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Journal Articles

CD75s Represents a Therapeutic Target for Antibody-Based Immunotherapy of B Cell Lymphoma and Multiple Myeloma

Katja Klausz, PhD, Malena Buck, Steffen Krohn, Renate Burger, PhD, Christian Kellner, PhD, Martin Gramatzki, MD, Matthias Peipp, PhD

Blood (2017) 130 (Supplement 1): 1810.

https://doi.org/10.1182/blood.V130.Suppl_1.1810.1810

Published: 2017

Journal Articles

The Novel ADCC-Optimized Human CD54 (ICAM-1) Antibody MSH-TP15e Has Potent Anti-Myeloma Activity

Katja Klausz, PhD, Renate Burger, PhD, Christian Kellner, PhD, Andreas Guenther, MD, Matthias Peipp, PhD, Martin Gramatzki, MD

Blood (2016) 128 (22): 4471.

https://doi.org/10.1182/blood.V128.22.4471.4471

Published: 2016

Journal Articles

A Novel ICAM-1/CD54 Antibody Identified By Phage Display with Potent Pre-Clinical Anti-Myeloma Activity

Katja Klausz, PhD, Renate Burger, PhD, Christian Kellner, PhD, Matthias Peipp, PhD, Martin Gramatzki, MD

Blood (2014) 124 (21): 2095.

https://doi.org/10.1182/blood.V124.21.2095.2095

Published: 2014

Journal Articles

MSH-TP15 Identified By Phage Display Technology Detects a Target Structure For Antibody-Mediated Killing In Multiple Myeloma

Katja Klausz, PhD, Renate Burger, PhD, Christian Kellner, PhD, Pia Glorius, PhD, Andreas Guenther, MD, Matthias Peipp, PhD, Martin Gramatzki, MD

Blood (2013) 122 (21): 4442.

https://doi.org/10.1182/blood.V122.21.4442.4442

Published: 2013

Journal Articles

Selective Inhibition Of The PI3K-Alpha Isoform Blocks Myeloma Cell Growth and Survival

Andreas Guenther, MD, Renate Burger, PhD, Wolfram Klapper, Matthias Staudinger, PhD, Martin Gramatzki, MD

Blood (2013) 122 (21): 5364.

https://doi.org/10.1182/blood.V122.21.5364.5364

Published: 2013

Journal Articles

The CD317-Targeted Immunotoxin HM1.24-ETA′ Efficiently Eliminates Malignant Plasma Cells in Vitro and in Vivo

Matthias Staudinger, Pia Glorius, Christian Kellner, Andreas Guenther, Roland Repp, Renate Burger, Martin Gramatzki, Matthias Peipp

Blood (2012) 120 (21): 1838.

https://doi.org/10.1182/blood.V120.21.1838.1838

Published: 2012

Journal Articles

The JAK1/2 Inhibitor Ruxolitinib Kills Malignant Plasma Cells and Is Synergistic with PI3K and mToR Inhibitors

Renate Burger, Tim Bugdahn, Matthias Staudinger, Anna Lena Michaelis, Matthias Peipp, Andreas Guenther, Martin Gramatzki

Blood (2012) 120 (21): 1844.

https://doi.org/10.1182/blood.V120.21.1844.1844

Published: 2012

Journal Articles

Inhibitors of Mtor and PI3K Synergistically Block Plasmacytoma Cell Growth

Andreas Guenther, Renate Burger, Wolfram Klapper, MD, Matthias Staudinger, Kathrin Richter, Tanja Ahrens, Martin Gramatzki

Blood (2011) 118 (21): 2903.

https://doi.org/10.1182/blood.V118.21.2903.2903

Published: 2011

Journal Articles

The Novel JAK2 Inhibitor NVP-BSK805 Has Cytotoxic Activity on Malignant Plasma Cells

Renate Burger, PhD, Franziska Rademacher, Matthias Staudinger, PhD, Matthias Peipp, PhD, Andreas Güunther, MD, Martin Gramatzki, MD

Blood (2010) 116 (21): 2993.

https://doi.org/10.1182/blood.V116.21.2993.2993

Published: 2010

Journal Articles

Mtor and PI3K Inhibitors Block Myeloma Cell Growth in a Synergistic Manner.

