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Journal Articles

Budesonide Added to Post-Transplantation Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for Prevention of Graft-Versus-Host Disease

Pongthep Vittayawacharin, Deepa Jeyakumar, Benjamin J. Lee, Jean Doh, Shawn Griffin, Richard A. Van Etten, Piyanuch Kongtim, Stefan Ciurea

Blood (2023) 142 (Supplement 1): 2192.

https://doi.org/10.1182/blood-2023-190530

Published: 2023

Journal Articles

Overexpression of Calreticulin Impairs Self-Renewal Capacity of Hematopoietic Stem Cells

Stefan Brooks, Sarah Morse, MS, Brianna Craver, MS, Hew Yeng Lai, Thanh Kim Nguyen, PhD, Daniel Kim, Angela G. Fleischman, MD PhD, Prasanthi Tata, Nilamani Jena, PhD, Zhong-Ying Liu, Richard A. Van Etten, MD PhD

Blood (2017) 130 (Supplement 1): 4937.

https://doi.org/10.1182/blood.V130.Suppl_1.4937.4937

Published: 2017

Journal Articles

The MEK/ERK Inhibitor Trametinib Reduces Fibrosis in a Transduction-Transplantation Model of Mutated Calreticulin

Thanh Kim Nguyen, PhD, Prasanthi Tata, Stefan Brooks, BA, Nilamani Jena, PhD, Sarah J Morse, MS, BS, Zhong-ying Liu, Hew Yeng Lai, BS, Sherif Rezk, MD, Richard A. Van Etten, MD PhD, Angela G Fleischman, MD PhD

Blood (2016) 128 (22): 635.

https://doi.org/10.1182/blood.V128.22.635.635

Published: 2016

Journal Articles

Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1

Shengqing Gu, Wayne W. Chan, Golam Mohi, Joel Rosenbaum, Azin Sayad, Zhibin Lu, Carl Virtanen, Shaoguang Li, Benjamin G. Neel, Richard A. Van Etten

Blood (2016) 127 (14): 1803–1813.

https://doi.org/10.1182/blood-2015-06-653006

Published: 2016

Includes: Supplemental data

Journal Articles

Focal Adhesion Kinase Inhibitors Reverse the Stromal Adhesion Phenotype of Ikaros-Mutant B-ALL, Induce Apopotosis, and Synergize with ABL1 Tyrosine Kinase Inhibitors: A New Paradigm for Pathogenesis and Therapy of High-Risk B-ALL

Ila Joshi, PhD, Nilamani Jena, PhD, Toshimi Yoshida, PhD, Leto Paraskevopoulou, BS, Zhihong Zhang, PhD, Zhong-Ying Liu, MDPhD, Shane Korber, Daniela S. Krause, MD, Irina M. Shapiro, PhD, David T. Weaver, PhD, Jonathan A. Pachter, PhD, Elisabeth M. Paietta, PhD, Richard A. Van Etten, MDPhD, Katia Georgopoulos, PhD

Blood (2014) 124 (21): 285.

https://doi.org/10.1182/blood.V124.21.285.285

Published: 2014

Journal Articles

The Microanatomy of the Leukemic Stem Cell Niche in Murine Chronic Myelogenous Leukemia

Melanie Meister, Joel A Spencer, PhD, Juwell Wu, Cher Zhao, Lymperi Stefania, PhD, Francesca Ferraro, MD, Cristina Lo Celso, PhD, David T. Scadden, MD, Richard A. Van Etten, MDPhD, Charles Lin, PhD, Daniela S. Krause, MD

Blood (2014) 124 (21): 351.

https://doi.org/10.1182/blood.V124.21.351.351

Published: 2014

Journal Articles

The Vascular Niche Is Involved in Regulating Leukemic Stem Cells in Murine Chronic Myelogenous Leukemia

Djamel Aggoune, John L. Magnani, PhD, Richard A. Van Etten, MDPhD, Daniela S. Krause, MD

Blood (2014) 124 (21): 516.

https://doi.org/10.1182/blood.V124.21.516.516

Published: 2014

Journal Articles

IKK-dependent activation of NF-κB contributes to myeloid and lymphoid leukemogenesis by BCR-ABL1

Mo-Ying Hsieh, Richard A. Van Etten

Blood (2014) 123 (15): 2401–2411.

https://doi.org/10.1182/blood-2014-01-547943

Published: 2014

Includes: Supplemental data

Journal Articles

Selectins and their ligands are required for homing and engraftment of BCR-ABL1 + leukemic stem cells in the bone marrow niche

Daniela S. Krause, Katherine Lazarides, Juliana B. Lewis, Ulrich H. von Andrian, Richard A. Van Etten

Blood (2014) 123 (9): 1361–1371.

https://doi.org/10.1182/blood-2013-11-538694

Published: 2014

Includes: Supplemental data

Journal Articles

BCR-ABL1 + Leukemic Stem Cells Are Dependent On Selectin-Ligand Interactions For Engraftment In The Bone Marrow Niche

Daniela S. Krause, M.D., Ph.D., Katherine Lazarides, B.S., Juliana B. Lewis, Ph.D., Ulrich H. von Andrian, M.D., Ph.D., David T. Scadden, M.D., Richard A. Van Etten, M.D., Ph.D.

