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Yangbing Zhao
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Journal Articles

First-in-Human Assessment of Feasibility and Safety of Multiplexed Genetic Engineering of Autologous T Cells Expressing NY-ESO -1 TCR and CRISPR/Cas9 Gene Edited to Eliminate Endogenous TCR and PD-1 (NYCE T cells) in Advanced Multiple Myeloma (MM) and Sarcoma

Edward A. Stadtmauer, MD FACP, Adam D. Cohen, MD, Kristy Weber, MD, Simon F Lacey, PhD, Vanessa E. Gonzalez, J. Joseph Melenhorst, PhD, Joseph A Fraietta, PhD, Gabriela Plesa, MD, Joanne Shea, Tina Matlawski, RN, Amanda Cervini, RN, Patricia Mangan, CRNP, Avery Gaymon, Stephanie Desjardins, Eric Lancaster, MD, January Salas-Mckee, Megan M. Suhoski, PhD, Andrew Fesnak, MD, Matthew O'Rourke, Anne Lamontagne, Don L. Siegel, MD PhD, Regina M Young, PhD, Anne Chew, PhD, Christopher L Nobles, PhD, Frederic D. Bushman, PhD, Howard Y. Chang, MD PhD, Ansuman T. Satpathy, MD PhD, Yangbing Zhao, PhD MD, Wei-Ting Hwang, PhD, Elizabeth O. Hexner, MDMS, Carl H June, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 49.
https://doi.org/10.1182/blood-2019-122374
Published: 2019
Journal Articles

Clinical Evidence That Deficiency of the Methylcytosine Dioxygenase TET2 Gene Promotes the Clonal Expansion and Therapeutic Efficacy of CD19-Directed T Cells

Joseph A Fraietta, PhD, Christopher L Nobles, PhD, Morgan A Sammons, PhD, Shannon A. Carty, MD, Stefan M Lundh, BS, Tyler Reich, Alexandria P Cogdill, BS, MB, Mercy Gohil, Jennifer J.D. Morrissette, PhD, Irina Kulikovskaya, Farzana Nazimuddin, MS, Minnal Gupta, Yan Wang, PhD, Xiaojun Liu, Regina M Young, PhD, David E Ambrose, Martha S Jordan, PhD, Katherine T Marcucci, PhD, Bruce L Levine, PhD, Yangbing Zhao, PhD MD, Michael Kalos, PhD, David L Porter, MD, Simon F Lacey, PhD BS, Shelley L Berger, PhD BS, Frederic D Bushman, PhD, Carl H June, MD, J. Joseph Melenhorst, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1909.
https://doi.org/10.1182/blood.V130.Suppl_1.1909.1909
Published: 2017
Journal Articles

Multiplex Cripsr/Cas9 Genome Editing to Generate Potent Universal CART and PD1-Deficient Cells Against Leukemia

Jiangtao Ren, PhD, Xiaojun Liu, Master, Chongyun Fang, PhD, Shuguang Jiang, PhD, Carl H. June, MD, Yangbing Zhao, PhD MD
Journal: Blood
Blood (2015) 126 (23): 4280.
https://doi.org/10.1182/blood.V126.23.4280.4280
Published: 2015
Journal Articles

A Novel Small Animal Model to Test on-Target Off-Tumor Cytoxicity of Adoptive Immune Therapies

Mauro Castellarin, PhD, Joseph A. Fraietta, PhD, Jihyun Lee, PhD, John Scholler, Yangbing Zhao, PhD MD, Carl H. June, MD
Journal: Blood
Blood (2015) 126 (23): 5432.
https://doi.org/10.1182/blood.V126.23.5432.5432
Published: 2015
Journal Articles

Improved Anti-Leukemia Activities of Adoptively Transferred T Cells Expressing Bites

Xiaojun Liu, Master, David M. Barrett, MD PhD, Shuguang Jiang, PhD, Chongyun Fang, PhD, Stephan A. Grupp, MD PhD, Carl H. June, MD, Yangbing Zhao, PhD MD
Journal: Blood
Blood (2015) 126 (23): 4431.
https://doi.org/10.1182/blood.V126.23.4431.4431
Published: 2015
Journal Articles

Distinct Signaling By Chimeric Antigen Receptors (CARs) Containing CD28 Signaling Domain Versus 4-1BB In Primary Human T Cells

Omkar Uday Kawalekar, MS, BS, Avery D. Posey, Jr., Joseph Fraietta, Jihyun Lee, John Scholler, Yangbing Zhao, Carl H. June, MD
Journal: Blood
Blood (2013) 122 (21): 2902.
https://doi.org/10.1182/blood.V122.21.2902.2902
Published: 2013
Journal Articles

TCR affinity and specificity requirements for human regulatory T-cell function

Gabriela Plesa, Lingjie Zheng, Andrew Medvec, Caleph B. Wilson, Camila Robles-Oteiza, Nathaniel Liddy, Alan D. Bennett, Jessie Gavarret, Annelise Vuidepot, Yangbing Zhao, Bruce R. Blazar, Bent K. Jakobsen, James L. Riley
Journal: Blood
Blood (2012) 119 (15): 3420–3430.
https://doi.org/10.1182/blood-2011-09-377051
Published: 2012
Includes: Supplemental data
Journal Articles

Construction and Pre-Clinical Evaluation of An Anti-CD19 Chimeric Antigen Receptor

James Kochenderfer, M.D., Steven Feldman, PhD, Yangbing Zhao, PhD, Hui Xu, Mary Black, Richard Morgan, PhD, Mark Dudley, PhD, Wyndham Wilson, MD, PhD, Steven Rosenberg, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 4623.
https://doi.org/10.1182/blood.V112.11.4623.4623
Published: 2008
Journal Articles

Inhibition of invariant chain expression in dendritic cells presenting endogenous antigens stimulates CD4 + T-cell responses and tumor immunity

Yangbing Zhao, David Boczkowski, Smita K. Nair, Eli Gilboa
Journal: Blood
Blood (2003) 102 (12): 4137–4142.
https://doi.org/10.1182/blood-2003-06-1867
Published: 2003