki A. Morrison,Jonathan E. Kolitz,Lois Shepherd,John D. Hines,Charles A. Schiffer,Richard A. Larson

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Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412
Clinical Trials & Observations

Richard M. Stone,Daniel J. DeAngelo,Virginia Klimek,Ilene Galinsky,Eli Estey,Stephen D. Nimer,Wilson Grandin,David Lebwohl,Yanfeng Wang,Pamela Cohen,Edward A. Fox,Donna Neuberg,Jennifer Clark,D. Gary Gilliland,James D. Griffin

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Unusual late presentation of X-linked chronic granulomatous disease in an adult female with a somatic mosaic for a novel mutation in CYBB
Clinical Trials & Observations

Baruch Wolach,Yitshak Scharf,Ronit Gavrieli,Martin de Boer,Dirk Roos

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Risk of head and neck squamous cell cancer and death in patients with Fanconi anemia who did and did not receive transplants
Clinical Trials & Observations

Philip S. Rosenberg,Gerard Socié,Blanche P. Alter,Eliane Gluckman

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Splenic lymphoma with villous lymphocytes, associated with type II cryoglobulinemia and HCV infection: a new entity?
Clinical Trials & Observations Brief Report

David Saadoun,Felipe Suarez,François Lefrere,Françoise Valensi,Xavier Mariette,Achille Aouba,Caroline Besson,Bruno Varet,Xavier Troussard,Patrice Cacoub,Oliver Hermine

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HEMATOPOIESIS

Enforced expression of an Flt3 internal tandem duplication in human CD34⁺ cells confers properties of self-renewal and enhanced erythropoiesis

Ki Young Chung,Giovanni Morrone,Jan Jacob Schuringa,Bryan Wong,David C. Dorn,Malcolm A. S. Moore

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Different steroids co-regulate long-term expansion versus terminal differentiation in primary human erythroid progenitors

Cornelia Leberbauer,Florence Boulmé,Gertrud Unfried,Johannes Huber,Hartmut Beug,Ernst W. Müllner

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Supplemental data

Dysregulation of granulocyte, erythrocyte, and NK cell lineages in Fli-1 gene–targeted mice

Masahiro Masuya,Omar Moussa,Takanori Abe,Takao Deguchi,Tsukasa Higuchi,Yasuhiro Ebihara,Demetri D. Spyropoulos,Dennis K. Watson,Makio Ogawa

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Role of the renin-angiotensin system in primitive erythropoiesis in the chick embryo

Katia Savary,Annie Michaud,Judith Favier,Etienne Larger,Pierre Corvol,Jean-Marie Gasc

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Modulation of hematopoietic and endothelial cell differentiation from mouse embryonic stem cells by different culture conditions
Brief Report

Wen Jie Zhang,Changwon Park,Elizabeth Arentson,Kyunghee Choi

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Supplemental data

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Nongenomic effects of 17β-estradiol in human platelets: potentiation of thrombin-induced aggregation through estrogen receptor β and Src kinase

Laura Moro,Stefania Reineri,Daniela Piranda,Daniela Pietrapiana,Paolo Lova,Alessandra Bertoni,Andrea Graziani,Paola Defilippi,Ilaria Canobbio,Mauro Torti,Fabiola Sinigaglia

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The γ-carboxyglutamic acid domain of anticoagulant protein S is involved in activated protein C cofactor activity, independently of phospholipid binding

François Saller,Bruno O. Villoutreix,Aymeric Amelot,Tahar Kaabache,Bernard F. Le Bonniec,Martine Aiach,Sophie Gandrille,Delphine Borgel

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Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia

Lubica Rauova,Mortimer Poncz,Steven E. McKenzie,Michael P. Reilly,Gowthami Arepally,John W. Weisel,Chandrasekaran Nagaswami,Douglas B. Cines,Bruce S. Sachais

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Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin
Clinical Trials & Observations

Pierre Savi,Beng H. Chong,Andreas Greinacher,Yves Gruel,John G. Kelton,Theodore E. Warkentin,Petra Eichler,Dick Meuleman,Maurice Petitou,Jean-Pascal Herault,Roger Cariou,Jean-Marc Herbert

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Re-establishment of VWF-dependent Weibel-Palade bodies in VWD endothelial cells

Sandra L. Haberichter,Elizabeth P. Merricks,Scot A. Fahs,Pamela A. Christopherson,Timothy C. Nichols,Robert R. Montgomery

