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Journal Articles

Signaling through the type 2 cannabinoid receptor regulates the severity of acute and chronic graft-versus-host disease

Cheng Yin Yuan, Vivian Zhou, Garrett Sauber, Todd Stollenwerk, Richard Komorowski, Alicia López, Rosa María Tolón, Julian Romero, Cecilia J. Hillard, William R. Drobyski

Blood (2021) 137 (9): 1241–1255.

https://doi.org/10.1182/blood.2020004871

Published: 2021

Includes: Supplemental data

Journal Articles

Pathogenic Bhlhe40 + GM-CSF + CD4 + T cells promote indirect alloantigen presentation in the GI tract during GVHD

Clint Piper, Vivian Zhou, Richard Komorowski, Aniko Szabo, Benjamin Vincent, Jonathan Serody, Maria-Luisa Alegre, Brian T. Edelson, Reshma Taneja, William R. Drobyski

Blood (2020) 135 (8): 568–581.

https://doi.org/10.1182/blood.2019001696

Published: 2020

Includes: Supplemental data

Journal Articles

Blockade of interleukin-27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing Foxp3 expression

Ludovic Belle, Kimberle Agle, Vivian Zhou, Cheng Yin-Yuan, Richard Komorowski, Daniel Eastwood, Brent Logan, Jie Sun, Nico Ghilardi, Daniel Cua, Calvin B. Williams, Melanie Gaignage, Reece Marillier, Jacques van Snick, William R. Drobyski

Blood (2016) 128 (16): 2068–2082.

https://doi.org/10.1182/blood-2016-02-698241

Published: 2016

Journal Articles

Coordinate Expression of Beta 2 Integrins and the Interleukin 23 Receptor Define a Pathogenic CD4+ T Cell Population That Induces Colonic Inflammation during Graft Versus Host Disease

Kimberle Agle, PhD, Vivian Zhou, PhD, Xiao Chen, MD PhD, Amy Beres, PhD, Richard Komorowski, MD, Carolyn Taylor, PhD, Dipica Haribhai, Calvin Williams, MD PhD, James Verbsky, MDPhD, Wendy Blumenschein, PhD, Svetlana Sadekova, PhD, Eddie Bowman, PhD, Casey Weaver, MD, Daniel Cua, PhD, William R. Drobyski, MD

Blood (2014) 124 (21): 537.

https://doi.org/10.1182/blood.V124.21.537.537

Published: 2014

Journal Articles

A critical role for the retinoic acid signaling pathway in the pathophysiology of gastrointestinal graft-versus-host disease

Xiao Chen, Joseph Dodge, Richard Komorowski, William R. Drobyski

Blood (2013) 121 (19): 3970–3980.

https://doi.org/10.1182/blood-2012-08-445130

Published: 2013

Journal Articles

Emergence of T cells that recognize nonpolymorphic antigens during graft-versus- host disease

Hemalatha Rangarajan, Maryam Yassai, Hariharan Subramanian, Richard Komorowski, Megan Whitaker, Jack Gorski, William R. Drobyski

Blood (2012) 119 (26): 6354–6364.

https://doi.org/10.1182/blood-2012-01-401596

Published: 2012

Includes: Supplemental data

Journal Articles

Emergence of Donor T Cells That Recognize Nonpolymorphic Antigens During Graft Versus Host Disease,

Hemalatha Rangarajan, MD, Maryam Yassai, Xiao Chen, MD, PhD, Richard Komorowski, MD, Jack Gorski, PhD, William R. Drobyski, MD

Blood (2011) 118 (21): 4013.

https://doi.org/10.1182/blood.V118.21.4013.4013

Published: 2011

Journal Articles

Stability of Foxp3 Expression Is a Critical Factor In the Ability of Regulatory T Cells to Mitigate Graft Versus Host Disease

Amy Beres, Richard Komorowski, MD, William R. Drobyski, MD

Blood (2010) 116 (21): 731.

https://doi.org/10.1182/blood.V116.21.731.731

Published: 2010

Journal Articles

Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses

Rupali Das, Richard Komorowski, Martin J. Hessner, Hariharan Subramanian, Claudia S. Huettner, Daniel Cua, William R. Drobyski

Blood (2010) 115 (25): 5249–5258.

https://doi.org/10.1182/blood-2009-11-255422

Published: 2010

Journal Articles

Blockade of IL-23 Signaling Results in Targeted Protection of the Colon and Allows for Separation of Graft Versus Host and Graft Versus Leukemia Effects.

Rupali Das, Ph.D., Richard Komorowski, M.D., Martin Hessner, Ph.D., Hariharan Subramaniam, PhD, Daniel J Cua, PhD, Claudia Huettner, PhD, William R. Drobyski, MD

Blood (2009) 114 (22): 231.

https://doi.org/10.1182/blood.V114.22.231.231

Published: 2009

Journal Articles

Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease

Xiao Chen, Rupali Das, Richard Komorowski, Amy Beres, Martin J. Hessner, Masahiko Mihara, William R. Drobyski

Blood (2009) 114 (4): 891–900.

https://doi.org/10.1182/blood-2009-01-197178

Published: 2009

Journal Articles

Interleukin-23 secretion by donor antigen-presenting cells is critical for organ-specific pathology in graft-versus-host disease

Rupali Das, Xiao Chen, Richard Komorowski, Martin J. Hessner, William R. Drobyski

Blood (2009) 113 (10): 2352–2362.

https://doi.org/10.1182/blood-2008-08-175448

Published: 2009

Includes: Supplemental data

Journal Articles

Blockade of Interleukin 6 Signaling Attenuates Graft Versus Host Disease by Augmenting Regulatory T Cell Reconstitution

Xiao Chen, Ph.D., Rupali Das, Ph.D., Richard Komorowski, M.D., Masahiko Mihara, Ph.D., William Drobyski, M.D.

