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Pamela S. Cohen
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Journal Articles

Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain

Clinical Trials & Observations
Florian Heidel, Fian K. Solem, Frank Breitenbuecher, Daniel B. Lipka, Stefan Kasper, M. H. Thiede, Christian Brandts, Hubert Serve, Johannes Roesel, Francis Giles, Eric Feldman, Gerhard Ehninger, Gary J. Schiller, Stephen Nimer, Richard M. Stone, Yanfeng Wang, Thomas Kindler, Pamela S. Cohen, Christoph Huber, Thomas Fischer
Journal: Blood
Blood (2006) 107 (1): 293–300.
https://doi.org/10.1182/blood-2005-06-2469
Published: 2006
Journal Articles

Phase IB Study of PKC412, an Oral FLT3 Kinase Inhibitor, in Sequential and Simultaneous Combinations with Daunorubicin and Cytarabine (DA) Induction and High-Dose Cytarabine Consolidation in Newly Diagnosed Patients with AML.

Richard M. Stone, Thomas Fischer, Ronald Paquette, Gary Schiller, Charles A. Schiffer, Gerhard Ehninger, Jorge Cortes, Hagop Kantarjian, Daniel A. DeAngelo, Richard Yu, Lei Zhang, Pamela S. Cohen, Yanfeng Wang, Penny Phillips, Francis Giles
Journal: Blood
Blood (2005) 106 (11): 404.
https://doi.org/10.1182/blood.V106.11.404.404
Published: 2005
Journal Articles

Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation

Clinical Trials & Observations Brief Report
Jason Gotlib, Caroline Berubé, Joseph D. Growney, Ching-Cheng Chen, Tracy I. George, Christopher Williams, Tomohiro Kajiguchi, Jia Ruan, Stan L. Lilleberg, Jeffrey A. Durocher, Jack H. Lichy, Yanfeng Wang, Pamela S. Cohen, Daniel A. Arber, Michael C. Heinrich, Len Neckers, Stephen J. Galli, D. Gary Gilliland, Steven E. Coutré
Journal: Blood
Blood (2005) 106 (8): 2865–2870.
https://doi.org/10.1182/blood-2005-04-1568
Published: 2005
Journal Articles

Identification of a novel activating mutation (Y842C) within the activation loop of FLT3 in patients with acute myeloid leukemia (AML)

Thomas Kindler, Frank Breitenbuecher, Stefan Kasper, Eli Estey, Francis Giles, Eric Feldman, Gerhard Ehninger, Gary Schiller, Virginia Klimek, Stephen D. Nimer, Alois Gratwohl, Chuna Ram Choudhary, Constan Mueller-Tidow, Hubert Serve, Harald Gschaidmeier, Pamela S. Cohen, Christoph Huber, Thomas Fischer
Journal: Blood
Blood (2005) 105 (1): 335–340.
https://doi.org/10.1182/blood-2004-02-0660
Published: 2005