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Journal Articles

Robust expansion of HIV CAR T cells following antigen boosting in ART-suppressed nonhuman primates

Blake J. Rust, Leslie S. Kean, Lucrezia Colonna, Katherine E. Brandenstein, Nikhita H. Poole, Willimark Obenza, Mark R. Enstrom, Colby R. Maldini, Gavin I. Ellis, Christine M. Fennessey, Meei-Li Huang, Brandon F. Keele, Keith R. Jerome, James L. Riley, Hans-Peter Kiem, Christopher W. Peterson

Blood (2020) 136 (15): 1722–1734.

https://doi.org/10.1182/blood.2020006372

Published: 2020

Includes: Supplemental data

Journal Articles

In Vitro Induction of Human Regulatory T-Cells (iTregs) Using Conditions of Low Tryptophan Plus Kynurenines

Keli L. Hippen, PhD, Margaret L. MacMillan, MD, Amanda Lemire, BS, Asim Saha, PhD, Eric Hanse, Colin Lord, Ameeta Kelekar, PhD, Roddy S. O'Connor, PhD, James L. Riley, PhD, Carl H June, MD, Leslie Kean, MD PhD, Jeffrey S. Miller, MD, John E. Wagner, MD, David H. Munn, MD, Bruce R. Blazar, MD

Blood (2016) 128 (22): 1229.

https://doi.org/10.1182/blood.V128.22.1229.1229

Published: 2016

Journal Articles

miR-146b antagomir–treated human Tregs acquire increased GVHD inhibitory potency

Yunjie Lu, Keli L. Hippen, Amanda L. Lemire, Jian Gu, Weizhi Wang, Xuhao Ni, Parvathi Ranganathan, Bruce L. Levine, James L. Riley, Carl H. June, Laurence A. Turka, David H. Munn, Ramiro Garzon, Ling Lu, Bruce R. Blazar

Blood (2016) 128 (10): 1424–1435.

https://doi.org/10.1182/blood-2016-05-714535

Published: 2016

Includes: Supplemental data

Journal Articles

Umbilical cord blood–derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

Claudio G. Brunstein, Jeffrey S. Miller, David H. McKenna, Keli L. Hippen, Todd E. DeFor, Darin Sumstad, Julie Curtsinger, Michael R. Verneris, Margaret L. MacMillan, Bruce L. Levine, James L. Riley, Carl H. June, Chap Le, Daniel J. Weisdorf, Philip B. McGlave, Bruce R. Blazar, John E. Wagner

Blood (2016) 127 (8): 1044–1051.

https://doi.org/10.1182/blood-2015-06-653667

Published: 2016

Includes: Supplemental data

Journal Articles

Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality

Blood (2015) 126 (23): 147.

https://doi.org/10.1182/blood.V126.23.147.147

Published: 2015

Journal Articles

Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease

Bruce R. Blazar, MD, Roddy S. O'Connor, PhD, Michael C. Milone, MD PhD, Michael L. Dustin, PhD, James L. Riley, PhD, Benjamin G. Vincent, MD, Jonathan S. Serody, MD, Ryan P Flynn, PhD, Katelyn Paz, Jing Du, Angela Panoskaltsis-Mortari, PhD, Miller Jeffrey, MD, Rafi Ahmed, PhD, Laurence A. A. Turka, MD, Gordon J. Freeman, PhD, Arlene H. Sharpe, MDPhD, Asim Saha, PhD

Blood (2015) 126 (23): SCI-8.

https://doi.org/10.1182/blood.V126.23.SCI-8.SCI-8

Published: 2015

Journal Articles

Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4 + T cells from HIV-1 infection

Chuka A. Didigu, Craig B. Wilen, Jianbin Wang, Jennifer Duong, Anthony J. Secreto, Gwenn A. Danet-Desnoyers, James L. Riley, Phillip D. Gregory, Carl H. June, Michael C. Holmes, Robert W. Doms

Blood (2014) 123 (1): 61–69.

https://doi.org/10.1182/blood-2013-08-521229

Published: 2014

Includes: Supplemental data

Journal Articles

TCR affinity and specificity requirements for human regulatory T-cell function

Gabriela Plesa, Lingjie Zheng, Andrew Medvec, Caleph B. Wilson, Camila Robles-Oteiza, Nathaniel Liddy, Alan D. Bennett, Jessie Gavarret, Annelise Vuidepot, Yangbing Zhao, Bruce R. Blazar, Bent K. Jakobsen, James L. Riley

Blood (2012) 119 (15): 3420–3430.

https://doi.org/10.1182/blood-2011-09-377051

Published: 2012

Includes: Supplemental data

Journal Articles

PD-L1 Immuno-Gene Therapy Under Cell Fate Control: Persistence of Cellular Delivery Vehicle and Transgene Expression.

