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INSIDE BLOOD

Hemangioblasts in adults?

Margaret H. Baron

View Articletitled, Hemangioblasts in adults?

Light at the end of the VOD tunnel?

Thomas C. Shea,Scott I. Bearman

View Articletitled, Light at the end of the VOD tunnel?

Surrogate markers for lysosomal storage

Mario A. Cabrera-Salazar,John A. Barranger

View Articletitled, Surrogate markers for lysosomal storage

Hard time for anergic cytotoxic T cells

Dieter Kabelitz

View Articletitled, Hard time for anergic cytotoxic T cells

Early gastrointestinal GvHD: apoptosis but no donor repair?

Ernst Holler

View Articletitled, Early gastrointestinal GvHD: apoptosis but no donor repair?

Overcoming imatinib resistance

Ravi Bhatia

View Articletitled, Overcoming imatinib resistance

Hemophilia gene therapy: it's a matter of expression

David Lillicrap

View Articletitled, Hemophilia gene therapy: it's a matter of expression

MLL—a gene of interest

Diane C. Arthur

View Articletitled, MLL—a gene of interest

Hidden identity of Hodgkin/Reed-Sternberg cells

Marshall E. Kadin,Christopher Carpenter

View Articletitled, Hidden identity of Hodgkin/Reed-Sternberg cells

Hopes for kinase inhibitors active against AML take FLT

Scott H. Kaufmann

View Articletitled, Hopes for kinase inhibitors active against AML take FLT

Major questions after “minor” answers

Alois Gratwohl

View Articletitled, Major questions after “minor” answers

Myeloma is on the move

John D. Shaughnessy, Jr

View Articletitled, Myeloma is on the move

BLOOD WORK

Hereditary spherocytosis

View Articletitled, Hereditary spherocytosis

PLENARY PAPERS

Transplanted adult hematopoietic stems cells differentiate into functional endothelial cells

Alexis S. Bailey,Shuguang Jiang,Michael Afentoulis,Christina I. Baumann,David A. Schroeder,Susan B. Olson,Melissa H. Wong,William H. Fleming

View Articletitled, Transplanted adult hematopoietic stems cells differentiate into functional endothelial cells

REVIEW ARTICLES

Treatment of multiple myeloma

Bart Barlogie,John Shaughnessy,Guido Tricot,Joth Jacobson,Maurizio Zangari,Elias Anaissie,Ron Walker,John Crowley

View Articletitled, Treatment of multiple myeloma

CHEMOKINES

Marked elevation of the chemokine CCL18/PARC in Gaucher disease: a novel surrogate marker for assessing therapeutic intervention
Clinical Trials & Observations

Rolf G. Boot,Marri Verhoek,Maaike de Fost,Carla E. M. Hollak,Mario Maas,Boris Bleijlevens,Marielle J. van Breemen,Marjan van Meurs,Leonie A. Boven,Jon D. Laman,Mary Teresa Moran,Timothy M. Cox,Johannes M. F. G. Aerts

View Articletitled, Marked elevation of the chemokine CCL18/PARC in Gaucher disease: a novel surrogate marker for assessing therapeutic intervention

CCL16 activates an angiogenic program in vascular endothelial cells

Marina Strasly,Gabriella Doronzo,Paola Capello,Donatella Valdembri,Marco Arese,Stefania Mitola,Paul Moore,Giulio Alessandri,Mirella Giovarelli,Federico Bussolino

View Articletitled, CCL16 activates an angiogenic program in vascular endothelial cells

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Prognostic value of apoptotic cells and infiltrating neutrophils in graft-versus-host disease of the gastrointestinal tract in humans: TNF and Fas expression
Clinical Trials & Observations

Gérard Socié,Jean-Yves Mary,Marc Lemann,Marjan Daneshpouy,Philippe Guardiola,Véronique Meignin,Lionel Ades,Hélène Esperou,Patricia Ribaud,Agnès Devergie,Eliane Gluckman,Jean-Claude Ameisen,Anne Janin

