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Journal Articles

Let’s “brake” it down

Lucia Stefanini

Blood (2020) 136 (15): 1703–1705.

https://doi.org/10.1182/blood.2020007350

Published: 2020

Journal Articles

Functional redundancy between RAP1 isoforms in murine platelet production and function

Lucia Stefanini, Robert H. Lee, David S. Paul, Ellen C. O'Shaughnessy, Dorsaf Ghalloussi, Christopher I. Jones, Yacine Boulaftali, Kathryn O. Poe, Raymond Piatt, Dan O. Kechele, Kathleen M. Caron, Klaus M. Hahn, Jonathan M. Gibbins, Wolfgang Bergmeier

Blood (2018) 132 (18): 1951–1962.

https://doi.org/10.1182/blood-2018-03-838714

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

Premature Platelet Activation and Resistance to P2Y12 Inhibitors in Rasa3 Mutant Mice

Wolfgang Bergmeier, PhD, David S Paul, PhD, Lucia Stefanini, PhD, Raymond F. Robledo, PhD, E. Ricky Chan, PhD, Todd M Getz, PhD, Raymond Piatt, Yacine Boulaftali, PhD, Mark D Adams, Luanne L. Peters, PhD

Blood (2014) 124 (21): 91.

https://doi.org/10.1182/blood.V124.21.91.91

Published: 2014

Journal Articles

A talin mutant that impairs talin-integrin binding in platelets decelerates αIIbβ3 activation without pathological bleeding

Lucia Stefanini, Feng Ye, Adam K. Snider, Kasra Sarabakhsh, Raymond Piatt, David S. Paul, Wolfgang Bergmeier, Brian G. Petrich

Blood (2014) 123 (17): 2722–2731.

https://doi.org/10.1182/blood-2013-12-543363

Published: 2014

Includes: Supplemental data

Journal Articles

CalDAG-GEFI deficiency protects mice in a novel model of FcγRIIA-mediated thrombosis and thrombocytopenia

Moritz Stolla, Lucia Stefanini, Pierrette André, Timothy D. Ouellette, Michael P. Reilly, Steven E. McKenzie, Wolfgang Bergmeier

Blood (2011) 118 (4): 1113–1120.

https://doi.org/10.1182/blood-2011-03-342352

Published: 2011

Includes: Multimedia, Supplemental data

Journal Articles

The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy

Moritz Stolla, Lucia Stefanini, R. Claire Roden, Massiel Chavez, Jessica Hirsch, Teshell Greene, Timothy D. Ouellette, Sean F. Maloney, Scott L. Diamond, Mortimer Poncz, Donna S. Woulfe, Wolfgang Bergmeier

Blood (2011) 117 (3): 1005–1013.

https://doi.org/10.1182/blood-2010-07-297713

Published: 2011

Includes: Multimedia, Supplemental data

Journal Articles

Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flow

Judith M. E. M. Cosemans, Saskia E. M. Schols, Lucia Stefanini, Susanne de Witt, Marion A. H. Feijge, Karly Hamulyák, Hans Deckmyn, Wolfgang Bergmeier, Johan W. M. Heemskerk

Blood (2011) 117 (2): 651–660.

https://doi.org/10.1182/blood-2010-01-262683

Published: 2011

Includes: Multimedia, Supplemental data

Journal Articles

Critical Role of CalDAG-GEFI In FCγRIIa-Dependent Platelet Activation and Thrombosis

Moritz Stolla, MD, Lucia Stefanini, PhD, Timothy Daniel Ouellette, BS, Firdos Ahmad, PhD, Michael P Reilly, PhD, Steven McKenzie, MD, PhD, Wolfgang Bergmeier, PhD

Blood (2010) 116 (21): 3196.

https://doi.org/10.1182/blood.V116.21.3196.3196

Published: 2010

Journal Articles

STIM1 Deficiency Results In Impaired Platelet Procoagulant Activity and Protection From Arterial Thrombosis

Firdos Ahmad, PhD, Lucia Stefanini, PhD, Timothy Daniel Ouellette, Teshell K Greene, B.S, Stefan Feske, MD, Wolfgang Bergmeier, PhD

Blood (2010) 116 (21): 485.

https://doi.org/10.1182/blood.V116.21.485.485

Published: 2010

Journal Articles

p38 mitogen-activated protein kinase activation during platelet storage: consequences for platelet recovery and hemostatic function in vivo

Matthias Canault, Daniel Duerschmied, Alexander Brill, Lucia Stefanini, Daphne Schatzberg, Stephen M. Cifuni, Wolfgang Bergmeier, Denisa D. Wagner

Blood (2010) 115 (9): 1835–1842.

https://doi.org/10.1182/blood-2009-03-211706

Published: 2010

Includes: Supplemental data

Journal Articles

Revised Model for Platelet Adhesion to Collagen.