Andreas Guenther, Renate Burger, Wolfram Klapper, Markus Tiemann, Frank Bakker, Katja Brocke-Heidrich, Friedemann Horn, Martin Gramatzki

Blood (2009) 114 (22): 1843.

https://doi.org/10.1182/blood.V114.22.1843.1843

Published: 2009

Journal Articles

Phase I/II Study with Single Agent Everolimus (RAD001) in Patients with Relapsed or Refractory Multiple myeloma.

Andreas Guenther, Philipp Baumann, Renate Burger, Wolfram Klapper, Ralf Schmidmaier, Martin Gramatzki

Blood (2009) 114 (22): 3850.

https://doi.org/10.1182/blood.V114.22.3850.3850

Published: 2009

Journal Articles

The Immunotoxin HM1.24-ETA′ Is a Potent Inducer of Apoptosis in Malignant Plasma Cells

Matthias Staudinger, Anja Muskulus, Renate Burger, Andreas Guenther, Roland Repp, Martin Gramatzki, Matthias Peipp

Blood (2008) 112 (11): 3658.

https://doi.org/10.1182/blood.V112.11.3658.3658

Published: 2008

Journal Articles

The Green Tea Polyphenol Epigallocatechin Gallate (EGCG) Antagonizes the Inhibitory Effect of Bortezomib on Myeloma Cells.

Renate Burger, PhD, Hanna Czekalla, Tanja Ahrens, Kathrin Richter, Andreas Guenther, MD, Martin Gramatzki, MD

Blood (2007) 110 (11): 4794.

https://doi.org/10.1182/blood.V110.11.4794.4794

Published: 2007

Journal Articles

Interleukin-6–dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer

Dennis Löffler, Katja Brocke-Heidrich, Gabriele Pfeifer, Claudia Stocsits, Jörg Hackermüller, Antje K. Kretzschmar, Renate Burger, Martin Gramatzki, Conny Blumert, Kay Bauer, Helena Cvijic, A. Kerstin Ullmann, Peter F. Stadler, Friedemann Horn

Blood (2007) 110 (4): 1330–1333.

https://doi.org/10.1182/blood-2007-03-081133

Published: 2007

Includes: Supplemental data

Journal Articles

Inhibitors of mToR Mediate Anti-Myeloma Activity by Apoptosis through the Extrinsic Pathway.

Andreas Günther, MD, Markus Tiemann, M.D., Frank Bakker, Ph.D., Wolfgang Baum, Ph.D., Katja Brocke-Heidrich, Ph.D., Friedemann Horn, Ph.D., Renate Burger, Ph.D., Martin Gramatzki, M.D.

Blood (2006) 108 (11): 3428.

https://doi.org/10.1182/blood.V108.11.3428.3428

Published: 2006

Journal Articles

Green Tea Polyphenol (−)-Epigallocatechin Gallate Inhibits IL-6 Mediated Signalling Pathways in Human Myeloma Cells.

Renate Burger, PhD, Hanna Czekalla, Kathrin Richter, Tanja Ahrens, Andreas Guenther, MD, Martin Gramatzki, MD

Blood (2006) 108 (11): 5049.

https://doi.org/10.1182/blood.V108.11.5049.5049

Published: 2006

Journal Articles

Zoledronate Exerts Direct Antiproliferative and Apoptotic Effects on Human Myeloma Cells In Vitro and In Vivo .

Andreas Guenther, MD, Sharon Gordon, PhD, Frank Bakker, PhD, Renate Burger, PhD, Markus Tiemann, MD, Jonathan R. Green, MD, Michael Rogers, PhD, Martin Gramatzki, MD

Blood (2005) 106 (11): 3387.

https://doi.org/10.1182/blood.V106.11.3387.3387

Published: 2005

Journal Articles

The JAK Inhibitor INCB20 Induces Antiproliferative and Apoptotic Effects in Human Myeloma Cells In Vitro and In Vivo .

