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Journal Articles

IPSS-M risk and specific sex-associated somatic mutations predict response to ESA therapy in LR-MDS: building a new score

Blood (2025) 146 (14): 1693–1706.

https://doi.org/10.1182/blood.2024027540

Published: 2025

Includes: Supplemental data

Journal Articles

The acute myeloid leukemia microenvironment impairs neutrophil maturation and function through NF-κB signaling

Blood (2025) 146 (14): 1707–1721.

https://doi.org/10.1182/blood.2024028199

Published: 2025

Includes: Supplemental data

Journal Articles

AML with mutated TP53, therapy-related, with basophilic differentiation, partial CD22, and ring sideroblasts

Zhaodong Xu, Eric McGinnis

Blood (2025) 146 (14): 1737.

https://doi.org/10.1182/blood.2025029483

Published: 2025

Journal Articles

Fetal context conveys heritable protection against MLL-rearranged AML that depends on MLL3

Jonny Mendoza-Castrejon, Wei Yang, Elisabeth D Denby, Helen C. Wang, Emily B. Casey, Rohini Muthukumar, Riddhi M. Patel, Jihye Yoon, Yanan Li, J. Michael White, Ran Chen, Luis Francisco Zirnberger Batista, Jeffrey A Magee

Blood blood.2025029686.

https://doi.org/10.1182/blood.2025029686

Published: 2025

Includes: Supplemental data

Journal Articles

Genome-wide analysis defines genetic determinants of MPN subtypes and identifies a sex-specific association at CDH22/CD40

Blood blood.2025028489.

https://doi.org/10.1182/blood.2025028489

Published: 2025

Includes: Supplemental data

Journal Articles

Clinical significance of preleukemic somatic GATA1 mutations in children with Down syndrome

Natalina Elliott, Neha Bhatnagar, Gemma Buck, David Cruz Hernandez, Kelly Perkins, Adam J. de Smith, Amelie Chaussade, Laure Nizery, Marlen Metzner, Catherine Garnett, Alice Norton, Alison Kennedy, Triya Chakravorty, Dylan Zhao, Lars Hanssen, Georgina Hall, Paresh Vyas, Irene Roberts

Blood (2025) 146 (13): 1561–1574.

https://doi.org/10.1182/blood.2025029250

Published: 2025

Includes: Supplemental data

Journal Articles

Time to complete remission is an independent determinant of survival after intensive chemotherapy in AML

Rithin Nedumannil, Michael Ashby, James Rowland, Jacques A. J. Malherbe, Jared Fairbank, Kelli Gray, Sun Loo, Matthew Wright, John Reynolds, Devendra Hiwase, Paula Marlton, Shaun Fleming, Ashish Bajel, Andrew H. Wei

Blood (2025) 146 (13): 1625–1629.

https://doi.org/10.1182/blood.2025028594

Published: 2025

Includes: Supplemental data

Journal Articles

Thrombocytopenia in myelofibrosis is characterized by inflammatory megakaryocytes with reduced G6B expression

Lilian Varricchio, Gohar Mosoyan, Sebastian Elghaity-Beckley, Md. Babu Mia, Shivani Handa, Christian Salib, John Mascarenhas, Ronald Hoffman

Blood (2025) 146 (13): 1612–1624.

https://doi.org/10.1182/blood.2024027363

Published: 2025

Includes: Supplemental data

Journal Articles

CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias

Blood blood.2025028954.

https://doi.org/10.1182/blood.2025028954

Published: 2025

Includes: Supplemental data

Journal Articles

Fusion Gene Depletion Eliminates Stemness and Induces Bidirectional Differentiation of Acute Myeloid Leukemia

Polina K Derevyanko, Laura E Swart, L. Daniel Mata Casimiro, Anita van Oort, Manisha Du Plessis, Luca van den Brink, Minoo Ashtiani, C. Michel Zwaan, Anja Krippner-Heidenreich, Constanze Bonifer, Ray Michel Schiffelers, Josef Josef Vormoor, Sophie Kellaway, Olaf Heidenreich

Blood blood.2025028988.

https://doi.org/10.1182/blood.2025028988

Published: 2025

Includes: Supplemental data

Journal Articles

Determining telomere content and genomics of myeloid neoplasia by whole-genome sequencing

Blood blood.2025028644.

https://doi.org/10.1182/blood.2025028644

Published: 2025

Includes: Supplemental data

Journal Articles

FLAG-IDA plus venetoclax for children, adolescents, and young adults with newly diagnosed AML

Blood blood.2025029391.

https://doi.org/10.1182/blood.2025029391

Published: 2025

Includes: Supplemental data

Journal Articles

Loss of BAP1 defines a unique subtype of TP53 -mutated de novo AML and confers sensitivity to BCL-xL inhibitors

Jaclyn Andricovich, Coen Johannes Lap, Alexandros Tzatsos

Blood (2025) 146 (12): 1493–1510.