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Acute cholesterol depletion impairs functional expression of tissue factor in fibroblasts: modulation of tissue factor activity by membrane cholesterol

Samir K. Mandal,Alexei Iakhiaev,Usha R. Pendurthi,L. Vijaya Mohan Rao

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Rod mutations associated with MYH9-related disorders disrupt nonmuscle myosin-IIA assembly

Josef D. Franke,Fan Dong,Wayne L. Rickoll,Michael J. Kelley,Daniel P. Kiehart

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LDL-receptor–related protein regulates β2-integrin–mediated leukocyte adhesion

Patricia P. E. M. Spijkers,Paula da Costa Martins,Erik Westein,Carl G. Gahmberg,Jaap J. Zwaginga,Peter J. Lenting

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Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell–mediated elimination of tumor cells

Joseph S. Palumbo,Kathryn E. Talmage,Jessica V. Massari,Christine M. La Jeunesse,Matthew J. Flick,Keith W. Kombrinck,Markéta Jirousková,Jay L. Degen

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Platelet activation induces metalloproteinase-dependent GP VI cleavage to down-regulate platelet reactivity to collagen

Gillian Stephens,Yibing Yan,Martine Jandrot-Perrus,Jean-Luc Villeval,Kenneth J. Clemetson,David R. Phillips

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Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall

Sharlene M. Day,Jennifer L. Reeve,Brian Pedersen,Diana M Farris,Daniel D. Myers,Michael Im,Thomas W. Wakefield,Nigel Mackman,William P. Fay

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Increased circulating hematopoietic and endothelial progenitor cells in the early phase of acute myocardial infarction

Margherita Massa,Vittorio Rosti,Maurizio Ferrario,Rita Campanelli,Isabella Ramajoli,Roberta Rosso,Gaetano M. De Ferrari,Marco Ferlini,Lucio Goffredo,Alessandra Bertoletti,Catherine Klersy,Alessandro Pecci,Remigio Moratti,Luigi Tavazzi

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Vascular endothelial growth factor regulation of Weibel-Palade–body exocytosis

Kenji Matsushita,Munekazu Yamakuchi,Craig N. Morrell,Michitaka Ozaki,Brian O'Rourke,Kaikobad Irani,Charles J. Lowenstein

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Platelet-associated CD154 in immune thrombocytopenic purpura
Brief Report

Anne Solanilla,Jean-Max Pasquet,Jean-François Viallard,Cécile Contin,Christophe Grosset,Julie Déchanet-Merville,Maryse Dupouy,Marc Landry,Francis Belloc,Paquita Nurden,Patrick Blanco,Jean-François Moreau,Jean-Luc Pellegrin,Alan T. Nurden,Jean Ripoche

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IMMUNOBIOLOGY

Impaired CD40L signaling is a cause of defective IL-12 and TNF-α production in Sézary syndrome: circumvention by hexameric soluble CD40L

Lars E. French,Bertrand Huard,Maria Wysocka,Ryan Shane,Emmanuel Contassot,Jean-François Arrighi,Vincent Piguet,Silvio Calderara,Alain H. Rook

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Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl)

Shan Zeng,Zhiheng Xu,Stan Lipkowitz,Jack B. Longley

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NKG2D receptor–mediated NK cell function is regulated by inhibitory Ly49 receptors

Jeyarani Regunathan,Yuhong Chen,Demin Wang,Subramaniam Malarkannan

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Supplemental data

Transition of late-stage effector T cells to CD27⁺ CD28⁺ tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy

Daniel J. Powell, Jr,Mark E. Dudley,Paul F. Robbins,Steven A. Rosenberg

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HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells

Ennio Carbone,Paola Neri,Maria Mesuraca,Mariateresa T. Fulciniti,Takemi Otsuki,Daniela Pende,Veronika Groh,Thomas Spies,Giuditta Pollio,David Cosman,Lucio Catalano,Pierfrancesco Tassone,Bruno Rotoli,Salvatore Venuta

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Tumor suppressor function of Bruton tyrosine kinase is independent of its catalytic activity

Sabine Middendorp,A. J. Esther Zijlstra,Rogier Kersseboom,Gemma M. Dingjan,Hassan Jumaa,Rudolf W. Hendriks

