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Mark E. Dudley
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Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation

James N. Kochenderfer, Mark E. Dudley, Robert O. Carpenter, Sadik H. Kassim, Jeremy J. Rose, William G. Telford, Frances T. Hakim, David C. Halverson, Daniel H. Fowler, Nancy M. Hardy, Anthony R. Mato, Dennis D. Hickstein, Juan C. Gea-Banacloche, Steven Z. Pavletic, Claude Sportes, Irina Maric, Steven A. Feldman, Brenna G. Hansen, Jennifer S. Wilder, Bazetta Blacklock-Schuver, Bipulendu Jena, Michael R. Bishop, Ronald E. Gress, Steven A. Rosenberg
Journal: Blood
Blood (2013) 122 (25): 4129–4139.
https://doi.org/10.1182/blood-2013-08-519413
Published: 2013
Includes: Supplemental data
Journal Articles

Effective Treatment Of Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma With Autologous T Cells Genetically-Engineered To Express An Anti-CD19 Chimeric Antigen Receptor

James N. Kochenderfer, M.D., Mark E. Dudley, Ph.D., Sadik H. Kassim, Ph.D., Robert O. Carpenter, James C. Yang, MD, Giao Q. Phan, MD, Marybeth S. Hughes, MD, Richard M. Sherry, MD, Steven Feldman, Ph.D., David Spaner, MD, PhD, Debbie-Ann N. Nathan, RN, Kathleen E. Morton, RN, Mary Ann Toomey, RN, Steven A. Rosenberg, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 168.
https://doi.org/10.1182/blood.V122.21.168.168
Published: 2013
Journal Articles

Donor-Derived Anti-CD19 Chimeric-Antigen-Receptor-Expressing T Cells Cause Regression Of Malignancy Persisting After Allogeneic Hematopoietic Stem Cell Transplantation

James N Kochenderfer, M.D., Mark E. Dudley, Ph.D., Robert O. Carpenter, Sadik H Kassim, Ph.D., Jeremy J. Rose, William Telford, Ph.D., Frances T Hakim, PhD, David Halverson, MD, Daniel H. Fowler, MD, Nancy M. Hardy, MD, Anthony Mato, Dennis D. Hickstein, M.D., Juan Gea-Banacloche, MD, Steven Z. Pavletic, MD, Claude Sportes, MD, Irina Maric, MD, Steven Feldman, Ph.D., Brenna G Hansen, RN, Jennifer Wilder, RN, Bazetta Blacklock-Schuver, RN, Bipulendu Jena, PhD, Michael Bishop, MD, Steven A. Rosenberg, M.D., Ph.D., Ronald E. Gress, MD
Journal: Blood
Blood (2013) 122 (21): 151.
https://doi.org/10.1182/blood.V122.21.151.151
Published: 2013
Journal Articles

Levels of peripheral CD4 + FoxP3 + regulatory T cells are negatively associated with clinical response to adoptive immunotherapy of human cancer

Xin Yao, Mojgan Ahmadzadeh, Yong-Chen Lu, David J. Liewehr, Mark E. Dudley, Fang Liu, David S. Schrump, Seth M. Steinberg, Steven A. Rosenberg, Paul F. Robbins
Journal: Blood
Blood (2012) 119 (24): 5688–5696.
https://doi.org/10.1182/blood-2011-10-386482
Published: 2012
Includes: Supplemental data
Journal Articles

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells

Clinical Trials & Observations
James N. Kochenderfer, Mark E. Dudley, Steven A. Feldman, Wyndham H. Wilson, David E. Spaner, Irina Maric, Maryalice Stetler-Stevenson, Giao Q. Phan, Marybeth S. Hughes, Richard M. Sherry, James C. Yang, Udai S. Kammula, Laura Devillier, Robert Carpenter, Debbie-Ann N. Nathan, Richard A. Morgan, Carolyn Laurencot, Steven A. Rosenberg
Journal: Blood
Blood (2012) 119 (12): 2709–2720.
https://doi.org/10.1182/blood-2011-10-384388
Published: 2012
Includes: Supplemental data
Journal Articles

B-Cell Depletion, Remissions of Malignancy, and Cytokine-Associated Toxicity in a Clinical Trial of T Cells Genetically-Engineered to Express An Anti-CD19 Chimeric Antigen Receptor

James N Kochenderfer, Mark E. Dudley, Steven Feldman, Wyndham H. Wilson, MD, PhD, David Spaner, Laura Devillier, Robert Carpenter, Debbie-Ann N. Nathan, Irina Maric, Richard A. Morgan, Steven A. Rosenberg
Journal: Blood
Blood (2011) 118 (21): 167.
https://doi.org/10.1182/blood.V118.21.167.167
Published: 2011
Journal Articles

A Phase I Clinical Trial of Treatment of B-Cell Malignancies with Autologous Anti-CD19-CAR-Transduced T Cells

James N. Kochenderfer, Mark E. Dudley, Maryalice Stetler-Stevenson, Wyndham H. Wilson, John E. Janik, Debbie-Ann N. Nathan, Irina Maric, Mark Raffeld, Steven A. Feldman, Richard A. Morgan, Steven A. Rosenberg
Journal: Blood
Blood (2010) 116 (21): 2865.
https://doi.org/10.1182/blood.V116.21.2865.2865
Published: 2010
Journal Articles

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

Brief Report
James N. Kochenderfer, Wyndham H. Wilson, John E. Janik, Mark E. Dudley, Maryalice Stetler-Stevenson, Steven A. Feldman, Irina Maric, Mark Raffeld, Debbie-Ann N. Nathan, Brock J. Lanier, Richard A. Morgan, Steven A. Rosenberg
Journal: Blood
Blood (2010) 116 (20): 4099–4102.
https://doi.org/10.1182/blood-2010-04-281931
Published: 2010
Includes: Supplemental data
Journal Articles

Tumor antigen–specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

Mojgan Ahmadzadeh, Laura A. Johnson, Bianca Heemskerk, John R. Wunderlich, Mark E. Dudley, Donald E. White, Steven A. Rosenberg
Journal: Blood
Blood (2009) 114 (8): 1537–1544.
https://doi.org/10.1182/blood-2008-12-195792
Published: 2009
Journal Articles

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

Laura A. Johnson, Richard A. Morgan, Mark E. Dudley, Lydie Cassard, James C. Yang, Marybeth S. Hughes, Udai S. Kammula, Richard E. Royal, Richard M. Sherry, John R. Wunderlich, Chyi-Chia R. Lee, Nicholas P. Restifo, Susan L. Schwarz, Alexandria P. Cogdill, Rachel J. Bishop, Hung Kim, Carmen C. Brewer, Susan F. Rudy, Carter VanWaes, Jeremy L. Davis, Aarti Mathur, Robert T. Ripley, Debbie A. Nathan, Carolyn M. Laurencot, Steven A. Rosenberg
Journal: Blood
Blood (2009) 114 (3): 535–546.
https://doi.org/10.1182/blood-2009-03-211714
Published: 2009
Journal Articles

Warrior, miscreant, suicide: making better killers

Mark E. Dudley
Journal: Blood
Blood (2007) 110 (8): 2781–2782.
https://doi.org/10.1182/blood-2007-08-103846
Published: 2007
Journal Articles

Transition of late-stage effector T cells to CD27 + CD28 + tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy

Daniel J. Powell, Jr, Mark E. Dudley, Paul F. Robbins, Steven A. Rosenberg
Journal: Blood
Blood (2005) 105 (1): 241–250.
https://doi.org/10.1182/blood-2004-06-2482
Published: 2005