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Timothy P. Bender
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Journal Articles

Modulation of the Tumor Suppressor Protein PP2A Using a Small Molecule Agonist Overcomes Multi-Drug Resistance through Mitochondrial Permeability Transition Pore (MPTP) Dependent Induction of Apoptosis in Chronic Lymphocytic Leukemia

Kallesh D. Jayappa, PhD, Caroline Farrington, PhD, Vicki L. Gordon, BS, Shekhar Saha, PhD, Christopher Morris, BS, Krista M. Isaac, MD, Timothy P. Bender, PhD, Michael E. Williams, MD, Craig A. Portell, MD, Goutham Narla, MD PhD, Michael J. Weber, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–17.
https://doi.org/10.1182/blood-2020-138954
Published: 2020
Journal Articles

A Multi-Drug Tolerant Phenotype Is Induced By Diverse Microenvironmental Agonists in Chronic Lymphocytic Leukemia and Mantle Cell Lymphoma

Kallesh D. Jayappa, DVM, PhD, Konrad J. Cios, BSc (2019), Vicki L. Gordon, BSc, Puja C. Arora, MD, Timothy P. Bender, PhD, Michael E. Williams, MD, Craig A. Portell, MD, Michael J. Weber, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4120.
https://doi.org/10.1182/blood-2018-99-119521
Published: 2018
Journal Articles

Drug Combinations Co-Targeting Myeloid Cell Leukemia-1 (Mcl-1) Protein Can Overcome Microenvironmentally-Induced Multi-Drug Tolerance in Non-Hodgkin Lymphomas

Kallesh D. Jayappa, DVM, PhD, Craig A. Portell, MD, Vicki L. Gordon, BSc, Goutham Narla, MD PhD, Timothy P. Bender, PhD, Michael E. Williams, MD, Michael J. Weber, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2649.
https://doi.org/10.1182/blood-2018-99-116759
Published: 2018
Journal Articles

Extrinsic Factors in the In Vivo Macroenvironment Generate Phenotypic Resistance to BTK/Bcl-2 Targeted Therapies in Chronic Lymphocytic Leukemia and Mantle Cell Lymphoma

Kallesh D. Jayappa, DVM, PhD, Craig A. Portell, MD, Vicki L Gordon, BS, Brian J Capaldo, PhD, Stefan Bekiranov, PhD, Julia D Wulfkuhle, Rosa I Gallagher, Emanuel F. Petricoin, PhD, Timothy P. Bender, PhD, Michael E. Williams, MD, Michael J. Weber, PhD
Journal: Blood
Blood (2016) 128 (22): 754.
https://doi.org/10.1182/blood.V128.22.754.754
Published: 2016
Journal Articles

Ligands That Mimic the Tissue Microenvironment of Replicating Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL) Protect Ex Vivo Patient Cell Samples from the Cytotoxicity of Combined Treatment with Ibrutinib and Venetoclax (ABT-199)

Kallesh D. Jayappa, PhD, Craig A. Portell, MD, Vicki Gordon, B.S., Michael E. Williams, MD, Emanuel F. Petricoin, PhD, Timothy P. Bender, PhD, Michael J. Weber, PhD
Journal: Blood
Blood (2015) 126 (23): 448.
https://doi.org/10.1182/blood.V126.23.448.448
Published: 2015
Journal Articles

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells

Eric F. Tewalt, Jarish N. Cohen, Sherin J. Rouhani, Cynthia J. Guidi, Hui Qiao, Shawn P. Fahl, Mark R. Conaway, Timothy P. Bender, Kenneth S. Tung, Anthony T. Vella, Adam J. Adler, Lieping Chen, Victor H. Engelhard
Journal: Blood
Blood (2012) 120 (24): 4772–4782.
https://doi.org/10.1182/blood-2012-04-427013
Published: 2012
Includes: Supplemental data
Journal Articles

A new window on c-Myb function

Timothy P. Bender
Journal: Blood
Blood (2010) 116 (8): 1190–1191.
https://doi.org/10.1182/blood-2010-06-287300
Published: 2010
Journal Articles

Requirement of c-Myb for p210 BCR/ABL -dependent transformation of hematopoietic progenitors and leukemogenesis

Maria Rosa Lidonnici, Francesca Corradini, Todd Waldron, Timothy P. Bender, Bruno Calabretta
Journal: Blood
Blood (2008) 111 (9): 4771–4779.
https://doi.org/10.1182/blood-2007-08-105072
Published: 2008
Includes: Supplemental data
Journal Articles

c-myb Transactivates the Human Cyclin A1 Promoter and Induces Cyclin A1 Gene Expression

Carsten Müller, Rong Yang, Gregory Idos, Nicola Tidow, Sven Diederichs, Olaf M. Koch, Walter Verbeek, Timothy P. Bender, H. Phillip Koeffler
Journal: Blood
Blood (1999) 94 (12): 4255–4262.
https://doi.org/10.1182/blood.V94.12.4255
Published: 1999