View Articletitled, Prognostic value of apoptotic cells and infiltrating neutrophils in graft-versus-host disease of the gastrointestinal tract in humans: TNF and Fas expression

Three cycles of adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) or epirubicin, bleomycin, vinblastine, and methotrexate (EBVM) plus extended field radiation therapy in early and intermediate Hodgkin disease: 10-year results of a randomized trial
Clinical Trials & Observations

Christine le Maignan,Bernard Desablens,Vincent Delwail,Mahmoud Dib,Christian Berthou,Magda Vigier,Christiane Ghandour,Saïd Atmani,Philippe Casassus,Hervé Maisonneuve,Annick Le Mevel,Catherine Traullé,Marc Bernard,Josette Brière,Pierre Colonna,Jean-Marie Andrieu

View Articletitled, Three cycles of adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) or epirubicin, bleomycin, vinblastine, and methotrexate (EBVM) plus extended field radiation therapy in early and intermediate Hodgkin disease: 10-year results of a randomized trial

Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia
Clinical Trials & Observations

Shinji Kishi,Wenjian Yang,Benoit Boureau,Stanislas Morand,Soma Das,Peixian Chen,Edwin H. Cook,Gary L. Rosner,Erin Schuetz,Ching-Hon Pui,Mary V. Relling

View Articletitled, Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia

Supplemental data

Acute graft-versus-host disease in patients with Fanconi anemia or acquired aplastic anemia undergoing bone marrow transplantation from HLA-identical sibling donors: risk factors and influence on outcome
Clinical Trials & Observations

Philippe Guardiola,Gérard Socié,Xiaxin Li,Patricia Ribaud,Agnès Devergie,Hélène Espérou,Patrice Richard,Richard Traineau,Anne Janin,Eliane Gluckman

View Articletitled, Acute graft-versus-host disease in patients with Fanconi anemia or acquired aplastic anemia undergoing bone marrow transplantation from HLA-identical sibling donors: risk factors and influence on outcome

Hepatic injury after nonmyeloablative conditioning followed by allogeneic hematopoietic cell transplantation: a study of 193 patients
Clinical Trials & Observations

William J. Hogan,Michael Maris,Barry Storer,Brenda M. Sandmaier,David G. Maloney,H. Gary Schoch,Ann E. Woolfrey,Howard M. Shulman,Rainer Storb,George B. McDonald

View Articletitled, Hepatic injury after nonmyeloablative conditioning followed by allogeneic hematopoietic cell transplantation: a study of 193 patients

GENE THERAPY

Safety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1

Valder R. Arruda,Joerg Schuettrumpf,Roland W. Herzog,Timothy C. Nichols,Nancy Robinson,Yasmin Lotfi,Federico Mingozzi,Weidong Xiao,Linda B. Couto,Katherine A. High

View Articletitled, Safety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1

Protection from endotoxemia by adenoviral-mediated gene transfer of human bactericidal/permeability-increasing protein

Scott Alexander,Jonathan Bramson,Ronan Foley,Zhou Xing

View Articletitled, Protection from endotoxemia by adenoviral-mediated gene transfer of human bactericidal/permeability-increasing protein

HEMATOPOIESIS

Ephrin receptor, EphB4, regulates ES cell differentiation of primitive mammalian hemangioblasts, blood, cardiomyocytes, and blood vessels

Zhengyu Wang,Kenneth Cohen,Ying Shao,Pamela Mole,David Dombkowski,David T. Scadden

View Articletitled, Ephrin receptor, EphB4, regulates ES cell differentiation of primitive mammalian hemangioblasts, blood, cardiomyocytes, and blood vessels

Neutrophil-derived MMP-9 mediates synergistic mobilization of hematopoietic stem and progenitor cells by the combination of G-CSF and the chemokines GROβ/CXCL2 and GROβ_T /CXCL2_Δ4