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Mature myeloid dendritic cell subsets have distinct roles for activation and viability of circulating human natural killer cells

Christian Münz,Tao Dao,Guido Ferlazzo,Maria A. de Cos,Kiera Goodman,James W. Young

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Modulation of cord blood CD8⁺ T-cell effector differentiation by TGF-β1 and 4-1BB costimulation

Young-June Kim,Teresa M. Stringfield,Yan Chen,Hal E. Broxmeyer

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Stabilization of IFN-γ mRNA by MAPK p38 in IL-12– and IL-18–stimulated human NK cells

Athanasios Mavropoulos,Gareth Sully,Andrew P. Cope,Andrew R. Clark

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NEOPLASIA

FCGR3A and FCGR2A polymorphisms may not correlate with response to alemtuzumab in chronic lymphocytic leukemia
Clinical Trials & Observations

Thomas S. Lin,Ian W. Flinn,Rama Modali,Teresa A. Lehman,Jennifer Webb,Sharon Waymer,Mollie E. Moran,Margaret S. Lucas,Sherif S. Farag,John C. Byrd

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Physical and functional link of the leukemia-associated factors AML1 and PML

Lan Anh Nguyen,Pier Paolo Pandolfi,Yukiko Aikawa,Yusuke Tagata,Misao Ohki,Issay Kitabayashi

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Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment
Clinical Trials & Observations

Annuska M. Glas,Marie José Kersten,Leonie J. M. J. Delahaye,Anke T. Witteveen,Robby E. Kibbelaar,Arno Velds,Lodewyk F. A. Wessels,Peter Joosten,Ron M. Kerkhoven,René Bernards,Johan H. J. M. van Krieken,Philip M. Kluin,Laura J. van't Veer,Daphne de Jong

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Supplemental data

The phosphodiesterase PDE4B limits cAMP-associated PI3K/AKT–dependent apoptosis in diffuse large B-cell lymphoma

Peter G. Smith,Fengfei Wang,Kathryn N. Wilkinson,Kerry J. Savage,Ulf Klein,Donna S. Neuberg,Gideon Bollag,Margaret A. Shipp,Ricardo C. T. Aguiar

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Supplemental data

Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition in some plasma cell tumors
Clinical Trials & Observations

Thomas Rasmussen,Michael Kuehl,Marianne Lodahl,Hans E. Johnsen,Inger Marie S. Dahl

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Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis

Steffen Koschmieder,Berthold Göttgens,Pu Zhang,Junko Iwasaki-Arai,Koichi Akashi,Jeffery L. Kutok,Tajhal Dayaram,Kristin Geary,Anthony R. Green,Daniel G. Tenen,Claudia S. Huettner

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Identification of a novel activating mutation (Y842C) within the activation loop of FLT3 in patients with acute myeloid leukemia (AML)

Thomas Kindler,Frank Breitenbuecher,Stefan Kasper,Eli Estey,Francis Giles,Eric Feldman,Gerhard Ehninger,Gary Schiller,Virginia Klimek,Stephen D. Nimer,Alois Gratwohl,Chuna Ram Choudhary,Constan Mueller-Tidow,Hubert Serve,Harald Gschaidmeier,Pamela S. Cohen,Christoph Huber,Thomas Fischer

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Retinoids and myelomonocytic growth factors cooperatively activate RARΑ and induce human myeloid leukemia cell differentiation via MAP kinase pathways

Annegret Glasow,Natalia Prodromou,Ke Xu,Marieke von Lindern,Arthur Zelent

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Patupilone (epothilone B) inhibits growth and survival of multiple myeloma cells in vitro and in vivo

Boris Lin,Laurence Catley,Richard LeBlanc,Constantine Mitsiades,Renate Burger,Yu-Tzu Tai,Klaus Podar,Markus Wartmann,Dharminder Chauhan,James D. Griffin,Kenneth C. Anderson

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p53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation
Brief Report

Hong Chang,Connie Qi,Qi-Long Yi,Donna Reece,A. Keith Stewart

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RED CELLS

Distribution of dehydration rates generated by maximal Gardos-channel activation in normal and sickle red blood cells

Virgilio L. Lew,Teresa Tiffert,Zipora Etzion,Deisy Perdomo,Nuala Daw,Lynn Macdonald,Robert M. Bookchin

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Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria

An-Sheng Zhang,Alex D. Sheftel,Prem Ponka

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Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis

