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Journal Articles

Programmed Death-1 Homolog (PD-1H/VISTA) Blockade Confers a Synergistic Anti-Leukemia Effect with PD-1 Blockade

Tae Kon Kim, Xue Han, Qianni Hu, Carly Hedgepath, Junshik Hong, Jihyun Park, Emily F Mason, Lieping Chen

Blood (2022) 140 (Supplement 1): 87–88.

https://doi.org/10.1182/blood-2022-158314

Published: 2022

Journal Articles

PD-1H (VISTA) Induces Immune Evasion in Acute Myeloid Leukemia

Tae Kon Kim, MD PhD, Xue Han, PhD, Jun Wang, PhD, Miguel Sanmamed, MD, Tianxiang Zhang, PhD, Stephanie Halene, MD PhD, Manoj M Pillai, MD, Jun Lu, PhD, Mina Xu, MD, Amer M. Zeidan, MD, Steven D. Gore, MD, Madhav V Dhodapkar, MBBS, Lieping Chen, MD PhD

Blood (2017) 130 (Supplement 1): 2658.

https://doi.org/10.1182/blood.V130.Suppl_1.2658.2658

Published: 2017

Journal Articles

B7H1/B7.1 Interaction Alleviate Acute Gvhd in a PD-1 Dependent Manner

Ruishu Deng, MDPhD, Kaniel Cassady, Xiaofan Li, MDPhD, Sheng Yao, PhD, Mingfeng Zhang, PhD, Jeremy Racine, PhD, Jeffrey Lin, Lieping Chen, MDPhD, Defu Zeng, MD

Blood (2014) 124 (21): 2423.

https://doi.org/10.1182/blood.V124.21.2423.2423

Published: 2014

Journal Articles

Host Tissue PD-1 Pathway Contribute To Murine Chronic Graft-Versus-Host Disease Via Th1+Th17+ Cells

Hideaki Fujiwara, Yoshinobu Maeda, M.D., Ph.D., Koichiro Kobayashi, Hisakazu Nishimori, Ken-ichi Matsuoka, MD, PhD, Miyuki Azuma, MD, PhD, Hideo Yagita, PhD, Lieping Chen, MD, PhD, Mitsune Tanimoto, MD, PhD

Blood (2013) 122 (21): 3244.

https://doi.org/10.1182/blood.V122.21.3244.3244

Published: 2013

Journal Articles

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells

Eric F. Tewalt, Jarish N. Cohen, Sherin J. Rouhani, Cynthia J. Guidi, Hui Qiao, Shawn P. Fahl, Mark R. Conaway, Timothy P. Bender, Kenneth S. Tung, Anthony T. Vella, Adam J. Adler, Lieping Chen, Victor H. Engelhard

Blood (2012) 120 (24): 4772–4782.

https://doi.org/10.1182/blood-2012-04-427013

Published: 2012

Includes: Supplemental data

Journal Articles

Tissue Parenchymal Cell Expression of B7-H1 Inhibits Infiltrating T Cell Expansion and Prevents Persistence of Graft-Versus-Host Disease

Xiaofan Li, MD, Wei He, MD, Ruishu Deng, MD, Can Liu, MD, Miao Wang, MD, James Young, Lieping Chen, MD, PhD, Yuan-Zhong Chen, MD, Paul J Martin, MD, Stephen Forman, MD, Defu Zeng, MD

Blood (2011) 118 (21): 2974.

https://doi.org/10.1182/blood.V118.21.2974.2974

Published: 2011

Journal Articles

B7-H1 Molecules on Myeloma Cells Induce Aggressive Cell Behavior

Hideto Tamura, MD, PhD, Mariko Ishibashi, PhD, Taishi Yamashita, PhD, Asaka Kondo, MD, PhD, Namiko Okuyama, MD, Hideya Hyodo, MD, PhD, Yasuko Hamada, MD, Kazuo Dan, MD, PhD, Lieping Chen, MD, PhD, Kiyoyuki Ogata

Blood (2011) 118 (21): 474.

https://doi.org/10.1182/blood.V118.21.474.474

Published: 2011

Journal Articles

CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies

Holbrook E. Kohrt, Roch Houot, Matthew J. Goldstein, Kipp Weiskopf, Ash A. Alizadeh, Josh Brody, Antonia Müller, Russell Pachynski, Debra Czerwinski, Steven Coutre, Mark P. Chao, Lieping Chen, Thomas F. Tedder, Ronald Levy