Lucia Stefanini, PhD, Moritz Stolla, MD, Sean F Maloney, Timothy Daniel Ouellette, BS, Claire Roden, Scott L. Diamond, PhD, Wolfgang Bergmeier, PhD

Blood (2009) 114 (22): 2999.

https://doi.org/10.1182/blood.V114.22.2999.2999

Published: 2009

Journal Articles

The Signaling Molecule CalDAG-GEFI Represents a Novel Target for Antithrombotic Therapy.

Moritz Stolla, M.D., Lucia Stefanini, Ph.D., Jessica Hirsch, Claire Roden, Timothy Daniel Ouellette, BS, Mortimer Poncz, M.D., Wolfgang Bergmeier, Ph.D.

Blood (2009) 114 (22): 1077.

https://doi.org/10.1182/blood.V114.22.1077.1077

Published: 2009

Journal Articles

CalDAG-GEFI is at the nexus of calcium-dependent platelet activation

Lucia Stefanini, R. Claire Roden, Wolfgang Bergmeier

Blood (2009) 114 (12): 2506–2514.

https://doi.org/10.1182/blood-2009-04-218768

Published: 2009

Journal Articles

Genetic evidence for a predominant role of PI3Kβ catalytic activity in ITAM- and integrin-mediated signaling in platelets

Ilaria Canobbio, Lucia Stefanini, Lina Cipolla, Elisa Ciraolo, Cristian Gruppi, Cesare Balduini, Emilio Hirsch, Mauro Torti

Blood (2009) 114 (10): 2193–2196.

https://doi.org/10.1182/blood-2009-03-208074

Published: 2009

Includes: Supplemental data

Journal Articles

Role of CalDAG-GEFI in Calcium-Dependent Thromboxane A2 Generation

Lucia Stefanini, PhD, R. Claire Roden, Wolfgang Bergmeier, PhD

Blood (2008) 112 (11): 2852.

https://doi.org/10.1182/blood.V112.11.2852.2852

Published: 2008

Journal Articles

Genetic Evidence for a Predominant Role of PI3Kβ In ITAM— and Integrin-Mediated Signaling in Platelets

Ilaria Canobbio, Lucia Stefanini, Lina Cipolla, Elisa Ciraolo, Cristian Gruppi, Emilio Hirsch, Cesare Balduini, Mauro Torti, PhD

Blood (2008) 112 (11): 410.

https://doi.org/10.1182/blood.V112.11.410.410

Published: 2008

Journal Articles

Tyrosine Phosphorylation-Independent Activation of PLCγ2 Downstream Integrin α 2 β 1 in Platelets: A Possible Role for the Small GTPase Rac.

Gianni F. Guidetti, PhD, Bruno Bernardi, Lucia Stefanini, Francesca Campus, PhD, Cesare Balduini, MD, Mauro Torti, PhD

Blood (2006) 108 (11): 1532.

https://doi.org/10.1182/blood.V108.11.1532.1532

Published: 2006

Journal Articles

A New Role for FcγRIIA in the Potentiation of Human Platelet Activation Induced by Weak Stimulation.

Ilaria Canobbio, PhD, Lucia Stefanini, Gianni F. Guidetti, PhD, Cesare Balduini, MD, Mauro Torti, PhD

Blood (2005) 106 (11): 1648.

https://doi.org/10.1182/blood.V106.11.1648.1648

Published: 2005

NARROW

Let’s “brake” it down

Functional redundancy between RAP1 isoforms in murine platelet production and function

Premature Platelet Activation and Resistance to P2Y12 Inhibitors in Rasa3 Mutant Mice

A talin mutant that impairs talin-integrin binding in platelets decelerates αIIbβ3 activation without pathological bleeding

CalDAG-GEFI deficiency protects mice in a novel model of FcγRIIA-mediated thrombosis and thrombocytopenia

The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy

Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flow

Critical Role of CalDAG-GEFI In FCγRIIa-Dependent Platelet Activation and Thrombosis

STIM1 Deficiency Results In Impaired Platelet Procoagulant Activity and Protection From Arterial Thrombosis

p38 mitogen-activated protein kinase activation during platelet storage: consequences for platelet recovery and hemostatic function in vivo

Revised Model for Platelet Adhesion to Collagen.

The Signaling Molecule CalDAG-GEFI Represents a Novel Target for Antithrombotic Therapy.

CalDAG-GEFI is at the nexus of calcium-dependent platelet activation

Genetic evidence for a predominant role of PI3Kβ catalytic activity in ITAM- and integrin-mediated signaling in platelets

Role of CalDAG-GEFI in Calcium-Dependent Thromboxane A2 Generation

Genetic Evidence for a Predominant Role of PI3Kβ In ITAM— and Integrin-Mediated Signaling in Platelets

Tyrosine Phosphorylation-Independent Activation of PLCγ2 Downstream Integrin α 2 β 1 in Platelets: A Possible Role for the Small GTPase Rac.

A New Role for FcγRIIA in the Potentiation of Human Platelet Activation Induced by Weak Stimulation.

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American Society of Hematology

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American Society of Hematology

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