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John G. Kelton
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Journal Articles

Clinical and Serological Characteristics of Vaccine-Associated Immune Thrombocytopenia Following COVID-19 Vaccination

Reid C. Gallant, Melanie St John, Yang Liu, Madison Cranstone, John G. Kelton, Ishac Nazy, Donald Arnold
Journal: Blood
Blood (2024) 144 (Supplement 1): 1243.
https://doi.org/10.1182/blood-2024-194652
Published: 2024
Journal Articles

Evaluation of Bleeding Self-Assessments By Patients with Immune Thrombocytopenia (ITP): An Agreement Study

Bianca Clerici, Ngan Tang, Madison Cranstone, Yang Liu, Milena Hadzi-Tosev, Joanne Nixon, Melanie St John, Maryam Shirinzadeh, Erin Jamula, John G. Kelton, Donald Arnold
Journal: Blood
Blood (2023) 142 (Supplement 1): 3958.
https://doi.org/10.1182/blood-2023-187067
Published: 2023
Journal Articles

Treatment of Critical Bleeding Events in Patients with Immune Thrombocytopenia: A Systematic Review

Emily Sirotich, Saifur Chowdhury, Gordon Guyatt, Daya Gill, Dimpy Modi, Laura Venier, Kerolos Eisa, Carolyn E Beck, Vicky R. Breakey, Kerstin de Wit, Stephen Porter, Kathryn Elizabeth Webert, Adam Cuker, Clare O'Connor, Jennifer MacWhirter - DiRaimo, Justin Yan, Charles Manski, John G. Kelton, Matthew Kang, Gail Strachan, Ziauddin Hassan, Barbara Pruitt, Menaka Pai, Rachael F. Grace, Dale Paynter, Jay Charness, Nichola Cooper, Steven Fein, Hasmik Nazaryan, Arnav Agarwal, Ishaq Siddiqui, Russell Leong, Sushmitha Pallapothu, Aaron Wen, Emily Xu, Bonnie Liu, Preksha Rathod, Henry Kwon, Jared Dookie, Amirmohammad Shafiee, Rachel Couban, Donald Arnold
Journal: Blood
Blood (2023) 142 (Supplement 1): 7239.
https://doi.org/10.1182/blood-2023-179448
Published: 2023
Journal Articles

Longitudinal Characteristics of Anti-Platelet Factor 4 Immunoglobulin G in Vaccine-Induced Immune Thrombotic Thrombocytopenia

Angela Huynh, Donald M. Arnold, James W. Smith, Rumi Clare, Nikola Ivetic, Jane C. Moore, John G. Kelton, Ishac Nazy
Journal: Blood
Blood (2022) 140 (Supplement 1): 5640–5641.
https://doi.org/10.1182/blood-2022-167607
Published: 2022
Journal Articles

Pathogenic Antibodies in Heparin-Induced Thrombocytopenia Specifically Target an Immunodominant Region on Platelet Factor 4

Angela Huynh, PhD, Donald M. Arnold, MD, John G. Kelton, MD, Rumi Clare, BSc, Marina Ivanova, Ishac Nazy, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 219.
https://doi.org/10.1182/blood-2019-131462
Published: 2019
Journal Articles

Perioperative Eltrombopag or Intravenous Immune Globulin for Patients with Immune Thrombocytopenia: A Multicenter Randomized Trial

Donald M. Arnold, MD, Nancy Heddle, MSc, Richard Cook, Cyrus C. Hsia, MDBSc,FRCPC, Mark Blostein, MDFRCPC, Erin Jamula, MSc, Michelle Sholzberg, MDBSc,FRCPC,MSc, Yulia Lin, MD, Jeannine Kassis, MD, Loree Larratt, MD FRCP(C), Sufia Amini, MD, Martin R. Schipperus, Wendy Lim, MD MSc, Prakash Vishnu, MD, Margaret Warner, FRCPC, Julie Carruthers, MLT, B.Com(Hon), Shannon J Lane, MPH, Na Li, PhD, John G. Kelton, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 896.
https://doi.org/10.1182/blood-2019-122609
Published: 2019
Journal Articles

Managing antithrombotic therapy in immune thrombocytopenia: development of the TH2 risk assessment score

Clinical Trials & Observations
Amaris K. Balitsky, John G. Kelton, Donald M. Arnold
Journal: Blood
Blood (2018) 132 (25): 2684–2686.
https://doi.org/10.1182/blood-2018-08-868406
Published: 2018
Journal Articles

Fluid-Phase Immune Complexes Can Assemble and Activate Platelets in Heparin-Induced Thrombocytopenia

Angela Huynh, BSc, Donald M. Arnold, MD MSc, FRCPC, James W. Smith, Taylor D. Elliott, BSc, Hina Bhakta, John G. Kelton, MD, Ishac Nazy, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3746.
https://doi.org/10.1182/blood-2018-99-115037
Published: 2018
Journal Articles

Performance Characteristics of a Novel Platelet Viability Assay for Heparin-Induced Thrombocytopenia

Nikola Ivetic, BSc, James W. Smith, Angela Huynh, BSc, John G Kelton, MD FRCPC, Donald M Arnold, MD, Ishac Nazy, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3615.
https://doi.org/10.1182/blood.V130.Suppl_1.3615.3615
Published: 2017
Journal Articles

Emergency Management of Patients with Immune Thrombocytopenia and Severe Bleeding

Siraj Mithoowani, MD, Nishwa Shah, BHSc, Resham Ejaz, MD, Rebecca Barty, MLT, BA, MSc, Na Li, PhD, Ishac Nazy, PhD, John G Kelton, MD FRCPC, Donald M Arnold, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4852.
https://doi.org/10.1182/blood.V130.Suppl_1.4852.4852
Published: 2017
Journal Articles