Louis M. Pelus,Huimin Bian,Andrew G. King,Seiji Fukuda

View Articletitled, Neutrophil-derived MMP-9 mediates synergistic mobilization of hematopoietic stem and progenitor cells by the combination of G-CSF and the chemokines GROβ/CXCL2 and GROβT /CXCL2Δ4

Survivin regulates hematopoietic progenitor cell proliferation through p21^WAF1/Cip1-dependent and -independent pathways

Seiji Fukuda,Charlie R. Mantel,Louis M. Pelus

View Articletitled, Survivin regulates hematopoietic progenitor cell proliferation through p21WAF1/Cip1-dependent and -independent pathways

Jun N-terminal kinase activity and early growth-response factor-1 gene expression are down-regulated in Fanconi anemia group A lymphoblasts

Carlos Pipaon,Jose Antonio Casado,Juan Antonio Bueren,Jose Luis Fernandez-Luna

View Articletitled, Jun N-terminal kinase activity and early growth-response factor-1 gene expression are down-regulated in Fanconi anemia group A lymphoblasts

Adult human hematopoietic cells provide functional hemangioblast activity
Brief Report

Christopher R. Cogle,David A. Wainman,Marda L. Jorgensen,Steven M. Guthrie,Robert N. Mames,Edward W. Scott

View Articletitled, Adult human hematopoietic cells provide functional hemangioblast activity

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Enhanced in vivo platelet adhesion in vasodilator-stimulated phosphoprotein (VASP)–deficient mice

Steffen Massberg,Sabine Grüner,Ildiko Konrad,Maisa I. Garcia Arguinzonis,Martin Eigenthaler,Kathrin Hemler,Julia Kersting,Christian Schulz,Iris Müller,Felicitas Besta,Bernhard Nieswandt,Ulrich Heinzmann,Ulrich Walter,Meinrad Gawaz

View Articletitled, Enhanced in vivo platelet adhesion in vasodilator-stimulated phosphoprotein (VASP)–deficient mice

Neonatal gene transfer with a retroviral vector results in tolerance to human factor IX in mice and dogs

Jun Zhang,Lingfei Xu,Mark E. Haskins,Katherine Parker Ponder

View Articletitled, Neonatal gene transfer with a retroviral vector results in tolerance to human factor IX in mice and dogs

Combined deficiency of protease-activated receptor-4 and fibrinogen recapitulates the hemostatic defect but not the embryonic lethality of prothrombin deficiency

Eric Camerer,Daniel N. Duong,Justin R. Hamilton,Shaun R. Coughlin

View Articletitled, Combined deficiency of protease-activated receptor-4 and fibrinogen recapitulates the hemostatic defect but not the embryonic lethality of prothrombin deficiency

Deletion of alanine 2201 in the FVIII C2 domain results in mild hemophilia A by impairing FVIII binding to VWF and phospholipids and destroys a major FVIII antigenic determinant involved in inhibitor development
Clinical Trials & Observations Brief Report

Roseline d'Oiron,Jean-Maurice Lavergne,Renaud Lavend'homme,Abdellah Benhida,Jean-Claude Bordet,Claude Negrier,Kathelijne Peerlinck,Jos Vermylen,Jean-Marie Saint-Remy,Marc Jacquemin

View Articletitled, Deletion of alanine 2201 in the FVIII C2 domain results in mild hemophilia A by impairing FVIII binding to VWF and phospholipids and destroys a major FVIII antigenic determinant involved in inhibitor development

Selective inactivation of p27^Kip1 in hematopoietic progenitor cells increases neointimal macrophage proliferation and accelerates atherosclerosis
Brief Report

Antonio Díez-Juan,Paloma Pérez,Miguel Aracil,David Sancho,Antonio Bernad,Francisco Sánchez-Madrid,Vicente Andrés

View Articletitled, Selective inactivation of p27Kip1 in hematopoietic progenitor cells increases neointimal macrophage proliferation and accelerates atherosclerosis

