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Journal Articles

Coexpression of the T-cell receptor constant α domain triggers tumor reactivity of single-chain TCR-transduced human T cells

Ralf-Holger Voss, Simone Thomas, Christina Pfirschke, Beate Hauptrock, Sebastian Klobuch, Jürgen Kuball, Margarete Grabowski, Renate Engel, Philippe Guillaume, Pedro Romero, Christoph Huber, Philipp Beckhove, Matthias Theobald

Blood (2010) 115 (25): 5154–5163.

https://doi.org/10.1182/blood-2009-11-254078

Published: 2010

Includes: Supplemental data

Journal Articles

Long-Term Persistence of Functionally Altered GPI-Anchor Negative T-Cell Subsets After Alemtuzumab-Based T-Cell Depleted Hematopoietic Stem Cell Transplantation.

Eva M Wagner, Aline N Lay, Timo Schmitt, Julia Hemmerling, Diana Wolff, Christoph Huber, Wolfgang Herr, Ralf G Meyer

Blood (2009) 114 (22): 2438.

https://doi.org/10.1182/blood.V114.22.2438.2438

Published: 2009

Journal Articles

A novel molecular mechanism of primary resistance to FLT3-kinase inhibitors in AML

Frank Breitenbuecher, Boyka Markova, Stefan Kasper, Birgit Carius, Torsten Stauder, Frank D. Böhmer, Kristina Masson, Lars Rönnstrand, Christoph Huber, Thomas Kindler, Thomas Fischer

Blood (2009) 113 (17): 4063–4073.

https://doi.org/10.1182/blood-2007-11-126664

Published: 2009

Includes: Supplemental data

Journal Articles

Identification of a novel type of ITD mutations located in nonjuxtamembrane domains of the FLT3 tyrosine kinase receptor

Frank Breitenbuecher, Susanne Schnittger, Rebekka Grundler, Boyka Markova, Birgit Carius, Alexandra Brecht, Justus Duyster, Torsten Haferlach, Christoph Huber, Thomas Fischer

Blood (2009) 113 (17): 4074–4077.

https://doi.org/10.1182/blood-2007-11-125476

Published: 2009

Journal Articles

The CD38-Positive and CD38-Negative Subsets of CD34(high)-Positive Primary Acute Myeloid Leukemia Blasts Differ Considerably in the Expression of Immune Recognition Molecules

Eva Distler, Anna Jürchott, Abdo Konur, Astrid Schneider, Eva M. Wagner, Christoph Huber, Ralf G. Meyer, Wolfgang Herr

Blood (2008) 112 (11): 2936.

https://doi.org/10.1182/blood.V112.11.2936.2936

Published: 2008

Journal Articles

Reconstitution of CD52-Negative CD4 T Cells after Alemtuzumab-Based T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

Eva M Wagner, MD, Aline N Lay, Sina Wenzel, Timo Schmitt, Julia Hemmerling, Abdo Konur, PhD, Klaus Bender, PhD, Christoph Huber, MD, Wolfgang Herr, MD, Ralf G Meyer, MD

Blood (2008) 112 (11): 1182.

https://doi.org/10.1182/blood.V112.11.1182.1182

Published: 2008

Journal Articles

CD8-Depleted Donor Lymphocyte Infusions Convert Mixed into Complete Donor T-Cell Chimerism after T-Cell Depleted Allogeneic Stem Cell Transplantation.

Ralf G Meyer, MD, Eva M Wagner, MD, Timo Schmitt, Klaus Bender, PhD, Udo F Hartwig, PhD, Christoph Huber, MD, Karin Kolbe, MD, Wolfgang Herr, MD

Blood (2008) 112 (11): 2160.

https://doi.org/10.1182/blood.V112.11.2160.2160

Published: 2008

Journal Articles

An immune escape screen reveals Cdc42 as regulator of cancer susceptibility to lymphocyte-mediated tumor suppression

Celio A. Marques, Patricia S. Hähnel, Catherine Wölfel, Sonja Thaler, Christoph Huber, Matthias Theobald, Martin Schuler

Blood (2008) 111 (3): 1413–1419.

https://doi.org/10.1182/blood-2007-05-089458

Published: 2008

Includes: Supplemental data

Journal Articles

Graft-Versus-Host Disease or Infection: Rapid Detection of HLA Mismatch-Reactive T Cells Ex Vivo Can Facilitate Diagnosis and Guide Therapy after Allogeneic Transplantation.

