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Journal Articles

CMV exposure drives long-term CD57 + CD4 memory T-cell inflation following allogeneic stem cell transplant

Blood (2021) 138 (26): 2874–2885.

https://doi.org/10.1182/blood.2020009492

Published: 2021

Includes: Supplemental data

Journal Articles

Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction

Shok Ping Lim, Benedetta Costantini, Syed A. Mian, Pilar Perez Abellan, Shreyans Gandhi, Marc Martinez Llordella, Juan Jose Lozano, Rita Antunes dos Reis, Giovanni A. M. Povoleri, Thanos P. Mourikis, Ander Abarrategi, Linda Ariza-McNaughton, Susanne Heck, Jonathan M. Irish, Giovanna Lombardi, Judith C. W. Marsh, Dominique Bonnet, Shahram Kordasti, Ghulam J. Mufti

Blood (2020) 136 (7): 885–897.

https://doi.org/10.1182/blood.2019001347

Published: 2020

Includes: Supplemental data

Journal Articles

Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling

June H. Myklebust, Joshua Brody, Holbrook E. Kohrt, Arne Kolstad, Debra K. Czerwinski, Sébastien Wälchli, Michael R. Green, Gunhild Trøen, Knut Liestøl, Klaus Beiske, Roch Houot, Jan Delabie, Ash A. Alizadeh, Jonathan M. Irish, Ronald Levy

Blood (2017) 129 (6): 759–770.

https://doi.org/10.1182/blood-2016-05-718494

Published: 2017

Includes: Supplemental data

Journal Articles

Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment

Blood (2016) 128 (9): 1193–1205.

https://doi.org/10.1182/blood-2016-03-703702

Published: 2016

Includes: Supplemental data

Journal Articles

Mass Cytometry of Acute Myeloid Leukemia Captures Early Therapy Response in Rare Cell Subsets

Paul Brent Ferrell, MD, Kirsten E. Diggins, Hannah G. Polikowsky, Jonathan M. Irish, PhD

Blood (2014) 124 (21): 2381.

https://doi.org/10.1182/blood.V124.21.2381.2381

Published: 2014

Journal Articles

Potentiated B-Cell Antigen Receptor Signaling In Mantle Cell Lymphoma Is Associated With Overexpression Of Surface CD79B and IgM

June Helen Myklebust, PhD, Joshua Brody, MD, Ash A. Alizadeh, MD, PhD, Debra K Czerwinski, Arne Kolstad, MD, PhD, Michael R Green, Ph.D., Roch Houot, MD, PhD, Jan Delabie, MD, PhD, Holbrook E Kohrt, MD, PhD, Jonathan M. Irish, PhD, Ronald Levy, MD

Blood (2013) 122 (21): 1768.

https://doi.org/10.1182/blood.V122.21.1768.1768

Published: 2013

Journal Articles

Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma

Michael R. Green, Andrew J. Gentles, Ramesh V. Nair, Jonathan M. Irish, Shingo Kihira, Chih Long Liu, Itai Kela, Erik S. Hopmans, June H. Myklebust, Hanlee Ji, Sylvia K. Plevritis, Ronald Levy, Ash A. Alizadeh

Blood (2013) 121 (9): 1604–1611.

https://doi.org/10.1182/blood-2012-09-457283

Published: 2013

Includes: Supplemental data

Journal Articles

High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells

June H. Myklebust, Jonathan M. Irish, Joshua Brody, Debra K. Czerwinski, Roch Houot, Holbrook E. Kohrt, John Timmerman, Jonathan Said, Michael R. Green, Jan Delabie, Arne Kolstad, Ash A. Alizadeh, Ronald Levy

Blood (2013) 121 (8): 1367–1376.

https://doi.org/10.1182/blood-2012-04-421826

Published: 2013

Includes: Supplemental data

Journal Articles

Clinical Translation of a Prognostic Follicular Lymphoma Signaling Profile

Jonathan M Irish, Ph.D., Debra K Czerwinski, Garry P. Nolan, Ph.D., Ronald Levy, MD

Blood (2010) 116 (21): 636.

https://doi.org/10.1182/blood.V116.21.636.636

Published: 2010

Journal Articles

Therapeutic Potential of Anti-CD137 Antibody in Lymphoma.

Roch Houot, MD, Matthew J Goldstein, Holbrook E Kohrt, MD, June H Myklebust, PhD, Ash A Alizadeh, MD, PhD, Jack T Lin, PhD, Jonathan M Irish, PhD, James A Torchia, Arne Kolstad, MD, PhD, Lieping Chen, MD, PhD, Ronald Levy, MD

Blood (2009) 114 (22): 722.

https://doi.org/10.1182/blood.V114.22.722.722

Published: 2009

Journal Articles

A Subpopulation of Follicular Lymphoma Tumor Infiltrating T Cells Shows Suppressed Common Gamma Chain Cytokine Signaling.

June H Myklebust, PhD, Jonathan M Irish, PhD, Roch Houot, MD, Joshua Brody, MD, Debra K Czerwinski, Ash A Alizadeh, MD, PhD, Arne Kolstad, MD, PhD, Ronald Levy, MD

Blood (2009) 114 (22): 759.

https://doi.org/10.1182/blood.V114.22.759.759

Published: 2009

Journal Articles

Distinct Signaling Profiles and Drug Responses Identify Subpopulations of Pediatric T-Cell Acute Lymphoblastic Leukemia and Lymphoma Patients.