IMMUNOBIOLOGY

Integration of apoptosis and telomere erosion in virus-specific CD8⁺ T cells from blood and tonsils during primary infection

Maria Vieira D. Soares,Fiona J. Plunkett,Caroline S. Verbeke,Joanne E. Cook,Jeff M. Faint,Lavina L. Belaramani,Jean M. Fletcher,Nicholas Hammerschmitt,Malcolm Rustin,Wolfgang Bergler,Peter C. L. Beverley,Mike Salmon,Arne N. Akbar

View Articletitled, Integration of apoptosis and telomere erosion in virus-specific CD8+ T cells from blood and tonsils during primary infection

Bcl-x_L antagonism of BCR-coupled mitochondrial phospholipase A₂ signaling correlates with protection from apoptosis in WEHI-231 B cells

Elad Katz,Caroline Lord,Catriona A. Ford,Stephen B. Gauld,Natalie A. Carter,Margaret M. Harnett

View Articletitled, Bcl-xL antagonism of BCR-coupled mitochondrial phospholipase A2 signaling correlates with protection from apoptosis in WEHI-231 B cells

Ligation of CD137 receptor prevents and reverses established anergy of CD8⁺ cytolytic T lymphocytes in vivo

Ryan A. Wilcox,Koji Tamada,Dallas B. Flies,Gefeng Zhu,Andrei I. Chapoval,Bruce R. Blazar,W. Martin Kast,Lieping Chen

View Articletitled, Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo

Female agammaglobulinemia due to the Bruton tyrosine kinase deficiency caused by extremely skewed X-chromosome inactivation
Clinical Trials & Observations Brief Report

Hidetoshi Takada,Hirokazu Kanegane,Akihiko Nomura,Ken Yamamoto,Kenji Ihara,Yasuhiko Takahashi,Satoshi Tsukada,Toshio Miyawaki,Toshiro Hara

View Articletitled, Female agammaglobulinemia due to the Bruton tyrosine kinase deficiency caused by extremely skewed X-chromosome inactivation

NEOPLASIA

Expression of intracellular signaling molecules in classical and lymphocyte predominance Hodgkin disease

Teresa Marafioti,Michela Pozzobon,Martin-Leo Hansmann,Georges Delsol,Stefano A. Pileri,David Y. Mason

View Articletitled, Expression of intracellular signaling molecules in classical and lymphocyte predominance Hodgkin disease

ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis

Enrico Garattini,Edoardo Parrella,Luisa Diomede,Maurizio Gianni',Yesim Kalac,Lucio Merlini,Daniele Simoni,Romina Zanier,Fabiana Fosca Ferrara,Ilaria Chiarucci,Paolo Carminati,Mineko Terao,Claudio Pisano

View Articletitled, ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis

In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl–positive cell lines

Paul La Rosée,Kara Johnson,Amie S. Corbin,Eric P. Stoffregen,Erika M. Moseson,Stephanie Willis,Michael M. Mauro,Junia V. Melo,Michael W. Deininger,Brian J. Druker

View Articletitled, In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl–positive cell lines

Primary nasal natural killer cell lymphoma: long-term treatment outcome and relationship with the International Prognostic Index
Clinical Trials & Observations

Chor-Sang Chim,Shing-Yan Ma,Wing-Yan Au,Carolyn Choy,Albert K. W. Lie,Raymond Liang,Chun-Chung Yau,Yok-Lam Kwong

View Articletitled, Primary nasal natural killer cell lymphoma: long-term treatment outcome and relationship with the International Prognostic Index

Transcriptional coactivation of c-Jun by the KSHV-encoded LANA

Jiabin An,Yiping Sun,Matthew B. Rettig

View Articletitled, Transcriptional coactivation of c-Jun by the KSHV-encoded LANA

Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies

Bruce Poppe,Jo Vandesompele,Claudia Schoch,Charlotta Lindvall,Krzysztof Mrózek,Clara D. Bloomfield,H. Berna Beverloo,Lucienne Michaux,Nicole Dastugue,Christian Herens,Nurten Yigit,Anne De Paepe,Anne Hagemeijer,Frank Speleman

View Articletitled, Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies

Th1, Th2, and activated T-cell marker and clinical prognosis in peripheral T-cell lymphoma, unspecified: comparison with AILD, ALCL, lymphoblastic lymphoma, and ATLL
Clinical Trials & Observations

Takeshi Tsuchiya,Koichi Ohshima,Kennosuke Karube,Takahiro Yamaguchi,Hiroaki Suefuji,Makoto Hamasaki,Chika Kawasaki,Junji Suzumiya,Masao Tomonaga,Masahiro Kikuchi

View Articletitled, Th1, Th2, and activated T-cell marker and clinical prognosis in peripheral T-cell lymphoma, unspecified: comparison with AILD, ALCL, lymphoblastic lymphoma, and ATLL

Interleukin-6–dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family–independent survival pathway closely associated with Stat3 activation

Katja Brocke-Heidrich,Antje K. Kretzschmar,Gabriele Pfeifer,Christian Henze,Dennis Löffler,Dirk Koczan,Hans-Jürgen Thiesen,Renate Burger,Martin Gramatzki,Friedemann Horn

View Articletitled, Interleukin-6–dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family–independent survival pathway closely associated with Stat3 activation

Supplemental data

Role of MTHFR genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia

Maja Krajinovic,Stéphanie Lamothe,Damian Labuda,Émilie Lemieux-Blanchard,Yves Théorêt,Albert Moghrabi,Daniel Sinnett

View Articletitled, Role of MTHFR genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia

Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma

Eunice S. Wang,Kaida Wu,Allison C. Chin,Selina Chen-Kiang,Krisztina Pongracz,Sergei Gryaznov,Malcolm A. S. Moore

View Articletitled, Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma

FLT3 ligand causes autocrine signaling in acute myeloid leukemia cells

Rui Zheng,Mark Levis,Obdulio Piloto,Patrick Brown,Brenda R. Baldwin,Norbert C. Gorin,Miloslav Beran,Zhenping Zhu,Dale Ludwig,Dan Hicklin,Larry Witte,Yiwen Li,Donald Small

View Articletitled, FLT3 ligand causes autocrine signaling in acute myeloid leukemia cells

Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray

View Articletitled, Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray

Identification and characterization of polymorphic variations of the ataxia telangiectasia mutated (ATM) gene in childhood Hodgkin disease

Masatoshi Takagi,Rika Tsuchida,Kaoru Oguchi,Teruko Shigeta,Shinichiro Nakada,Kimiko Shimizu,Misao Ohki,Domenico Delia,Luciana Chessa,Yoichi Taya,Makoto Nakanishi,Yukiko Tsunematsu,Fumio Bessho,Keiichi Isoyama,Yoshiki Hayashi,Kazuko Kudo,Jun Okamura,Shuki Mizutani

View Articletitled, Identification and characterization of polymorphic variations of the ataxia telangiectasia mutated (ATM) gene in childhood Hodgkin disease

Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses

Tatjana Stankovic,Mike Hubank,Debbie Cronin,Grant S. Stewart,Danielle Fletcher,Colin R. Bignell,Azra J. Alvi,Belinda Austen,Victoria J. Weston,Christopher Fegan,Philip J. Byrd,Paul A. H. Moss,A. Malcolm R. Taylor

View Articletitled, Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses

Insulin-like growth factor I induces migration and invasion of human multiple myeloma cells

Ya-Wei Qiang,Lei Yao,Giovanna Tosato,Stuart Rudikoff

View Articletitled, Insulin-like growth factor I induces migration and invasion of human multiple myeloma cells

FOP-FGFR1 tyrosine kinase, the product of a t(6;8) translocation, induces a fatal myeloproliferative disease in mice
Brief Report