Eva Distler, Simone Thomas, Elke Schuerer, Cedrik Britten, Martin Schuler, Christoph Huber, Karin Kolbe, Thomas Woelfel, Ralf Meyer, Wolfgang Herr

Blood (2007) 110 (11): 4993.

https://doi.org/10.1182/blood.V110.11.4993.4993

Published: 2007

Journal Articles

Chimerism Analysis of Langerhans Cells Early after T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation.

Timo Schmitt, Kerstin Schneiker, Abdo Konur, PhD, Ali Hadian, MD, Klaus Bender, PhD, Esther von Stebut, MD, Karin Kolbe, MD, Christoph Huber, MD, Wolfgang Herr, MD, Ralf G. Meyer, MD

Blood (2007) 110 (11): 3249.

https://doi.org/10.1182/blood.V110.11.3249.3249

Published: 2007

Journal Articles

The JAK2 Kinase Inhibitor LS104 Induces Growth-Arrest and Apoptosis in JAK2V617F Positive Cells.

Daniel B. Lipka, MD, Linda S. Hoffmann, MSc, Florian Heidel, MD, Boyka Markova, PhD, Stefan Kasper, MD, Frank Breitenbuecher, PhD, Thomas Kindler, MD, Ross Levine, MD, Joseph Elliot, PhD, Christoph Huber, MD, Thomas Fischer, MD

Blood (2007) 110 (11): 3544.

https://doi.org/10.1182/blood.V110.11.3544.3544

Published: 2007

Journal Articles

Rapid Detection and Isolation of Viable Virus-Reactive CD4 + and CD8 + T Cells Based on Activation-Induced CD137 Expression.

Thomas C. Wehler, Michael Karg, Abdo Konur, Marion Nonn, Ralf G. Meyer, Christoph Huber, Udo F. Hartwig, Wolfgang Herr

Blood (2007) 110 (11): 1972.

https://doi.org/10.1182/blood.V110.11.1972.1972

Published: 2007

Journal Articles

3,4-Diarylmaleimides Effectively Inhibit Proliferation of FLT3-ITD-Positive Leukemic Cells, Induce Apoptosis and Show Additive Effects in Combination with Chemotherapeutic Drugs.

Florian H. Heidel, MD, Daniel B. Lipka, MD, Fian K. Mirea, Boyka Markova, PhD, Christian Peifer, PhD, Jan-Peter Kramp, PhD, Stanislav Plutizki, Christoph Huber, MD, Gerd Dannhardt, PhD, Thomas Fischer, MD

Blood (2007) 110 (11): 1605.

https://doi.org/10.1182/blood.V110.11.1605.1605

Published: 2007

Journal Articles

Drug treatment is superior to allografting as first-line therapy in chronic myeloid leukemia

Blood (2007) 109 (11): 4686–4692.

https://doi.org/10.1182/blood-2006-11-055186

Published: 2007

Includes: Supplemental data

Journal Articles

Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells

Silke Holtkamp, Sebastian Kreiter, Abderraouf Selmi, Petra Simon, Michael Koslowski, Christoph Huber, Özlem Türeci, Ugur Sahin

Blood (2006) 108 (13): 4009–4017.

https://doi.org/10.1182/blood-2006-04-015024

Published: 2006

Journal Articles

A neoepitope generated by an FLT3 internal tandem duplication ( FLT3-ITD ) is recognized by leukemia-reactive autologous CD8 + T cells

Claudine Graf, Florian Heidel, Stefan Tenzer, Markus P. Radsak, Fian K. Solem, Cedrik M. Britten, Christoph Huber, Thomas Fischer, Thomas Wölfel

Blood (2006) 109 (7): 2985–2988.

https://doi.org/10.1182/blood-2006-07-032839

Published: 2006

Includes: Supplemental data

Journal Articles

Bis(1 H -indol-2yl)methanones Are Effective Inhibitors of Mutated FLT3 Tyrosine Kinase, Overcome Resistance to PKC412A In Vitro and Show Synergy with Chemotherapy.