Hiroshi Kawabata,Robert E. Fleming,Dorina Gui,Seo Y. Moon,Takayuki Saitoh,James O'Kelly,Yutaka Umehara,Yuji Wano,Jonathan W. Said,H. Phillip Koeffler

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Abnormal regulation of Mg²⁺ transport via Na/Mg exchanger in sickle erythrocytes

Alicia Rivera,Ana Ferreira,Danielle Bertoni,José R. Romero,Carlo Brugnara

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A sustained and pancellular reversal of gamma-globin gene silencing in adult human erythroid precursor cells

Natarajan V. Bhanu,Tiffany A. Trice,Y. Terry Lee,Nicole M. Gantt,Patricia Oneal,Joseph D. Schwartz,Pierre Noel,Jeffery L. Miller

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Disruption of Plasmodium berghei merozoite surface protein 7 gene modulates parasite growth in vivo
Brief Report

Rita Tewari,Solabomi A. Ogun,Ruwani S. Gunaratne,Andrea Crisanti,Anthony A. Holder

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TRANSPLANTATION

Results of the MRC pilot study show autografting for younger patients with chronic lymphocytic leukemia is safe and achieves a high percentage of molecular responses
Clinical Trials & Observations

Donald W. Milligan,Savio Fernandes,Ranjit Dasgupta,Faith E. Davies,Estella Matutes,Christopher D. Fegan,Christopher McConkey,J. Anthony Child,David Cunningham,Gareth J. Morgan,Daniel Catovsky,for the National Cancer Research Institute (NCRI) Haematological Studies Group

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Hematopoietic stem cell transplantation for de novo acute megakaryocytic leukemia in first complete remission: a retrospective study of the European Group for Blood and Marrow Transplantation (EBMT)
Clinical Trials & Observations

Laurent Garderet,Myriam Labopin,Norbert-Claude Gorin,Emmanuelle Polge,André Baruchel,Giovanna Meloni,Juan Ortega,Jaak Vossen,Donald Bunjes,Guy Leverger,Didier Blaise,Augustin Ferrant,Mats Brune,Eric Dore,Helmut Gadner,Felix Zintl,Isaac Yaniv,Giorgio Dini,Francesco Frassoni

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Hematopoietic stem cell transplantation (HSCT) in children with juvenile myelomonocytic leukemia (JMML): results of the EWOG-MDS/EBMT trial
Clinical Trials & Observations

Franco Locatelli,Peter Nöllke,Marco Zecca,Elisabeth Korthof,Edoardo Lanino,Christina Peters,Andrea Pession,Hartmut Kabisch,Cornelio Uderzo,Carmen S. Bonfim,Peter Bader,Dagmar Dilloo,Jan Stary,Alexandra Fischer,Tom Révész,Monika Führer,Henrik Hasle,Monika Trebo,Marry M. van den Heuvel-Eibrink,Susanna Fenu,Brigitte Strahm,Giovanna Giorgiani,Mario Regazzi Bonora,Ulrich Duffner,Charlotte M. Niemeyer,on behalf of the European Working Group on Childhood MDS (EWOG-MDS) and the European Blood and Marrow Transplantation (EBMT) Group

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Noninvasive MR imaging of magnetically labeled stem cells to directly identify neovasculature in a glioma model

Stasia A. Anderson,John Glod,Ali S. Arbab,Martha Noel,Parwana Ashari,Howard A. Fine,Joseph A. Frank

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Complete remission of alopecia universalis after allogeneic hematopoietic stem cell transplantation
Clinical Trials & Observations Brief Report

Bettina Seifert,Jakob R. Passweg,Dominik Heim,Alicia Rovó,Sandrine Meyer-Monard,Stanislaus Buechner,Andre Tichelli,Alois Gratwohl

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Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration
Brief Report

Maria Gendelman,Nadine Halligan,Richard Komorowski,Brent Logan,William J. Murphy,Bruce R. Blazar,Kirkwood A. Pritchard, Jr,William R. Drobyski

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CORRESPONDENCE

Homozygosity for a novel nonsense mutation (G66X) of the HJV gene causes severe juvenile hemochromatosis with fatal cardiomyopathy

András Jánosi,Hajnalka Andrikovics,Katalin Vas,András Bors,Márta Hubay,Zoltán Sápi,Attila Tordai