Géraldine Guasch,Bénédicte Delaval,Christine Arnoulet,Min-Jue Xie,Luc Xerri,Danielle Sainty,Daniel Birnbaum,Marie-Josèphe Pébusque

View Articletitled, FOP-FGFR1 tyrosine kinase, the product of a t(6;8) translocation, induces a fatal myeloproliferative disease in mice

Infection of HHV-8⁺ primary effusion lymphoma cells with a recombinant Epstein-Barr virus leads to restricted EBV latency, altered phenotype, and increased tumorigenicity without affecting TCL1 expression
Brief Report

Pankaj Trivedi,Kumi Takazawa,Claudia Zompetta,Laura Cuomo,Elena Anastasiadou,Antonino Carbone,Stefania Uccini,Filippo Belardelli,Kenzo Takada,Luigi Frati,Alberto Faggioni

View Articletitled, Infection of HHV-8+ primary effusion lymphoma cells with a recombinant Epstein-Barr virus leads to restricted EBV latency, altered phenotype, and increased tumorigenicity without affecting TCL1 expression

PHAGOCYTES

Annexin II mediates plasminogen-dependent matrix invasion by human monocytes: enhanced expression by macrophages

Carrie Brownstein,Arunkumar B. Deora,Andrew T. Jacovina,Rebecca Weintraub,Menard Gertler,K. M. Faisal Khan,Domenick J. Falcone,Katherine A. Hajjar

View Articletitled, Annexin II mediates plasminogen-dependent matrix invasion by human monocytes: enhanced expression by macrophages

RED CELLS

Gene expression profiling in CD34 cells to identify differences between aplastic anemia patients and healthy volunteers

Weihua Zeng,Guibin Chen,Sachiko Kajigaya,Olga Nunez,Alexandra Charrow,Eric M. Billings,Neal S. Young

View Articletitled, Gene expression profiling in CD34 cells to identify differences between aplastic anemia patients and healthy volunteers

TRANSFUSION MEDICINE

Universal prestorage leukoreduction in Canada decreases platelet alloimmunization and refractoriness
Clinical Trials & Observations

Matthew D. Seftel,Gershon H. Growe,Tanya Petraszko,W. Barrett Benny,Alan Le,Chao-Yong Lee,John J. Spinelli,Heather J. Sutherland,Peter Tsang,Donna E. Hogge

View Articletitled, Universal prestorage leukoreduction in Canada decreases platelet alloimmunization and refractoriness

TRANSPLANTATION

Reduced stem cell mobilization in mice receiving antibiotic modulation of the intestinal flora: involvement of endotoxins as cofactors in mobilization

Gerjo A. Velders,Ronald van Os,Henny Hagoort,Perry Verzaal,Henri F. L. Guiot,Ivan J. D. Lindley,Roel Willemze,Ghislain Opdenakker,Willem E. Fibbe

View Articletitled, Reduced stem cell mobilization in mice receiving antibiotic modulation of the intestinal flora: involvement of endotoxins as cofactors in mobilization

Female donors contribute to a selective graft-versus-leukemia effect in male recipients of HLA-matched, related hematopoietic stem cell transplants
Clinical Trials & Observations

Sophia S. B. Randolph,Theodore A. Gooley,Edus H. Warren,Frederick R. Appelbaum,Stanley R. Riddell

View Articletitled, Female donors contribute to a selective graft-versus-leukemia effect in male recipients of HLA-matched, related hematopoietic stem cell transplants

Antibody response to DBY minor histocompatibility antigen is induced after allogeneic stem cell transplantation and in healthy female donors

David B. Miklos,Haesook T. Kim,Emmanuel Zorn,Ephraim P. Hochberg,Luxuan Guo,Alex Mattes-Ritz,Sebastien Viatte,Robert J. Soiffer,Joseph H. Antin,Jerome Ritz

View Articletitled, Antibody response to DBY minor histocompatibility antigen is induced after allogeneic stem cell transplantation and in healthy female donors

