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Journal Articles

CalDAG-GEFI deficiency protects mice in a novel model of FcγRIIA-mediated thrombosis and thrombocytopenia

Moritz Stolla, Lucia Stefanini, Pierrette André, Timothy D. Ouellette, Michael P. Reilly, Steven E. McKenzie, Wolfgang Bergmeier

Blood (2011) 118 (4): 1113–1120.

https://doi.org/10.1182/blood-2011-03-342352

Published: 2011

Includes: Multimedia, Supplemental data

Journal Articles

PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model

Michael P. Reilly, Uma Sinha, Pierrette André, Scott M. Taylor, Yvonne Pak, Francis R. DeGuzman, Nisha Nanda, Anjali Pandey, Moritz Stolla, Wolfgang Bergmeier, Steven E. McKenzie

Blood (2011) 117 (7): 2241–2246.

https://doi.org/10.1182/blood-2010-03-274969

Published: 2011

Includes: Supplemental data

Journal Articles

Amelioration of murine immune thrombocytopenia by CD44 antibodies: a potential therapy for ITP?

Andrew R. Crow, Seng Song, Sara J. Suppa, Shuhua Ma, Michael P. Reilly, Pierrette Andre, Steven E. McKenzie, Alan H. Lazarus

Blood (2011) 117 (3): 971–974.

https://doi.org/10.1182/blood-2010-05-280115

Published: 2011

Includes: Supplemental data

Journal Articles

Critical Role of CalDAG-GEFI In FCγRIIa-Dependent Platelet Activation and Thrombosis

Moritz Stolla, MD, Lucia Stefanini, PhD, Timothy Daniel Ouellette, BS, Firdos Ahmad, PhD, Michael P Reilly, PhD, Steven McKenzie, MD, PhD, Wolfgang Bergmeier, PhD

Blood (2010) 116 (21): 3196.

https://doi.org/10.1182/blood.V116.21.3196.3196

Published: 2010

Journal Articles

The clot thickens (or not)

Steven E. McKenzie, Michael P. Reilly

Blood (2009) 114 (9): 1722–1723.

https://doi.org/10.1182/blood-2009-06-226720

Published: 2009

Journal Articles

PRT060318, a Novel Syk Inhibitor, Prevents Heparin-Induced Thrombocytopenia in a Transgenic Mouse Model

Michael P. Reilly, PhD, Uma Sinha, PhD, Pierrette Andre, Scott M. Taylor, MS, Yvonne Pak, PhD, Francis R. DeGuzman, Nisha Nanda, PhD, Anjali Pandey, PhD, Steven E. McKenzie, MD, PhD

Blood (2008) 112 (11): 269.

https://doi.org/10.1182/blood.V112.11.269.269

Published: 2008

Journal Articles

Signaling Pathways in HIT Immune Complex Stimulation of Monocyte Tissue Factor.

Steven E. McKenzie, MD, PhD, Diana L. Cassel, PhD, Peter Casasanto, MS, Scott M. Taylor, MS, Michael P. Reilly, PhD

Blood (2006) 108 (11): 95.

https://doi.org/10.1182/blood.V108.11.95.95

Published: 2006

Journal Articles

The Role of Fcγ Receptor Signaling, Tissue Factor Expression and Monocyte-Platelet Cross-Talk in the Initiation of Thrombosis by Immune Complexes.

Peter Casasanto, MS, Michael P. Reilly, PhD, Ming-Lin Liu, MD, PhD, Kevin Jon Williams, MD, Steven E. McKenzie, MD, PhD

Blood (2005) 106 (11): 2167.

https://doi.org/10.1182/blood.V106.11.2167.2167

Published: 2005

Journal Articles

A Human Antibody, Cloned from a Patient with Heparin-Induced Thrombocytopenia, That Binds Heparin/Platelet Factor 4 Complexes.

Scott K. Dessain, MD, PhD, Katherine E. Rybinski, Sharad P. Adekar, MD, Lubica Rauova, MD, PhD, Bruce S. Sachais, MD, PhD, Steven E. McKenzie, MD, PhD, Michael P. Reilly, PhD

Blood (2005) 106 (11): 58.

https://doi.org/10.1182/blood.V106.11.58.58

Published: 2005

Journal Articles

Dietary Hypercholesterolemia Enhances Heparin-Induced Thrombocytopenia/Thrombosis: A Prothrombotic Risk Factor in a Transgenic Mouse Model.