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Issue Archive

Table of Contents

INSIDE BLOOD

BLOOD WORK

REVIEW ARTICLES

ERRATA

REVIEW IN TRANSLATIONAL HEMATOLOGY

After chronic myelogenous leukemia: tyrosine kinase inhibitors in other hematologic malignancies Clinical Trials & Observations

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011 Clinical Trials & Observations

Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412 Clinical Trials & Observations

Unusual late presentation of X-linked chronic granulomatous disease in an adult female with a somatic mosaic for a novel mutation in CYBB Clinical Trials & Observations

Risk of head and neck squamous cell cancer and death in patients with Fanconi anemia who did and did not receive transplants Clinical Trials & Observations

Splenic lymphoma with villous lymphocytes, associated with type II cryoglobulinemia and HCV infection: a new entity? Clinical Trials & Observations Brief Report

HEMATOPOIESIS

Modulation of hematopoietic and endothelial cell differentiation from mouse embryonic stem cells by different culture conditions Brief Report

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin Clinical Trials & Observations

Platelet-associated CD154 in immune thrombocytopenic purpura Brief Report

IMMUNOBIOLOGY

NEOPLASIA

FCGR3A and FCGR2A polymorphisms may not correlate with response to alemtuzumab in chronic lymphocytic leukemia Clinical Trials & Observations

Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment Clinical Trials & Observations

Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition in some plasma cell tumors Clinical Trials & Observations

p53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation Brief Report

RED CELLS

Disruption of Plasmodium berghei merozoite surface protein 7 gene modulates parasite growth in vivo Brief Report

TRANSPLANTATION

Results of the MRC pilot study show autografting for younger patients with chronic lymphocytic leukemia is safe and achieves a high percentage of molecular responses Clinical Trials & Observations

Hematopoietic stem cell transplantation for de novo acute megakaryocytic leukemia in first complete remission: a retrospective study of the European Group for Blood and Marrow Transplantation (EBMT) Clinical Trials & Observations

Hematopoietic stem cell transplantation (HSCT) in children with juvenile myelomonocytic leukemia (JMML): results of the EWOG-MDS/EBMT trial Clinical Trials & Observations

Complete remission of alopecia universalis after allogeneic hematopoietic stem cell transplantation Clinical Trials & Observations Brief Report

Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration Brief Report

CORRESPONDENCE

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ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

After chronic myelogenous leukemia: tyrosine kinase inhibitors in other hematologic malignancies
Clinical Trials & Observations

Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011
Clinical Trials & Observations

Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412
Clinical Trials & Observations

Unusual late presentation of X-linked chronic granulomatous disease in an adult female with a somatic mosaic for a novel mutation in CYBB
Clinical Trials & Observations

Risk of head and neck squamous cell cancer and death in patients with Fanconi anemia who did and did not receive transplants
Clinical Trials & Observations

Splenic lymphoma with villous lymphocytes, associated with type II cryoglobulinemia and HCV infection: a new entity?
Clinical Trials & Observations Brief Report

Modulation of hematopoietic and endothelial cell differentiation from mouse embryonic stem cells by different culture conditions
Brief Report

Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin
Clinical Trials & Observations

Platelet-associated CD154 in immune thrombocytopenic purpura
Brief Report

FCGR3A and FCGR2A polymorphisms may not correlate with response to alemtuzumab in chronic lymphocytic leukemia
Clinical Trials & Observations

Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment
Clinical Trials & Observations

Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition in some plasma cell tumors
Clinical Trials & Observations

p53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation
Brief Report

Disruption of Plasmodium berghei merozoite surface protein 7 gene modulates parasite growth in vivo
Brief Report

Results of the MRC pilot study show autografting for younger patients with chronic lymphocytic leukemia is safe and achieves a high percentage of molecular responses
Clinical Trials & Observations

Hematopoietic stem cell transplantation for de novo acute megakaryocytic leukemia in first complete remission: a retrospective study of the European Group for Blood and Marrow Transplantation (EBMT)
Clinical Trials & Observations

Hematopoietic stem cell transplantation (HSCT) in children with juvenile myelomonocytic leukemia (JMML): results of the EWOG-MDS/EBMT trial
Clinical Trials & Observations

Complete remission of alopecia universalis after allogeneic hematopoietic stem cell transplantation
Clinical Trials & Observations Brief Report

Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration
Brief Report