Blood (2011) 117 (8): 2423–2432.

https://doi.org/10.1182/blood-2010-08-301945

Published: 2011

Includes: Supplemental data

Journal Articles

Immunomodulation of NK Cells through 4-1BB (CD137) to Improve the Anti-Lymphoma Activity of Rituximab: Antibody-Based Anti-Lymphoma Synergy

Holbrook E Kohrt, MD, Roch Houot, MD/PhD, Matthew J Goldstein, MD, Kipp Weiskopf, MD, Mark Chao, MD, Lieping Chen, MD/PhD, Thomas Tedder, PhD, Ron Levy, MD

Blood (2010) 116 (21): 422.

https://doi.org/10.1182/blood.V116.21.422.422

Published: 2010

Journal Articles

Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4 + Foxp3 + regulatory T cells in the establishment of oral tolerance

Tomohiro Fukaya, Hideaki Takagi, Yumiko Sato, Kaori Sato, Kawori Eizumi, Honami Taya, Tahiro Shin, Lieping Chen, Chen Dong, Miyuki Azuma, Hideo Yagita, Bernard Malissen, Katsuaki Sato

Blood (2010) 116 (13): 2266–2276.

https://doi.org/10.1182/blood-2009-10-250472

Published: 2010

Includes: Supplemental data

Journal Articles

B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance

Jang-June Park, Ryusuke Omiya, Yumiko Matsumura, Yukimi Sakoda, Atsuo Kuramasu, Mathew M. Augustine, Sheng Yao, Fumihiko Tsushima, Hidehiko Narazaki, Sudarshan Anand, Yingjia Liu, Scott E. Strome, Lieping Chen, Koji Tamada

Blood (2010) 116 (8): 1291–1298.

https://doi.org/10.1182/blood-2010-01-265975

Published: 2010

Includes: Supplemental data

Journal Articles

Interferon-γ and tumor necrosis factor-α induce an immunoinhibitory molecule, B7-H1, via nuclear factor-κB activation in blasts in myelodysplastic syndromes

Asaka Kondo, Taishi Yamashita, Hideto Tamura, Wanhong Zhao, Takashi Tsuji, Masumi Shimizu, Eiji Shinya, Hidemi Takahashi, Koji Tamada, Lieping Chen, Kazuo Dan, Kiyoyuki Ogata

Blood (2010) 116 (7): 1124–1131.

https://doi.org/10.1182/blood-2009-12-255125

Published: 2010

Includes: Supplemental data

Journal Articles

CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells

Hidehiko Narazaki, Yuwen Zhu, Liqun Luo, Gefeng Zhu, Lieping Chen

Blood (2010) 115 (10): 1941–1948.

https://doi.org/10.1182/blood-2008-12-192591

Published: 2010

Includes: Supplemental data

Journal Articles

Therapeutic Potential of Anti-CD137 Antibody in Lymphoma.

Roch Houot, MD, Matthew J Goldstein, Holbrook E Kohrt, MD, June H Myklebust, PhD, Ash A Alizadeh, MD, PhD, Jack T Lin, PhD, Jonathan M Irish, PhD, James A Torchia, Arne Kolstad, MD, PhD, Lieping Chen, MD, PhD, Ronald Levy, MD

Blood (2009) 114 (22): 722.

https://doi.org/10.1182/blood.V114.22.722.722

Published: 2009

Journal Articles

Interferon-γ and Tumor Necrosis Factor-α Induce An Immunoinhibitory Molecule, B7-H1, Via NfκB Activation in Blasts of Myelodysplastic Syndromes.