Michael P. Reilly, PhD, Scott K. Dessain, MD, PhD, Scott M. Taylor, MS, M. Anna Kowalska, PhD, Mortimer Poncz, MD, Bruce S. Sachais, MD, PhD, Douglas B. Cines, MD, Gowthami Arepally, MD, Kevin Jon Williams, MD, Steven E. McKenzie, MD, PhD

Blood (2005) 106 (11): 56.

https://doi.org/10.1182/blood.V106.11.56.56

Published: 2005

Journal Articles

PF4/heparin complexes are T cell–dependent antigens

Shayela Suvarna, Lubica Rauova, Emily K. E. McCracken, Christina M. Goss, Bruce S. Sachais, Steven E. McKenzie, Michael P. Reilly, Michael Dee Gunn, Douglas B. Cines, Mortimer Poncz, Gowthami Arepally

Blood (2005) 106 (3): 929–931.

https://doi.org/10.1182/blood-2004-12-4955

Published: 2005

Journal Articles

Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia

Lubica Rauova, Mortimer Poncz, Steven E. McKenzie, Michael P. Reilly, Gowthami Arepally, John W. Weisel, Chandrasekaran Nagaswami, Douglas B. Cines, Bruce S. Sachais

Blood (2005) 105 (1): 131–138.

https://doi.org/10.1182/blood-2004-04-1544

Published: 2005

Journal Articles

Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcγRIIA

Michael P. Reilly, Scott M. Taylor, Nealie K. Hartman, Gowthami M. Arepally, Bruce S. Sachais, Douglas B. Cines, Mortimer Poncz, Steven E. McKenzie

Blood (2001) 98 (8): 2442–2447.

https://doi.org/10.1182/blood.V98.8.2442

Published: 2001

Journal Articles

Localization of distal regulatory domains in the megakaryocyte-specific platelet basic protein/platelet factor 4 gene locus

Chunyan Zhang, Michael A. Thornton, M. Anna Kowalska, Bruce S. Sachis, Michael Feldman, Mortimer Poncz, Steven E. McKenzie, Michael P. Reilly

Blood (2001) 98 (3): 610–617.

https://doi.org/10.1182/blood.V98.3.610

Published: 2001

Journal Articles

Thrombosis and shock induced by activating antiplatelet antibodies in human FcγRIIA transgenic mice: the interplay among antibody, spleen, and Fc receptor

Scott M. Taylor, Michael P. Reilly, Alan D. Schreiber, Paul Chien, Joseph R. Tuckosh, Steven E. McKenzie

Blood (2000) 96 (13): 4254–4260.

https://doi.org/10.1182/blood.V96.13.4254

Published: 2000

Journal Articles

−245 bp of 5′-Flanking Region From the Human Platelet Factor 4 Gene Is Sufficient to Drive Megakaryocyte-Specific Expression In Vivo

Zheng Cui, Michael P. Reilly, Saul Surrey, Elias Schwartz, Steven E. McKenzie

Blood (1998) 91 (7): 2326–2333.

https://doi.org/10.1182/blood.V91.7.2326

Published: 1998

NARROW

CalDAG-GEFI deficiency protects mice in a novel model of FcγRIIA-mediated thrombosis and thrombocytopenia

PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model

Amelioration of murine immune thrombocytopenia by CD44 antibodies: a potential therapy for ITP?

Critical Role of CalDAG-GEFI In FCγRIIa-Dependent Platelet Activation and Thrombosis

The clot thickens (or not)

PRT060318, a Novel Syk Inhibitor, Prevents Heparin-Induced Thrombocytopenia in a Transgenic Mouse Model

Signaling Pathways in HIT Immune Complex Stimulation of Monocyte Tissue Factor.

The Role of Fcγ Receptor Signaling, Tissue Factor Expression and Monocyte-Platelet Cross-Talk in the Initiation of Thrombosis by Immune Complexes.

A Human Antibody, Cloned from a Patient with Heparin-Induced Thrombocytopenia, That Binds Heparin/Platelet Factor 4 Complexes.

Dietary Hypercholesterolemia Enhances Heparin-Induced Thrombocytopenia/Thrombosis: A Prothrombotic Risk Factor in a Transgenic Mouse Model.

PF4/heparin complexes are T cell–dependent antigens

Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcγRIIA

Localization of distal regulatory domains in the megakaryocyte-specific platelet basic protein/platelet factor 4 gene locus

Thrombosis and shock induced by activating antiplatelet antibodies in human FcγRIIA transgenic mice: the interplay among antibody, spleen, and Fc receptor

−245 bp of 5′-Flanking Region From the Human Platelet Factor 4 Gene Is Sufficient to Drive Megakaryocyte-Specific Expression In Vivo

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American Society of Hematology

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American Society of Hematology

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