Renate Burger, PhD, Steven Legouill, MD, Yu-Tzu Tai, PhD, Reshma Shringarpure, PhD, Klaus Podar, MD, PhD, Laurence Catley, MD, Pierfrancesco Tassone, MD, Paola Neri, MD, Teru Hideshima, MD, Dharminder Chauhan, PhD, Eian Caulder, BS, Kris Vaddi, PhD, Claire L. Neilan, PhD, Martin Gramatzki, MD, Jordan S. Fridman, PhD, Kenneth C. Anderson, MD

Blood (2005) 106 (11): 3357.

https://doi.org/10.1182/blood.V106.11.3357.3357

Published: 2005

Journal Articles

Synergistic Inhibition of Myeloma Cell Growth by Combinations of Dexamethasone with Other Anti-Myeloma Agents.

Frank Bakker, PhD, Andrea Ott, Kathrin Richter, Tanja Ahrens, Andreas Guenther, MD, Renate Burger, PhD, Martin Gramatzki, MD

Blood (2005) 106 (11): 5105.

https://doi.org/10.1182/blood.V106.11.5105.5105

Published: 2005

Journal Articles

Novel Model To Evaluate Changes in Gene Expression Profile of Myeloma Cells In Vivo Following Interaction with Human BM Microenvironment.

Paola Neri, MD, Pierfrancesco Tassone, MD, Masood A. Shammas, PhD, Daniel R. Carrasco, MD, Renate Burger, PhD, Constantine S. Mitsdiades, MD, Simona Blotta, MD, Rao H. Prabhala, PhD, Laurence Catley, MD, Salvatore Venuta, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2005) 106 (11): 2490.

https://doi.org/10.1182/blood.V106.11.2490.2490

Published: 2005

NARROW

CD75s Represents a Therapeutic Target for Antibody-Based Immunotherapy of B Cell Lymphoma and Multiple Myeloma

The Novel ADCC-Optimized Human CD54 (ICAM-1) Antibody MSH-TP15e Has Potent Anti-Myeloma Activity

A Novel ICAM-1/CD54 Antibody Identified By Phage Display with Potent Pre-Clinical Anti-Myeloma Activity

MSH-TP15 Identified By Phage Display Technology Detects a Target Structure For Antibody-Mediated Killing In Multiple Myeloma

Selective Inhibition Of The PI3K-Alpha Isoform Blocks Myeloma Cell Growth and Survival

The CD317-Targeted Immunotoxin HM1.24-ETA′ Efficiently Eliminates Malignant Plasma Cells in Vitro and in Vivo

The JAK1/2 Inhibitor Ruxolitinib Kills Malignant Plasma Cells and Is Synergistic with PI3K and mToR Inhibitors

Inhibitors of Mtor and PI3K Synergistically Block Plasmacytoma Cell Growth

The Novel JAK2 Inhibitor NVP-BSK805 Has Cytotoxic Activity on Malignant Plasma Cells

Mtor and PI3K Inhibitors Block Myeloma Cell Growth in a Synergistic Manner.

Phase I/II Study with Single Agent Everolimus (RAD001) in Patients with Relapsed or Refractory Multiple myeloma.

The Immunotoxin HM1.24-ETA′ Is a Potent Inducer of Apoptosis in Malignant Plasma Cells

The Green Tea Polyphenol Epigallocatechin Gallate (EGCG) Antagonizes the Inhibitory Effect of Bortezomib on Myeloma Cells.

Interleukin-6–dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer

Inhibitors of mToR Mediate Anti-Myeloma Activity by Apoptosis through the Extrinsic Pathway.

Green Tea Polyphenol (−)-Epigallocatechin Gallate Inhibits IL-6 Mediated Signalling Pathways in Human Myeloma Cells.

Zoledronate Exerts Direct Antiproliferative and Apoptotic Effects on Human Myeloma Cells In Vitro and In Vivo .

The JAK Inhibitor INCB20 Induces Antiproliferative and Apoptotic Effects in Human Myeloma Cells In Vitro and In Vivo .

Synergistic Inhibition of Myeloma Cell Growth by Combinations of Dexamethasone with Other Anti-Myeloma Agents.

Novel Model To Evaluate Changes in Gene Expression Profile of Myeloma Cells In Vivo Following Interaction with Human BM Microenvironment.

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American Society of Hematology

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American Society of Hematology

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