Blood (2013) 122 (21): 2703.

https://doi.org/10.1182/blood.V122.21.2703.2703

Published: 2013

Journal Articles

Ikaros Mutation Confers Integrin-Dependent Survival Of Pre-B Cells and Progression To Acute Lymphoblastic Leukemia

Nilamani Jena, Ph.D., Ila Joshi, Ph.D., Toshimi Yoshida, Ph.D., Xiaoqing Qi, Ph.D., Jiangwen Zhang, Ph.D., Katia Georgopoulos, Ph.D., Richard A. Van Etten, M.D., Ph.D.

Blood (2013) 122 (21): 1259.

https://doi.org/10.1182/blood.V122.21.1259.1259

Published: 2013

Journal Articles

Differential Regulation of Myeloid Leukemias by the Bone Marrow Microenvironment

Daniela S. Krause, M.D., Ph.D., Keertik Fulzele, PhD, Andre Catic, MD PhD, Michael Hurley, Sanon Lezeau, Eyal C. Attar, MD, Joy Y. Wu, Herbert Yih-Fuu Lin, MD, PhD, Paola Divieti-Pajevic, MD PhD, Robert Hasserjian, MD, Ernestina Schipani, MD, Richard A. Van Etten, MD PhD, David T. Scadden, MD

Blood (2012) 120 (21): 1245.

https://doi.org/10.1182/blood.V120.21.1245.1245

Published: 2012

Journal Articles

Essential role for Stat5a/b in myeloproliferative neoplasms induced by BCR-ABL1 and JAK2 V617F in mice

Christoph Walz, Wesam Ahmed, Katherine Lazarides, Monica Betancur, Nihal Patel, Lothar Hennighausen, Virginia M. Zaleskas, Richard A. Van Etten

Blood (2012) 119 (15): 3550–3560.

https://doi.org/10.1182/blood-2011-12-397554

Published: 2012

Includes: Supplemental data

Journal Articles

Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia

Katie O'Callaghan, Lydia Lee, Nga Nguyen, Mo-Ying Hsieh, Nicole C. Kaneider, Andreas K. Klein, Kellie Sprague, Richard A. Van Etten, Athan Kuliopulos, Lidija Covic

Blood (2012) 119 (7): 1717–1725.

https://doi.org/10.1182/blood-2011-04-347518

Published: 2012

Includes: Supplemental data

Journal Articles

Distinct graft-versus-leukemic stem cell effects of early or delayed donor leukocyte infusions in a mouse chronic myeloid leukemia model

Yi-Fen Lu, L. Cristina Gavrilescu, Monica Betancur, Katherine Lazarides, Hans Klingemann, Richard A. Van Etten

Blood (2012) 119 (1): 273–284.

https://doi.org/10.1182/blood-2011-01-331009

Published: 2012

Includes: Supplemental data

Journal Articles

Targeting CXCR4 with Cell-Penetrating Pepducins Enhances Survival in Disseminated Lymphoma

Lidija Covic, Katie M O’Callaghan, PhD, Nga Ngyen, Hsieh Mo-Ying, Andreas K. Klein, MD, Kellie Sprague, MD, Richard A. Van Etten, MD PhD, Athan Kuliopulos, MD, PhD

Blood (2011) 118 (21): 4244.

https://doi.org/10.1182/blood.V118.21.4244.4244

Published: 2011

Journal Articles

Outcomes in Allogeneic Hematopoietic Stem Cell Transplant Patients ≥ 60 Years of Age with a Novel Reduced Intensity Conditioning Regimen Incorporating Extracorporeal Photopheresis,

Furha I. Cossor, MD, Sandy Wong, MD, Kenneth B Miller, MD, Deborah Black, RN, Raymond L. Comenzo, MD, Andreas K. Klein, MD, Alanna Klekar, RN, Valerie Relias, PharmD, Hedy Smith, MD, PhD, Kellie Sprague, MD, Karen M Switkowski, MS, MPH, Richard A. Van Etten, MD PhD, Hans-Georg Klingemann, MD, PhD

Blood (2011) 118 (21): 4153.