Florian Heidel, Fian K. Mirea, Frank Breitenbucher, Stefan Dove, Christoph Huber, Frank D. Bohmer, Thomas Fischer

Blood (2006) 108 (11): 1369.

https://doi.org/10.1182/blood.V108.11.1369.1369

Published: 2006

Journal Articles

Rapid Expansion of Acute Myeloid Leukemia-Reactive Cytotoxic T Cells from CD8+CD62L+ Blood Lymphocytes of HLA-Matched Healthy Donors In Vitro

Eva Distler, Catherine Woelfel, PhD, Sylvia Pesth, Nina Kraus, Thomas C. Wehler, MD, Ralf G. Meyer, MD, Marion Nonn, PhD, Christoph Huber, MD, Thomas Woelfel, MD, Wolfgang Herr, MD

Blood (2006) 108 (11): 3238.

https://doi.org/10.1182/blood.V108.11.3238.3238

Published: 2006

Journal Articles

Playing the Game Together: Coexpression of a Single Chain T Cell Receptor and a T Cell Receptor Constant-Alpha Domain Triggers Tumor Reactivity.

Simone Thomas, MD, Ralf H. Voss, PhD, Ratna Intan, Renate Engel, Juergen Kuball, MD, Christoph Huber, MD, Matthias Theobald, MD

Blood (2006) 108 (11): 3716.

https://doi.org/10.1182/blood.V108.11.3716.3716

Published: 2006

Journal Articles

Phenotype, Function, and Safety of a p53 TCR Bicistronic GMP-Suitable Retroviral Construct.

Florian Rohrbach, PhD, Gunda Brandenburg, Ph.D., Edite Antunes Ferreira, Vera Wimmenauer, Daniel Hirsch, Thomas Stanislawski, Ph.D., Christoph Huber, M.D., Matthias Theobald, M.D.

Blood (2006) 108 (11): 3695.

https://doi.org/10.1182/blood.V108.11.3695.3695

Published: 2006

NARROW

Coexpression of the T-cell receptor constant α domain triggers tumor reactivity of single-chain TCR-transduced human T cells

Long-Term Persistence of Functionally Altered GPI-Anchor Negative T-Cell Subsets After Alemtuzumab-Based T-Cell Depleted Hematopoietic Stem Cell Transplantation.

A novel molecular mechanism of primary resistance to FLT3-kinase inhibitors in AML

Identification of a novel type of ITD mutations located in nonjuxtamembrane domains of the FLT3 tyrosine kinase receptor

The CD38-Positive and CD38-Negative Subsets of CD34(high)-Positive Primary Acute Myeloid Leukemia Blasts Differ Considerably in the Expression of Immune Recognition Molecules

Reconstitution of CD52-Negative CD4 T Cells after Alemtuzumab-Based T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

CD8-Depleted Donor Lymphocyte Infusions Convert Mixed into Complete Donor T-Cell Chimerism after T-Cell Depleted Allogeneic Stem Cell Transplantation.

An immune escape screen reveals Cdc42 as regulator of cancer susceptibility to lymphocyte-mediated tumor suppression

Graft-Versus-Host Disease or Infection: Rapid Detection of HLA Mismatch-Reactive T Cells Ex Vivo Can Facilitate Diagnosis and Guide Therapy after Allogeneic Transplantation.

Chimerism Analysis of Langerhans Cells Early after T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation.

The JAK2 Kinase Inhibitor LS104 Induces Growth-Arrest and Apoptosis in JAK2V617F Positive Cells.

Rapid Detection and Isolation of Viable Virus-Reactive CD4 + and CD8 + T Cells Based on Activation-Induced CD137 Expression.

3,4-Diarylmaleimides Effectively Inhibit Proliferation of FLT3-ITD-Positive Leukemic Cells, Induce Apoptosis and Show Additive Effects in Combination with Chemotherapeutic Drugs.

Drug treatment is superior to allografting as first-line therapy in chronic myeloid leukemia

Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells

A neoepitope generated by an FLT3 internal tandem duplication ( FLT3-ITD ) is recognized by leukemia-reactive autologous CD8 + T cells

Bis(1 H -indol-2yl)methanones Are Effective Inhibitors of Mutated FLT3 Tyrosine Kinase, Overcome Resistance to PKC412A In Vitro and Show Synergy with Chemotherapy.

Rapid Expansion of Acute Myeloid Leukemia-Reactive Cytotoxic T Cells from CD8+CD62L+ Blood Lymphocytes of HLA-Matched Healthy Donors In Vitro

Playing the Game Together: Coexpression of a Single Chain T Cell Receptor and a T Cell Receptor Constant-Alpha Domain Triggers Tumor Reactivity.

Phenotype, Function, and Safety of a p53 TCR Bicistronic GMP-Suitable Retroviral Construct.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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