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Journal Articles

PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model

Michael P. Reilly, Uma Sinha, Pierrette André, Scott M. Taylor, Yvonne Pak, Francis R. DeGuzman, Nisha Nanda, Anjali Pandey, Moritz Stolla, Wolfgang Bergmeier, Steven E. McKenzie
Journal: Blood
Blood (2011) 117 (7): 2241–2246.
https://doi.org/10.1182/blood-2010-03-274969
Published: 2011
Includes: Supplemental data
Journal Articles

Specific Inhibition of Syk Suppresses Leukocyte Immune Function and Alleviates Inflammation In Rodent Models of Rheumatoid Arthritis

Greg Coffey, PhD, DeGuzman Francis, Ph.D., Mayuko Inagaki, Yvonne Pak, Suzanne Delaney, Andreas Betz, Zhaozhong J Jia, Qing Xu, Shawn Bauer, Yonghong Song, Anjali Pandey, PhD, Dale Baker, DVM, PhD, Stanley Hollenbach, David R. Phillips, PhD, Uma Sinha, PhD
Journal: Blood
Blood (2010) 116 (21): 1727.
https://doi.org/10.1182/blood.V116.21.1727.1727
Published: 2010
Journal Articles

PRT060318, a Novel Syk Inhibitor, Prevents Heparin-Induced Thrombocytopenia in a Transgenic Mouse Model

Michael P. Reilly, PhD, Uma Sinha, PhD, Pierrette Andre, Scott M. Taylor, MS, Yvonne Pak, PhD, Francis R. DeGuzman, Nisha Nanda, PhD, Anjali Pandey, PhD, Steven E. McKenzie, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 269.
https://doi.org/10.1182/blood.V112.11.269.269
Published: 2008
Journal Articles

Animal Models of Thrombosis Help Predict the Human Therapeutic Concentration of PRT54021, a Potent Oral Factor Xa Inhibitor.

Keith Abe, Gail Siu, Susan Edwards, Pei Hua Lin, Bing Yan Zhu, Ulla Marzec, Stephen Hanson, Yvonne Pak, Stanley Hollenbach, Uma Sinha
Journal: Blood
Blood (2006) 108 (11): 901.
https://doi.org/10.1182/blood.V108.11.901.901
Published: 2006
Journal Articles

Antithrombotic Activity of PRT54021, a Potent Oral Direct Factor Xa Inhibitor, Can Be Monitored Using a Novel Prothrombinase Inhibition Bioassay.

Uma Sinha, PhD, Susan T. Edwards, MS, Paul W. Wong, BS, Suzanne M. Delaney, PhD, Nisha Nanda, PhD, Ulla M. Marzec, MS, Yvonne Pak, PhD, Stanley J. Hollenbach, JD, Stephen R. Hanson, PhD
Journal: Blood
Blood (2006) 108 (11): 907.
https://doi.org/10.1182/blood.V108.11.907.907
Published: 2006