https://doi.org/10.1182/blood.V118.21.4153.4153

Published: 2011

Journal Articles

A Phase 1 Study of DCC-2036, a Novel Oral Inhibitor of BCR-ABL Kinase, in Patients with Philadelphia Chromosome Positive (Ph + ) Leukemias Including Patients with T315I Mutation

Jorge E. Cortes, Moshe Talpaz, MD, Hagop M Kantarjian, Hedy Smith, MD, PhD, Dale Bixby, MD, PhD, Usha Rafferty, MS, Mark S. Berger, MD, Scott C. Wise, MS, Tom J. Rutkoski, Ph.D, Bryan Smith, Ph.D, Richard A. Van Etten, MD PhD

Blood (2011) 118 (21): 601.

https://doi.org/10.1182/blood.V118.21.601.601

Published: 2011

Journal Articles

Parathyroid Hormone-Induced Modulation of the Bone Marrow Microenvironment Reduces Leukemic Stem Cells in Murine Chronic Myelogenous-Leukemia-Like Disease Via a TGFbeta-Dependent Pathway

Daniela S. Krause, MD, PhD, Keertik Fulzele, PhD, Andre Catic, MD PhD, Michael Hurley, Sanon Lezeau, Robert Hasserjian, MD, Joy Wu, MD PhD, Paola Divieti-Pajevic, MD PhD, Richard A. Van Etten, MD PhD, Ernestina Schipani, MD, David T. Scadden, MD

Blood (2011) 118 (21): 1670.

https://doi.org/10.1182/blood.V118.21.1670.1670

Published: 2011

Journal Articles

CDK6 kinase activity is required for thymocyte development

Miaofen G. Hu, Amit Deshpande, Nicolette Schlichting, Elisabeth A. Hinds, Changchuin Mao, Marei Dose, Guo-fu Hu, Richard A. Van Etten, Fotini Gounari, Philip W. Hinds

Blood (2011) 117 (23): 6120–6131.

https://doi.org/10.1182/blood-2010-08-300517

Published: 2011

Includes: Supplemental data

NARROW

Budesonide Added to Post-Transplantation Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for Prevention of Graft-Versus-Host Disease

Overexpression of Calreticulin Impairs Self-Renewal Capacity of Hematopoietic Stem Cells

The MEK/ERK Inhibitor Trametinib Reduces Fibrosis in a Transduction-Transplantation Model of Mutated Calreticulin

Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1

Focal Adhesion Kinase Inhibitors Reverse the Stromal Adhesion Phenotype of Ikaros-Mutant B-ALL, Induce Apopotosis, and Synergize with ABL1 Tyrosine Kinase Inhibitors: A New Paradigm for Pathogenesis and Therapy of High-Risk B-ALL

The Microanatomy of the Leukemic Stem Cell Niche in Murine Chronic Myelogenous Leukemia

The Vascular Niche Is Involved in Regulating Leukemic Stem Cells in Murine Chronic Myelogenous Leukemia

IKK-dependent activation of NF-κB contributes to myeloid and lymphoid leukemogenesis by BCR-ABL1

Selectins and their ligands are required for homing and engraftment of BCR-ABL1 + leukemic stem cells in the bone marrow niche

BCR-ABL1 + Leukemic Stem Cells Are Dependent On Selectin-Ligand Interactions For Engraftment In The Bone Marrow Niche

Ikaros Mutation Confers Integrin-Dependent Survival Of Pre-B Cells and Progression To Acute Lymphoblastic Leukemia

Differential Regulation of Myeloid Leukemias by the Bone Marrow Microenvironment

Essential role for Stat5a/b in myeloproliferative neoplasms induced by BCR-ABL1 and JAK2 V617F in mice

Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia

Distinct graft-versus-leukemic stem cell effects of early or delayed donor leukocyte infusions in a mouse chronic myeloid leukemia model

Targeting CXCR4 with Cell-Penetrating Pepducins Enhances Survival in Disseminated Lymphoma

Outcomes in Allogeneic Hematopoietic Stem Cell Transplant Patients ≥ 60 Years of Age with a Novel Reduced Intensity Conditioning Regimen Incorporating Extracorporeal Photopheresis,

A Phase 1 Study of DCC-2036, a Novel Oral Inhibitor of BCR-ABL Kinase, in Patients with Philadelphia Chromosome Positive (Ph + ) Leukemias Including Patients with T315I Mutation

Parathyroid Hormone-Induced Modulation of the Bone Marrow Microenvironment Reduces Leukemic Stem Cells in Murine Chronic Myelogenous-Leukemia-Like Disease Via a TGFbeta-Dependent Pathway

CDK6 kinase activity is required for thymocyte development

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American Society of Hematology

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American Society of Hematology

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