Jason Law, MD, Kristin Ammon, MD, Matt Zinter, Jason Wen, Brian Cook, Jonathan M Irish, PhD, Michelle L. Hermiston, MD, PhD

Blood (2009) 114 (22): 1595.

https://doi.org/10.1182/blood.V114.22.1595.1595

Published: 2009

Journal Articles

Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by T reg depletion

Roch Houot, Matthew J. Goldstein, Holbrook E. Kohrt, June H. Myklebust, Ash A. Alizadeh, Jack T. Lin, Jonathan M. Irish, James A. Torchia, Arne Kolstad, Lieping Chen, Ronald Levy

Blood (2009) 114 (16): 3431–3438.

https://doi.org/10.1182/blood-2009-05-223958

Published: 2009

Includes: Supplemental data

Journal Articles

Signaling Diversity in Human Lymphoma B Cells and in Tumor Infiltrating T Cells Correlates with Follicular Lymphoma Patient Clinical Outcomes

Jonathan M. Irish, PhD, Roch Houot, MD, June H. Myklebust, PhD, Debra K. Czerwinski, Garry P. Nolan, PhD, Ronald Levy, MD

Blood (2008) 112 (11): 377.

https://doi.org/10.1182/blood.V112.11.377.377

Published: 2008

Journal Articles

A Profile of 648 Signaling Network Events Identifies Cell Subsets with Diverse, Abnormal Responses to Lymphocyte Stimuli within Follicular Lymphoma Tumors.

Jonathan M. Irish, PhD, Faye Y. Hsu, Ph.D., Jeff P. Sharman, M.D., Roch Houot, M.D., Joshua D. Brody, M.D., Debra K. Czerwinski, Garry P. Nolan, Ph.D., Ronald Levy, M.D.

Blood (2007) 110 (11): 356.

https://doi.org/10.1182/blood.V110.11.356.356

Published: 2007

Journal Articles

A Novel Assay for Juvenile Myelomonocytic Leukemia Based on Aberrant Signaling Networks Measured Via Phospho-Specific Flow Cytometry Reduces Diagnosis Time from Weeks to Days.

Nikesh Kotecha, Nikki J. Flores, Jonathan M. Irish, PhD, Debbie Sakaguchi, MD, Sophie Archambeault, Ernesto Diaz-Flores, PhD, Marc Coram, PhD, Kevin M. Shannon, MD, Garry P. Nolan, PhD, Mignon L. Loh, MD

Blood (2007) 110 (11): 546.

https://doi.org/10.1182/blood.V110.11.546.546

Published: 2007

Journal Articles

K-Ras G12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells

Margaret E. M. Van Meter, Ernesto Díaz-Flores, Joehleen A. Archard, Emmanuelle Passegué, Jonathan M. Irish, Nikesh Kotecha, Garry P. Nolan, Kevin Shannon, Benjamin S. Braun

Blood (2006) 109 (9): 3945–3952.

https://doi.org/10.1182/blood-2006-09-047530

Published: 2006

Includes: Supplemental data

Journal Articles

Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53

Jonathan M. Irish, Nina Ånensen, Randi Hovland, Jørn Skavland, Anne-Lise Børresen-Dale, Øystein Bruserud, Garry P. Nolan, Bjørn T. Gjertsen

Blood (2006) 109 (6): 2589–2596.

https://doi.org/10.1182/blood-2006-02-004234

Published: 2006

Includes: Supplemental data

Journal Articles

Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells

Jonathan M. Irish, Debra K. Czerwinski, Garry P. Nolan, Ronald Levy

Blood (2006) 108 (9): 3135–3142.

https://doi.org/10.1182/blood-2006-02-003921

Published: 2006

Includes: Supplemental data

Journal Articles

Rapid, Sustained B Cell Receptor Signaling in Lymphoma B Cells Differs from Normal Signaling in Tumor Infiltrating Nonmalignant B Cells.

Jonathan M. Irish, PhD, Debra K. Czerwinski, Garry P. Nolan, PhD, Ronald Levy, MD

Blood (2005) 106 (11): 283.

https://doi.org/10.1182/blood.V106.11.283.283

Published: 2005

NARROW

CMV exposure drives long-term CD57 + CD4 memory T-cell inflation following allogeneic stem cell transplant

Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction

Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling

Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment

Mass Cytometry of Acute Myeloid Leukemia Captures Early Therapy Response in Rare Cell Subsets

Potentiated B-Cell Antigen Receptor Signaling In Mantle Cell Lymphoma Is Associated With Overexpression Of Surface CD79B and IgM

Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma

High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells

Clinical Translation of a Prognostic Follicular Lymphoma Signaling Profile

Therapeutic Potential of Anti-CD137 Antibody in Lymphoma.

A Subpopulation of Follicular Lymphoma Tumor Infiltrating T Cells Shows Suppressed Common Gamma Chain Cytokine Signaling.

Distinct Signaling Profiles and Drug Responses Identify Subpopulations of Pediatric T-Cell Acute Lymphoblastic Leukemia and Lymphoma Patients.

Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by T reg depletion

Signaling Diversity in Human Lymphoma B Cells and in Tumor Infiltrating T Cells Correlates with Follicular Lymphoma Patient Clinical Outcomes

A Profile of 648 Signaling Network Events Identifies Cell Subsets with Diverse, Abnormal Responses to Lymphocyte Stimuli within Follicular Lymphoma Tumors.

A Novel Assay for Juvenile Myelomonocytic Leukemia Based on Aberrant Signaling Networks Measured Via Phospho-Specific Flow Cytometry Reduces Diagnosis Time from Weeks to Days.

K-Ras G12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells

Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53

Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells

Rapid, Sustained B Cell Receptor Signaling in Lymphoma B Cells Differs from Normal Signaling in Tumor Infiltrating Nonmalignant B Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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