Use of Anticoagulation in Patients with Immune Thrombocytopenia

Amaris K. Balitsky, John G Kelton, MD FRCPC, Ishac Nazy, PhD, Brandon Aubie, Rumi Clare, BSc, Anushka M Jaffer, BSc, Donald M Arnold, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2313.
https://doi.org/10.1182/blood.V130.Suppl_1.2313.2313
Published: 2017
Journal Articles

The Identification of the Amino Acids on Platelet Factor 4 That Bind Pathogenic Antibodies in Heparin-Induced Thrombocytopenia

Angela Huynh, BSc, Donald M Arnold, MD, Peter Horsewood, PhD, John G Kelton, MD FRCPC, Ishac Nazy, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 293.
https://doi.org/10.1182/blood.V130.Suppl_1.293.293
Published: 2017
Journal Articles

Megakaryocyte Apoptosis in the Bone Marrow of Patients with Immune Thrombocytopenia

John R Vrbensky, BSc, Ishac Nazy, PhD, Lisa J Toltl, PhD, Catherine Ross, MD, John G. Kelton, MD FRCPC, Donald M. Arnold, MD
Journal: Blood
Blood (2016) 128 (22): 1379.
https://doi.org/10.1182/blood.V128.22.1379.1379
Published: 2016
Journal Articles

Autoantibodies to Thrombopoietin and the Thrombopoietin Receptor in Patients with Immune Thrombocytopenia

Ishac Nazy, PhD, Jane C. Moore, BSc, MT, Rumi Clare, B.Sc., James W. Smith, BSc MT, Nikola Ivetic, BSc, Vanessa D'Souza, B.Sc., John G. Kelton, MD FRCPC, Donald M. Arnold, MD
Journal: Blood
Blood (2016) 128 (22): 2548.
https://doi.org/10.1182/blood.V128.22.2548.2548
Published: 2016
Journal Articles

The Mcmaster ITP Registry: Assessing the Prevalence, Clinical and Laboratory Features of Immune Thrombocytopenia

Donald M. Arnold, MD MSc, Rumi Clare, B.Sc., Mary Salib, MD, Robert Clayden, Grace Wang, MMath, Ishac Nazi, PhD, John G. Kelton, MD FRCPC
Journal: Blood
Blood (2014) 124 (21): 5008.
https://doi.org/10.1182/blood.V124.21.5008.5008
Published: 2014
Journal Articles

A Phase II Study Evaluating the Efficacy of Rituximab in the Management of Patients with Relapsed or Refractory TTP

Stephen Ronan Foley, MD FRCPC, Gail Rock, PhD MD, David Barth, MD FRCPC, Donald M. Arnold, MD MSc, Kathryn E Webert, MD FRCP(C), Paul R. Yenson, MD FRCPC, John G. Kelton, MD FRCPC, William Foster Clark, MD, Lihua Li
Journal: Blood
Blood (2014) 124 (21): 4191.
https://doi.org/10.1182/blood.V124.21.4191.4191
Published: 2014
Journal Articles

Low Level Platelet-Activating Antibodies in Patients Suspected of Having Heparin-Induced Thrombocytopenia but Testing Negative in the ”Gold Standard” Functional Test

Ishac Nazi, PhD, Donald M Arnold, MD, James W Smith, BSc, MT, Theodore E. Warkentin, MD, Jane C Moore, BSc, MT, Peter Horsewood, PhD, John G. Kelton, MD FRCPC
Journal: Blood
Blood (2014) 124 (21): 2757.
https://doi.org/10.1182/blood.V124.21.2757.2757
Published: 2014
Journal Articles

The effect of rituximab on vaccine responses in patients with immune thrombocytopenia

Ishac Nazi, John G. Kelton, Mark Larché, Denis P. Snider, Nancy M. Heddle, Mark A. Crowther, Richard J. Cook, Alan T. Tinmouth, Joy Mangel, Donald M. Arnold
Journal: Blood
Blood (2013) 122 (11): 1946–1953.
https://doi.org/10.1182/blood-2013-04-494096
Published: 2013
Journal Articles

Persistent Impairments in Humoral and Cellular Immunity in Patients with Immune Thrombocytopenia Treated with Rituximab: A Sub-Study of a Randomized Controlled Trial

Ishac Nazi, Ph.D., John G. Kelton, MD, FRCPC, Mark Larche, Ph.D., Denis P. Snider, Ph.D., Jane C. Moore, B.Sc., James W. Smith, B.Sc., Rumi Clare, B.Sc., Diana M. Moffatt, Joecyln Tufts, Donald M. Arnold, MD, MSc.
Journal: Blood
Blood (2012) 120 (21): 492.
https://doi.org/10.1182/blood.V120.21.492.492
Published: 2012
Journal Articles

A pilot randomized trial of adjuvant rituximab or placebo for nonsplenectomized patients with immune thrombocytopenia

Clinical Trials & Observations
Donald M. Arnold, Nancy M. Heddle, Julie Carruthers, Deborah J. Cook, Mark A. Crowther, Ralph M. Meyer, Yang Liu, Richard J. Cook, Anne McLeod, Janet A. MacEachern, Joy Mangel, David Anderson, Linda Vickars, Alan Tinmouth, Andre C. Schuh, John G. Kelton
Journal: Blood
Blood (2012) 119 (6): 1356–1362.
https://doi.org/10.1182/blood-2011-08-374777
Published: 2012