Shoba Amarnath, PhD, James CM Wang, Paul R. Massey, James L. Riley, Bruce Levine, PhD, Carl H. June, MD, Jeffrey A. Medin, PhD, Daniel Fowler, MD

Blood (2009) 114 (22): 3580.

https://doi.org/10.1182/blood.V114.22.3580.3580

Published: 2009

Journal Articles

Adoptive Transfer of Umbilical Cord Blood (UCB)-Derived Regulatory T Cells (Tregs) to Recipients of Nonmyeloablative Unrelated Double UCB Transplantation.

Claudio Brunstein, Keli L. Hippen, David H. McKenna, Qing Cao, Julie Curtsinger, Darin Sumstad, Bruce L. Levine, PhD, James L. Riley, Carl H. June, MD, Jeffrey S. Miller, Bruce R. Blazar, John E. Wagner

Blood (2009) 114 (22): 513.

https://doi.org/10.1182/blood.V114.22.513.513

Published: 2009

Journal Articles

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

Keli L. Hippen, Paul Harker-Murray, Stephen B. Porter, Sarah C. Merkel, Aryel Londer, Dawn K. Taylor, Megan Bina, Angela Panoskaltsis-Mortari, Pablo Rubinstein, Nico Van Rooijen, Tatiana N. Golovina, Megan M. Suhoski, Jeffrey S. Miller, John E. Wagner, Carl H. June, James L. Riley, Bruce R. Blazar

Blood (2008) 112 (7): 2847–2857.

https://doi.org/10.1182/blood-2008-01-132951

Published: 2008

Includes: Supplemental data

Journal Articles

RNA fingerprints provide direct evidence for the inhibitory role of TGFβ and PD-1 on CD4 + T cells in Hodgkin lymphoma

Jens M. Chemnitz, Daniela Eggle, Julia Driesen, Sabine Classen, James L. Riley, Svenja Debey-Pascher, Marc Beyer, Alexey Popov, Thomas Zander, Joachim L. Schultze

Blood (2007) 110 (9): 3226–3233.

https://doi.org/10.1182/blood-2006-12-064360

Published: 2007

Includes: Supplemental data

Journal Articles

Chimeric Immunoreceptor (T-Body) Targeting of Acute B-Cell Lymphoblastic Leukemia (B-ALL) through Lentivirus Engineering of Primary Human T Cells.

Michael C. Milone, MD, PhD, Jonathan Fish, MD, Carmine Carpenito, PhD, Mehdi Lakal, BS, Ella Ofori, BS, Gwenn Danet-Desnoyers, PhD, James L. Riley, PhD, Stephan A. Grupp, MD, PhD, Carl H. June, MD

Blood (2006) 108 (11): 3267.

https://doi.org/10.1182/blood.V108.11.3267.3267

Published: 2006

Journal Articles

The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation

James L. Riley, Carl H. June

Blood (2005) 105 (1): 13–21.

https://doi.org/10.1182/blood-2004-04-1596

Published: 2005

Journal Articles

CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct Mechanisms.

Jens M. Chemnitz, James L. Riley, Kenneth A. Frauwirth, Inbal Braunstein, Sumire V. Kobayashi, Peter S. Linsley, Craig B. Thompson, Richard V. Parry

Blood (2004) 104 (11): 2657.

https://doi.org/10.1182/blood.V104.11.2657.2657

Published: 2004

NARROW

Robust expansion of HIV CAR T cells following antigen boosting in ART-suppressed nonhuman primates

In Vitro Induction of Human Regulatory T-Cells (iTregs) Using Conditions of Low Tryptophan Plus Kynurenines

miR-146b antagomir–treated human Tregs acquire increased GVHD inhibitory potency

Umbilical cord blood–derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality

Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease

Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4 + T cells from HIV-1 infection

TCR affinity and specificity requirements for human regulatory T-cell function

PD-L1 Immuno-Gene Therapy Under Cell Fate Control: Persistence of Cellular Delivery Vehicle and Transgene Expression.

Adoptive Transfer of Umbilical Cord Blood (UCB)-Derived Regulatory T Cells (Tregs) to Recipients of Nonmyeloablative Unrelated Double UCB Transplantation.

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

RNA fingerprints provide direct evidence for the inhibitory role of TGFβ and PD-1 on CD4 + T cells in Hodgkin lymphoma

Chimeric Immunoreceptor (T-Body) Targeting of Acute B-Cell Lymphoblastic Leukemia (B-ALL) through Lentivirus Engineering of Primary Human T Cells.

The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation

CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct Mechanisms.

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American Society of Hematology

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American Society of Hematology

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