Little evidence of donor-derived epithelial cells in early digestive acute graft-versus-host disease
Brief Report

Véronique Meignin,Jean Soulier,Frédéric Brau,Marc Lemann,Eliane Gluckman,Anne Janin,Gérard Socié

View Articletitled, Little evidence of donor-derived epithelial cells in early digestive acute graft-versus-host disease

Impact of frontline fludarabine and cyclophosphamide combined treatment on peripheral blood stem cell mobilization in B-cell chronic lymphocytic leukemia
Clinical Trials & Observations Brief Report

Olivier Tournilhac,Bruno Cazin,Stéphane Leprètre,Marine Diviné,Karim Maloum,Alain Delmer,Bernard Grosbois,Pierre Feugier,Frederic Maloisel,Florence Villard,Bruno Villemagne,Dominique Bastit,Karim Belhadj,Nabi Azar,Mauricette Michallet,Geraud Manhès,Philippe Travade

View Articletitled, Impact of frontline fludarabine and cyclophosphamide combined treatment on peripheral blood stem cell mobilization in B-cell chronic lymphocytic leukemia

CORRESPONDENCE

Fetal origin of the GATA1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome

Akira Shimada,Gang Xu,Tsutomu Toki,Hirokazu Kimura,Yasuhide Hayashi,Etsuro Ito

View Articletitled, Fetal origin of the GATA1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome

Issue Archive

Table of Contents

INSIDE BLOOD

BLOOD WORK

PLENARY PAPERS

REVIEW ARTICLES

CHEMOKINES

Marked elevation of the chemokine CCL18/PARC in Gaucher disease: a novel surrogate marker for assessing therapeutic intervention Clinical Trials & Observations

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Prognostic value of apoptotic cells and infiltrating neutrophils in graft-versus-host disease of the gastrointestinal tract in humans: TNF and Fas expression Clinical Trials & Observations

Three cycles of adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) or epirubicin, bleomycin, vinblastine, and methotrexate (EBVM) plus extended field radiation therapy in early and intermediate Hodgkin disease: 10-year results of a randomized trial Clinical Trials & Observations

Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia Clinical Trials & Observations

Acute graft-versus-host disease in patients with Fanconi anemia or acquired aplastic anemia undergoing bone marrow transplantation from HLA-identical sibling donors: risk factors and influence on outcome Clinical Trials & Observations

Hepatic injury after nonmyeloablative conditioning followed by allogeneic hematopoietic cell transplantation: a study of 193 patients Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS

Adult human hematopoietic cells provide functional hemangioblast activity Brief Report

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Deletion of alanine 2201 in the FVIII C2 domain results in mild hemophilia A by impairing FVIII binding to VWF and phospholipids and destroys a major FVIII antigenic determinant involved in inhibitor development Clinical Trials & Observations Brief Report

Selective inactivation of p27Kip1 in hematopoietic progenitor cells increases neointimal macrophage proliferation and accelerates atherosclerosis Brief Report

IMMUNOBIOLOGY

Female agammaglobulinemia due to the Bruton tyrosine kinase deficiency caused by extremely skewed X-chromosome inactivation Clinical Trials & Observations Brief Report

NEOPLASIA

Primary nasal natural killer cell lymphoma: long-term treatment outcome and relationship with the International Prognostic Index Clinical Trials & Observations

Th1, Th2, and activated T-cell marker and clinical prognosis in peripheral T-cell lymphoma, unspecified: comparison with AILD, ALCL, lymphoblastic lymphoma, and ATLL Clinical Trials & Observations

FOP-FGFR1 tyrosine kinase, the product of a t(6;8) translocation, induces a fatal myeloproliferative disease in mice Brief Report

Infection of HHV-8+ primary effusion lymphoma cells with a recombinant Epstein-Barr virus leads to restricted EBV latency, altered phenotype, and increased tumorigenicity without affecting TCL1 expression Brief Report