Blood (2008) 112 (11): 811.

https://doi.org/10.1182/blood.V112.11.811.811

Published: 2008

Journal Articles

Interleukin 23 Secretion by Donor Antigen Presenting Cells Is Critical for Organ-Specific Pathology in Graft Versus Host Disease

Rupali Das, Ph.D., Xiao Chen, Ph.D., Richard Komorowski, M.D., Martin Hessner, Ph.D., William R. Drobyski, MD

Blood (2008) 112 (11): 64.

https://doi.org/10.1182/blood.V112.11.64.64

Published: 2008

Journal Articles

Inhibition of Interleukin 17 Significantly Attenuates the Severity of Autoimmune-Mediated Pathological Damage in Chronic Graft Versus Host Disease.

Xiao Chen, MD, PhD, Jacques Van Snick, Catherine Uyttenhove, Richard Komorowski, MD, William R. Drobyski, MD

Blood (2007) 110 (11): 70.

https://doi.org/10.1182/blood.V110.11.70.70

Published: 2007

Journal Articles

Absence of regulatory T-cell control of T H 1 and T H 17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease

Xiao Chen, Sanja Vodanovic-Jankovic, Bryon Johnson, Melissa Keller, Richard Komorowski, William R. Drobyski

Blood (2007) 110 (10): 3804–3813.

https://doi.org/10.1182/blood-2007-05-091074

Published: 2007

Includes: Supplemental data

Journal Articles

Homeostatic expansion and repertoire regeneration of donor T cells during graft versus host disease is constrained by the host environment

Jack Gorski, Xiao Chen, Mariya Gendelman, Maryam Yassai, Ashley Krueger, Elizabeth Tivol, Brent Logan, Richard Komorowski, Sanja Vodanovic-Jankovic, William R. Drobyski

Blood (2007) 109 (12): 5502–5510.

https://doi.org/10.1182/blood-2006-12-061713

Published: 2007

Journal Articles

NF-κB as a target for the prevention of graft-versus-host disease: comparative efficacy of bortezomib and PS-1145

Sanja Vodanovic-Jankovic, Parameswaran Hari, Paulette Jacobs, Richard Komorowski, William R. Drobyski

Blood (2006) 107 (2): 827–834.

https://doi.org/10.1182/blood-2005-05-1820

Published: 2006

Journal Articles

Targeting NF-Kβ for the Prevention of Graft Versus Host Disease.

William R. Drobyski, MD, Sanja Vodanovic-Jankovic, MD, PhD, Parameswaran Hari, MD, Paulette Jacobs, MS, Richard Komorowski, MD

Blood (2005) 106 (11): 3109.

https://doi.org/10.1182/blood.V106.11.3109.3109

Published: 2005

Journal Articles

Emergent autoimmunity in graft-versus-host disease

Elizabeth Tivol, Richard Komorowski, William R. Drobyski

Blood (2005) 105 (12): 4885–4891.

https://doi.org/10.1182/blood-2004-12-4980

Published: 2005

NARROW

Signaling through the type 2 cannabinoid receptor regulates the severity of acute and chronic graft-versus-host disease

Pathogenic Bhlhe40 + GM-CSF + CD4 + T cells promote indirect alloantigen presentation in the GI tract during GVHD

Blockade of interleukin-27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing Foxp3 expression

Coordinate Expression of Beta 2 Integrins and the Interleukin 23 Receptor Define a Pathogenic CD4+ T Cell Population That Induces Colonic Inflammation during Graft Versus Host Disease

A critical role for the retinoic acid signaling pathway in the pathophysiology of gastrointestinal graft-versus-host disease

Emergence of T cells that recognize nonpolymorphic antigens during graft-versus- host disease

Emergence of Donor T Cells That Recognize Nonpolymorphic Antigens During Graft Versus Host Disease,

Stability of Foxp3 Expression Is a Critical Factor In the Ability of Regulatory T Cells to Mitigate Graft Versus Host Disease

Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses

Blockade of IL-23 Signaling Results in Targeted Protection of the Colon and Allows for Separation of Graft Versus Host and Graft Versus Leukemia Effects.

Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease

Interleukin-23 secretion by donor antigen-presenting cells is critical for organ-specific pathology in graft-versus-host disease

Blockade of Interleukin 6 Signaling Attenuates Graft Versus Host Disease by Augmenting Regulatory T Cell Reconstitution

Interleukin 23 Secretion by Donor Antigen Presenting Cells Is Critical for Organ-Specific Pathology in Graft Versus Host Disease

Inhibition of Interleukin 17 Significantly Attenuates the Severity of Autoimmune-Mediated Pathological Damage in Chronic Graft Versus Host Disease.

Absence of regulatory T-cell control of T H 1 and T H 17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease

Homeostatic expansion and repertoire regeneration of donor T cells during graft versus host disease is constrained by the host environment

NF-κB as a target for the prevention of graft-versus-host disease: comparative efficacy of bortezomib and PS-1145

Targeting NF-Kβ for the Prevention of Graft Versus Host Disease.

Emergent autoimmunity in graft-versus-host disease

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American Society of Hematology

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American Society of Hematology

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