https://doi.org/10.1182/blood.2024026417

Published: 2025

Includes: Supplemental data

Journal Articles

Targeting STK17B kinase activates ferroptosis and suppresses drug resistance in multiple myeloma

Zhibo Yan, Zhannan Han, Yihui Wang, Maja Beus, Yu Zhang, Alfredo Picado, Carrow I. Wells, Jian Wu, Loren B. Weidenhammer, Karla M. Pires, Elizabeth A. Leibold, Liang Liu, David M. Gooden, Ivan Spasojevic, Erik Soderblom, Yubin Kang, Lawrence H Boise, Timothy M. Willson, Mikhail A. Nikiforov

Blood blood.2025029950.

https://doi.org/10.1182/blood.2025029950

Published: 2025

Includes: Supplemental data

Journal Articles

Transposable elements as novel therapeutic targets for PARPi-induced synthetic lethality in PcG-mutated blood cancer

Blood (2025) 146 (11): 1314–1330.

https://doi.org/10.1182/blood.2025028560

Published: 2025

Includes: Supplemental data

Journal Articles

An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4- mediated ferritinophagy as a dependence in Tet2 -deficient hematopoiesis

Justin Loke, Peter G. Kim, Thuy T. P. Nguyen, Meaghan Boileau, Marie McConkey, Aidan Miller, Wesley Shin, Christopher B. Hergott, Maria Ericsson, Anja Nordstrom, Paula Montero Llopis, Scott A. Armstrong, Joseph D. Mancias, Benjamin L. Ebert

Blood (2025) 146 (10): 1174–1186.

https://doi.org/10.1182/blood.2024028033

Published: 2025

Includes: Supplemental data

Journal Articles

Posttranscriptional depletion of ribosome biogenesis factors engenders therapeutic vulnerabilities in NPM1 -mutant AML

Blood (2025) 146 (10): 1239–1252.

https://doi.org/10.1182/blood.2024026113

Published: 2025

Includes: Supplemental data

Journal Articles

Impact of ASXL1 at diagnosis in patients with CML receiving frontline potent TKIs: high risk of kinase domain mutations

Blood blood.2025030259.

https://doi.org/10.1182/blood.2025030259

Published: 2025

Includes: Supplemental data

Journal Articles

Lineage switch from KMT2A -rearranged congenital B-ALL to AML in an infant: a genomic perspective

Rohan Kodgule, Kiran R. Vij

Blood (2025) 146 (9): 1142.

https://doi.org/10.1182/blood.2025029472

Published: 2025

Journal Articles

Correlates and consequences of clonal hematopoiesis expansion rate: a 16-year longitudinal study of 6976 women

Blood (2025) 146 (9): 1078–1087.

https://doi.org/10.1182/blood.2025028417

Published: 2025

Includes: Supplemental data

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IPSS-M risk and specific sex-associated somatic mutations predict response to ESA therapy in LR-MDS: building a new score

The acute myeloid leukemia microenvironment impairs neutrophil maturation and function through NF-κB signaling

AML with mutated TP53, therapy-related, with basophilic differentiation, partial CD22, and ring sideroblasts

Fetal context conveys heritable protection against MLL-rearranged AML that depends on MLL3

Genome-wide analysis defines genetic determinants of MPN subtypes and identifies a sex-specific association at CDH22/CD40

Clinical significance of preleukemic somatic GATA1 mutations in children with Down syndrome

Time to complete remission is an independent determinant of survival after intensive chemotherapy in AML

Thrombocytopenia in myelofibrosis is characterized by inflammatory megakaryocytes with reduced G6B expression

CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias

Fusion Gene Depletion Eliminates Stemness and Induces Bidirectional Differentiation of Acute Myeloid Leukemia

Determining telomere content and genomics of myeloid neoplasia by whole-genome sequencing

FLAG-IDA plus venetoclax for children, adolescents, and young adults with newly diagnosed AML

Loss of BAP1 defines a unique subtype of TP53 -mutated de novo AML and confers sensitivity to BCL-xL inhibitors

Targeting STK17B kinase activates ferroptosis and suppresses drug resistance in multiple myeloma

Transposable elements as novel therapeutic targets for PARPi-induced synthetic lethality in PcG-mutated blood cancer

An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4- mediated ferritinophagy as a dependence in Tet2 -deficient hematopoiesis

Posttranscriptional depletion of ribosome biogenesis factors engenders therapeutic vulnerabilities in NPM1 -mutant AML

Impact of ASXL1 at diagnosis in patients with CML receiving frontline potent TKIs: high risk of kinase domain mutations

Lineage switch from KMT2A -rearranged congenital B-ALL to AML in an infant: a genomic perspective

Correlates and consequences of clonal hematopoiesis expansion rate: a 16-year longitudinal study of 6976 women

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