Asaka Kondo, Hideto Tamura, Taishi Yamashita, Chikako Sato, Zhao Wanhong, Takashi Tsuji, Eiji Shinya, Hidemi Takahashi, Koji Tamada, Lieping Chen, Kazuo Dan, Kiyoyuki Ogata

Blood (2009) 114 (22): 2766.

https://doi.org/10.1182/blood.V114.22.2766.2766

Published: 2009

Journal Articles

Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by T reg depletion

Roch Houot, Matthew J. Goldstein, Holbrook E. Kohrt, June H. Myklebust, Ash A. Alizadeh, Jack T. Lin, Jonathan M. Irish, James A. Torchia, Arne Kolstad, Lieping Chen, Ronald Levy

Blood (2009) 114 (16): 3431–3438.

https://doi.org/10.1182/blood-2009-05-223958

Published: 2009

Includes: Supplemental data

Journal Articles

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease

Tangsheng Yi, Ying Chen, Lin Wang, Gong Du, Daniel Huang, Dongchang Zhao, Heather Johnston, James Young, Ivan Todorov, Dale T. Umetsu, Lieping Chen, Yoichiro Iwakura, Fouad Kandeel, Stephen Forman, Defu Zeng

Blood (2009) 114 (14): 3101–3112.

https://doi.org/10.1182/blood-2009-05-219402

Published: 2009

Includes: Supplemental data

Journal Articles

PD-1 on dendritic cells impedes innate immunity against bacterial infection

Sheng Yao, Shengdian Wang, Yuwen Zhu, Liqun Luo, Gefeng Zhu, Sarah Flies, Haiying Xu, William Ruff, Megan Broadwater, In-Hak Choi, Koji Tamada, Lieping Chen

Blood (2009) 113 (23): 5811–5818.

https://doi.org/10.1182/blood-2009-02-203141

Published: 2009

Includes: Supplemental data

Journal Articles

B7-H4–deficient mice display augmented neutrophil-mediated innate immunity

Gefeng Zhu, Mathew M. Augustine, Takeshi Azuma, Liqun Luo, Sheng Yao, Sudarshan Anand, A. Cecilia Rietz, Jiaqiang Huang, Haiying Xu, Andrew S. Flies, Sarah J. Flies, Koji Tamada, Marco Colonna, Jan M. A. van Deursen, Lieping Chen

Blood (2009) 113 (8): 1759–1767.

https://doi.org/10.1182/blood-2008-01-133223

Published: 2009

Includes: Supplemental data

Journal Articles

Radiation-Free Anti-CD3-Conditioning Regimen Maintains Tissue Protection Mechanisms and Prevents GVHD: Role of Tissue Expression of B7H1

Ying Chen, Chia-Lei Lin, Nainong Li, Gong Du, Lieping Chen, Stephen Forman, Defu Zeng, MD

Blood (2008) 112 (11): 62.

https://doi.org/10.1182/blood.V112.11.62.62

Published: 2008

NARROW

Programmed Death-1 Homolog (PD-1H/VISTA) Blockade Confers a Synergistic Anti-Leukemia Effect with PD-1 Blockade

PD-1H (VISTA) Induces Immune Evasion in Acute Myeloid Leukemia

B7H1/B7.1 Interaction Alleviate Acute Gvhd in a PD-1 Dependent Manner

Host Tissue PD-1 Pathway Contribute To Murine Chronic Graft-Versus-Host Disease Via Th1+Th17+ Cells

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells

Tissue Parenchymal Cell Expression of B7-H1 Inhibits Infiltrating T Cell Expansion and Prevents Persistence of Graft-Versus-Host Disease

B7-H1 Molecules on Myeloma Cells Induce Aggressive Cell Behavior

CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies

Immunomodulation of NK Cells through 4-1BB (CD137) to Improve the Anti-Lymphoma Activity of Rituximab: Antibody-Based Anti-Lymphoma Synergy

Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4 + Foxp3 + regulatory T cells in the establishment of oral tolerance

B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance

Interferon-γ and tumor necrosis factor-α induce an immunoinhibitory molecule, B7-H1, via nuclear factor-κB activation in blasts in myelodysplastic syndromes

CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells

Therapeutic Potential of Anti-CD137 Antibody in Lymphoma.

Interferon-γ and Tumor Necrosis Factor-α Induce An Immunoinhibitory Molecule, B7-H1, Via NfκB Activation in Blasts of Myelodysplastic Syndromes.

Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by T reg depletion

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease

PD-1 on dendritic cells impedes innate immunity against bacterial infection

B7-H4–deficient mice display augmented neutrophil-mediated innate immunity

Radiation-Free Anti-CD3-Conditioning Regimen Maintains Tissue Protection Mechanisms and Prevents GVHD: Role of Tissue Expression of B7H1

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American Society of Hematology

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ASH Publications

American Society of Hematology

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